Details of Drug

Drug General Information (ID: D1437)
Drug Name	Safinamide
Drug Type	Small molecule
Drug Synonymous	133865-89-1; Xadago; (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide; Fce-26743; UNII-90ENL74SIG; (2S)-2-[[4-[(3-Fluorophenyl)methoxy]phenyl]methylamino]propanamide; EMD 1195686; 90ENL74SIG; CHEMBL396778; EMD-1195686; AK-77847; 2(s)-(4-(3-fluorobenzyloxy)benzylamino)propionamide; CHEMBL48582; Safinamide [USAN:INN]; 2-(4-(3-Fluorobenzyloxy)benzylamino)propionamide; AC1L2ZLK; Safinamide (USAN/INN); (S)-2-(((4-((3-Fluorophenyl)methoxy)phenyl)methyl)amino)propanamide; EC 603-772-2; SCHEMBL69350; Fce 26743; ON 019190.Na Click to Show/Hide
Disease Class	8A00: Parkinsonism
Therapeutic Class	Dopaminergic Antiparkinsonism Agents
Structure
Structure	3D Structure		2D Structure
Formula	C17H19FN2O2
InChI	1S/C17H19FN2O2/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14/h2-9,12,20H,10-11H2,1H3,(H2,19,21)/t12-/m0/s1
InChIKey	NEMGRZFTLSKBAP-LBPRGKRZSA-N
Canonical SMILES	CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F
External Link
	Pubchem ID	131682
	CAS Number	133865-89-1
	CHEBI ID	134718
	TTD ID	D0TV6I
	VARIDT ID	DR00042

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM002 Affected cellular transport AM003 Affected organization distribution AM004 Affected intra/extra-hepatic metabolism AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM010 Transporter inhibition BM014 Interference of cell/tissue uptake BM018 Non-CYP450 enzyme inhibition BM038 Additive CNS depression effects BM040 Additive dopaminergic effects BM041 Additive hypertensive effects BM042 Additive hypotensive effects BM046 Additive serotonergic effects BM051 Increased risk of bradycardia BM061 Increased risk of hyperpyrexia BM064 Increased risk of hypoglycemia BM069 Increased risk of lowers seizure threshold BM078 Increased risk of rapid heart rate BM089 Antagonize the effect of antihypertensive agents
Relation Graph

Full list of drugs interacting with Safinamide
Affected cellular transport
	Transporter inhibition					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0171		Berotralstat	C30H26F4N6O	137528262	Major		Inter Info	[138]
D0182		Binimetinib	C17H15BrF2N4O3	10288191	Moderate		Inter Info	[12], [13], [299]
D1407		Rimegepant	C28H28F2N6O3	51049968	Moderate		Inter Info	[301]
D1532		Talazoparib	C19H14F2N6O	135565082	Moderate		Inter Info	[302]
D1663		Ubrogepant	C29H26F3N5O3	68748835	Moderate		Inter Info	[303]
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0829		Iobenguane (I-131)	C8H10IN3	60860	Major		Inter Info	[143]
Affected intra/extra-hepatic metabolism
	Non-CYP450 enzyme inhibition					Drug Num: 30
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1035		Methyldopa	C10H13NO4	38853	Major		Inter Info	[17], [20], [134], [53], [135], [75], [136], [137]
D1211		Ozanimod	C23H24N4O3	52938427	Major		Inter Info	[144]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D0486		Diethylpropion	C13H19NO	7029	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D0505		Dipivefrin (ophthalmic)	C19H29NO5	3105	Moderate		Inter Info	[273], [17], [73]
D0517		Dopamine	C8H11NO2	681	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D0523		Doxapram	C24H30N2O2	3156	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D0579		Ephedrine	C10H15NO	9294	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D0580		Ephedrine (nasal)	C10H15NO	9294	Moderate		Inter Info	[273], [17], [73]
D0582		Epinephrine (ophthalmic)	C9H13NO3	5816	Moderate		Inter Info	[273], [17], [73]
D0583		Epinephrine (topical)	C9H13NO3	5816	Moderate		Inter Info	[273], [17], [73]
D0981		Mazindol	C16H13ClN2O	4020	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D1002		Mephentermine	C11H17N	3677	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[273], [17], [73]
D1013		Metaraminol	C9H13NO2	5906	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D1204		Oxymetazoline (nasal)	C16H24N2O	4636	Moderate		Inter Info	[273], [17], [73]
D1205		Oxymetazoline (ophthalmic)	C16H24N2O	4636	Moderate		Inter Info	[273], [17], [73]
D1206		Oxymetazoline (topical)	C16H24N2O	4636	Moderate		Inter Info	[273], [17], [73]
D1270		Phentermine	C10H15N	4771	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D1276		Phenylephrine	C9H13NO2	6041	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D1277		Phenylephrine (nasal)	C9H13NO2	6041	Moderate		Inter Info	[273], [17], [73]
D1278		Phenylephrine (ophthalmic)	C9H13NO2	6041	Moderate		Inter Info	[273], [17], [73]
D1280		Phenylephrine (topical)	C9H13NO2	6041	Moderate		Inter Info	[273], [17], [73]
D1363		Pseudoephedrine	C10H15NO	7028	Moderate		Inter Info	[272], [91], [93], [12], [13], [273], [17], [20], [97], [274], [28], [98], [53], [73], [75], [275], [108], [276], [88]
D0857		Isometheptene	C9H19N	22297	Moderate		Inter Info	[273], [17], [73]
D0913		Levmetamfetamine (nasal)	C10H15N	36604	Moderate		Inter Info	[273], [17], [276]
D1107		Naphazoline (nasal)	C14H14N2	4436	Moderate		Inter Info	[273], [17], [276]
D1358		Propylhexedrine (nasal)	C10H21N	7558	Moderate		Inter Info	[273], [17], [276]
D1567		Tetryzoline (nasal)	C13H16N2	5419	Moderate		Inter Info	[273], [17], [276]
D1568		Tetryzoline (ophthalmic)	C13H16N2	5419	Moderate		Inter Info	[273], [17], [73]
Pharmacodynamic additive effects
	Additive CNS depression effects					Drug Num: 20
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0035		Alfentanil	C21H32N6O3	51263	Major		Inter Info	[1], [2], [3]
D1090		Morphine (liposomal)	C17H19NO3	5288826	Major		Inter Info	[1], [2], [3]
D1390		Remifentanil	C20H28N2O5	60815	Major		Inter Info	[1], [2], [3]
D1169		Oliceridine	C22H30N2O2S	66553195	Major		Inter Info	[1], [2], [3]
D1512		Sufentanil	C22H30N2O2S	41693	Major		Inter Info	[1], [2], [3]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[28], [53], [255]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D0617		Ethanol	C2H6O	702	Moderate		Inter Info	[282], [283], [284], [13], [285]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1010		Mesoridazine	C21H26N2OS2	4078	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1019		Methdilazine	C18H20N2S	14677	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1257		Perphenazine	C21H26ClN3OS	4748	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1355		Propiomazine	C20H24N2OS	4940	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D0201		Brexanolone	C21H34O2	92786	Moderate		Inter Info	[300]
D1572		Thiethylperazine	C22H29N3S2	5440	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1574		Thioridazine	C21H26N2S2	5452	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
D1638		Triflupromazine	C18H19F3N2S	5568	Moderate		Inter Info	[91], [278], [20], [28], [252], [279], [151], [53], [280], [65], [66], [68], [69], [281], [255]
	Additive dopaminergic effects					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1492		Solriamfetol	C10H14N2O2	10130337	Major		Inter Info	[145]
	Additive hypertensive effects					Drug Num: 29
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0074		Amphetamine	C9H13N	3007	Major		Inter Info	[91], [92], [93], [13], [94], [95], [17], [96], [97], [28], [98], [99], [100], [101], [102], [43], [103], [104], [56], [105], [73], [106], [107], [108], [109], [88]
D0098		Apraclonidine	C9H10Cl2N4	2216	Major		Inter Info	[20], [110], [75]
D0220		Bupropion	C13H18ClNO	444	Major		Inter Info	[20], [111], [53], [112], [113], [75]
D0465		Dextroamphetamine	C9H13N	5826	Major		Inter Info	[91], [92], [93], [13], [94], [95], [17], [96], [97], [28], [98], [99], [100], [101], [102], [43], [103], [104], [56], [105], [73], [106], [107], [108], [109], [88]
D0933		Linezolid	C16H20FN3O4	441401	Major		Inter Info	[132], [73], [113], [133]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Major		Inter Info	[91], [92], [93], [13], [94], [95], [17], [96], [97], [28], [98], [99], [100], [101], [102], [43], [103], [104], [56], [105], [73], [106], [107], [108], [109], [88]
D1039		Methylphenidate	C14H19NO2	4158	Major		Inter Info	[91], [92], [93], [13], [94], [95], [17], [96], [97], [28], [98], [99], [100], [101], [102], [43], [103], [104], [56], [105], [73], [106], [107], [108], [109], [88]
D0452		Deutetrabenazine	C19H27NO3	73437646	Major		Inter Info	[139], [140], [141]
D0460		Dexmethylphenidate	C14H19NO2	154101	Major		Inter Info	[91], [92], [93], [13], [94], [95], [17], [96], [97], [28], [98], [99], [100], [101], [102], [43], [103], [104], [56], [105], [73], [106], [107], [108], [109], [88]
D0600		Esketamine	C13H16ClNO	182137	Major		Inter Info	[12], [142]
D1560		Tetrabenazine	C19H27NO3	6018	Major		Inter Info	[139], [140], [141]
D0103		Arformoterol	C19H24N2O4	3083544	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D0205		Brimonidine (ophthalmic)	C11H10BrN5	2435	Moderate		Inter Info	[277], [151], [75]
D0206		Brimonidine (topical)	C11H10BrN5	2435	Moderate		Inter Info	[277], [151], [75]
D0691		Formoterol	C19H24N2O4	3410	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D0797		Indacaterol	C24H28N2O3	6918554	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D0854		Isoetharine	C13H21NO3	3762	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D0859		Isoprenaline	C11H17NO3	3779	Moderate		Inter Info	[92], [262], [271]
D0879		Ketamine	C13H16ClNO	3821	Moderate		Inter Info	[12], [13], [296]
D1185		Orciprenaline	C11H17NO3	4086	Moderate		Inter Info	[92], [262], [271]
D1298		Pirbuterol	C12H20N2O3	4845	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D1414		Ritodrine	C17H21NO3	33572	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D0924		Levosalbutamol	C13H21NO3	123600	Moderate		Inter Info	[92], [262], [271]
D1171		Olodaterol	C21H26N2O5	11504295	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D1374		Racepinephrine	C9H13NO3	838	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D1695		Vilanterol	C24H33Cl2NO5	10184665	Moderate		Inter Info	[92], [262], [271]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[92], [262], [271]
