Details of Drug

Drug General Information (ID: D0483)
Drug Name	Didanosine
Drug Type	Small molecule
Drug Synonymous	didanosine; 69655-05-6; DIDEOXYINOSINE; Videx; Videx EC; Inosine, 2',3'-dideoxy-; ddIno; Didanosina; Didanosinum; DDI; BMY-40900; UNII-K3GDH6OH08; K3GDH6OH08; Didanosinum [INN-Latin]; Didanosina [INN-Spanish]; CHEBI:490877; 9-(2,3-Dideoxy-beta-D-ribofuranosyl)-6-oxopurine; NSC 612049; 9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; 9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE; NCGC00159514-02; NCGC00090691-03; DRG-0016; BMY 40900; DSSTox_CID_2927 Click to Show/Hide
Disease Class	1C60-1C62: Human immunodeficiency virus disease
Therapeutic Class	Anti-Hiv Agents
Structure
Structure	3D Structure		2D Structure
Formula	C10H12N4O3
InChI	1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1
InChIKey	BXZVVICBKDXVGW-NKWVEPMBSA-N
Canonical SMILES	C1CC(OC1CO)N2C=NC3=C2N=CNC3=O
External Link
	Pubchem ID	135398739
	CAS Number	69655-05-6
	CHEBI ID	490877
	TTD ID	D06FDR
	VARIDT ID	DR01175

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM002 Affected cellular transport AM004 Affected intra/extra-hepatic metabolism AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM001 Altered gastrointestinal dynamics BM003 Complex formation BM005 Altered gastric pH BM009 Altered absorption (Unspecific) BM010 Transporter inhibition BM017 CYP450 enzyme inhibition BM018 Non-CYP450 enzyme inhibition BM028 Competitive inhibition of renal tubular secretion BM029 Altered urine pH BM055 Increased risk of hepatotoxicity BM074 Increased risk of peripheral neuropathy BM107 Attenuated pharmacological effects (Unspecific) BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Didanosine
Affected gastrointestinal absorption
	Altered gastrointestinal dynamics					Drug Num: 15
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0045		Alprazolam	C17H13ClN4	2118	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0317		Chlordiazepoxide	C16H14ClN3O	2712	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0356		Clobazam	C16H13ClN2O2	2789	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0365		Clorazepic acid	C16H11ClN2O3	2809	Minor		Inter Info	[160], [161], [164]
D0473		Diazepam	C16H13ClN2O	3016	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0362		Clonazepam	C15H10ClN3O3	2802	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0604		Estazolam	C16H11ClN4	3261	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D1367		Quazepam	C17H11ClF4N2S	4999	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0679		Flurazepam	C21H23ClFN3O	3393	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0748		Halazepam	C17H12ClF3N2O	31640	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D0951		Lorazepam	C15H10Cl2N2O2	3958	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D1060		Midazolam	C18H13ClFN3	4192	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D1197		Oxazepam	C15H11ClN2O2	4616	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D1547		Temazepam	C16H13ClN2O2	5391	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
D1632		Triazolam	C17H12Cl2N4	5556	Minor		Inter Info	[159], [160], [161], [162], [163], [164], [165], [166], [167]
	Complex formation					Drug Num: 29
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0515		Dolutegravir	C20H19F2N3O5	54726191	Major		Inter Info	[5], [2]
D0034		Alendronic acid	C4H13NO7P2	2088	Moderate		Inter Info	[27], [28], [29]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[47], [48], [49], [50], [51], [52], [2], [53], [54], [55]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[47], [56], [48], [49], [57], [58], [50], [59], [52], [2], [53], [54], [60], [55]
D0433		Deferiprone	C7H9NO2	2972	Moderate		Inter Info	[84]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[47], [56], [48], [49], [57], [58], [50], [59], [52], [2], [53], [54], [60], [55]
D0561		Eltrombopag	C25H22N4O4	135449332	Moderate		Inter Info	[3], [85]
D0563		Elvitegravir	C23H23ClFNO5	5277135	Moderate		Inter Info	[16], [3]
