Drug General Information (ID: D0049)
  Drug Name
Aluminum hydroxide
  Drug Type Small molecule
  Drug Synonymous
aluminum;trihydroxide; Dried aluminum hydroxide gel; Aluminium hydroxide gel, dried; aluminium trihydroxide; aluminum hyroxide; Hydroxyde d' aluminium; Dried aluminium hydroxide; Aluminium hydroxide, dried; Aluminum hydroxide gel, dried; CHEMBL1200706; DTXSID2036405; NIOSH/BD0708000; Di-mu-hydroxytetrahydroxydialuminum; AF-260; AKOS015904617; Aluminum, di-mu-hydroxytetrahydroxydi-; DB06723; BD07080000; Q407125; J-014205; UNII-F41V936QZM component WNROFYMDJYEPJX-UHFFFAOYSA-K
    Click to Show/Hide
  Therapeutic Class Antacids
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula AlH3O3
  InChI InChI=1S/Al.3H2O/h;3*1H2/q+3;;;/p-3
  InChIKey WNROFYMDJYEPJX-UHFFFAOYSA-K
  Canonical SMILES [OH-].[OH-].[OH-].[Al+3]
  External Link
Pubchem ID 10176082

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
AM005  Affected excretion pathways
AM007  Pharmacodynamic antagonistic effects
BM001  Altered gastrointestinal dynamics
BM003  Complex formation
BM004  Adsorption
BM005  Altered gastric pH
BM009  Altered absorption (Unspecific)
BM029  Altered urine pH
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Aluminum hydroxide
      Affected gastrointestinal absorption
   Altered gastrointestinal dynamics Drug Num:  13
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0045
 
Alprazolam
 
C17H13ClN4
 
2118 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D0317
 
Chlordiazepoxide
 
C16H14ClN3O
 
2712 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D0356
 
Clobazam
 
C16H13ClN2O2
 
2789 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D0362
 
Clonazepam
 
C15H10ClN3O3
 
2802 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D0473
 
Diazepam
 
C16H13ClN2O
 
3016 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D0604
 
Estazolam
 
C16H11ClN4
 
3261 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D0679
 
Flurazepam
 
C21H23ClFN3O
 
3393 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D0951
 
Lorazepam
 
C15H10Cl2N2O2
 
3958 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D1060
 
Midazolam
 
C18H13ClFN3
 
4192 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D1197
 
Oxazepam
 
C15H11ClN2O2
 
4616 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D1367
 
Quazepam
 
C17H11ClF4N2S
 
4999 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D1547
 
Temazepam
 
C16H13ClN2O2
 
5391 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
D1632
 
Triazolam
 
C17H12Cl2N4
 
5556 
Minor    Inter Info   
[175], [176], [177], [178], [179], [180], [181], [182], [183]
   Complex formation Drug Num:  67
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0181
 