D1440		Salmeterol	C25H37NO4	5152	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[256], [92], [17], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271]
	Additive hypotensive effects					Drug Num: 103
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0010		Acebutolol	C18H28N2O4	1978	Moderate		Inter Info	[151], [65], [66]
D0030		Aldesleukin	NA	NA	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0058		Amiloride	C6H8ClN7O	16231	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0069		Amlodipine	C20H25ClN2O5	2162	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0082		Amrinone	C10H9N3O	3698	Moderate		Inter Info	[65], [254], [75]
D0083		Amyl Nitrite	C5H11NO2	10026	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0117		Atenolol	C14H22N2O3	2249	Moderate		Inter Info	[151], [65], [66]
D0128		Avanafil	C23H26ClN7O3	9869929	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0156		Benazepril	C24H28N2O5	5362124	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0158		Bendroflumethiazide	C15H14F3N3O4S2	2315	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0170		Bepridil	C24H34N2O	2351	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0173		Betaxolol	C18H29NO3	2369	Moderate		Inter Info	[151], [65], [66]
D0174		Betaxolol (ophthalmic)	C18H29NO3	2369	Moderate		Inter Info	[151], [65], [66]
D0188		Bisoprolol	C18H31NO4	2405	Moderate		Inter Info	[151], [65], [66]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0254		Captopril	C9H15NO3S	44093	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0265		Carteolol	C16H24N2O3	2583	Moderate		Inter Info	[151], [65], [66]
D0266		Carteolol (ophthalmic)	C16H24N2O3	2583	Moderate		Inter Info	[151], [65], [66]
D0267		Carvedilol	C24H26N2O4	2585	Moderate		Inter Info	[151], [65], [66]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0352		Clevidipine	C21H23Cl2NO6	153994	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0363		Clonidine	C9H9Cl2N3	2803	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0396		Cyclandelate	C17H24O3	2893	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0474		Diazoxide	C8H7ClN2O2S	3019	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0524		Doxazosin	C23H25N5O5	3157	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0567		Enalapril	C20H28N2O5	5388962	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0585		Eplerenone	C24H30O6	443872	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0586		Epoprostenol	C20H32O5	5282411	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0587		Eprosartan	C23H24N2O4S	5281037	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0602		Esmolol	C16H25NO4	59768	Moderate		Inter Info	[151], [65], [66]
D0613		Etacrynic acid	C13H12Cl2O4	3278	Moderate		Inter Info	[65], [254], [75]
D0640		Felodipine	C18H19Cl2NO4	3333	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0644		Fenoldopam	C16H16ClNO3	3341	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0695		Fosinopril	C30H46NO7P	55891	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0745		Guanfacine	C9H9Cl2N3O	3519	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0792		Iloprost	C22H32O4	5311181	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0844		Irbesartan	C25H28N6O	3749	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0861		Isosorbide dinitrate	C6H8N2O8	6883	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0862		Isosorbide mononitrate	C6H9NO6	27661	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0865		Isradipine	C19H21N3O5	3784	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0884		Labetalol	C19H24N2O3	3869	Moderate		Inter Info	[151], [65], [66]
D0915		Levobunolol (ophthalmic)	C17H25NO3	39468	Moderate		Inter Info	[151], [65], [66]
D0938		Lisinopril	C21H31N3O5	5362119	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0942		Lofexidine	C11H12Cl2N2O	30668	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0954		Losartan	C22H23ClN6O	3961	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0980		Maraviroc	C29H41F2N5O	3002977	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0983		Mecamylamine	C11H21N	4032	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1045		Metipranolol (ophthalmic)	C17H27NO4	31477	Moderate		Inter Info	[151], [65], [66]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1049		Metoprolol	C15H25NO3	4171	Moderate		Inter Info	[151], [65], [66]
D1067		Milrinone	C12H9N3O	4197	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1072		Minoxidil	C9H15N5O	4201	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1082		Moexipril	C27H34N2O7	91270	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1098		Nadolol	C17H27NO4	39147	Moderate		Inter Info	[151], [65], [66]
D1114		Nebivolol	C22H25F2NO4	71301	Moderate		Inter Info	[151], [65], [66]
D1125		Nesiritide	C143H244N50O42S4	53325981	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1130		Nicardipine	C26H29N3O6	4474	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1141		Nisoldipine	C20H24N2O6	4499	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1146		Nitroglycerin	C3H5N3O9	4510	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1147		Nitroprusside	C5FeN6O	11953891	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1170		Olmesartan	C24H26N6O3	158781	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1223		Papaverine	C20H21NO4	4680	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1244		Penbutolol	C18H29NO2	37464	Moderate		Inter Info	[151], [65], [66]
D1271		Phentolamine	C17H19N3O	5775	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1293		Pindolol	C14H20N2O2	4828	Moderate		Inter Info	[151], [65], [66]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1331		Prazosin	C19H21N5O4	4893	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1357		Propranolol	C16H21NO2	4946	Moderate		Inter Info	[151], [65], [66]
D1369		Quinapril	C25H30N2O5	54892	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1379		Ramipril	C23H32N2O5	5362129	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0038		Aliskiren	C30H53N3O6	5493444	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0138		Azilsartan medoxomil	C30H24N4O8	135409642	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0860		Isosorbide	C6H10O4	12597	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0864		Isoxsuprine	C18H23NO3	3783	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0911		Levamlodipine	C20H25ClN2O5	9822750	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D0914		Levobetaxolol (ophthalmic)	C18H29NO3	60657	Moderate		Inter Info	[151], [65], [66]
D1457		Selexipag	C26H32N4O4S	9913767	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1465		Sildenafil	C22H30N6O4S	135398744	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1466		Silodosin	C25H32F3N3O4	5312125	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1498		Sotalol	C12H20N2O3S	5253	Moderate		Inter Info	[151], [65], [66]
D1501		Spironolactone	C24H32O4S	5833	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1527		Tadalafil	C22H19N3O4	110635	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1534		Tamsulosin	C20H28N2O5S	129211	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1545		Telmisartan	C33H30N4O2	65999	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1585		Timolol	C13H24N4O3S	33624	Moderate		Inter Info	[151], [65], [66]
D1586		Timolol (ophthalmic)	C13H24N4O3S	33624	Moderate		Inter Info	[151], [65], [66]
D1602		Tolazoline	C10H12N2	5504	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[65], [254], [75]
D1618		Trandolapril	C24H34N2O5	5484727	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1625		Treprostinil	C23H34O5	6918140	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1631		Triamterene	C12H11N7	5546	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1643		Trimethaphan	C22H25N2OS+	23576	Moderate		Inter Info	[65], [254], [75]
D1679		Valsartan	C24H29N5O3	60846	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
D1690		Verapamil	C27H38N2O4	2520	Moderate		Inter Info	[91], [20], [28], [252], [151], [53], [65], [66], [68], [69], [253], [254], [75]
	Additive serotonergic effects					Drug Num: 51
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0068		Amitriptyline	C20H23N	2160	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0072		Amoxapine	C17H16ClN3O	2170	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0222		Buspirone	C21H31N5O2	2477	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0361		Clomipramine	C19H23ClN2	2801	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0398		Cyclobenzaprine	C20H21N	2895	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0446		Desipramine	C18H22N2	2995	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0457		Dexfenfluramine	C12H16F3N	66265	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0466		Dextromethorphan	C18H25NO	5360696	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [12], [13], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0467		Dextropropoxyphene	C22H29NO2	10100	Major		Inter Info	[60], [63], [80]
D0494		Dihydroergotamine	C33H37N5O5	10531	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0525		Doxepin	C19H21NO	667477	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0526		Doxepin (topical)	C19H21NO	667477	Major		Inter Info	[77], [80], [82]
D0539		Duloxetine	C18H19NOS	60835	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0593		Ergotamine	C33H35N5O5	8223	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0641		Fenfluramine	C12H16F3N	3337	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0646		Fentanyl	C22H28N2O	3345	Major		Inter Info	[114], [12], [13], [15], [115], [20], [116], [117], [27], [118], [28], [32], [119], [46], [120], [49], [50], [121], [53], [122], [56], [123], [124], [60], [63], [65], [66], [125], [67], [68], [69], [75], [126], [80], [127], [128], [129], [130], [131], [3]
