Drug General Information (ID: D0617)
  Drug Name
Ethanol
  Drug Type Small molecule
  Drug Synonymous
Aethanol; Aethylalkohol; Alcohol; Alcohols; Algrain; Alkohol; Anhydrol; EOH; EOX; EtOH; Etanol; Etanolo; Ethicap; Ethylalcohol; Ethylol; Hinetoless; Hydroxyethane; Jaysol; Methylcarbinol; QMHAIh; Sekundasprit; Spirit; Spirt; Synasol; Tecsol; Thanol; Absolute alcohol; Absolute ethanol; Aethanol [German]; Alcare Hand Degermer; Alcohol [USP]; Alcohol anhydrous; Alcohol dehydrated; Alcohol etilico; Alcool ethylique; Alcool etilico; Alkohol [German]; Alkoholu etylowego; Anhydrous alcohol; Anhydrous ethanol; Cologne Spirit; Colognespirits; Dehydrated alcohol; Dehydrated ethanol; Denatured alcohol; Denatured ethanol; Desinfektol EL; Distilled spirits; Etanolo [Italian]; Ethanol Absolute; Ethanol Absolute Bp; Ethanol Anhydrous; Ethanol Extra Pure; Ethanol Vapor; Ethanol [JAN]; Ethanol solution; Ethanolum anhydricum; Ethyl alc; Ethyl alcohol; Ethyl alcohol usp; Ethyl hydrate; Ethyl hydroxide; Ethylalcohol [Dutch]; Ethyloxy Group; Etylowy alkohol; Fermentation alcohol; Grain alcohol; HYDROXYETHYL GROUP; Infinity Pure; Jaysol S; Methylated spirit; Molasses alcohol; Oxydimethylene Group; Potato alcohol; Reagent Alcohol; SY Fresh M; Spirits of wine; Spiritus vini; Tecsol C; AHD 2000; Anhydrol PM 4085; CDA 19; E7148_ALDRICH; Esumiru WK 88; Ethanol 200 proof; IMS 99; LTBB002977; SDA 3A; Alcohol (USP); Alcohol, Absolute; Alcohol, Grain; Alcohol, anhydrous; Alcohol, dehydrated; Alcohol, diluted; Alcohol, ethyl; Alcohols, C30; CDA 19-200; Ethanol (9CI); Ethanol, undenatured; Ru-Tuss Expectorant; SDA 40-2; SDM No. 37; ALCOHOL 5% IN D5-W; Alcohols, C1-3; Alcohols, C6-9; (C6-C9)Alkyl alcohol; 1-Hydroxyethane; 100C.NPA
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  Disease Class GC00: Cystitis; MG30: Chronic pain
  Therapeutic Class Analgesics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C2H6O
  InChI 1S/C2H6O/c1-2-3/h3H,2H2,1H3
  InChIKey LFQSCWFLJHTTHZ-UHFFFAOYSA-N
  Canonical SMILES CCO
  External Link
Pubchem ID 702
CAS Number 64-17-5
CHEBI ID 16236
TTD ID D00AMQ
INTEDE ID DR0655
VARIDT ID DR00377

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
AM004  Affected intra/extra-hepatic metabolism
AM005  Affected excretion pathways
AM006  Pharmacodynamic additive effects
BM001  Altered gastrointestinal dynamics
BM018  Non-CYP450 enzyme inhibition
BM025  Decreased metabolism (Unspecific)
BM031  Increased renal excretion (Unspecific)
BM038  Additive CNS depression effects
BM042  Additive hypotensive effects
BM050  Increased risk of bleeding
BM054  Increased risk of GI mucosal injury/bleeding risk
BM055  Increased risk of hepatotoxicity
BM064  Increased risk of hypoglycemia
BM076  Increased risk of prolong QT interval
BM083  Potentiated the pharmacological effects (Unspecific)
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Ethanol
      Affected gastrointestinal absorption
   Altered gastrointestinal dynamics Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0597
 
Erythromycin
 
C37H67NO13
 
12560 
Minor    Inter Info   
[190]
      Affected intra/extra-hepatic metabolism
   Non-CYP450 enzyme inhibition Drug Num:  13
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0162
 
Benznidazole
 
C12H12N4O3
 
31593 
Major    Inter Info   
[30], [31], [32], [33], [34], [35], [36], [37], [38]
D0689
 
Fomepizole
 
C4H6N2
 
3406 
Major    Inter Info   
[57]
D1051
 
Metronidazole
 
C6H9N3O3
 
4173 
Major    Inter Info   
[30], [31], [32], [33], [34], [35], [36], [37], [38]
D1135
 
Nifurtimox
 
C10H13N3O5S
 
6842999 
Major    Inter Info   
[63]
D0282
 
Cefmetazole
 
C15H17N7O5S3
 
42008 
Moderate    Inter Info   
[125], [126], [127], [128], [129], [130], [131], [132], [133]
D0274
 
Cefamandole
 
C18H18N6O5S2
 
456255 
Moderate    Inter Info   
[125], [126], [127], [128], [129], [130], [131], [132], [133]
D0284
 
Cefoperazone
 
C25H27N9O8S2
 
44187 
Moderate    Inter Info   
[125], [126], [127], [128], [129], [130], [131], [132], [133]
D0286
 
Cefotetan
 
C17H17N7O8S4
 
53025 
Moderate    Inter Info   
[125], [126], [127], [128], [129], [130], [131], [132], [133]
D1052
 
Metronidazole (topical)
 
C6H9N3O3
 
4173 
Moderate    Inter Info   
[33], [34], [37]
D1587
 
Tinidazole
 
C8H13N3O4S
 
5479 
Moderate    Inter Info   
[30], [31], [32], [33], [34], [36], [175], [37], [38]
D0337
 
Cimetidine
 
C10H16N6S
 
2756 
Minor    Inter Info   
[187], [188]
D0001
 
Abacavir
 
C14H18N6O
 
441300 
Minor    Inter Info   
[191]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Minor    Inter Info   
[195]
   Decreased metabolism (Unspecific) Drug Num:  6
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0485
 
