Drug General Information (ID: DDIVIO3UT1)
Drug Name			Nelfinavir		Drug Info		Didanosine		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Protease Inhibitors				Anti-Hiv Agents
Structure

Mechanism of Nelfinavir-Didanosine Interaction (Severity Level: Moderate)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Nelfinavir				Didanosine
Mechanism		Decrease absorption of delavirdine didanosine				Didanosine
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Didanosine caused by Nelfinavir

Recommended Action
Management		Nelfinavir should be taken with food at least two hours before or one hour after didanosine.

References
1	Product Information. Viracept (nelfinavir). Agouron Pharma Inc, La Jolla, CA.