Bictegravir
 
C21H18F3N3O5
 
90311989 
Major    Inter Info   
[1], [2], [3]
D0238
 
Calcium citrate
 
C12H10Ca3O14
 
13136 
Major    Inter Info   
[2]
D0515
 
Dolutegravir
 
C20H19F2N3O5
 
54726191 
Major    Inter Info   
[4]
D1231
 
Patiromer
 
NA
 
NA
Major    Inter Info   
[6], [7], [8]
D1319
 
Potassium citrate
 
C6H5K3O7
 
13344 
Major    Inter Info   
[2]
D1377
 
Raltegravir
 
C20H21FN6O5
 
54671008 
Major    Inter Info   
[9], [1], [2], [10], [11], [12], [13]
D1483
 
Sodium citrate
 
C6H5Na3O7
 
6224 
Major    Inter Info   
[2]
D1605
 
Tolevamer
 
C11H16O3S
 
58817179 
Major    Inter Info   
[6], [7], [8]
D0034
 
Alendronic acid
 
C4H13NO7P2
 
2088 
Moderate    Inter Info   
[26], [27], [28]
D0144
 
Baloxavir marboxil
 
C27H23F2N3O7S
 
124081896 
Moderate    Inter Info   
[31]
D0433
 
Deferiprone
 
C7H9NO2
 
2972 
Moderate    Inter Info   
[1], [2], [40]
D0438
 
Delafloxacin
 
C18H12ClF3N4O4
 
487101 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1175
 
Omadacycline
 
C29H40N4O7
 
54697325 
Moderate    Inter Info   
[23], [80], [81], [82], [83], [84], [85], [86], [87], [88], [62], [89], [72]
D1445
 
Sarecycline
 
C24H29N3O8
 
54681908 
Moderate    Inter Info   
[23], [80], [81], [82], [83], [84], [85], [86], [87], [88], [62], [89], [72]
D1577
 
Thyroid, porcine
 
NA
 
NA
Moderate    Inter Info   
[93], [94], [95]
D0139
 
Azithromycin
 
C38H72N2O12
 
447043 
Moderate    Inter Info   
[104]
D0271
 
Cefaclor
 
C15H14ClN3O4S
 
51039 
Moderate    Inter Info   
[107]
D0277
 
Cefdinir
 
C14H13N5O5S2
 
6915944 
Moderate    Inter Info   
[108]
D0320
 
Chloroquine
 
C18H26ClN3
 
2719 
Moderate    Inter Info   
[1], [2], [80], [112], [113], [114], [115], [116]
D0330
 
Cholic Acid
 
C24H40O5
 
221493 
Moderate    Inter Info   
[117]
D0340
 
Cinoxacin
 
C12H10N2O5
 
2762 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0341
 
Ciprofloxacin
 
C17H18FN3O3
 
2764 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0402
 
Cyclosporine
 
C62H111N11O12
 
5284373 
Moderate    Inter Info   
[118]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Moderate    Inter Info   
[120]
D0441
 