Dienogest
 
C20H25NO2
 
68861 
Minor    Inter Info   
[192], [193], [194]
D0619
 
Ethinylestradiol
 
C20H24O2
 
5991 
Minor    Inter Info   
[192], [193], [194]
D1156
 
Norgestimate
 
C23H31NO3
 
6540478 
Minor    Inter Info   
[192], [193], [194]
D1157
 
Norgestrel
 
C21H28O2
 
13109 
Minor    Inter Info   
[194]
D0922
 
Levonorgestrel
 
C21H28O2
 
13109 
Minor    Inter Info   
[194]
D1154
 
Norethisterone
 
C20H26O2
 
6230 
Minor    Inter Info   
[192], [193], [194]
      Affected excretion pathways
   Increased renal excretion (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0508
 
Disopyramide
 
C21H29N3O
 
3114 
Minor    Inter Info   
[189]
      Pharmacodynamic additive effects
   Additive CNS depression effects Drug Num:  250
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0224
 
Butabarbital
 
C10H16N2O3
 
2479 
Major    Inter Info   
[15], [16], [17], [18], [19]
D0225
 
Butalbital
 
C11H16N2O3
 
2481 
Major    Inter Info   
[15], [16], [17], [18], [19]
D0401
 
Cycloserine
 
C3H6N2O2
 
6234 
Major    Inter Info   
[13], [20]
D0467
 
Dextropropoxyphene
 
C22H29NO2
 
10100 
Major    Inter Info   
[21]
D0071
 
Amobarbital
 
C11H18N2O3
 
2164 
Major    Inter Info   
[15], [16], [17], [18], [19]
D0219
 
Buprenorphine
 
C29H41NO4
 
644073 
Major    Inter Info   
[39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54]
D0665
 
Flibanserin
 
C20H21F3N4O
 
6918248 
Major    Inter Info   
[56]
D0772
 
Hydrocodone
 
C18H21NO3
 
5284569 
Major    Inter Info   
[58]
D0909
 
Levacetylmethadol
 
C23H31NO2
 
15130 
Major    Inter Info   
[56], [61]
D1265
 
Phenobarbital
 
C12H12N2O3
 
4763 
Major    Inter Info   
[15], [16], [17], [18], [19]
D1485
 
Sodium oxybate
 
C4H7NaO3
 
23663870 
Major    Inter Info   
[65], [66]
D1731
 
Ethionamide
 
C8H10N2S
 
2761171 
Major    Inter Info   
[67], [68]
D0776
 
Hydromorphone
 
C17H19NO3
 
5284570 
Major    Inter Info   
[69], [70], [71]
D1024
 
Methohexital
 
C14H18N2O3
 
9034 
Major    Inter Info   
[15], [16], [17], [18], [19]
D1040
 
Methylphenobarbital
 
C13H14N2O3
 
8271 
Major    Inter Info   
[15], [16], [17]
D1089
 
Morphine
 
C17H19NO3
 
5288826 
Major    Inter Info   
[74], [75]
D1248
 
Pentobarbital
 
C11H18N2O3
 
4737 
Major    Inter Info   
[15], [16], [17], [18], [19]
D1340
 
Primidone
 
C12H14N2O2
 
4909 
Major    Inter Info   
[15], [16], [17], [18], [19]
D1453
 
Secobarbital
 
C12H18N2O3
 
5193 
Major    Inter Info   
[15], [16], [17], [18], [19]
D1573
 
Thiopental
 
C11H18N2O2S
 
3000715 
Major    Inter Info   
[15], [16], [17], [18], [19]
D0035
 
Alfentanil
 
C21H32N6O3
 
51263 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D0045
 
Alprazolam
 
C17H13ClN4
 
2118 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0068
 
Amitriptyline
 
C20H23N
 
2160 
Moderate    Inter Info   
[96], [97], [98], [99], [100], [101], [102]
D0072
 
Amoxapine
 
C17H16ClN3O
 
2170 
Moderate    Inter Info   
[96], [97], [98], [99], [100], [101], [102]
D0097
 
Apomorphine
 
C17H17NO2
 
6005 
Moderate    Inter Info   
[105]
D0123
 
Atropine
 
C17H23NO3
 
174174 
Moderate    Inter Info   
[117]
D0135
 
Azatadine
 
C20H22N2
 
19861 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0143
 
Baclofen
 
C10H12ClNO2
 
2284 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0160
 
Benzatropine
 
C21H25NO
 
1201549 
Moderate    Inter Info   
[25], [117], [13]
D0165
 
Benzphetamine
 
C17H21N
 
5311017 
Moderate    Inter Info   
[121], [103], [122]
D0183
 
Biperiden
 
C21H29NO
 
2381 
Moderate    Inter Info   
[117]
D0205
 
Brimonidine (ophthalmic)
 
C11H10BrN5
 
2435 
Moderate    Inter Info   
[123], [13], [124]
D0206
 
Brimonidine (topical)
 
C11H10BrN5
 
2435 
Moderate    Inter Info   
[123], [13], [124]
D0214
 
Brompheniramine
 
C16H19BrN2
 
6834 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0222
 
Buspirone
 
C21H31N5O2
 
2477 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0226
 
Butorphanol
 
C21H29NO2
 
5361092 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D0255
 
Carbamazepine
 
C15H12N2O
 
2554 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0259
 
Carbinoxamine
 
C16H19ClN2O
 
2564 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0263
 
Carisoprodol
 
C12H24N2O4
 
2576 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0305
 
Cetirizine
 
C21H25ClN2O3
 
2678 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0317
 
Chlordiazepoxide
 
C16H14ClN3O
 
2712 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0322
 
Chlorphenesin
 
C9H11ClO3
 
7697 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Moderate    Inter Info   
[137], [138]
D0327
 