D0623		Etidronic acid	C2H8O7P2	3305	Moderate		Inter Info	[28], [86], [29]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[47], [48], [90], [49], [50], [91], [2], [54], [55]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[47], [48], [49], [50], [92], [2], [54], [55]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[96], [47], [48], [49], [97], [50], [2], [54], [98], [60], [99], [55]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Moderate		Inter Info	[100], [8], [16], [3], [101], [102], [103], [104], [105], [106], [107]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[47], [48], [49], [57], [50], [2], [54], [60], [108], [55]
D0948		Lopinavir	C37H48N4O5	92727	Moderate		Inter Info	[8], [109], [110]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[117], [47], [48], [49], [118], [119], [120], [50], [121], [2], [54], [60], [55]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[122], [47], [123], [56], [48], [49], [57], [50], [124], [2], [54], [60], [55]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[134], [48], [49], [57], [50], [2], [135], [54], [55]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[103], [104], [105]
D1584		Tiludronic acid	C7H9ClO6P2S	60937	Moderate		Inter Info	[28], [86], [29]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[47], [139], [48], [49], [57], [50], [140], [2], [54], [60], [55]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[47], [48], [49], [50], [142], [2], [54], [55]
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[100], [8], [16], [3], [101], [102], [103], [104], [105], [106], [107]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[100], [8], [16], [3], [101], [102], [103], [104], [105], [106], [107]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[47], [48], [49], [50], [143], [2], [54], [144], [55]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[47], [48], [49], [50], [52], [145], [2], [53], [54], [55]
D1245		Penicillamine	C5H11NO2S	5852	Moderate		Inter Info	[149], [150], [151], [152], [153], [154], [155], [156]
D1412		Risedronic acid	C7H11NO7P2	5245	Moderate		Inter Info	[27], [28], [29]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[48], [49], [50], [157], [54], [158], [55]
	Altered gastric pH					Drug Num: 29
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0074		Amphetamine	C9H13N	3007	Moderate		Inter Info	[30]
D0080		Amprenavir	C25H35N3O6S	65016	Moderate		Inter Info	[31], [32]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[30]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[16], [66]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[67], [68]
D0278		Cefditoren	C19H18N6O5S3	9870843	Moderate		Inter Info	[72]
D0288		Cefpodoxime	C15H17N5O6S2	6335986	Moderate		Inter Info	[67], [73], [74], [68]
D0297		Cefuroxime	C16H16N4O8S	5479529	Moderate		Inter Info	[67], [73], [74], [68]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[83]
D0465		Dextroamphetamine	C9H13N	5826	Moderate		Inter Info	[30]
D0867		Itraconazole	C35H38Cl2N8O4	55283	Moderate		Inter Info	[94], [95]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Moderate		Inter Info	[94], [95]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[30]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[111], [30], [112]
D1095		Mycophenolic acid	C17H20O6	446541	Moderate		Inter Info	[113], [114], [115], [116]
D1400		Rifampicin	C43H58N4O12	135398735	Moderate		Inter Info	[133]
D0799		Indinavir	C36H47N5O4	5362440	Moderate		Inter Info	[2]
D1094		Mycophenolate mofetil	C23H31NO7	5281078	Moderate		Inter Info	[113], [114], [115], [116]
D0156		Benazepril	C24H28N2O5	5362124	Minor		Inter Info	[168]
D0254		Captopril	C9H15NO3S	44093	Minor		Inter Info	[168]
D0695		Fosinopril	C30H46NO7P	55891	Minor		Inter Info	[168]
D0938		Lisinopril	C21H31N3O5	5362119	Minor		Inter Info	[168]
D1082		Moexipril	C27H34N2O7	91270	Minor		Inter Info	[168]
D1256		Perindopril	C19H32N2O5	107807	Minor		Inter Info	[168]
D1369		Quinapril	C25H30N2O5	54892	Minor		Inter Info	[168]
D1379		Ramipril	C23H32N2O5	5362129	Minor		Inter Info	[168]
D1381		Ranitidine	C13H22N4O3S	3001055	Minor		Inter Info	[169], [2]
D1382		Ranitidine (bismuth citrate)	C13H22N4O3S	3001055	Minor		Inter Info	[169], [2]
D1618		Trandolapril	C24H34N2O5	5484727	Minor		Inter Info	[168]
	Altered absorption (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0426		Darunavir	C27H37N3O7S	213039	Moderate		Inter Info	[78]
D1187		Orlistat	C29H53NO5	3034010	Moderate		Inter Info	[125]
D1119		Nelfinavir	C32H45N3O4S	64143	Moderate		Inter Info	[147]
Affected cellular transport
	Transporter inhibition					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1143		Nitisinone	C14H10F3NO5	115355	Moderate		Inter Info	[148]