D0795		Imipramine	C19H24N2	3696	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0853		Isocarboxazid	C12H13N3O2	3759	Major		Inter Info	[56], [60], [1]
D0979		Maprotiline	C20H23N	4011	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1001		Meperidine	C15H21NO2	4058	Major		Inter Info	[114], [12], [13], [15], [115], [20], [116], [117], [27], [118], [28], [32], [119], [46], [120], [49], [50], [121], [53], [122], [56], [123], [124], [60], [63], [65], [66], [125], [67], [68], [69], [73], [75], [126], [80], [127], [128], [129], [130], [131], [3]
D1017		Methadone	C21H27NO	4095	Major		Inter Info	[114], [12], [13], [15], [115], [20], [116], [117], [27], [118], [28], [32], [119], [46], [120], [49], [50], [121], [53], [122], [56], [123], [124], [60], [63], [65], [66], [125], [67], [68], [69], [73], [75], [126], [80], [127], [128], [129], [130], [131], [3]
D1066		Milnacipran	C15H22N2O	65833	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1075		Mirtazapine	C17H19N3	4205	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1117		Nefazodone	C25H32ClN5O2	4449	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D1158		Nortriptyline	C19H21N	4543	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1200		Oxitriptan	C11H12N2O3	439280	Major		Inter Info	[29], [41], [44]
D1263		Phenelzine	C8H12N2	3675	Major		Inter Info	[56], [60], [1]
D1345		Procarbazine	C12H19N3O	4915	Major		Inter Info	[56], [60], [1]
D1361		Protriptyline	C19H21N	4976	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0451		Desvenlafaxine	C16H25NO2	125017	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0897		Lasmiditan	C19H18F3N3O2	11610526	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0920		Levomilnacipran	C15H22N2O	6917779	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1036		Methylene blue	C16H18ClN3S	6099	Major		Inter Info	[56], [60], [1]
D1252		Pentoxyverine	C20H31NO3	2562	Major		Inter Info	[8], [14], [34]
D1673		Valbenazine	C24H38N2O4	24795069	Major		Inter Info	[146], [66], [113]
D1696		Vilazodone	C26H27N5O2	6918314	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D1708		Vortioxetine	C18H22N2S	9966051	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1464		Sibutramine	C17H26ClN	5210	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D1502		St. John's Wort	NA	NA	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1620		Tranylcypromine	C9H11N	19493	Major		Inter Info	[56], [60], [1]
D1624		Trazodone	C19H22ClN5O	5533	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1647		Trimipramine	C20H26N2	5584	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D1658		Tryptophan	C11H12N2O2	6305	Major		Inter Info	[4], [5], [6], [7], [8], [10], [11], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D1689		Venlafaxine	C17H27NO2	5656	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [1], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0345		Citalopram	C20H21FN2O	2771	Moderate		Inter Info	[4], [5], [6], [7], [8], [10], [11], [12], [13], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0599		Escitalopram	C20H21FN2O	146570	Moderate		Inter Info	[4], [5], [6], [7], [8], [10], [11], [12], [13], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0676		Fluoxetine	C17H18F3NO	3386	Moderate		Inter Info	[4], [5], [6], [7], [8], [10], [11], [12], [13], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[4], [5], [6], [7], [8], [10], [11], [12], [13], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[73]
D1229		Paroxetine	C19H20FNO3	43815	Moderate		Inter Info	[4], [5], [6], [7], [8], [10], [11], [12], [13], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[4], [5], [6], [7], [8], [10], [11], [12], [13], [14], [15], [16], [17], [20], [21], [22], [23], [25], [26], [27], [29], [30], [31], [33], [34], [35], [41], [44], [46], [47], [48], [49], [50], [53], [54], [55], [57], [58], [59], [61], [64], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [83], [85], [86], [87]
	Increased risk of hyperpyrexia					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1046		Metoclopramide	C14H22ClN3O2	4168	Moderate		Inter Info	[297], [298]
	Increased risk of hypoglycemia					Drug Num: 20
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0013		Acetohexamide	C15H20N2O4S	1989	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166], [167], [17], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251]
D0325		Chlorpropamide	C10H13ClN2O3S	2727	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166], [167], [17], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251]
D0728		Glipizide	C21H27N5O4S	3478	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166], [167], [17], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166], [167], [17], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251]
D0807		Insulin aspart (aspart protamine)	C256H381N65O79S6	118984445	Moderate		Inter Info	[159], [215], [232]
D0808		Insulin aspart (aspart)	C256H381N65O79S6	118984445	Moderate		Inter Info	[159], [215], [232]
D0810		Insulin detemir	C267H402N64O76S6	16137271	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [289], [163], [164], [165], [166], [167], [17], [168], [169], [171], [172], [173], [175], [176], [177], [178], [180], [181], [182], [184], [186], [187], [188], [189], [190], [191], [192], [193], [194], [196], [199], [201], [202], [203], [206], [207], [209], [210], [211], [213], [290], [215], [291], [292], [220], [293], [294], [226], [228], [229], [230], [232], [234], [236], [238], [239], [243], [244], [245], [246], [295], [247], [248], [250], [251]
D0811		Insulin glargine	C267H404N72O78S6	118984454	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [289], [163], [164], [165], [166], [167], [17], [168], [169], [171], [172], [173], [175], [176], [177], [178], [180], [181], [182], [184], [186], [187], [188], [189], [190], [191], [192], [193], [194], [196], [199], [201], [202], [203], [206], [207], [209], [210], [211], [213], [290], [215], [291], [292], [220], [293], [294], [226], [228], [229], [230], [232], [234], [236], [238], [239], [243], [244], [245], [246], [295], [247], [248], [250], [251]
D0812		Insulin glulisine	C258H384N64O78S6	16136701	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [289], [163], [164], [165], [166], [167], [17], [168], [169], [171], [172], [173], [175], [176], [177], [178], [180], [181], [182], [184], [186], [187], [188], [189], [190], [191], [192], [193], [194], [196], [199], [201], [202], [203], [206], [207], [209], [210], [211], [213], [290], [215], [291], [292], [220], [293], [294], [226], [228], [229], [230], [232], [234], [236], [238], [239], [243], [244], [245], [246], [295], [247], [248], [250], [251]
D0813		Insulin human	C257H383N65O77S6	118984375	Moderate		Inter Info	[159], [215], [232]
D0814		Insulin human (inhalation, rapid acting)	C257H383N65O77S6	118984375	Moderate		Inter Info	[159], [215], [232]
D0815		Insulin human (isophane)	C257H383N65O77S6	118984375	Moderate		Inter Info	[159], [215], [232]
D0816		Insulin human (regular)	C257H383N65O77S6	118984375	Moderate		Inter Info	[159], [215], [232]
D0817		Insulin human (zinc extended)	C257H383N65O77S6	118984375	Moderate		Inter Info	[159], [215], [232]
D0819		Insulin lispro	C257H389N65O77S6	16132438	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [289], [163], [164], [165], [166], [167], [17], [168], [169], [171], [172], [173], [175], [176], [177], [178], [180], [181], [182], [184], [186], [187], [188], [189], [190], [191], [192], [193], [194], [196], [199], [201], [202], [203], [206], [207], [209], [210], [211], [213], [290], [215], [291], [292], [220], [293], [294], [226], [228], [229], [230], [232], [234], [236], [238], [239], [243], [244], [245], [246], [295], [247], [248], [250], [251]
D0820		Insulin lispro (protamine)	C257H389N65O77S6	16132438	Moderate		Inter Info	[159], [215], [232]
D1112		Nateglinide	C19H27NO3	5311309	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166], [167], [17], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251]
D1392		Repaglinide	C27H36N2O4	65981	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166], [167], [17], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251]
D0809		Insulin degludec	C274H411N65O81S6	118984462	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [289], [163], [164], [165], [166], [167], [17], [168], [169], [171], [172], [173], [175], [176], [177], [178], [180], [181], [182], [184], [186], [187], [188], [189], [190], [191], [192], [193], [194], [196], [199], [201], [202], [203], [206], [207], [209], [210], [211], [213], [290], [215], [291], [292], [220], [293], [294], [226], [228], [229], [230], [232], [234], [236], [238], [239], [243], [244], [245], [246], [295], [247], [248], [250], [251]
D1601		Tolazamide	C14H21N3O3S	5503	Moderate		Inter Info	[152], [153], [154], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [165], [166], [167], [17], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251]
	Increased risk of lowers seizure threshold					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1535		Tapentadol	C14H23NO	9838022	Major		Inter Info	[8], [16], [17], [20], [25], [27], [46], [49], [50], [53], [147], [78], [80]
D1616		Tramadol	C16H25NO2	33741	Major		Inter Info	[15], [148], [27], [46], [149], [49], [60], [150], [80]
Pharmacodynamic antagonistic effects
	Antagonize the effect of antihypertensive agents					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0743		Guanadrel	C10H19N3O2	38521	Moderate		Inter Info	[17], [20], [286], [287], [288], [53], [68], [75]
D0744		Guanethidine	C10H22N4	3518	Moderate		Inter Info	[17], [20], [286], [287], [288], [53], [68], [75]