Chlorzoxazone
 
C7H4ClNO2
 
2733 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0351
 
Clemastine
 
C21H26ClNO
 
26987 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0353
 
Clidinium
 
C22H26NO3+
 
2784 
Moderate    Inter Info   
[117]
D0356
 
Clobazam
 
C16H13ClN2O2
 
2789 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0365
 
Clorazepic acid
 
C16H11ClN2O3
 
2809 
Moderate    Inter Info   
[86], [90], [91]
D0370
 
Clozapine
 
C18H19ClN4
 
135398737 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0379
 
Codeine
 
C18H21NO3
 
5284371 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D0403
 
Cyproheptadine
 
C21H21N
 
2913 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0456
 
Dexbrompheniramine
 
C16H19BrN2
 
16960 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0459
 
Dexmedetomidine
 
C13H16N2
 
5311068 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0466
 
Dextromethorphan
 
C18H25NO
 
5360696 
Moderate    Inter Info   
[13], [26], [140]
D0473
 
Diazepam
 
C16H13ClN2O
 
3016 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0482
 
Dicyclomine
 
C19H35NO2
 
3042 
Moderate    Inter Info   
[117]
D0532
 
Doxylamine
 
C17H22N2O
 
3162 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0533
 
Dronabinol
 
C21H30O2
 
16078 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0575
 
Entacapone
 
C14H15N3O5
 
5281081 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0612
 
Eszopiclone
 
C17H17ClN6O3
 
969472 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0020
 
Acrivastine
 
C22H24N2O2
 
5284514 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0037
 
Alimemazine
 
C18H22N2S
 
5574 
Moderate    Inter Info   
[137], [138]
D0098
 
Apraclonidine
 
C9H10Cl2N4
 
2216 
Moderate    Inter Info   
[123], [13], [124]
D0105
 
Aripiprazole
 
C23H27Cl2N3O2
 
60795 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0112
 
Asenapine
 
C17H16ClNO
 
3036780 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0137
 
Azelastine (nasal)
 
C22H24ClN3O
 
2267 
Moderate    Inter Info   
[102], [120], [119]
D0154
 
Belladonna
 
C34H42N2O4
 
265028 
Moderate    Inter Info   
[117]
D0201
 
Brexanolone
 
C21H34O2
 
92786 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0202
 
Brexpiprazole
 
C25H27N3O2S
 
11978813 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0208
 
Brivaracetam
 
C11H20N2O2
 
9837243 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0212
 
Bromocriptine
 
C32H40BrN5O5
 
31101 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0248
 
Cannabidiol
 
C21H30O2
 
644019 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0262
 
Cariprazine
 
C21H32Cl2N4O
 
11154555 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0300
 
Cenobamate
 
C10H10ClN5O2
 
11962412 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0311
 
Chloral hydrate
 
C2H3Cl3O2
 
2707 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0316
 
Chlorcyclizine
 
C18H21ClN2
 
2710 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0318
 
Chlormezanone
 
C11H12ClNO3S
 
2717 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0323
 
Chlorpheniramine
 
C16H19ClN2
 
2725 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0359
 
Clofedanol
 
C17H20ClNO
 
2795 
Moderate    Inter Info   
[102], [120], [119]
D0362
 
Clonazepam
 
C15H10ClN3O3
 
2802 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0397
 
Cyclizine
 
C18H22N2
 
6726 
Moderate    Inter Info   
[117]
D0398
 
Cyclobenzaprine
 
C20H21N
 
2895 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0417
 
Dantrolene
 
C14H10N4O5
 
6914273 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0446
 
Desipramine
 
C18H22N2
 
2995 
Moderate    Inter Info   
[96], [97], [98], [99], [100], [101], [102]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0452
 
Deutetrabenazine
 
C19H27NO3
 
73437646 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0457
 
Dexfenfluramine
 
C12H16F3N
 
66265 
Moderate    Inter Info   
[121], [103], [122]
D0470
 
Dezocine
 
C16H23NO
 
3033053 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D0471
 
Diamorphine
 
C21H23NO5
 
5462328 
Moderate    Inter Info   
[78], [76], [80]
D0486
 
Diethylpropion
 
C13H19NO
 
7029 
Moderate    Inter Info   
[121], [103], [122]
D0493
 
Dihydrocodeine
 
C18H23NO3
 
5284543 
Moderate    Inter Info   
[78], [76], [80]
D0502
 
Diphenhydramine
 
C17H21NO
 
3100 
Moderate    Inter Info   
[117]
D0504
 
Diphenoxylate
 
C30H32N2O2
 
13505 
Moderate    Inter Info   
[102], [120], [119]
D0526
 
Doxepin (topical)
 