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0375		Cobicistat	C40H53N7O5S2	25151504	Moderate		Inter Info	[16], [3], [75], [76], [77], [78], [79], [80], [81], [82]
	Non-CYP450 enzyme inhibition					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0040		Allopurinol	C5H4N4O	135401907	Major		Inter Info	[1], [2]
Affected excretion pathways
	Competitive inhibition of renal tubular secretion					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0710		Ganciclovir	C9H13N5O4	135398740	Moderate		Inter Info	[87], [88], [89]
D1676		Valganciclovir	C14H22N6O5	135413535	Moderate		Inter Info	[87], [88], [89]
	Altered urine pH					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[63], [64], [65]
D0331		Choline salicylate	C12H19NO4	54686350	Moderate		Inter Info	[63], [64], [65]
D1272		Phenyl salicylate	C13H10O3	8361	Moderate		Inter Info	[63], [64], [65]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[63], [64], [65]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[63], [64], [65]
Pharmacodynamic additive effects
	Increased risk of hepatotoxicity					Drug Num: 20
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0900		Leflunomide	C12H9F3N2O2	3899	Major		Inter Info	[8], [9], [10]
D0944		Lomitapide	C39H37F6N3O2	9853053	Major		Inter Info	[11]
D1073		Mipomersen	C230H324N67O122P19S19	118984467	Major		Inter Info	[12]
D1258		Pexidartinib	C20H15ClF3N5	25151352	Major		Inter Info	[13]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Major		Inter Info	[8], [9], [10]
D0114		Asparaginase Escherichia coli	NA	NA	Moderate		Inter Info	[33], [34], [35], [16], [3], [36], [37], [38], [39], [40], [41], [42], [43]
D0357		Clofarabine	C10H11ClFN5O3	119182	Moderate		Inter Info	[62]
D0113		Asparaginase Erwinia chrysanthemi	NA	NA	Moderate		Inter Info	[33], [34], [35], [16], [3], [36], [37], [38], [39], [40], [41], [42], [43]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Moderate		Inter Info	[69]
D0199		Brentuximab vedotin	NA	NA	Moderate		Inter Info	[70], [71]
D0232		Calaspargase pegol	NA	NA	Moderate		Inter Info	[33], [34], [35], [16], [3], [36], [37], [38], [39], [40], [41], [42], [43]
D0789		Idelalisib	C22H18FN7O	11625818	Moderate		Inter Info	[93]
D1239		Peginterferon beta-1a	NA	NA	Moderate		Inter Info	[126], [127], [128], [129]
D1389		Remdesivir	C27H35N6O8P	121304016	Moderate		Inter Info	[16], [3], [130], [131], [132]
D1615		Trabectedin	C39H43N3O11S	108150	Moderate		Inter Info	[3], [137]
D0554		Efavirenz	C14H9ClF3NO2	64139	Moderate		Inter Info	[138], [80]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[16], [3], [141]
D0826		Interferon beta-1a	NA	NA	Moderate		Inter Info	[126], [127], [128], [129]
D0827		Interferon beta-1b	NA	NA	Moderate		Inter Info	[126], [127], [128], [129]
D1106		Naltrexone	C20H23NO4	5360515	Moderate		Inter Info	[146]
	Increased risk of peripheral neuropathy					Drug Num: 69
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0023		Adalimumab	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0193		Bortezomib	C19H25BN4O4	387447	Moderate		Inter Info	[44], [45], [46]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[24], [25], [26]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[24], [25], [26]
D0344		Cisplatin	Cl2H6N2Pt	5702198	Moderate		Inter Info	[24], [25], [26]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[24], [25], [26]
D0126		Auranofin	C20H34AuO9PS	24199313	Moderate		Inter Info	[24], [25], [26]
D0127		Aurothioglucose	C6H11AuO5S	454937	Moderate		Inter Info	[24], [25], [26]
D0162		Benznidazole	C12H12N4O3	31593	Moderate		Inter Info	[24], [25], [26]
D0227		Cabazitaxel	C45H57NO14	9854073	Moderate		Inter Info	[24], [25], [26]
D0260		Carboplatin	C6H12N2O4Pt	426756	Moderate		Inter Info	[24], [25], [26]
D0261		Carfilzomib	C40H57N5O7	11556711	Moderate		Inter Info	[24], [25], [26]
D0304		Certolizumab pegol	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0380		Colchicine	C22H25NO6	6167	Moderate		Inter Info	[24], [25], [26]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Moderate		Inter Info	[24], [25], [26]
D0496		Diiodohydroxyquinoline	C9H5I2NO	3728	Moderate		Inter Info	[24], [25], [26]
D0501		Dinutuximab	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0511		Docetaxel	C43H53NO14	148124	Moderate		Inter Info	[24], [25], [26]