Demeclocycline
 
C21H21ClN2O8
 
54680690 
Moderate    Inter Info   
[23], [80], [81], [82], [83], [84], [85], [86], [87], [88], [62], [89], [72]
D0530
 
Doxycycline
 
C22H24N2O8
 
54671203 
Moderate    Inter Info   
[23], [80], [81], [82], [83], [84], [85], [86], [87], [88], [62], [89], [72]
D0561
 
Eltrombopag
 
C25H22N4O4
 
135449332 
Moderate    Inter Info   
[2], [122]
D0573
 
Enoxacin
 
C15H17FN4O3
 
3229 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0623
 
Etidronic acid
 
C2H8O7P2
 
3305 
Moderate    Inter Info   
[27], [128], [28]
D0656
 
Fexofenadine
 
C32H39NO4
 
3348 
Moderate    Inter Info   
[129]
D0712
 
Gatifloxacin
 
C19H22FN3O4
 
5379 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0716
 
Gemifloxacin
 
C18H20FN5O4
 
9571107 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0740
 
Grepafloxacin
 
C19H22FN3O3
 
72474 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0779
 
Hydroxychloroquine
 
C18H26ClN3O
 
3652 
Moderate    Inter Info   
[1], [2], [80], [112], [113], [114], [115], [116]
D0919
 
Levofloxacin
 
C18H20FN3O4
 
149096 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0934
 
Liothyronine
 
C15H12I3NO4
 
5920 
Moderate    Inter Info   
[138], [9], [1], [2], [139], [140], [93], [94], [95], [141], [142]
D0935
 
Liotrix
 
C30H21I7N2Na2O8
 
71371 
Moderate    Inter Info   
[138], [9], [1], [2], [139], [140], [93], [94], [95], [141], [142]
D0943
 
Lomefloxacin
 
C17H19F2N3O3
 
3948 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1070
 
Minocycline
 
C23H27N3O7
 
54675783 
Moderate    Inter Info   
[23], [80], [81], [82], [83], [84], [85], [86], [87], [88], [62], [89], [72]
D1092
 
Moxifloxacin
 
C21H24FN3O4
 
152946 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1102
 
Nalidixic acid
 
C12H12N2O3
 
4421 
Moderate    Inter Info   
[149]
D1155
 
Norfloxacin
 
C16H18FN3O3
 
4539 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1165
 
Ofloxacin
 
C18H20FN3O4
 
4583 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1209
 
Oxytetracycline
 
C22H24N2O9
 
54675779 
Moderate    Inter Info   
[23], [80], [81], [82], [83], [84], [85], [86], [87], [88], [62], [89], [72]
D1245
 
Penicillamine
 
C5H11NO2S
 
5852 
Moderate    Inter Info   
[156], [157], [158], [159], [160], [161], [162], [62]
D1412
 
Risedronic acid
 
C7H11NO7P2
 
5245 
Moderate    Inter Info   
[26], [27], [28]
D1499
 
Sparfloxacin
 
C19H22F2N4O3
 
60464 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1564
 
Tetracycline
 
C22H24N2O8
 
54675776 
Moderate    Inter Info   
[23], [80], [81], [82], [83], [84], [85], [86], [87], [88], [62], [89], [72]
D1584
 
Tiludronic acid
 
C7H9ClO6P2S
 
60937 
Moderate    Inter Info   
[27], [128], [28]
D1657
 
Trovafloxacin
 
C20H15F3N4O3
 
62959 
Moderate    Inter Info   
[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0010
 
Acebutolol
 
C18H28N2O4
 
1978 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D0117
 
Atenolol
 
C14H22N2O3
 
2249 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D0173
 
Betaxolol
 
C18H29NO3
 
2369 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D0188
 
Bisoprolol
 
C18H31NO4
 
2405 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D0267
 
Carvedilol
 
C24H26N2O4
 
2585 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D0490
 
Digitoxin
 
C41H64O13
 
441207 
Minor    Inter Info   
[207], [208], [209], [80], [210], [211], [62], [212], [213]
D0491
 
Digoxin
 
C41H64O14
 
2724385 
Minor    Inter Info   
[207], [208], [209], [80], [210], [211], [62], [212], [213]
D0705
 
Gabapentin
 
C9H17NO2
 
3446 
Minor    Inter Info   
[215]
D0884
 
Labetalol
 
C19H24N2O3
 
3869 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1049
 
Metoprolol
 
C15H25NO3
 
4171 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1098
 
Nadolol
 
C17H27NO4
 
39147 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1114
 
Nebivolol
 
C22H25F2NO4
 
71301 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1293
 
Pindolol
 
C14H20N2O2
 
4828 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1357
 
Propranolol
 
C16H21NO2
 
4946 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1585
 
Timolol
 
C13H24N4O3S
 
33624 
Minor    Inter Info   
[80], [169], [170], [171], [172], [173], [174]
D1670
 
Ursodeoxycholic acid
 
C24H40O4
 
31401 
Minor    Inter Info   
[225]
   Adsorption Drug Num:  11
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0123
 
Atropine
 
C17H23NO3
 
174174 
Moderate    Inter Info   
[2]
D1350
 
Proguanil
 
C11H16ClN5
 
6178111 
Moderate    Inter Info   
[2], [150]
D1354
 
Propantheline
 
C23H30NO3+
 
4934 
Moderate    Inter Info   
[1]
D1366
 
Pyrimethamine
 
C12H13ClN4
 
4993 
Moderate    Inter Info   
[2], [150]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Minor    Inter Info   
[23], [191], [192], [193], [194]
D1010
 
Mesoridazine
 
C21H26N2OS2
 
4078 
Minor    Inter Info   
[23], [191], [192], [193], [194]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Minor    Inter Info   
[23], [191], [192], [193], [194]
D1346
 
Prochlorperazine
 
C20H24ClN3S
 
4917 
Minor    Inter Info   
[23], [191], [192], [193], [194]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Minor    Inter Info   
[23], [191], [192], [193], [194]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Minor    Inter Info   
[23], [191], [192], [193], [194]
D1637
 
Trifluoperazine
 
C21H24F3N3S
 
5566 
Minor    Inter Info   
[23], [191], [192], [193], [194]
   Altered gastric pH Drug Num:  68
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1459
 
