Drug General Information (ID: DDIFK3SV6O)
Drug Name			Doxercalciferol		Drug Info		Aluminum hydroxide		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Vitamins				Antacids
Structure

Mechanism of Doxercalciferol-Aluminum hydroxide Interaction (Severity Level: Major)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Doxercalciferol				Aluminum hydroxide
Mechanism		Increase absorption of aluminum				Aluminum-containing products
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Aluminum hydroxide caused by Doxercalciferol

Recommended Action
Management		Aluminum-containing preparations (e.g., antacids, phosphate binders) should not be administered chronically with vitamin D analogs.

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Product Information. Zemplar (paricalcitol). Abbott Pharmaceutical, Abbott Park, IL.