Drug General Information (ID: DDILB7FDAR)
Drug Name			Methylphenidate		Drug Info		Ethanol		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Cns Stimulants				Analgesics
Structure

Mechanism of Methylphenidate-Ethanol Interaction (Severity Level: Moderate)
Additive CNS depression effects Click to Show/Hide Mechanism Graph
Drug Name		Methylphenidate				Ethanol
Mechanism		CNS depression effects				CNS depression effects
Key Mechanism Factor 1
		Factor Name		CNS depression effects
		Factor Description		CNS depressants are drugs that inhibit or suppress brain activity and can reduce mental and physical processes. Excessive CNS depression can lead to decreased heart rate, slow breathing (less than 10 breaths per minute), extreme confusion or loss of memory, nausea and vomiting, poor judgment, blue lips or fingertips, irritability and aggression, and clammy or cold skin.
Mechanism Description		Additive CNS depression effects by the combination of Methylphenidate and Ethanol

Recommended Action
Management		Patients treated with methylphenidate should be advised to avoid alcohol or medications that contain alcohol.

References
1	Product Information. Metadate CD Capsules (methylphenidate) Celltech Pharmaceuticals, Inc, Applegate, WI.
2	Product Information. Concerta (methylphenidate). Alza, Palo Alto, CA.
3	Product Information. Ritalin LA (methylphenidate). Quality Care Products/Lake Erie Medical , Temperance, MI.