Drug General Information (ID: DDISA1GOZC)
Drug Name			Acitretin		Drug Info		Ethanol		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Keratolytic Agents				Analgesics
Structure

Mechanism of Acitretin-Ethanol Interaction (Severity Level: Major)
Increased risk of other adverse reactions (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Acitretin				Ethanol
Mechanism		Acitretin				Increase the duration of teratogenic potential of acitretin in female patients
Key Mechanism Factor 1
		Factor Name		Adverse reactions
		Factor Description		An adverse reaction is an unexpected negative reaction to a medication or treatment that happens even when it's used correctly.
Mechanism Description		Increased risk of adverse reactions by the combination of Acitretin and Ethanol

Recommended Action
Management		Female patients should be warned that ethanol is contraindicated during active treatment with acitretin and for two months after cessation of therapy.

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Product Information. Soriatane (acitretin). Roche Laboratories, Nutley, NJ.