References
1	Product Information. Emsam (selegiline). Bristol-Myers Squibb, Princeton, NJ.
2	Product Information. Tylenol with Codeine (acetaminophen-codeine). Janssen Pharmaceuticals, Raritan, NJ.
3	Zornberg GL, Hegarty JD "Adverse interaction between propoxyphene and phenelzine." Am J Psychiatry 150 (1993): 1270-1. [PMID: 8328578]
4	Alvine G, Black DW, Tsuang D "Case of delirium secondary to phenelzine/L-tryptophan combination." J Clin Psychiatry 51 (1990): 311. [PMID: 2365671]
5	Beasley CM Jr, Masica DN, Heiligenstein JH, Wheadon DE, Zerbe RL "Possible monoamine oxidase inhibitor-serotonin uptake inhibitor interaction: fluoxetine clinical data and preclinical findings." J Clin Psychopharmacol 13 (1993): 312-20. [PMID: 8227489]
6	Bem JL, Peck R "Dextromethorphan. An overview of safety issues." Drug Saf 7 (1992): 190-9. [PMID: 1503667]
7	Bhatara VS, Bandettini FC "Possible interaction between sertraline and tranylcypromine." Clin Pharm 12 (1993): 222-5. [PMID: 8491079]
8	Bodner RA, Lynch T, Lewis L, Kahn D "Serotonin syndrome." Neurology 45 (1995): 219-23. [PMID: 7854515]
9	Boyer EW, Shannon M "The serotonin syndrome." N Engl J Med 352 (2005): 1112-20. [PMID: 15784664]
10	Brannan SK, Talley BJ, Bowden CL "Sertraline and isocarboxazid cause a serotonin syndrome." J Clin Psychopharmacol 14 (1994): 144-5. [PMID: 8195456]
11	Brubacher JR, Hoffman RS, Lurin MJ "Serotonin syndrome from venlafaxine-tranylcypromine interaction." Vet Hum Toxicol 38 (1996): 358-61. [PMID: 8888541]
12	Cerner Multum, Inc. "Australian Product Information.".
13	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
14	Cetaruk EW, Aaron CK "Hazards of nonprescription medications." Emerg Med Clin North Am 12 (1994): 483-510. [PMID: 8187693]
15	Chan BSH, Graudins A, Whyte IM, Dawson AH, Braitberg G, Duggin GG "Serotonin syndrome resulting from drug interactions." Med J Aust 169 (1998): 523-5. [PMID: 9861909]
16	Corkeron MA "Serotonin syndrome - a potentially fatal complication of antidepressant therapy." Med J Aust 163 (1995): 481-2. [PMID: 7476638]
17	Darcy PF, Griffin JP "Interactions with drugs used in the treatment of depressive illness." Adverse Drug React Toxicol Rev 14 (1995): 211-31. [PMID: 8845455]
18	Dardennes RM, Even C, Ballon N, Bange F "Serotonin syndrome caused by a clomipramine-moclobemide interaction." J Clin Psychiatry 59 (1998): 382-3. [PMID: 9714270]
19	de la Fuente JR, Berlanga C, Leon-Andrade C "Mania induced by tricyclic-MAOI combination therapy in bipolar treatment-resistant disorder: case reports." J Clin Psychiatry 47 (1986): 40-1. [PMID: 3941059]
20	De Vita VT, Hahn MA, Oliverio VT "Monoamine oxidase inhibition by a new carcinostatic agent, n-isopropyl-a-(2-methylhydrazino)-p-toluamide (MIH). (30590)." Proc Soc Exp Biol Med 120 (1965): 561-5. [PMID: 4379192]
21	Diamond S "The use of sumatriptan in patients on monoamine oxidase inhibitors." Neurology 45 (1995): 1039-40. [PMID: 7783861]
22	Diamond S, Pepper BJ, Diamond ML, Freitag FG, Urban GJ, Erdemoglu AK "Serotonin syndrome induced by transitioning from phenelzine to venlafaxine: four patient reports." Neurology 51 (1998): 274-6. [PMID: 9674820]
23	Feighner JP, Boyer WF, Tyler DL, Neborsky RJ "Adverse consequences of fluoxetine-MAOI combination therapy." J Clin Psychiatry 51 (1990): 222-5. [PMID: 2347858]
24	Feighner JP, Herbstein J, Damlouji N "Combined MAOI, TCA, and direct stimulant therapy of treatment- resistant depression." J Clin Psychiatry 46 (1985): 206-9. [PMID: 3997787]
25	Fischer P "Serotonin syndrome in the elderly after antidepressive monotherapy." J Clin Psychopharmacol 15 (1995): 440-2. [PMID: 8748434]
26	Gardner DM, Lynd LD "Sumatriptan contraindications and the serotonin syndrome." Ann Pharmacother 32 (1998): 33-8. [PMID: 9475817]
27	Gillman PK "Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity." Br J Anaesth (2005):. [PMID: 16051647]
28	Goldberg LI "Monoamine oxidase inhibitors: adverse reactions and possible mechanisms." JAMA 190 (1964): 456-62. [PMID: 14197995]
29	Graber MA, Hoehns TB, Perry PJ "Sertraline-phenelzine drug interaction: a serotonin syndrome reaction." Ann Pharmacother 28 (1994): 732-5. [PMID: 7919561]
30	Graham PM, Ilett KF "Danger of MAOI therapy after fluoxetine withdrawal." Lancet 2 (1988): 1255-6. [PMID: 2903989]
31	Graham PM, Potter JM, Paterson J "Combination monoamine oxidase inhibitor/tricyclic antidepressants interaction." Lancet 2 (1982): 440. [PMID: 6124828]
32	Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):.
33	Heisler MA, Guidry JR, Arnecke B "Serotonin syndrome induced by administration of venlafaxine and phenelzine." Ann Pharmacother 30 (1996): 84. [PMID: 8773172]
34	Jacob JE, Wagner ML, Sage JI "Safety of selegiline with cold medications." Ann Pharmacother 37 (2003): 438-41. [PMID: 12639177]
35	Jimenez-Genchi A "Immediate switching from moclobemide to duloxetine may induce serotonin syndrome." J Clin Psychiatry 67 (2006): 1821-1822. [PMID: 17196070]
36	Joffe RT, Post RM, Uhde TW "Lack of pharmacokinetic interaction of carbamazepine with tranylcypromine." Arch Gen Psychiatry 42 (1985): 738. [PMID: 4015316]
37	Kay DW, Garside RF, Fahy TJ "A double-blind trial of phenelzine and amitriptyline in depressed out- patients. A possible differential effect of the drugs on symptoms." Br J Psychiatry 123 (1973): 63-7. [PMID: 4580991]
38	Keegan MT, Brown DR, Rabinstein AA "Serotonin syndrome from the interaction of cyclobenzaprine with other serotoninergic drugs." Anesth Analg 103 (2006): 1466-8. [PMID: 17122225]
39	Ketter TA, Post RM, Parekh PI, Worthington K "Addition of monoamine oxidase inhibitors to carbamazepine: preliminary evidence of safety and antidepressant efficacy in treatment-resistant depression." J Clin Psychiatry 56 (1995): 471-5. [PMID: 7559374]
40	Kline SS, Mauro LS, Scala-Bennett DM, Zick D "Serotonin syndrome versus neuroleptic malignant death syndrome as a cause of death." Clin Pharm 8 (1989): 510-4. [PMID: 2568897]
41	Klysner R, Larsen JK, Sorensen P, Hyllested M, Pedersen BD "Toxic interaction of venlafaxine and isocarboxazide." Lancet 346 (1995): 1298-9. [PMID: 7475741]
42	Lader M "Combined use of tricyclic antidepressants and monoamine oxidase inhibitors." J Clin Psychiatry 44 (1983): 20-4. [PMID: 6355073]
43	Lefebvre H, Noblet C, Morre N, Wolf LM "Pseudo-phaeochromocytoma after multiple drug interactions involving the selective monoamine oxidase inhibitor selegiline." Clin Endocrinol (Oxf) 42 (1995): 95-8. [PMID: 7889639]
44	Levy AB, Bucher P, Votolato N "Myoclonus, hyperreflexia and diaphoresis in patients on phenelzine- tryptophan combination treatment." Can J Psychiatry 30 (1985): 434-6. [PMID: 4063940]
45	Lydiard RB, White D, Harvey B, Taylor A "Lack of pharmacokinetic interaction between tranylcypromine and carbamazepine." J Clin Psychopharmacol 7 (1987): 360. [PMID: 3680612]
46	Martin TG "Serotonin syndrome." Ann Emerg Med 28 (1996): 520-6. [PMID: 8909274]
47	Mathew NT, Tietjen GE, Lucker C "Serotonin syndrome complicating migraine pharmacotherapy." Cephalalgia 16 (1996): 323-7. [PMID: 8869767]
48	Miller LG "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions." Arch Intern Med 158 (1998): 2200-11. [PMID: 9818800]
49	Mills KC "Serotonin syndrome: A clinical update." Crit Care Clin 13 (1997): 763. [PMID: 9330840]
50	Nierenberg DW, Semprebon M "The central nervous system serotonin syndrome." Clin Pharmacol Ther 53 (1993): 84-8. [PMID: 8257462]
51	Otte W, Birkenhager TK, van den Broek WW "Fatal interaction between tranylcypromine and imipramine." Eur Psychiatry 18 (2003): 264-5. [PMID: 12927331]
52	Pascual J, Combarros O, Berciano J "Partial status epilepticus following single low dose of chlorimipramine in a patient on MAO-inhibitor treatment." Clin Neuropharmacol 10 (1987): 565-7. [PMID: 3427564]
53	Pettinger WA, Soyangco FG, Oates JA "Inhibition of monoamine oxidase in man by furazolidone." Clin Pharmacol Ther 9 (1968): 442-7. [PMID: 5655478]
54	Phillips SD, Ringo P "Phenelzine and venlafaxine interaction." Am J Psychiatry 152 (1995): 1400-1. [PMID: 7653704]
55	Pope HG Jr, Jonas JM, Hudson JI, Kafka MP "Toxic reactions to the combination of monoamine oxidase inhibitors and tryptophan." Am J Psychiatry 142 (1985): 491-2. [PMID: 3976924]