Selpercatinib
 
C29H31N7O3
 
134436906 
Major    Inter Info   
[14]
D0013
 
Acetohexamide
 
C15H20N2O4S
 
1989 
Moderate    Inter Info   
[16], [17], [18], [19], [20], [21], [22]
D0008
 
Acalabrutinib
 
C26H23N7O2
 
71226662 
Moderate    Inter Info   
[30]
D0184
 
Bisacodyl
 
C22H19NO4
 
2391 
Moderate    Inter Info   
[2]
D0229
 
Cabotegravir
 
C19H17F2N3O5
 
54713659 
Moderate    Inter Info   
[1], [32], [33], [34]
D0406
 
Dabrafenib
 
C23H20F3N5O2S2
 
44462760 
Moderate    Inter Info   
[1], [2], [35], [36], [37], [38], [39]
D0898
 
Ledipasvir
 
C49H54F2N8O6
 
67505836 
Moderate    Inter Info   
[73]
D1124
 
Neratinib
 
C30H29ClN6O3
 
9915743 
Moderate    Inter Info   
[79]
D1258
 
Pexidartinib
 
C20H15ClF3N5
 
25151352 
Moderate    Inter Info   
[90]
D1404
 
Rilpivirine
 
C22H18N6
 
6451164 
Moderate    Inter Info   
[91]
D1408
 
Riociguat
 
C20H19FN8O2
 
11304743 
Moderate    Inter Info   
[92]
D1686
 
Velpatasvir
 
C49H54N8O8
 
67683363 
Moderate    Inter Info   
[96]
D0074
 
Amphetamine
 
C9H13N
 
3007 
Moderate    Inter Info   
[97]
D0080
 
Amprenavir
 
C25H35N3O6S
 
65016 
Moderate    Inter Info   
[98], [99]
D0116
 
Atazanavir
 
C38H52N6O7
 
148192 
Moderate    Inter Info   
[101], [102], [103]
D0141
 
Bacampicillin
 
C21H27N3O7S
 
441397 
Moderate    Inter Info   
[47], [105]
D0165
 
Benzphetamine
 
C17H21N
 
5311017 
Moderate    Inter Info   
[97]
D0195
 
Bosutinib
 
C26H29Cl2N5O3
 
5328940 
Moderate    Inter Info   
[2], [106]
D0278
 
Cefditoren
 
C19H18N6O5S3
 
9870843 
Moderate    Inter Info   
[109]
D0288
 
Cefpodoxime
 
C15H17N5O6S2
 
6335986 
Moderate    Inter Info   
[47], [110], [111], [105]
D0297
 
Cefuroxime
 
C16H16N4O8S
 
5479529 
Moderate    Inter Info   
[47], [110], [111], [105]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Moderate    Inter Info   
[16], [17], [18], [19], [20], [21], [22]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Moderate    Inter Info   
[119]
D0465
 
Dextroamphetamine
 
C9H13N
 
5826 
Moderate    Inter Info   
[97]
D0595
 
Erlotinib
 
C22H23N3O4
 
176870 
Moderate    Inter Info   
[1], [2], [123], [124]
D0727
 
Glimepiride
 
C24H34N4O5S
 
3476 
Moderate    Inter Info   
[16], [17], [18], [19], [20], [21], [22]
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Moderate    Inter Info   
[16], [17], [18], [19], [20], [21], [22]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Moderate    Inter Info   
[16], [17], [18], [19], [20], [21], [22]
D0867
 
Itraconazole
 
C35H38Cl2N8O4
 
55283 
Moderate    Inter Info   
[130], [131], [132], [133], [134]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Moderate    Inter Info   
[130], [131], [135], [32], [2], [136], [137], [134]
D0937
 