C19H21NO
 
667477 
Moderate    Inter Info   
[96], [101], [102]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0600
 
Esketamine
 
C13H16ClNO
 
182137 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0601
 
Eslicarbazepine
 
C15H14N2O2
 
9881504 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0604
 
Estazolam
 
C16H11ClN4
 
3261 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0639
 
Felbamate
 
C11H14N2O4
 
3331 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0662
 
Flavoxate
 
C24H25NO4
 
3354 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0697
 
Fosphenytoin
 
C16H15N2O6P
 
56339 
Moderate    Inter Info   
[26], [13], [155], [156], [157]
D0705
 
Gabapentin
 
C9H17NO2
 
3446 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0733
 
Glycopyrronium
 
C19H28NO3+
 
3494 
Moderate    Inter Info   
[25], [117], [13]
D0791
 
Iloperidone
 
C24H27FN2O4
 
71360 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0853
 
Isocarboxazid
 
C12H13N3O2
 
3759 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0879
 
Ketamine
 
C13H16ClNO
 
3821 
Moderate    Inter Info   
[26], [13], [165]
D0885
 
Lacosamide
 
C13H18N2O3
 
219078 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0901
 
Lemborexant
 
C22H20F2N4O2
 
56944144 
Moderate    Inter Info   
[26], [166]
D0912
 
Levetiracetam
 
C8H14N2O2
 
5284583 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0917
 
Levocetirizine
 
C21H25ClN2O3
 
1549000 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0918
 
Levodopa
 
C9H11NO4
 
6047 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0940
 
Lithium carbonate
 
CLi2O3
 
11125 
Moderate    Inter Info   
[102], [120], [119]
D0942
 
Lofexidine
 
C11H12Cl2N2O
 
30668 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0959
 
Lumateperone
 
C24H28FN3O
 
21302490 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0961
 
Lurasidone
 
C28H36N4O2S
 
213046 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0979
 
Maprotiline
 
C20H23N
 
4011 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1000
 
Mepenzolate
 
C21H26NO3+
 
4057 
Moderate    Inter Info   
[117]
D1006
 
Mepyramine
 
C17H23N3O
 
4992 
Moderate    Inter Info   
[102], [120], [119]
D1010
 
Mesoridazine
 
C21H26N2OS2
 
4078 
Moderate    Inter Info   
[137], [138]
D1012
 
Metamfetamine
 
C10H15N
 
10836 
Moderate    Inter Info   
[103], [122], [121]
D1019
 
Methdilazine
 
C18H20N2S
 
14677 
Moderate    Inter Info   
[137], [138]
D1026
 
Methotrimeprazine
 
C19H24N2OS
 
72287 
Moderate    Inter Info   
[137], [138]
D1030
 
Methoxyflurane
 
C3H4Cl2F2O
 
4116 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1031
 
Methscopolamine
 
C18H24NO4+
 
71183 
Moderate    Inter Info   
[117]
D1032
 
Methsuximide
 
C12H13NO2
 
6476 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1046
 
Metoclopramide
 
C14H22ClN3O2
 
4168 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1084
 
Molindone
 
C16H24N2O2
 
23897 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1169
 
Oliceridine
 
C22H30N2O2S
 
66553195 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1182
 
Opicapone
 
C15H10Cl2N4O6
 
135565903 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1183
 
Opium
 
NA
 
NA
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1188
 
Orphenadrine
 
C18H23NO
 
4601 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1202
 
Oxybutynin
 
C22H31NO3
 
4634 
Moderate    Inter Info   
[117]
D1208
 
Oxymorphone
 
C17H19NO4
 
5284604 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1215
 
Paliperidone
 
C23H27FN4O3
 
115237 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1224
 
Paraldehyde
 
C6H12O3
 
31264 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1252
 
Pentoxyverine
 
C20H31NO3
 
2562 
Moderate    Inter Info   
[102], [120], [119]
D1253
 
Perampanel
 
C23H15N3O
 
9924495 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1255
 
Pergolide
 
C19H26N2S
 
47811 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1262
 
Phendimetrazine
 
C12H17NO
 
30487 
Moderate    Inter Info   
[121], [103], [122]
D1264
 
Phenindamine
 
C19H19N
 
11291 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1292
 
Pimozide
 
C28H29F2N3O
 
16362 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Moderate    Inter Info   
[137], [138]
D1367
 
Quazepam
 
C17H11ClF4N2S
 
4999 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D1378
 
Ramelteon
 
C16H21NO2
 
208902 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1385
 
Rasagiline
 
C12H13N
 
3052776 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1390
 
Remifentanil
 
C20H28N2O5
 
60815 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1431
 
Rotigotine
 
C19H25NOS
 
59227 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1437
 
Safinamide
 
C17H19FN2O2
 
131682 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1455
 
Selegiline
 
C13H17N
 
26757 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1464
 
Sibutramine
 
C17H26ClN
 
5210 
Moderate    Inter Info   
[121], [103], [122]
D1502
 
St. John's Wort
 
NA
 
NA
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1524
 
Suvorexant
 
C23H23ClN6O2
 
24965990 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1535
 
Tapentadol
 
C14H23NO
 
9838022 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1536
 
Tasimelteon
 
C15H19NO2
 
10220503 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1560
 
Tetrabenazine
 
C19H27NO3
 
6018 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1569
 
Thalidomide
 
C13H10N2O4
 
5426 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1576
 
Thiothixene
 
C23H29N3O2S2
 
941651 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1578
 
Tiagabine
 
C20H25NO2S2
 
60648 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1607
 
Tolterodine
 
C22H31NO
 
443879 
Moderate    Inter Info   
[117]
D1673
 
Valbenazine
 
C24H38N2O4
 
24795069 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1675
 
Valerian
 
NA
 
NA
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1694
 
Vigabatrin
 
C6H11NO2
 
5665 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1716
 
Zaleplon
 
C17H15N5O
 
5719 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1719
 
Ziconotide
 
C102H172N36O32S7
 
16135415 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1730
 
Zonisamide
 
C8H8N2O3S
 
5734 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0618
 
Ethchlorvynol
 
C7H9ClO
 
5281077 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0620
 
Ethosuximide
 
C7H11NO2
 
3291 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0621
 
Ethotoin
 
C11H12N2O2
 
3292 
Moderate    Inter Info   
[26], [13], [155], [156], [157]
D0625
 
Etomidate
 
C14H16N2O2
 
667484 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0641
 
Fenfluramine
 
C12H16F3N
 
3337 
Moderate    Inter Info   
[121], [103], [122]
D0646
 
Fentanyl
 
C22H28N2O
 
3345 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Moderate    Inter Info   
[137], [138]
D0679
 