D0560		Elotuzumab	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0571		Enfortumab vedotin	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[24], [25], [26]
D0628		Etravirine	C20H15BrN6O	193962	Moderate		Inter Info	[24], [25], [26]
D0669		Fludarabine	C10H12FN5O4	657237	Moderate		Inter Info	[24], [25], [26]
D0686		Fluvastatin	C24H26FNO4	446155	Moderate		Inter Info	[24], [25], [26]
D0841		Ipilimumab	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[24], [25], [26]
D0873		Ixabepilone	C27H42N2O5S	6445540	Moderate		Inter Info	[24], [25], [26]
D0874		Ixazomib	C14H19BCl2N2O4	25183872	Moderate		Inter Info	[24], [25], [26]
D0918		Levodopa	C9H11NO4	6047	Moderate		Inter Info	[24], [25], [26]
D1051		Metronidazole	C6H9N3O3	4173	Moderate		Inter Info	[24], [25], [26]
D1113		Naxitamab	NA	NA	Moderate		Inter Info	[24], [25], [26]
D1118		Nelarabine	C11H15N5O5	3011155	Moderate		Inter Info	[24], [25], [26]
D1212		Paclitaxel	C47H51NO14	36314	Moderate		Inter Info	[24], [25], [26]
D1213		Paclitaxel (protein-bound)	C47H51NO14	36314	Moderate		Inter Info	[24], [25], [26]
D1301		Pitavastatin	C25H24FNO4	5282452	Moderate		Inter Info	[24], [25], [26]
D1306		Polatuzumab vedotin	NA	NA	Moderate		Inter Info	[24], [25], [26]
D1312		Pomalidomide	C13H11N3O4	134780	Moderate		Inter Info	[24], [25], [26]
D1313		Ponatinib	C29H27F3N6O	24826799	Moderate		Inter Info	[24], [25], [26]
D1430		Rosuvastatin	C22H28FN3O6S	446157	Moderate		Inter Info	[24], [25], [26]
D1452		Secnidazole	C7H11N3O3	71815	Moderate		Inter Info	[24], [25], [26]
D1479		Sodium aurothiomalate	C4H3AuNa2O4S	22318	Moderate		Inter Info	[24], [25], [26]
D1543		Telbivudine	C10H14N2O5	159269	Moderate		Inter Info	[24], [25], [26]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[44], [16], [3], [136]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[24], [25], [26]
D1599		Tocilizumab	NA	NA	Moderate		Inter Info	[24], [25], [26]
D1623		Trastuzumab emtansine	NA	NA	Moderate		Inter Info	[24], [25], [26]
D1715		Zalcitabine	C9H13N3O3	24066	Moderate		Inter Info	[44], [17]
D0509		Disulfiram	C10H20N2S4	3117	Moderate		Inter Info	[24], [25], [26]
D0614		Etanercept	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0616		Ethambutol	C10H24N2O2	14052	Moderate		Inter Info	[24], [25], [26]
D1731		Ethionamide	C8H10N2S	2761171	Moderate		Inter Info	[24], [25], [26]
D0627		Etoposide	C29H32O13	36462	Moderate		Inter Info	[24], [25], [26]
D0802		Infliximab	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0821		Interferon alfa-2a, Recombinant	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0822		Interferon alfa-2b	C16H17Cl3I2N3NaO5S	71306834	Moderate		Inter Info	[24], [25], [26]
D0824		Interferon alfa-n1	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0823		Interferon alfacon-1	NA	NA	Moderate		Inter Info	[24], [25], [26]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[24], [25], [26]
D0956		Lovastatin	C24H36O5	53232	Moderate		Inter Info	[24], [25], [26]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Moderate		Inter Info	[24], [25], [26]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[24], [25], [26]
D1237		Peginterferon alfa-2a	NA	NA	Moderate		Inter Info	[24], [25], [26]
D1329		Pravastatin	C23H36O7	54687	Moderate		Inter Info	[24], [25], [26]
D1473		Simvastatin	C25H38O5	54454	Moderate		Inter Info	[24], [25], [26]
D1551		Teniposide	C32H32O13S	452548	Moderate		Inter Info	[24], [25], [26]
D1698		Vincristine	C46H56N4O10	5978	Moderate		Inter Info	[24], [25], [26]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Moderate		Inter Info	[24], [25], [26]
D1700		Vinorelbine	C45H54N4O8	5311497	Moderate		Inter Info	[24], [25], [26]
D1714		Zafirlukast	C31H33N3O6S	5717	Moderate		Inter Info	[24], [25], [26]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0178		Bexarotene	C24H28O2	82146	Major		Inter Info	[3], [4]
D0780		Hydroxyurea	CH4N2O2	3657	Major		Inter Info	[2], [6], [7]
D1017		Methadone	C21H27NO	4095	Major		Inter Info	[14], [2], [15]
D1246		Pentamidine	C19H24N4O2	4735	Major		Inter Info	[16], [3], [17]
D1397		Ribavirin	C8H12N4O5	37542	Major		Inter Info	[18], [19], [20]
D1504		Stavudine	C10H12N2O4	18283	Major		Inter Info	[6], [21], [22], [23]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0348		Cladribine	C10H12ClN5O3	20279	Moderate		Inter Info	[3], [25], [61]

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