Drug General Information (ID: DDIGCX2D40)
Drug Name			Sucralfate		Drug Info		Doxercalciferol		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Gi Agents				Vitamins
Structure

Mechanism of Sucralfate-Doxercalciferol Interaction (Severity Level: Major)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Sucralfate				Doxercalciferol
Mechanism		Absorption increased by vitamin D analogs				Vitamin D analogs
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Sucralfate caused by Doxercalciferol

Recommended Action
Management		Aluminum-containing preparations (e.g., antacids, phosphate binders) should not be administered chronically with vitamin D analogs.

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Product Information. Zemplar (paricalcitol). Abbott Pharmaceutical, Abbott Park, IL.