Flurazepam
 
C21H23ClFN3O
 
3393 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0748
 
Halazepam
 
C17H12ClF3N2O
 
31640 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0750
 
Haloperidol
 
C21H23ClFNO2
 
3559 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0781
 
Hydroxyzine
 
C21H27ClN2O2
 
3658 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0782
 
Hyoscyamine
 
C17H23NO3
 
154417 
Moderate    Inter Info   
[117]
D0795
 
Imipramine
 
C19H24N2
 
3696 
Moderate    Inter Info   
[96], [97], [98], [99], [100], [101], [102]
D0890
 
Lamotrigine
 
C9H7Cl2N5
 
3878 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0923
 
Levorphanol
 
C17H23NO
 
5359272 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D0947
 
Loperamide
 
C29H33ClN2O2
 
3955 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0951
 
Lorazepam
 
C15H10Cl2N2O2
 
3958 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D0957
 
Loxapine
 
C18H18ClN3O
 
3964 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D0981
 
Mazindol
 
C16H13ClN2O
 
4020 
Moderate    Inter Info   
[121], [103], [122]
D0987
 
Meclizine
 
C25H27ClN2
 
4034 
Moderate    Inter Info   
[117]
D1001
 
Meperidine
 
C15H21NO2
 
4058 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1003
 
Mephenytoin
 
C12H14N2O2
 
4060 
Moderate    Inter Info   
[26], [13], [155], [156], [157]
D1014
 
Metaxalone
 
C12H15NO3
 
15459 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1017
 
Methadone
 
C21H27NO
 
4095 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1023
 
Methocarbamol
 
C11H15NO5
 
4107 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1039
 
Methylphenidate
 
C14H19NO2
 
4158 
Moderate    Inter Info   
[178], [179], [180]
D1053
 
Metyrosine
 
C10H13NO3
 
441350 
Moderate    Inter Info   
[181]
D1060
 
Midazolam
 
C18H13ClFN3
 
4192 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D1075
 
Mirtazapine
 
C17H19N3
 
4205 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1090
 
Morphine (liposomal)
 
C17H19NO3
 
5288826 
Moderate    Inter Info   
[80], [78], [76]
D1096
 
Nabilone
 
C24H36O3
 
5284592 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1100
 
Nalbuphine
 
C21H27NO4
 
5311304 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1158
 
Nortriptyline
 
C19H21N
 
4543 
Moderate    Inter Info   
[96], [97], [98], [99], [100], [101], [102]
D1166
 
Olanzapine
 
C17H20N4S
 
135398745 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1172
 
Olopatadine (nasal)
 
C21H23NO3
 
5281071 
Moderate    Inter Info   
[102], [120], [119]
D1198
 
Oxcarbazepine
 
C15H12N2O2
 
34312 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1203
 
Oxycodone
 
C18H21NO4
 
5284603 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1225
 
Paramethadione
 
C7H11NO3
 
8280 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1247
 
Pentazocine
 
C19H27NO
 
441278 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Moderate    Inter Info   
[137], [138]
D1263
 
Phenelzine
 
C8H12N2
 
3675 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1269
 
Phensuximide
 
C11H11NO2
 
6839 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1270
 
Phentermine
 
C10H15N
 
4771 
Moderate    Inter Info   
[121], [103], [122]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Moderate    Inter Info   
[26], [13], [155], [156], [157]
D1325
 
Pramipexole
 
C10H17N3S
 
119570 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1335
 
Pregabalin
 
C8H17NO2
 
5486971 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1346
 
Prochlorperazine
 
C20H24ClN3S
 
4917 
Moderate    Inter Info   
[137], [138]
D1347
 
Procyclidine
 
C19H29NO
 
4919 
Moderate    Inter Info   
[117]
D1351
 
Promazine
 
C17H20N2S
 
4926 
Moderate    Inter Info   
[137], [138]
D1355
 
Propiomazine
 
C20H24N2OS
 
4940 
Moderate    Inter Info   
[137], [138]
D1356
 
Propofol
 
C12H18O
 
4943 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1361
 
Protriptyline
 
C19H21N
 
4976 
Moderate    Inter Info   
[96], [97], [98], [99], [100], [101], [102]
D1413
 
Risperidone
 
C23H27FN4O2
 
5073 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1450
 
Scopolamine
 
C17H21NO4
 
3000322 
Moderate    Inter Info   
[117]
D1512
 
Sufentanil
 
C22H30N2O2S
 
41693 
Moderate    Inter Info   
[76], [77], [78], [79], [80], [81], [69], [82], [83]
D1547
 
Temazepam
 
C16H13ClN2O2
 
5391 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D1572
 
Thiethylperazine
 
C22H29N3S2
 
5440 
Moderate    Inter Info   
[137], [138]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Moderate    Inter Info   
[137], [138]
D1596
 
Tizanidine
 
C9H8ClN5S
 
5487 
Moderate    Inter Info   
[185]
D1604
 
Tolcapone
 
C14H11NO5
 
4659569 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1609
 
Topiramate
 
C12H21NO8S
 
5284627 
Moderate    Inter Info   
[186]
D1616
 
Tramadol
 
C16H25NO2
 
33741 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1620
 
Tranylcypromine
 
C9H11N
 
19493 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1624
 
Trazodone
 
C19H22ClN5O
 
5533 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1632
 
Triazolam
 
C17H12Cl2N4
 
5556 
Moderate    Inter Info   
[86], [87], [88], [89], [90], [91], [92]
D1641
 
Trihexyphenidyl
 
C20H31NO
 
5572 
Moderate    Inter Info   
[117]
D1642
 
Trimethadione
 
C6H9NO3
 
5576 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1647
 
Trimipramine
 
C20H26N2
 
5584 
Moderate    Inter Info   
[96], [97], [98], [99], [100], [101], [102]
D1649
 
Tripelennamine
 
C16H21N3
 
5587 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1650
 
Triprolidine
 
C19H22N2
 
5282443 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1656
 
Trospium
 
C25H30NO3+
 
5284632 
Moderate    Inter Info   
[117]
D1677
 
Valproic acid
 
C8H16O2
 
3121 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1726
 
Ziprasidone
 
C21H21ClN4OS
 
60854 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1728
 
Zolmitriptan
 
C16H21N3O2
 
60857 
Moderate    Inter Info   
[102], [118], [119], [13], [120]
D1729
 
Zolpidem
 
C19H21N3O
 
5732 
Moderate    Inter Info   
[26], [13], [118]
   Additive hypotensive effects Drug Num:  54
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0036
 