56	Product Information. Azilect (rasagiline). Teva Pharmaceuticals USA, North Wales, PA.
57	Product Information. Cymbalta (duloxetine). Lilly, Eli and Company, Indianapolis, IN.
58	Product Information. D.H.E. 45 (dihydroergotamine). Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
59	Product Information. Effexor (venlafaxine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
60	Product Information. Eldepryl (selegiline). Somerset Pharmaceuticals Inc, Tampa, FL.
61	Product Information. Fetzima (levomilnacipran). Forest Pharmaceuticals, St. Louis, MO.
62	Product Information. Flexeril (cyclobenzaprine). Merck & Co, Inc, West Point, PA.
63	Product Information. Furoxone (furazolidone). Roberts Pharmaceutical Corporation, Eatontown, NJ.
64	Product Information. Manerix (moclobemide). Hoffmann-La Roche Limited, Mississauga, IA.
65	Product Information. Marplan (isocarboxazid) Roche Laboratories, Nutley, NJ.
66	Product Information. Matulane (procarbazine). Roche Laboratories, Nutley, NJ.
67	Product Information. Methylene Blue (methylene blue). American Regent Laboratories Inc, Shirley, NY.
68	Product Information. Nardil (phenelzine). Parke-Dvis, Morris Plains, NJ.
69	Product Information. Parnate (tranylcypromine). SmithKline Beecham, Philadelphia, PA.
70	Product Information. Pristiq (desvenlafaxine). Wyeth Laboratories, Philadelphia, PA.
71	Product Information. Savella (milnacipran). Forest Pharmaceuticals, St. Louis, MO.
72	Product Information. Viibryd (vilazodone). Trovis Pharmaceuticals LLC, New Haven, CT.
73	Product Information. Xadago (safinamide). US WorldMeds LLC, Louisville , KY.
74	Rivers N, Horner B "Possible lethal reaction between nardil and dextromethorphan." Can Med Assoc J 103 (1970): 85. [PMID: 20311659]
75	Schulz R, Antonin KH, Hoffmann E, et al "Tyramine kinetics and pressor sensitivity during monoamine oxidase inhibition by selegiline." Clin Pharmacol Ther 46 (1989): 528-36. [PMID: 2510962]
76	Sovner R, Wolfe J "Interaction between dextromethorphan and monoamine oxidase inhibitor therapy with isocarboxazid ." N Engl J Med 319 (1988): 1671. [PMID: 3200285]
77	Spiker DG, Pugh DD "Combining tricyclic and monoamine oxidase inhibitor antidepressants." Arch Gen Psychiatry 33 (1976): 828-30. [PMID: 942286]
78	Staufenberg EF, Tantam D "Malignant hyperpyrexia syndrome in combined treatment." Br J Psychiatry 154 (1989): 577-8. [PMID: 2590798]
79	Sternbach H "Danger of MAOI therapy after fluoxetine withdrawal." Lancet 2 (1988): 850-1. [PMID: 2902292]
80	Sternbach H "The serotonin syndrome." Am J Psychiatry 148 (1991): 705-13. [PMID: 2035713]
81	Suchowersky O, deVries JD "Interaction of fluoxetine and selegiline." Can J Psychiatry 35 (1990): 571-2. [PMID: 2119876]
82	Tackley RM, Tregaskis B "Fatal disseminated intravascular coagulation following a monoamine oxidase inhibitor/tricyclic interaction." Anaesthesia 42 (1987): 760-3. [PMID: 3631476]
83	Thomas JM, Rubin EH "Case report of a toxic reaction from a combination of tryptophan and phenelzine." Am J Psychiatry 141 (1984): 281-3. [PMID: 6691495]
84	Waghray SN, Francis K "Epilepsy as an adverse reaction to combined therapy of MAOIs and tricyclics." J R Soc Med 77 (1984): 346. [PMID: 6425500]
85	Weiner LA, Smythe M, Cisek J "Serotonin syndrome secondary to phenelzine-venlafaxine interaction." Pharmacotherapy 18 (1998): 399-403. [PMID: 9545162]
86	White K, Pistole T, Boyd JL "Combined monoamine oxidase inhibitor-tricyclic antidepressant treatment: a pilot study." Am J Psychiatry 137 (1980): 1422-5. [PMID: 7435677]
87	White K, Simpson G "Combined MAOI-tricyclic antidepressant treatment: a reevaluation." J Clin Psychopharmacol 1 (1981): 264-82. [PMID: 7037873]
88	Wright SP "Hazards with monoamine-oxidase inhibitors: a persistent problem." Lancet 1 (1978): 284-5. [PMID: 74715]
89	Yatham LN, Barry S, Mobayed M, Dinan TG "Is the carbamazepine-phenelzine combination safe?." Am J Psychiatry 147 (1990): 367. [PMID: 2309956]
90	Zetin M "Combined use of trimipramine and phenelzine in depression." J Nerv Ment Dis 170 (1982): 246-7. [PMID: 7062012]
91	Ban TA "Drug interactions with psychoactive drugs." Dis Nerv Syst 36 (1975): 164-6. [PMID: 1116424]
92	Boakes AJ, Laurence DR, Teoh PC, Barar FS, Benedikter LT, Prichard BN "Interactions between sympathomimetic amines and antidepressant agents in man." Br Med J 1 (1973): 311-5. [PMID: 4685619]
93	Boakes AJ, Laurence DR, Teoh PC, Barar FS, Benedikter LT, Pritchard BN "Interactions between sympathomimetic amines and antidepressant agents in man." Br Med J 1 (1973): 311-5. [PMID: 4685619]
94	Cuthbert MF, Greenberg MP, Morley SW "Cough and cold remedies: a potential danger to patients on monoamine oxidase inhibitors." Br Med J 1 (1969): 404-6. [PMID: 5763957]
95	FISCHER E, ORLANDO J, LUDMER RL. INFLUENCIA DE METILANFETAMINA, IPRONIACIDA Y TRANILCIPROMINA SOBRE LA DEPRESI'ON PSICOMOTORA ADRENAL'INICA [EFFECT OF METHYLAMPHETAMINE, IPRONIAZID AND TRANYLCYPROMINE ON ADRENALINE PSYCHOMOTOR DEPRESSION]. Prensa Med Argent. 1964;51:1538-1540. [PMID: 14272082]
96	Davies B, Bannister R, Sever P "Pressor amines and monoamine-oxidase inhibitors for treatment of postural hypotension in autonomic failure: limitations and hazards." Lancet 1 (1978): 172-5. [PMID: 74603]
97	Elis J, Laurence DR, Mattie H, Prichard BN "Modification by monoamine oxidase inhibitors of the effect of some sympathomimetics on blood pressure." Br Med J 2 (1967): 75-8. [PMID: 6020852]
98	Goulet JP, Perusse R, Turcotte JY "Contraindications to vasoconstrictors in dentistry: Part III. Pharmacologic interactions." Oral Surg Oral Med Oral Pathol 74 (1992): 692-7. [PMID: 1359489]
99	Harrison WM, McGrath PJ, Stewart JW, Quitkin F "MAOIs and hypertensive crises: the role of OTC drugs." J Clin Psychiatry 50 (1989): 64-5. [PMID: 2464583]
100	Horler AR, Wynne NA "Hypertensive crisis due to pargyline and metaraminol." Br Med J 5459 (1965): 460-1. [PMID: 14314914]
101	Humberstone PM "Hypertension from cold remedies." Br Med J 1 (1969): 846. [PMID: 5813090]
102	Krisko I, Lewis E, Johnson JE "Severe hyperpyrexia due to tranylcypromine-amphetamine toxicity." Ann Intern Med 70 (1969): 559-64. [PMID: 5775035]
103	Markowitz JS, Patrick KS "Pharmacokinetic and pharmacodynamic drug interactions in the treatment of attention-deficit hyperactivity disorder." Clin Pharmacokinet 40 (2001): 753-72. [PMID: 11707061]
104	Mason AM, Buckle RM ""Cold" cures and monoamine-oxidase inhibitors." Br Med J 1 (1969): 845-6. [PMID: 5813089]
105	Product Information. Vyvanse (lisdexamfetamine). Shire US Inc, Florence, KY.
106	Schildkraut JJ, Klerman GL, Friend DG, Greenblatt M "Biochemical and pressor effects of oral d,l-dihydroxyphenylalanine in patients pretreated with antidepressant drugs." Ann N Y Acad Sci 107 (1963): 1005-15. [PMID: 13991689]
107	Sjoqvist F "Psychotropic drugs (2) interaction between monoamine oxidase (MAO) inhibitors and other substances." Proc R Soc Med 58 (1965): 967-78. [PMID: 4952963]
108	Smookler S, Barmudez AJ "Hypertensive crisis resulting from an MAO inhibitor and an over-the counter appetite suppressant." Ann Emerg Med 11 (1982): 482-4. [PMID: 7114595]
109	Smookler S, Bermudez AJ "Hypertensive crisis resulting from an MAO inhibitor and an over-the-counter appetite suppressant." Ann Intern Med 11 (1982): 482-4. [PMID: 7114595]
110	Product Information. Iopidine (apraclonidine). Alcon Laboratories Inc, Fort Worth, TX.
111	James WA, Lippmann S "Bupropion: overview and prescribing guidelines in depression." South Med J 84 (1991): 222-4. [PMID: 1899294]