Lisdexamfetamine
 
C15H25N3O
 
11597698 
Moderate    Inter Info   
[97]
D1012
 
Metamfetamine
 
C10H15N
 
10836 
Moderate    Inter Info   
[143], [97], [144]
D1094
 
Mycophenolate mofetil
 
C23H31NO7
 
5281078 
Moderate    Inter Info   
[145], [146], [147], [148]
D1095
 
Mycophenolic acid
 
C17H20O6
 
446541 
Moderate    Inter Info   
[145], [146], [147], [148]
D1218
 
Pancrelipase
 
C8H8Na2O5
 
8519 
Moderate    Inter Info   
[1], [2], [150]
D1232
 
Pazopanib
 
C21H23N7O2S
 
10113978 
Moderate    Inter Info   
[2], [151], [152], [153], [154], [155]
D1400
 
Rifampicin
 
C43H58N4O12
 
135398735 
Moderate    Inter Info   
[166]
D1430
 
Rosuvastatin
 
C22H28FN3O6S
 
446157 
Moderate    Inter Info   
[167]
D1592
 
Tipranavir
 
C31H33F3N2O5S
 
54682461 
Moderate    Inter Info   
[168], [103]
D1313
 
Ponatinib
 
C29H27F3N6O
 
24826799 
Minor    Inter Info   
[1], [184]
D1701
 
Vismodegib
 
C19H14Cl2N2O3S
 
24776445 
Minor    Inter Info   
[1], [2], [185]
D0133
 
Axitinib
 
C22H18N4OS
 
6450551 
Minor    Inter Info   
[186]
D0156
 
Benazepril
 
C24H28N2O5
 
5362124 
Minor    Inter Info   
[187]
D0172
 
Betamethasone
 
C22H29FO5
 
9782 
Minor    Inter Info   
[188], [189], [190]
D0254
 
Captopril
 
C9H15NO3S
 
44093 
Minor    Inter Info   
[187]
D0337
 
Cimetidine
 
C10H16N6S
 
2756 
Minor    Inter Info   
[195], [188], [196], [197], [198], [23], [199], [200], [201], [202], [203], [204]
D0453
 
Dexamethasone
 
C22H29FO5
 
5743 
Minor    Inter Info   
[188], [189], [190]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Minor    Inter Info   
[214]
D0567
 
Enalapril
 
C20H28N2O5
 
5388962 
Minor    Inter Info   
[187]
D0636
 
Famotidine
 
C8H15N7O2S3
 
5702160 
Minor    Inter Info   
[195], [188], [196], [197], [198], [23], [199], [200], [201], [202], [203], [204]
D0671
 
Fludrocortisone
 
C21H29FO5
 
31378 
Minor    Inter Info   
[188], [189], [190]
D0695
 
Fosinopril
 
C30H46NO7P
 
55891 
Minor    Inter Info   
[187]
D0773
 
Hydrocortisone
 
C21H30O5
 
5754 
Minor    Inter Info   
[188], [189], [190]
D0918
 
Levodopa
 
C9H11NO4
 
6047 
Minor    Inter Info   
[218], [219], [220], [221]
D0938
 
Lisinopril
 
C21H31N3O5
 
5362119 
Minor    Inter Info   
[187]
D1041
 
Methylprednisolone
 
C22H30O5
 
6741 
Minor    Inter Info   
[188], [189], [190]
D1082
 
Moexipril
 
C27H34N2O7
 
91270 
Minor    Inter Info   
[187]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Minor    Inter Info   
[222], [223]
D1151
 
Nizatidine
 
C12H21N5O2S2
 
3033637 
Minor    Inter Info   
[195], [188], [196], [197], [198], [23], [199], [200], [201], [202], [203], [204]
D1256
 
Perindopril
 
C19H32N2O5
 
107807 
Minor    Inter Info   
[187]
D1332
 
Prednisolone
 
C21H28O5
 
5755 
Minor    Inter Info   
[188], [189], [190]
D1334
 
Prednisone
 
C21H26O5
 
5865 
Minor    Inter Info   
[188], [189], [190]
D1369
 
Quinapril
 
C25H30N2O5
 
54892 
Minor    Inter Info   
[187]
D1379
 
Ramipril
 
C23H32N2O5
 
5362129 
Minor    Inter Info   
[187]
D1381
 
Ranitidine
 
C13H22N4O3S
 
3001055 
Minor    Inter Info   
[195], [188], [196], [197], [198], [23], [199], [200], [201], [202], [203], [204]
D1581
 
Ticlopidine
 
C14H14ClNS
 
5472 
Minor    Inter Info   
[224]
D1618
 
Trandolapril
 
C24H34N2O5
 
5484727 
Minor    Inter Info   
[187]
D1628
 
Triamcinolone
 
C21H27FO6
 
31307 
Minor    Inter Info   
[188], [189], [190]
   Altered absorption (Unspecific) Drug Num:  8
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0527
 