Alfuzosin
 
C19H27N5O4
 
2092 
Moderate    Inter Info   
[84], [85]
D0058
 
Amiloride
 
C6H8ClN7O
 
16231 
Moderate    Inter Info   
[93], [94], [95]
D0117
 
Atenolol
 
C14H22N2O3
 
2249 
Moderate    Inter Info   
[93], [94], [95]
D0156
 
Benazepril
 
C24H28N2O5
 
5362124 
Moderate    Inter Info   
[93], [94], [95]
D0158
 
Bendroflumethiazide
 
C15H14F3N3O4S2
 
2315 
Moderate    Inter Info   
[93], [94], [95]
D0166
 
Benzthiazide
 
C15H14ClN3O4S3
 
2343 
Moderate    Inter Info   
[93], [94], [95]
D0173
 
Betaxolol
 
C18H29NO3
 
2369 
Moderate    Inter Info   
[93], [94], [95]
D0217
 
Bumetanide
 
C17H20N2O5S
 
2471 
Moderate    Inter Info   
[93], [94], [95]
D0321
 
Chlorothiazide
 
C7H6ClN3O4S2
 
2720 
Moderate    Inter Info   
[93], [94], [95]
D0326
 
Chlorthalidone
 
C14H11ClN2O4S
 
2732 
Moderate    Inter Info   
[93], [94], [95]
D0363
 
Clonidine
 
C9H9Cl2N3
 
2803 
Moderate    Inter Info   
[93], [94], [95]
D0524
 
Doxazosin
 
C23H25N5O5
 
3157 
Moderate    Inter Info   
[84], [85]
D0585
 
Eplerenone
 
C24H30O6
 
443872 
Moderate    Inter Info   
[93], [94], [95]
D0602
 
Esmolol
 
C16H25NO4
 
59768 
Moderate    Inter Info   
[93], [94], [95]
D0010
 
Acebutolol
 
C18H28N2O4
 
1978 
Moderate    Inter Info   
[93], [94], [95]
D0128
 
Avanafil
 
C23H26ClN7O3
 
9869929 
Moderate    Inter Info   
[13], [150], [151], [152], [153]
D0138
 
Azilsartan medoxomil
 
C30H24N4O8
 
135409642 
Moderate    Inter Info   
[93], [94], [95]
D0170
 
Bepridil
 
C24H34N2O
 
2351 
Moderate    Inter Info   
[93], [94], [95]
D0267
 
Carvedilol
 
C24H26N2O4
 
2585 
Moderate    Inter Info   
[93], [94], [95]
D0352
 
Clevidipine
 
C21H23Cl2NO6
 
153994 
Moderate    Inter Info   
[93], [94], [95]
D0613
 
Etacrynic acid
 
C13H12Cl2O4
 
3278 
Moderate    Inter Info   
[93], [94], [95]
D0745
 
Guanfacine
 
C9H9Cl2N3O
 
3519 
Moderate    Inter Info   
[93], [94], [95]
D0771
 
Hydrochlorothiazide
 
C7H8ClN3O4S2
 
3639 
Moderate    Inter Info   
[93], [94], [95]
D0911
 
Levamlodipine
 
C20H25ClN2O5
 
9822750 
Moderate    Inter Info   
[93], [94], [95]
D1098
 
Nadolol
 
C17H27NO4
 
39147 
Moderate    Inter Info   
[93], [94], [95]
D1114
 
Nebivolol
 
C22H25F2NO4
 
71301 
Moderate    Inter Info   
[93], [94], [95]
D1293
 
Pindolol
 
C14H20N2O2
 
4828 
Moderate    Inter Info   
[93], [94], [95]
D1311
 
Polythiazide
 
C11H13ClF3N3O4S3
 
4870 
Moderate    Inter Info   
[93], [94], [95]
D1466
 
Silodosin
 
C25H32F3N3O4
 
5312125 
Moderate    Inter Info   
[84], [85]
D1545
 
Telmisartan
 
C33H30N4O2
 
65999 
Moderate    Inter Info   
[93], [94], [95]
D1552
 
Terazosin
 
C19H25N5O4
 
5401 
Moderate    Inter Info   
[84], [85]
D1633
 
Trichlormethiazide
 
C8H8Cl3N3O4S2
 
5560 
Moderate    Inter Info   
[93], [94], [95]
D0644
 
Fenoldopam
 
C16H16ClNO3
 
3341 
Moderate    Inter Info   
[93], [94], [95]
D0704
 
Furosemide
 
C12H11ClN2O5S
 
3440 
Moderate    Inter Info   
[93], [94], [95]
D0742
 
Guanabenz
 
C8H8Cl2N4
 
5702063 
Moderate    Inter Info   
[93], [94], [95]
D0743
 
Guanadrel
 
C10H19N3O2
 
38521 
Moderate    Inter Info   
[93], [94], [95]
D0775
 
Hydroflumethiazide
 
C8H8F3N3O4S2
 
3647 
Moderate    Inter Info   
[93], [94], [95]
D0798
 
Indapamide
 
C16H16ClN3O3S
 
3702 
Moderate    Inter Info   
[93], [94], [95]
D0884
 
Labetalol
 
C19H24N2O3
 
3869 
Moderate    Inter Info   
[93], [94], [95]
D1048
 
Metolazone
 
C16H16ClN3O3S
 
4170 
Moderate    Inter Info   
[93], [94], [95]
D1049
 
Metoprolol
 
C15H25NO3
 
4171 
Moderate    Inter Info   
[93], [94], [95]
D1138
 
Nimodipine
 
C21H26N2O7
 
4497 
Moderate    Inter Info   
[93], [94], [95]
D1331
 
Prazosin
 
C19H21N5O4
 
4893 
Moderate    Inter Info   
[84], [85]
D1357
 
Propranolol
 
C16H21NO2
 
4946 
Moderate    Inter Info   
[93], [94], [95]
D1393
 
Reserpine
 
C33H40N2O9
 
5770 
Moderate    Inter Info   
[93], [94], [95]
D1465
 
Sildenafil
 
C22H30N6O4S
 
135398744 
Moderate    Inter Info   
[13], [150], [151], [152], [153]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Moderate    Inter Info   
[93], [94], [95]
D1501
 
Spironolactone
 
C24H32O4S
 
5833 
Moderate    Inter Info   
[93], [94], [95]
D1527
 
Tadalafil
 
C22H19N3O4
 
110635 
Moderate    Inter Info   
[13], [150], [151], [152], [153]
D1534
 
Tamsulosin
 
C20H28N2O5S
 
129211 
Moderate    Inter Info   
[84], [85]
D1585
 
Timolol
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[93], [94], [95]
D1611
 
