Drug General Information (ID: DDIQ4KLV1U)
Drug Name			Dextromethorphan		Drug Info		Ethanol		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Analgesics				Analgesics
Structure

Mechanism of Dextromethorphan-Ethanol Interaction (Severity Level: Moderate)
Additive CNS depression effects Click to Show/Hide Mechanism Graph
Drug Name		Dextromethorphan				Ethanol
Mechanism		CNS depression effects				CNS depression effects
Key Mechanism Factor 1
		Factor Name		CNS depression effects
		Factor Description		CNS depressants are drugs that inhibit or suppress brain activity and can reduce mental and physical processes. Excessive CNS depression can lead to decreased heart rate, slow breathing (less than 10 breaths per minute), extreme confusion or loss of memory, nausea and vomiting, poor judgment, blue lips or fingertips, irritability and aggression, and clammy or cold skin.
Mechanism Description		Additive CNS depression effects by the combination of Dextromethorphan and Ethanol

Recommended Action
Management		Patients should be cautioned about the concomitant ingestion of dextromethorphan and ethanol. Consumption of large doses of either substance should be avoided.

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Cerner Multum, Inc. "Australian Product Information.".
3	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA.".