112	Product Information. Wellbutrin (bupropion). Glaxo Wellcome, Research Triangle Park, NC.
113	Product Information. Zyvox (linezolid) Pharmacia and Upjohn, Kalamazoo, MI.
114	Browne B, Linter S "Monoamine oxidase inhibitors and narcotic analgesics: a critical review of the implications for treatment." Br J Psychiatry 151 (1987): 210-2. [PMID: 2891392]
115	Das PK, Warkentin DI, Hewko R, Forrest DL "Serotonin syndrome after concomitant treatment with linezolid and meperidine." Clin Infect Dis 46 (2008): 264-5. [PMID: 18171260]
116	Evans-Prosser CD "The use of pethidine and morphine in the presence of monoamine oxidase inhibitors." Br J Anaesth 40 (1968): 279-82. [PMID: 5654977]
117	Garbutt JC "Potentiation of propoxyphene by phenelzine." Am J Psychiatry 144 (1987): 251-2. [PMID: 2949636]
118	Gillman PK "Possible serotonin syndrome with moclobemide and pethidine." Med J Aust 162 (1995): 554. [PMID: 7776924]
119	Insler SR, Kraenzler EJ, Licina MG, Savage RM, Starr NJ "Cardiac surgery in a patient taking monoamine oxidase inhibitors - an adverse fentanyl reaction." Anesth Analg 78 (1994): 593-7. [PMID: 8109782]
120	Michaels I, Serrins M, Shier NQ, Barash PG "Anesthesia for cardiac surgery in patients receiving monoamine oxidase inhibitors." Anesth Analg 63 (1984): 1041-4. [PMID: 6333833]
121	Noble WH, Baker A "MAO inhibitors and coronary artery surgery: a patient death." Can J Anaesth 39 (1992): 1061-6. [PMID: 1464133]
122	Product Information. Actiq (fentanyl). Abbott Pharmaceutical, Abbott Park, IL.
123	Product Information. Demerol (meperidine). Sanofi Winthrop Pharmaceuticals, New York, NY.
124	Product Information. Duragesic Transdermal System (fentanyl). Janssen Pharmaceutica, Titusville, NJ.
125	Product Information. Meperidine Hydrochloride Injection, USP (meperidine) Astra-Zeneca Pharmaceuticals, Wilmington, DE.
126	Starr C "Interaction between pethidine and selegiline." Lancet 337 (1991): 554. [PMID: 1671914]
127	Upton R, Graff A, Williamson E, et al. "American Herbal Pharmacopoeia and Therapeutic Compendium. Monograph printed in Herbalgram." Herbalgram 40 (1997): 1-38(monograph).
128	Vigran IM "Dangerous potentiation of meperidine hydrochloride by pargyline hydrochloride." JAMA 187 (1964): 953-4. [PMID: 14100156]
129	Weiner AL "Meperidine as a potential cause of serotonin syndrome in the emergency department." Acad Emerg Med 6 (1999): 156-8. [PMID: 10051909]
130	Youssef MS, Wilkinson PA "Epidural fentanyl and monoamine oxidase inhibitors." Anaesthesia 43 (1988): 210-2. [PMID: 3364639]
131	Zornberg GL, Bodkin JA, Cohen BM "Severe adverse interaction between pethidine and selegiline." Lancet 337 (1991): 246. [PMID: 1670882]
132	Paladino JA "Linezolid: an oxazolidinone antimicrobial agent." Am J Health Syst Pharm 59 (2002): 2413-25. [PMID: 12503340]
133	FDA. U.S. Food and Drug Administration "FDA Drug Safety Communication: Serious CNS reactions possible when linezolid (Ayvox) is given to patients taking certain psychiatric medications.".
134	Paykel ES "Hallucinosis on combined methyldopa and pargyline." Br Med J 1 (1966): 803. [PMID: 5910115]
135	Product Information. Aldomet (methyldopa). Merck & Co, Inc, West Point, PA.
136	van Rossum JM "Potential danger of monoamineoxidase inhibitors and a-methyldopa." Lancet 1 (1963): 950-1. [PMID: 13975251]
137	van Rossum JM, Hurkmans JA "Reversal of the effect of a-Methyldopa by monamine oxidase inhibitors." J Pharm Pharmacol 15 (1963): 493-9. [PMID: 14059015]
138	Product Information. Orladeyo (berotralstat). BioCryst Pharmaceuticals Inc, Durham, NC.
139	Product Information. Austedo (deutetrabenazine). Teva Pharmaceuticals USA, North Wales, PA.
140	Product Information. Nitoman (tetrabenazine). Cambridge Laboratories Ltd, Wallsend, Tyne & Wear, .
141	Product Information. Xenazine (tetrabenazine). Prestwick Pharmaceuticals Inc, Washington DC, VA.
142	Product Information. Spravato (esketamine). Janssen Pharmaceuticals, Titusville, NJ.
143	Product Information. Azedra (iobenguane I-131). Progenics Pharmaceuticals, Inc., New York, NY.
144	Product Information. Zeposia (ozanimod). Celgene Corporation, Summit, NJ.
145	Product Information. Sunosi (solriamfetol). Jazz Pharmaceuticals, Palo Alto, CA.
146	Product Information. Ingrezza (valbenazine). Neurocrine Biosciences, Inc., San Diego, CA.
147	Product Information. Nucynta (tapentadol). PriCara Pharmaceuticals, Raritan, NJ.
148	Egberts AC, ter Borg J, Brodie-Meijer CC "Serotonin syndrome attributed to tramadol addition to paroxetine therapy." Int Clin Psychopharmacol 12 (1997): 181-2. [PMID: 9248876]
149	Mason BJ, Blackburn KH "Possible serotonin syndrome associated with tramadol and sertraline coadministration." Ann Pharmacother 31 (1997): 175-7. [PMID: 9034418]
150	Product Information. Ultram (tramadol). McNeil Pharmaceutical, Raritan, NJ.
151	Kronig MH, Roose SP, Walsh BT, Woodring S, Glassman AH "Blood pressure effects of phenelzine." J Clin Psychopharmacol 3 (1983): 307-10. [PMID: 6630590]
152	Abad S, Moachon L, Blanche P, Bavoux F, Sicard D, Salmon-Ceron D "Possible interaction between glicazide, fluconazole and sulfamethoxazole resulting in severe hypoglycaemia." Br J Clin Pharmacol 52 (2001): 456-7. [PMID: 11678792]
153	Ahmad S "Drug interaction induces hypoglycemia." J Fam Pract 40 (1995): 540-1. [PMID: 7775905]
154	Ahmad S "Gemfibrozil: interaction with glyburide." South Med J 84 (1991): 102. [PMID: 1898783]
155	Aleyassine H, Gardiner RJ "Dual action of antidepressant drugs (MAO inhibitors) on insulin release." Endocrinology 96 (1975): 702-10. [PMID: 1090438]
156	Aleyassine H, Lee SH "Inhibition of insulin release by substrates and inhibitors of monoamine oxidase." Am J Physiol 222 (1972): 565-9. [PMID: 5022664]
157	Almirall J, Montoliu J, Torras A, Revert L "Propoxyphene-induced hypoglycemia in a patient with chronic renal failure." Nephron 53 (1989): 273-5. [PMID: 2797348]
158	Arauz-Pacheco C, Ramirez LC, Rios JM, Raskin P "Hypoglycemia induced by angiotensin-converting enzyme inhibitors in patients with non-insulin-dependent diabetes receiving sulfonylurea therapy." Am J Med 89 (1990): 811-3. [PMID: 2123605]
159	Asplund K, Wiholm BE, Lithner F "Glibenclamide-associated hypoglycaemia: a report on 57 cases." Diabetologia 24 (1983): 412-7. [PMID: 6411511]
160	Baciewicz AM, Swafford WB Jr "Hypoglycemia induced by the interaction of chlorpropamide and co-trimoxazole." Drug Intell Clin Pharm 18 (1984): 309-10. [PMID: 6609055]
161	Barbato M "Another problem with Kinidin." Med J Aust 141 (1984): 685. [PMID: 6436654]
162	Baron SH "Salicylates as hypoglycemic agents." Diabetes Care 5 (1982): 64-71. [PMID: 6754304]
163	Cacoub P, Deray G, Baumelou A, Grimaldi A, Soubrie C, Jacobs C "Disopyramide-induced hypoglycemia: case report and review of the literature." Fundam Clin Pharmacol 3 (1989): 527-35. [PMID: 2691378]
164	Cattaneo AG, Caviezel F, Pozza G "Pharmacological interaction between tolbutamide and acetylsalicylic acid: study on insulin secretion in man." Int J Clin Pharmacol Ther Toxicol 28 (1990): 229-34. [PMID: 2198232]
165	Christensen LK, Hansen JM, Kristensen M "Sulphaphenazole-induced hypoglycemic attacks in tolbutamide-treated diabetics." Lancet 2 (1963): 1298-301. [PMID: 14071924]
166	Cooper AJ, Ashcroft G "Potentiation of insulin hypoglycaemia by M.A.O.I. antidepressant drugs." Lancet 1 (1966): 407-9. [PMID: 4159787]
167	Croxson MS, Shaw DW, Henley PG, Gabriel HDLL "Disopyramide-induced hypoglycaemia and increased serum insulin." N Z Med J July (1987): 407-8. [PMID: 3330586]
168	Daubresse JC, Daigneux D, Bruwier M, Luyckx A, Lefebvre PJ "Clofibrate and diabetes control in patients treated with oral hypoglycaemic agents." Br J Clin Pharmacol 7 (1979): 599-603. [PMID: 380614]
169	Daubresse JC, Luyckx AS, Lefebvre PJ "Potentiation of hypoglycemic effect of sulfonylureas by clofibrate." N Engl J Med 294 (1976): 613. [PMID: 1246250]
170	David DS, Steere AC Jr, Pi-Sunyer XF, Sakai S, Clark SB "Aspirin-induced hypoglycaemia in a patient on haemodialysis." Lancet 2 (1971): 1092-3. [PMID: 4106934]