Torasemide
 
C16H20N4O3S
 
41781 
Moderate    Inter Info   
[93], [94], [95]
D1631
 
Triamterene
 
C12H11N7
 
5546 
Moderate    Inter Info   
[93], [94], [95]
D1682
 
Vardenafil
 
C23H32N6O4S
 
135400189 
Moderate    Inter Info   
[13], [150], [151], [152], [153]
   Increased risk of bleeding Drug Num:  3
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0481
 
Dicoumarol
 
C19H12O6
 
54676038 
Moderate    Inter Info   
[13], [142], [143]
D0087
 
Anisindione
 
C16H12O3
 
2197 
Moderate    Inter Info   
[146], [25], [13], [142], [147], [143], [148], [149]
D1711
 
Warfarin
 
C19H16O4
 
54678486 
Moderate    Inter Info   
[146], [25], [13], [142], [147], [143], [148], [149]
   Increased risk of GI mucosal injury/bleeding risk Drug Num:  18
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0476
 
Diclofenac
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[141]
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Moderate    Inter Info   
[141]
D0786
 
Ibuprofen
 
C13H18O2
 
3672 
Moderate    Inter Info   
[141]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Moderate    Inter Info   
[141]
D0988
 
Meclofenamic acid
 
C14H11Cl2NO2
 
4037 
Moderate    Inter Info   
[141]
D1196
 
Oxaprozin
 
C18H15NO3
 
4614 
Moderate    Inter Info   
[141]
D1442
 
Salsalate
 
C14H10O5
 
5161 
Moderate    Inter Info   
[141]
D0624
 
Etodolac
 
C17H21NO3
 
3308 
Moderate    Inter Info   
[141]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Moderate    Inter Info   
[141]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[141]
D0800
 
Indomethacin
 
C19H16ClNO4
 
3715 
Moderate    Inter Info   
[141]
D0882
 
Ketorolac
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[141]
D0991
 
Mefenamic acid
 
C15H15NO2
 
4044 
Moderate    Inter Info   
[141]
D1097
 
Nabumetone
 
C15H16O2
 
4409 
Moderate    Inter Info   
[141]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Moderate    Inter Info   
[141]
D1300
 
Piroxicam
 
C15H13N3O4S
 
54676228 
Moderate    Inter Info   
[141]
D1520
 
Sulindac
 
C20H17FO3S
 
1548887 
Moderate    Inter Info   
[141]
D1606
 
Tolmetin
 
C15H15NO3
 
5509 
Moderate    Inter Info   
[141]
   Increased risk of hepatotoxicity Drug Num:  31
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0011
 
Acetaminophen
 
C8H9NO2
 
1983 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12]
D0900
 
Leflunomide
 
C12H9F3N2O2
 
3899 
Major    Inter Info   
[25], [59], [60]
D1073
 
Mipomersen
 
C230H324N67O122P19S19
 
118984467 
Major    Inter Info   
[62]
D1258
 
Pexidartinib
 
C20H15ClF3N5
 
25151352 
Major    Inter Info   
[64]
D1556
 
Teriflunomide
 
C12H9F3N2O2
 
54684141 
Major    Inter Info   
[25], [59], [60]
D0114
 
Asparaginase Escherichia coli
 
NA
 
NA
Moderate    Inter Info   
[106], [107], [108], [26], [13], [109], [110], [111], [112], [113], [114], [115], [116]
D0303
 
Cerivastatin
 
C26H34FNO5
 
446156 
Moderate    Inter Info   
[134], [135], [136]
D0357
 
Clofarabine
 
C10H11ClFN5O3
 
119182 
Moderate    Inter Info   
[139]
D0554
 
Efavirenz
 
C14H9ClF3NO2
 
64139 
Moderate    Inter Info   
[144], [145]
D0113
 
Asparaginase Erwinia chrysanthemi
 
NA
 
NA
Moderate    Inter Info   
[106], [107], [108], [26], [13], [109], [110], [111], [112], [113], [114], [115], [116]
D0120
 
Atorvastatin
 
C33H35FN2O5
 
60823 
Moderate    Inter Info   
[134], [135], [136]
D0149
 
Bedaquiline
 
C32H31BrN2O2
 
5388906 
Moderate    Inter Info   
[154]
D0232
 
Calaspargase pegol
 
NA
 
NA
Moderate    Inter Info   
[106], [107], [108], [26], [13], [109], [110], [111], [112], [113], [114], [115], [116]
D0686
 
Fluvastatin
 
C24H26FNO4
 
446155 
Moderate    Inter Info   
[134], [135], [136]
D0789
 
Idelalisib
 
C22H18FN7O
 
11625818 
Moderate    Inter Info   
[158]
D0878
 
Kava
 
C14H16O3
 
5281052 
Moderate    Inter Info   
[159], [160], [161], [162], [163], [164]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Moderate    Inter Info   
[167]
D1239
 
Peginterferon beta-1a
 
NA
 
NA
Moderate    Inter Info   
[168], [169], [170], [171]
D1301
 
Pitavastatin
 
C25H24FNO4
 
5282452 
Moderate    Inter Info   
[134], [135], [136]
D1389
 
Remdesivir
 
C27H35N6O8P
 
121304016 
Moderate    Inter Info   
[26], [13], [172], [173], [174]
D1430
 
Rosuvastatin
 
C22H28FN3O6S
 
446157 
Moderate    Inter Info   
[134], [135], [136]
D1615
 
Trabectedin
 
C39H43N3O11S
 
108150 
Moderate    Inter Info   
[13], [176]
D0826
 
Interferon beta-1a
 
NA
 
NA
Moderate    Inter Info   
[168], [169], [170], [171]
D0827
 
Interferon beta-1b
 
NA
 
NA
Moderate    Inter Info   
[168], [169], [170], [171]
D0956
 
Lovastatin
 
C24H36O5
 
53232 
Moderate    Inter Info   
[134], [135], [136]
D1025
 
Methotrexate
 
C20H22N8O5
 
126941 
Moderate    Inter Info   
[13], [177]
D1106
 
Naltrexone
 
C20H23NO4
 
5360515 
Moderate    Inter Info   
[182]
D1234
 
Pegaspargase
 
C14H19NO
 
436058 
Moderate    Inter Info   
[106], [107], [108], [26], [13], [109], [110], [111], [112], [113], [114], [115], [116]
D1329
 
