Details of Drug

Drug General Information (ID: D1511)
Drug Name	Sucralfate
Drug Type	Small molecule
Drug Synonymous	SUL; Ulcerlmin; Sucralfate, Chugai; Sucralfate, Scios Nova Click to Show/Hide
Disease Class	ED80: Acne vulgaris
Therapeutic Class	Gi Agents
Structure
Structure	3D Structure		2D Structure
Formula	C12H54Al9O55S8
InChI	1S/C12H22O35S8.9Al.20H2O/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;;;;;;;;;201H2/q;;8+1;;;;;;;;;;;;;;;;;;;;/p-8/t4-,5-,6-,7-,8+,9-,10+,11-,12+;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1............................./s1
InChIKey	YZPQNHUVIVIUCT-JTJNLBSYSA-F
Canonical SMILES	C(C1C(C(C(C(O1)OC2(C(C(C(O2)COS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al])COS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al].O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.[Al]
External Link
	Pubchem ID	121494085
	CAS Number	54182-58-0
	TTD ID	D06ULU

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption BM003 Complex formation BM004 Adsorption BM009 Altered absorption (Unspecific)
Relation Graph

Full list of drugs interacting with Sucralfate
Affected gastrointestinal absorption
	Complex formation					Drug Num: 59
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0181		Bictegravir	C21H18F3N3O5	90311989	Major		Inter Info	[1], [2], [3]
D0515		Dolutegravir	C20H19F2N3O5	54726191	Major		Inter Info	[4]
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[7]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[8], [9], [10]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D1283		Phenytoin	C15H12N2O2	1775	Moderate		Inter Info	[9], [10], [43]
D0034		Alendronic acid	C4H13NO7P2	2088	Moderate		Inter Info	[44], [45], [46]
D0144		Baloxavir marboxil	C27H23F2N3O7S	124081896	Moderate		Inter Info	[48]
D0310		Chenodeoxycholic acid	C24H40O4	10133	Moderate		Inter Info	[49]
D0330		Cholic Acid	C24H40O5	221493	Moderate		Inter Info	[50]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0432		Deferasirox	C21H15N3O4	214348	Moderate		Inter Info	[51]
D0433		Deferiprone	C7H9NO2	2972	Moderate		Inter Info	[1], [2], [52]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0490		Digitoxin	C41H64O13	441207	Moderate		Inter Info	[9], [10], [53]
D0491		Digoxin	C41H64O14	2724385	Moderate		Inter Info	[9], [10], [53]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[2], [54]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0783		Ibandronate	C9H23NO7P2	60852	Moderate		Inter Info	[55], [56], [44], [45], [57], [46]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D1003		Mephenytoin	C12H14N2O2	4060	Moderate		Inter Info	[9], [10], [43]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[8], [9], [10]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[58]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D1175		Omadacycline	C29H40N4O7	54697325	Moderate		Inter Info	[8], [9], [10]
D1245		Penicillamine	C5H11NO2S	5852	Moderate		Inter Info	[59], [60], [61], [62], [63], [64], [65], [32]
D1369		Quinapril	C25H30N2O5	54892	Moderate		Inter Info	[2], [54]
D1412		Risedronic acid	C7H11NO7P2	5245	Moderate		Inter Info	[44], [45], [46]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[8], [9], [10]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[8], [9], [10]
D1584		Tiludronic acid	C7H9ClO6P2S	60937	Moderate		Inter Info	[45], [66], [46]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0117		Atenolol	C14H22N2O3	2249	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0173		Betaxolol	C18H29NO3	2369	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0934		Liothyronine	C15H12I3NO4	5920	Minor		Inter Info	[74], [75]
D1049		Metoprolol	C15H25NO3	4171	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0010		Acebutolol	C18H28N2O4	1978	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0188		Bisoprolol	C18H31NO4	2405	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0265		Carteolol	C16H24N2O3	2583	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0267		Carvedilol	C24H26N2O4	2585	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0884		Labetalol	C19H24N2O3	3869	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D0925		Levothyroxine	C15H11I4NO4	5819	Minor		Inter Info	[74], [75]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Minor		Inter Info	[74], [75]
D1098		Nadolol	C17H27NO4	39147	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D1109		Naproxen	C14H14O3	156391	Minor		Inter Info	[89], [1], [2], [90]
D1114		Nebivolol	C22H25F2NO4	71301	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D1244		Penbutolol	C18H29NO2	37464	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D1293		Pindolol	C14H20N2O2	4828	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D1357		Propranolol	C16H21NO2	4946	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D1498		Sotalol	C12H20N2O3S	5253	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
D1577		Thyroid, porcine	NA	NA	Minor		Inter Info	[74], [75], [91]
D1585		Timolol	C13H24N4O3S	33624	Minor		Inter Info	[67], [68], [69], [70], [71], [72], [73]
	Adsorption					Drug Num: 15
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0037		Alimemazine	C18H22N2S	5574	Minor		Inter Info	[76], [77], [78]
D0324		Chlorpromazine	C17H19ClN2S	2726	Minor		Inter Info	[76], [77], [79], [80], [78]
D0678		Fluphenazine	C22H26F3N3OS	3372	Minor		Inter Info	[76], [77], [79], [80], [78]
D1010		Mesoridazine	C21H26N2OS2	4078	Minor		Inter Info	[76], [77], [79], [80], [78]
D1019		Methdilazine	C18H20N2S	14677	Minor		Inter Info	[76], [77], [79], [80], [78]
D1026		Methotrimeprazine	C19H24N2OS	72287	Minor		Inter Info	[76], [77], [79], [80], [78]
D1257		Perphenazine	C21H26ClN3OS	4748	Minor		Inter Info	[76], [77], [79], [80], [78]
D1346		Prochlorperazine	C20H24ClN3S	4917	Minor		Inter Info	[76], [77], [79], [80], [78]
D1351		Promazine	C17H20N2S	4926	Minor		Inter Info	[76], [77], [79], [80], [78]
D1352		Promethazine	C17H20N2S	4927	Minor		Inter Info	[76], [77], [79], [80], [78]
D1355		Propiomazine	C20H24N2OS	4940	Minor		Inter Info	[76], [77], [79], [80], [78]
D1572		Thiethylperazine	C22H29N3S2	5440	Minor		Inter Info	[76], [77], [79], [80], [78]
D1574		Thioridazine	C21H26N2S2	5452	Minor		Inter Info	[76], [77], [79], [80], [78]
D1637		Trifluoperazine	C21H24F3N3S	5566	Minor		Inter Info	[76], [77], [79], [80], [78]
D1638		Triflupromazine	C18H19F3N2S	5568	Minor		Inter Info	[76], [77], [79], [80], [78]
	Altered absorption (Unspecific)					Drug Num: 8
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0527		Doxercalciferol	C28H44O2	5281107	Major		Inter Info	[2], [5]
D1226		Paricalcitol	C27H44O3	5281104	Major		Inter Info	[2], [5]
D0111		Ascorbic acid	C6H8O6	54670067	Moderate		Inter Info	[2], [6]
D0040		Allopurinol	C5H4N4O	135401907	Moderate		Inter Info	[1], [2], [47]
D0476		Diclofenac	C14H11Cl2NO2	3033	Minor		Inter Info	[81]
D0489		Diflunisal	C13H8F2O3	3059	Minor		Inter Info	[67], [82], [83]
D0858		Isoniazid	C6H7N3O	3767	Minor		Inter Info	[84], [85]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Minor		Inter Info	[86], [87], [88]

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