Drug General Information (ID: DDI54BVNQZ)
  Drug Name Ethanol Drug Info Dextroamphetamine Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Analgesics Cns Stimulants
  Structure

 Mechanism of Ethanol-Dextroamphetamine Interaction (Severity Level: Moderate)
     Potentiated the pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Ethanol Dextroamphetamine
      Mechanism Potentiate the cardiovascular effects of amphetamines Amphetamines
      Key Mechanism Factor 1
Factor Name Pharmacodynamics
Factor Description Enhanced pharmacological effects leading to increased adverse reactions.
      Mechanism Description
  • Potentiate the pharmacologic effects by the combination of Ethanol and Dextroamphetamine 

Recommended Action
      Management Concomitant use of amphetamines and ethanol should be avoided if possible, especially in patients with a history of heart disease.

References
1 Mendelson J, Jones RT, Upton R, Jacob P 3rd "Methamphetamine and ethanol interactions in humans." Clin Pharmacol Ther 57 (1995): 559-68. [PMID: 7768079]
2 Jiao X, Velez S, Ringstad J, Eyma V, Miller D, Bleiberg M "Myocardial infarction associated with Adderall XR and alcohol use in a young man." J Am Board Fam Med 22 (2009): 197-201