Pravastatin
 
C23H36O7
 
54687 
Moderate    Inter Info   
[134], [135], [136]
D1473
 
Simvastatin
 
C25H38O5
 
54454 
Moderate    Inter Info   
[134], [135], [136]
D1589
 
Tioguanine
 
C5H5N5S
 
2723601 
Moderate    Inter Info   
[183], [184]
   Increased risk of hypoglycemia Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1015
 
Metformin
 
C4H11N5
 
4091 
Major    Inter Info   
[72], [73]
   Increased risk of prolong QT interval Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0535
 
Droperidol
 
C22H22FN3O2
 
3168 
Major    Inter Info   
[25], [26], [13], [27], [28], [29]
   Potentiated the pharmacological effects (Unspecific) Drug Num:  3
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0074
 
Amphetamine
 
C9H13N
 
3007 
Moderate    Inter Info   
[103], [104]
D0465
 
Dextroamphetamine
 
C9H13N
 
5826 
Moderate    Inter Info   
[103], [104]
D0937
 
Lisdexamfetamine
 
C15H25N3O
 
11597698 
Moderate    Inter Info   
[103], [104]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  3
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0018
 
Acitretin
 
C21H26O3
 
5284513 
Major    Inter Info   
[13], [14]
D0509
 
Disulfiram
 
C10H20N2S4
 
3117 
Major    Inter Info   
[22], [23], [24]
D0562
 
Eluxadoline
 
C32H35N5O5
 
11250029 
Major    Inter Info   
[55]
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113 Product Information. Elspar (asparaginase). Merck & Co, Inc, West Point, PA.
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115 Product Information. Oncaspar (pegaspargase). Rhone-Poulenc Rorer, Collegeville, PA.
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120 Product Information. Fycompa (perampanel). Eisai Inc, Teaneck, NJ.
121 Product Information. Suprenza (phentermine). Akrimax Pharmaceuticals, Cranford, NJ.
122 Product Information. Didrex (benzphetamine) Pharmacia and Upjohn, Kalamazoo, MI.
123 Product Information. Alphagan (brimonidine ophthalmic). Allergan Inc, Irvine, CA.
124 Product Information. Mirvaso (brimonidine topical). Galderma Laboratories Inc, Cranbury, NJ.
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135 Product Information. Lipitor (atorvastatin). Parke-Davis, Morris Plains, NJ.
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139 Product Information. Clolar (clofarabine). sanofi-aventis, Bridgewater, NJ.
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141 Product Information. Motrin (ibuprofen). Pharmacia and Upjohn, Kalamazoo, MI.
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150 Product Information. Cialis (tadalafil). Lilly, Eli and Company, Indianapolis, IN.
151 Product Information. Levitra (vardenafil). Bayer, West Haven, CT.
152 Product Information. Stendra (avanafil). Vivus Inc, Mountain View, CA.
153 Product Information. Viagra (sildenafil). Pfizer US Pharmaceuticals, New York, NY.
154 Product Information. Sirturo (bedaquiline). Janssen Pharmaceuticals, Titusville, NJ.
155 Product Information. Dilantin (phenytoin). Parke-Davis, Morris Plains, NJ.
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165 Product Information. Ketalar (ketamine). JHP Pharmaceuticals, Saddle River, NJ.
166 Product Information. Dayvigo (lemborexant). Eisai Inc, Woodcliff Lake, NJ.
167 Product Information. Savella (milnacipran). Forest Pharmaceuticals, St. Louis, MO.
168 Product Information. Avonex (interferon beta-1a). Biogen, Cambridge, MA.
169 Product Information. Betaseron (interferon beta-1b). Berlex, Richmond, CA.
170 Product Information. Plegridy (peginterferon beta-1a). Biogen Idec Inc, Cambridge, MA.
171 Product Information. Rebif (interferon beta-1a). Serono Laboratories Inc, Norwell, MA.
172 European Medicines Agency "Summary on compassionate use. Remdesivir Gilead.".
173 Gilead Sciences, Inc "About Remdesivir.".
174 US Food and Drug Administration "Fact sheet for health care providers emergency use authorization (EUA) of remdesivir (GS-5734TM)".
175 Product Information. Tindamax (tinidazole). Presutti Laboratories Inc, Arlington Heights, IL.
176 Product Information. Yondelis (trabectedin). Janssen Pharmaceuticals, Titusville, NJ.
177 Product Information. Methotrexate (methotrexate). Lederle Laboratories, Wayne, NJ.
178 Product Information. Metadate CD Capsules (methylphenidate) Celltech Pharmaceuticals, Inc, Applegate, WI.
179 Product Information. Concerta (methylphenidate). Alza, Palo Alto, CA.
180 Product Information. Ritalin LA (methylphenidate). Quality Care Products/Lake Erie Medical , Temperance, MI.
181 Product Information. Demser (metyrosine). Merck &amp Co, Inc, West Point, PA.
182 Product Information. ReVia (naltrexone). DuPont Pharmaceuticals, Wilmington, DE.
183 Product Information. Aubagio (teriflunomide). Genzyme Corporation, Cambridge, MA.
184 Product Information. Tabloid (thioguanine). Prasco Laboratories, Cincinnati, OH.
185 Product Information. Zanaflex (tizanidine). Acorda Therapeutics, Hawthorne, NY.
186 Product Information. Topamax (topiramate). Ortho Pharmaceutical Corporation, Raritan, NJ.
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191 Product Information. Ziagen (abacavir). Glaxo Wellcome, Research Triangle Pk, NC.
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195 Product Information. Nizoral (ketoconazole). Janssen Pharmaceutica, Titusville, NJ.