Doxercalciferol
 
C28H44O2
 
5281107 
Major    Inter Info   
[2], [15]
D1226
 
Paricalcitol
 
C27H44O3
 
5281104 
Major    Inter Info   
[2], [15]
D0040
 
Allopurinol
 
C5H4N4O
 
135401907 
Moderate    Inter Info   
[1], [2], [29]
D0111
 
Ascorbic acid
 
C6H8O6
 
54670067 
Moderate    Inter Info   
[2], [100]
D0439
 
Delavirdine
 
C22H28N6O3S
 
5625 
Moderate    Inter Info   
[121]
D0616
 
Ethambutol
 
C10H24N2O2
 
14052 
Moderate    Inter Info   
[125], [126], [127]
D0489
 
Diflunisal
 
C13H8F2O3
 
3059 
Minor    Inter Info   
[80], [205], [206]
D0858
 
Isoniazid
 
C6H7N3O
 
3767 
Minor    Inter Info   
[216], [217]
      Affected excretion pathways
   Altered urine pH Drug Num:  6
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Moderate    Inter Info   
[23], [24], [25]
D0331
 
Choline salicylate
 
C12H19NO4
 
54686350 
Moderate    Inter Info   
[23], [24], [25]
D1020
 
Methenamine
 
C6H12N4
 
4101 
Moderate    Inter Info   
[74], [75], [76], [77], [78]
D1371
 
Quinidine
 
C20H24N2O2
 
441074 
Moderate    Inter Info   
[163], [164], [165]
D1439
 
Salicylic acid (sodium)
 
C7H6O3
 
338 
Moderate    Inter Info   
[23], [24], [25]
D1442
 
Salsalate
 
C14H10O5
 
5161 
Moderate    Inter Info   
[23], [24], [25]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0590
 
Erdafitinib
 
C25H30N6O2
 
67462786 
Major    Inter Info   
[5]
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128 Product Information. Fosamax (alendronate). Merck &amp Co, Inc, West Point, PA.
129 Product Information. Allegra (fexofenadine). Hoechst Marion-Roussel Inc, Kansas City, MO.
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150 Multum Information Services, Inc. Expert Review Panel.
151 EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
152 Product Information. Votrient (pazopanib). GlaxoSmithKline, Research Triangle Park, NC.
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166 Product Information. Rifadin (rifampin). Hoechst Marion-Roussel Inc, Kansas City, MO.
167 Product Information. Crestor (rosuvastatin). AstraZeneca Pharma Inc, Mississauga, ON.
168 Product Information. Aptivus (tipranavir). Boehringer-Ingelheim, Ridgefield, CT.
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184 Product Information. Iclusig (ponatinib). Ariad Pharmaceuticals Inc, Cambridge, MA.
185 Product Information. Erivedge (vismodegib). Genentech, South San Francisco, CA.
186 Product Information. Inlyta (axitinib). Pfizer U.S. Pharmaceuticals Group, New York, NY.
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205 Product Information. Dolobid (diflunisal). Merck & Co, Inc, West Point, PA.
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214 Product Information. Cymbalta (duloxetine). Lilly, Eli and Company, Indianapolis, IN.
215 Product Information. Neurontin (gabapentin). Parke-Davis, Morris Plains, NJ.
216 Hava M, Hurwitz A "The relaxing effect of aluminum and lanthanum on rat and human gastric smooth muscle in vitro." Eur J Pharmacol 156 (1973): 156-61. [PMID: 4715218]
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218 Fermaglich J, O'Dougherty DS "Effect of gastric motility on levodopa." Dis Nerv Syst 33 (1972): 624-5. [PMID: 4649158]
219 Product Information. Sinemet (carbidopa-levodopa). DuPont Pharmaceuticals, Wilmington, DE.
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222 Brogden RN, Heel RC, Speight TM, Avery GS "Naproxen up to date: a review of its pharmacological properties and therapeutic efficacy and use in rheumatic diseases and pain states." Drugs 18 (1979): 241-77. [PMID: 387372]
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224 Product Information. Ticlid (ticlopidine). Syntex Laboratories Inc, Palo Alto, CA.
225 Product Information. Actigall capsules (ursodiol). Novartis Pharmaceutical, Research Triangle Pk, NC.