171	Davis TM, Karbwang J, Looareesuwan S, et al "Comparative effects of quinine and quinidine on glucose metabolism in healthy volunteers." Br J Clin Pharmacol 30 (1990): 397-403. [PMID: 2223418]
172	de Salcedo I, Gorringe AL, Silva JL, Santos JA "Gemfibrozil in a group of diabetics." Proc R Soc Med 69 (1976): 64-70. [PMID: 1019155]
173	Deeg MA, Lipkin EW "Hypoglycemia associated with the use of fluoxetine." West J Med 164 (1996): 262-3. [PMID: 8775944]
174	Diwan PV, Sastry MS, Satyanarayana NV "Potentiation of hypoglycemic response of glibenclamide by piroxicam in rats and humans." Indian J Exp Biol 30 (1992): 317-9. [PMID: 1459600]
175	Feher MD, Amiel S "ACE inhibitors and hypoglycaemia." Lancet 346 (1995): 125-6. [PMID: 7603199]
176	Feldman JM, Chapman B "Monoamine oxidase inhibitors: nature of their interaction with rabbit pancreatic islets to alter insulin secretion." Diabetologia 11 (1975): 487-94. [PMID: 1107123]
177	Ferrari C, Fressati S, Romussi M, et al. "Effects of short-term clofibrate administration on glucose tolerance and insulin secretion in patients with chemical diabetes or hypertriglyceridemia." Metabolism 26 (1977): 129-39. [PMID: 834147]
178	Ferriere M, Lachkar H, Richard JL, Bringer J, Orsetti A, Mirouze J "Captopril and insulin sensitivity." Ann Intern Med 102 (1985): 134-5. [PMID: 3881067]
179	Field JB, Ohta M, Boyle C, Remer A "Potentiation of acetohexamide hypoglycemia by phenylbutazone." N Engl J Med 277 (1967): 889-94. [PMID: 6061822]
180	Fogari R, Zoppi A, Corradi L, Pierangelo L, Mugellini A, Lusardi P "Comparative effects of lisinopril and losartan on insulin sensitivity in the treatment of non diabetic hypertension." Br J Clin Pharmacol 46 (1998): 467-71. [PMID: 9833600]
181	Giugliano D, Ceriello A, Saccomanno F, et al "Effects of salicylate, tolbutamide, and prostaglandin E2 on insulin responses to glucose in noninsulin-dependent diabetes mellitus." J Clin Endocrinol Metab 61 (1985): 160-6. [PMID: 3923028]
182	Goldberg IJ, Brown LK, Rayfield EJ "Disopyramide (norpace)-induced hypoglycemia." Am J Med 69 (1980): 463-6. [PMID: 6998294]
183	Harris EL "Adverse reactions to oral antidiabetic agents." Br Med J 3 (1971): 29-30. [PMID: 5091891]
184	Harrison LC, King-Roach A, Martin FI, Melick RA "The effect of fenfluramine on insulin binding and on basal and insulin-stimulated oxidation of 1-C-glucose by human adipose tissue." Postgrad Med J 51 Suppl 1 (1975): 110-4. [PMID: 1219664]
185	Hartmann D, Korn A, Komjati M, Heinz G, Haefelfinger P, Defoin R, Waldhausl WK "Lack of effect of tenoxicam on dynamic responses to concurrent oral doses of glucose and glibenclamide." Br J Clin Pharmacol 30 (1990): 245-52. [PMID: 2119677]
186	Hayashi S, Horie M, Tsuura Y, Ishida H, Okada Y, Seino Y, Sasayama S "Disopyramide blocks pancreatic ATP-sensitive K+ channels and enhances insulin release." Am J Physiol 265 (1993): c337-42. [PMID: 8368263]
187	Hekimsoy Z, Biberoglu S, Comlekci A, Tarhan O, Mermut C, Biberoglu K "Trimethoprim/sulfamethoxazole-induced hypoglycemia in a malnourished patient with severe infection." Eur J Endocrinol 136 (1997): 3046. [PMID: 9100556]
188	Hellman B "Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells." Metabolism 23 (1974): 839-46. [PMID: 4212254]
189	Herings RMC, Deboer A, Stricker BHC, Leufkens HGM, Porsius A "Hypoglycaemia associated with use of inhibitors of angiotensin converting enzyme." Lancet 345 (1995): 1195-8. [PMID: 7739305]
190	Hundal RS, Petersen KF, Mayerson AB, et al "Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes." J Clin Invest 109 (2002): 1321-6. [PMID: 12021247]
191	Iida H, Morita T, Suzuki E, Iwasawa K, Toyooka T, Nakajima T "Hypoglycemia induced by interaction between clarithromycin and disopyramide." Jpn Heart J 40 (1999): 91-6. [PMID: 10370402]
192	Johnson J, Dobmeier M "Symptomatic hypoglycemia secondary to a glipizide-trimethoprim/sulfamethoxazole drug interaction." DICP 24 (1990): 250-1. [PMID: 2316232]
193	Johnson JA, Kappel JE, Sharif MN "Hypoglycemia secondary to trimethoprim/sulfamethoxazole administration in a renal transplant patient." Ann Pharmacother 27 (1993): 304-6. [PMID: 8453166]
194	Konttinen A, Kuisma I, Ralli R, Pohjola S, Ojala K "The effect of gemfibrozil on serum lipids in diabetic patients." Ann Clin Res 11 (1979): 240-5. [PMID: 398183]
195	Kradjan WA, Witt DM, Opheim KE, Wood FC "Lack of interaction between glipizide and co-trimoxazole." J Clin Pharmacol 34 (1994): 997-1002. [PMID: 7836551]
196	Kubacka RT, Antla EJ, Juhl RP, Welshman IR "Effects of aspirin and ibuprofen on the pharmacokinetics and pharmacodynamics of glyburide in healthy subjects." Ann Pharmacother 30 (1996): 20-6. [PMID: 8773160]
197	Lozada A, Dujovne CA "Drug interactions with fibric acids." Pharmacol Ther 63 (1994): 163-76. [PMID: 7809177]
198	Lumholtz B, Siersbaek-Nielsen K, Skovsted L, Kampmann J, Hansen JM "Sulfamethizole-induced inhibition of diphenylhydantoin, tolbutamide, and warfarin metabolism." Clin Pharmacol Ther 17 (1975): 731-4. [PMID: 1139863]
199	Morris AD, Newton RW, Boyle DI, et al. "ACE inhibitor use is associated with hospitalization for severe hypoglycemia in patients with diabetes." Diabetes Care 20 (1997): 1363-7. [PMID: 9283780]
200	Morrison PJ, Rogers HJ, Spector RG, Bradbrook ID, John VA "Effect of pirprofen on glibenclamide kinetics and response." Br J Clin Pharmacol 14 (1982): 123-6. [PMID: 6809024]
201	Murakami K, Nambu S, Koh H, Kobayashi M, Shigeta Y "Clofibrate enhances the affinity of insulin receptors in non-insulin dependent diabetes mellitus." Br J Clin Pharmacol 17 (1984): 89-91. [PMID: 6362704]
202	Nakabayashi H, Ito T, Igawa T, Hiraiwa Y, Imamura T, Seta T, Kawato M, Usukura N, Takeda R "Disopyramide induces insulin secretion and plasma glucose diminution: studies using the in situ canine pancreas." Metabolism 38 (1989): 179-83. [PMID: 2643753]
203	Nappi JM, Dhanani S, Lovejoy JR, VanderArk C "Severe hypoglycemia associated with disopyramide." West J Med 138 (1983): 95-7. [PMID: 6404062]
204	Niemi M, Backman JT, Neuvonen M, Laitila J, Neuvonen PJ, Kivisto KT "Effects of fluconazole and fluvoxamine on the pharmacokinetics and pharmacodynamics of glimepiride." Clin Pharmacol Ther 69 (2001): 194-200. [PMID: 11309547]
205	Nikkila EA, Ylikahri R, Huttunen JK "Gemfibrozil: effect on serum lipids, lipoproteins, postheparin plasma lipase activities and glucose tolerance in primary hypertriglyceridaemia." Proc R Soc Med 69 (1976): 58-63. [PMID: 190608]
206	Paolisso G, Balbi V, Gambardella A, Varricchio G, Tortoriello R, Saccomanno F, Amato L, Varricchio M "Lisinopril administration improves insulin action in aged patients with hypertension." J Hum Hypertens 9 (1995): 541-6. [PMID: 7562882]
207	Pestell RG, Crock PA, Ward GM, Alford FP, Best JD "Fenfluramine increases insulin action in patients with NIDDM." Diabetes Care 12 (1989): 252-8. [PMID: 2495916]
208	Petitpierre B, Perrin L, Rudhardt M, et al "Behaviour of chlorpropamide in renal insufficiency and under the effect of associated drug therapy." Int J Clin Pharmacol 6 (1972): 120-4. [PMID: 4638970]
209	Phillips AF, Matty PJ, Porte PJ, Raye JR "Inhibition of glucose-induced insulin secretion by indomethacin and sodium salicylate in the fetal lamb." Am J Obstet Gynecol 148 (1984): 481-7. [PMID: 6364813]
210	Phillips RE, Looareesuwan S, White NJ, et al "Hypoglycaemia and antimalarial drugs: quinidine and release of insulin." Br Med J 292 (1986): 1319-21. [PMID: 3085830]
211	Pollak PT, Mukherjee SD, Fraser AD "Sertraline-induced hypoglycemia." Ann Pharmacother 35 (2001): 1371-4. [PMID: 11724085]
212	Pond SM, Birkett DJ, Wade DN "Mechanisms of inhibition of tolbutamide metabolism: phenylbutazone, oxyphenbutazone, sulfaphenazole." Clin Pharmacol Ther 22 (1977): 573-9. [PMID: 913025]
213	Prince RL, Larkins RG, Alford FP "The effect of acetylsalicylic acid on plasma glucose and the response of glucose regulatory hormones to intravenous glucose and arginine in insulin treated diabetics and normal subjects." Metabolism 30 (1981): 293-8. [PMID: 7010074]
