Drug General Information (ID: DDIBGDF5Q0)
  Drug Name Norethisterone Drug Info Ethanol Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Contraceptive Agents Analgesics
  Structure

 Mechanism of Norethisterone-Ethanol Interaction (Severity Level: Minor)
     Decreased metabolism (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Norethisterone Ethanol
      Mechanism Inhibition metabolism of ethanol Ethanol
      Key Mechanism Factor 1
Factor Name Pharmacokinetics
Factor Description Alters the metabolism of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
      Mechanism Description
  • Decreased metabolism of Ethanol caused by Norethisterone 

References
1 Bailey DG, Arnold JMO, Spence JD "Grapefruit juice and drugs - how significant is the interaction." Clin Pharmacokinet 26 (1994): 91-8. [PMID: 8162660]
2 Gunston GD, Mehta U "Potentially serious drug interactions with grapefruit juice." S Afr Med J 90 (2000): 41. [PMID: 10721388]
3 Hobbes J, Boutagy J, Shenfield GM "Interactions between ethanol and oral contraceptive steroids." Clin Pharmacol Ther 38 (1985): 371-80. [PMID: 4042520]