Drug General Information (ID: DDI5N9QK3D)
  Drug Name Ursodeoxycholic acid Drug Info Aluminum hydroxide Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Choleretic Agents Antacids
  Structure

 Mechanism of Ursodeoxycholic acid-Aluminum hydroxide Interaction (Severity Level: Minor)
     Complex formation Click to Show/Hide Mechanism Graph
Could Not Find 2D Structure
      Drug Name Ursodeoxycholic acid Aluminum hydroxide
      Mechanism Binds to polyvalent cations Polyvalent cations
      Key Mechanism Factor 1
Factor Name Chelation
Factor Description Chelation is a direct drug interaction that usually involves the formation of dimers or trimers, resulting in larger complexes and poorer absorption.
      Mechanism Description
  • Decreased absorption of Aluminum hydroxide due to formation of complexes caused by Ursodeoxycholic acid 

References
1 Product Information. Actigall capsules (ursodiol). Novartis Pharmaceutical, Research Triangle Pk, NC.