Drug General Information (ID: DDI4LXFKU6)
Drug Name			Cefdinir		Drug Info		Aluminum hydroxide		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antibiotics				Antacids
Structure

Mechanism of Cefdinir-Aluminum hydroxide Interaction (Severity Level: Moderate)
Complex formation Click to Show/Hide Mechanism Graph
Drug Name		Cefdinir				Aluminum hydroxide
Mechanism		Binds to polyvalent cations				Polyvalent cations
Key Mechanism Factor 1
		Factor Name		Chelation
		Factor Description		Chelation is a direct drug interaction that usually involves the formation of dimers or trimers, resulting in larger complexes and poorer absorption.
Mechanism Description		Decreased absorption of Aluminum hydroxide due to formation of complexes caused by Cefdinir

Recommended Action
Management		If an antacid must be administered during cefdinir therapy, separate the times of administration by at least two hours.

References
1	Product Information. Omnicef (cefdinir). Parke-Davis, Morris Plains, NJ.