214	Product Information. Amaryl (glimepiride). Hoechst Marion-Roussel Inc, Kansas City, MO.
215	Product Information. Apidra (insulin glulisine). Aventis Pharmaceuticals, Bridgewater, NJ.
216	Product Information. Diabeta (glyburide). Hoechst Marion-Roussel Inc, Kansas City, MO.
217	Product Information. Diabinese (chlorpropamide). Pfizer US Pharmaceuticals, New York, NY.
218	Product Information. Dymelor (acetohexamide) Lilly, Eli and Company, Indianapolis, IN.
219	Product Information. Glucotrol (glipizide). Pfizer US Pharmaceuticals, New York, NY.
220	Product Information. Increlex (mecasermin). Tercica Inc, Brisbane, CA.
221	Product Information. Micronase (glyburide). Pharmacia and Upjohn, Kalamazoo, MI.
222	Product Information. Orinase (tolbutamide) Pharmacia and Upjohn, Kalamazoo, MI.
223	Product Information. Prandin (repaglinide). Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.
224	Product Information. Starlix (nateglinide) Novartis Pharmaceuticals, East Hanover, NJ.
225	Product Information. Tolinase (tolazamide) Pharmacia and Upjohn, Kalamazoo, MI.
226	Quevedo SF, Krauss DS, Chazan JA, et al "Fasting hypoglycemia secondary to disopyramide therapy." JAMA 245 (1981): 2424. [PMID: 6785461]
227	Ravic M, Johnston A, Turner P "Clinical pharmacological studies of some possible interactions of lornoxicam with other drugs." Postgrad Med J 66 (1990): s30-4. [PMID: 2126624]
228	Richardson T, Foster J, Mawer GE "Enhancement by sodium salicylate of the blood glucose lowering effect of chlorpropamide-drug interaction or summation of similar effects." Br J Clin Pharmacol 22 (1986): 43-8. [PMID: 3527244]
229	Rubin M, Zakheim B, Pitchumoni C "Disopyramide-induced profound hypoglycemia." N Y State J Med July,Aug,S (1983): 1057-8. [PMID: 6579404]
230	Salmela PI, Sotaniemi EA, Viikari J, et al "Fenfluramine therapy in non-insulin-dependent diabetic patients effects on body weight, glucose homeostasis, serum lipoproteins, and antipyrine metabolism." Diabetes Care 4 (1981): 535-40. [PMID: 6751729]
231	Sawka AM, Burgart V, Zimmerman D "Loss of awareness of hypoglycemia temporally associated with selective serotonin reuptake inhibitors." Diabetes Care 24 (2001): 1845-6. [PMID: 11574457]
232	Semel JD, Wortham E, Karl DM "Fasting hypoglycemia associated with disopyramide." Am Heart J 106 (1983): 1160-1. [PMID: 6356848]
233	Shah SJ, Bhandarkar SD, Satoskar RS "Drug interaction between chlorpropamide and non-steroidal anti-flammatory drugs, ibuprofen and phenylbutazone." Int J Clin Pharmacol Ther Toxicol 22 (1984): 470-2. [PMID: 6500764]
234	Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V "Variable effects of American ginseng: a batch of American ginseng (Panax quinquefolius L.) with a depressed ginsenoside profile does not affect postprandial glycemia." Eur J Clin Nutr 57 (2003): 243-8. [PMID: 12571655]
235	Sjoberg S, Wiholm BE, Gunnarsson R, Emilsson H, Thunberg E, Christenson I, Ostman J "Lack of pharmacokinetic interaction between glibenclamide and trimethoprim-sulphamethoxazole." Diabet Med 4 (1987): 245-7. [PMID: 2956028]
236	Slade IH, and Iosefa RN "Fatal hypoglycemic coma from the use of tolbutamide in elderly patients: report of two cases." J Am Geriatr Soc 15 (1967): 948-50. [PMID: 6046558]
237	Sone H, Takahashi A, Yamada N "Ibuprofen-related hypoglycemia in a patient receiving sulfonylurea." Ann Intern Med 134 (2001): 344. [PMID: 11182854]
238	Storlien LH, Thorburn AW, Smythe GA, Jenkins AB, Chisholm DJ, Kraegen EW "Effect of d-fenfluramine on basal glucose turnover and fat-feeding-induced insulin resistance in rats." Diabetes 38 (1989): 499-503. [PMID: 2647557]
239	Strathman I, Schubert EN, Cohen A, Nitzberg DM "Hypoglycemia in patients receiving disopyramide phosphate." Drug Intell Clin Pharm 17 (1983): 635-8. [PMID: 6413187]
240	Tannenbaum H, Anderson LG, Soeldner JS "Phenylbutazone-tolbutamide drug interaction." N Engl J Med 290 (1974): 344. [PMID: 4809290]
241	Tran PO, Gleason CE, Robertson RP "Inhibition of interleukin-1beta-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet beta-cell function." Diabetes 51 (2002): 1772-8. [PMID: 12031964]
242	Tremaine LM, Wilner KD, Preskorn SH "A study of the potential effect of sertraline on the pharmacokinetics and protein binding of tolbutamide." Clin Pharmacokinet 32(Suppl 1) (1997): 31-36. [PMID: 9068933]
243	Turtle JR, Burgess JA "Hypoglycemic action of fenfluramine in diabetes mellitus." Diabetes 22 (1973): 858-67. [PMID: 4749404]
244	Verdy M, Charbonneau L, Verdy I, Belanger R, Bolte E, Chiasson JL "Fenfluramine in the treatment of non-insulin-dependent diabetics: hypoglycemic versus anorectic effect." Int J Obes 7 (1983): 289-97. [PMID: 6629637]
245	Vuksan V, Sievenpiper JL, Koo VY, et al "American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus." Arch Intern Med 160 (2000): 1009-13. [PMID: 10761967]
246	Vuksan V, Stavro MP, Sievenpiper JL, et al "Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes." Diabetes Care 23 (2000): 1221-6. [PMID: 10977009]
247	Whitcroft IA, Thomas JM, Rawsthorne A, et al "Effects of alpha and beta adrenoceptor blocking drugs and ACE inhibitors on long term glucose and lipid control in hypertensive non-insulin dependent diabetics." Horm Metab Res Suppl 22 (1990): 42-6. [PMID: 1975246]
248	Wiederholt IC, Genco M, Foley JM "Recurrent episodes of hypoglycemia induced by propoxyphene." Neurology 17 (1967): 703-6. [PMID: 6067489]
249	Wing LM, Miners JO "Cotrimoxazole as an inhibitor of oxidative drug metabolism: effects of trimethoprim and sulphamethoxazole separately and combined on tolbutamide disposition." Br J Clin Pharmacol 20 (1985): 482-5. [PMID: 3878154]
250	World Health Organization "WHO Public Assessment Reports (WHOPARs).".
251	Wu B, Sato T, Kiyosue T, Arita M "Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs." Cardiovasc Res 26 (1992): 1095-101. [PMID: 1291087]
252	Golwyn DH, Sevlie CP "Monoamine oxidase inhibitor hypertensive crisis headache and orthostatic hypotension." J Clin Psychopharmacol 13 (1993): 77-8. [PMID: 8486823]
253	Product Information. Xatral (alfuzosin). Sanofi-Synthelabo Canada Inc, Markham, ON.
254	Reggev A, Vollhardt BR "Bradycardia induced by an interaction between phenelzine and beta blockers." Psychosomatics 30 (1992): 106-8. [PMID: 2913594]
255	Product Information. Tacaryl (methdilazine). Westwood Squibb Pharmaceutical Corporation, Buffalo, NY.
256	Adverse effects and complications of treatment with beta-adrenergic agonist drugs. Committee on drugs, the American Academy of Allergy and Immunology. J Allergy Clin Immunol 75 (1985): 443-9. [PMID: 2858503]
257	Finch JS "Cardiovascular toxicity: clinical evaluation of albuterol, isoproterenol and placebo in rising dose tolerance trial." Ann Allergy 47 (1981): 402-4. [PMID: 7030155]
258	Product Information. Alupent (metaproterenol). Boehringer-Ingelheim, Ridgefield, CT.
259	Product Information. Arcapta Neohaler (indacaterol). Novartis Pharmaceuticals, East Hanover, NJ.
260	Product Information. Breo Ellipta (fluticasone-vilanterol). GlaxoSmithKline, Research Triangle Park, NC.
261	Product Information. Brethaire (terbutaline). Novartis Pharmaceuticals, East Hanover, NJ.
262	Product Information. Brovana (arformoterol). Sepracor Inc, Marlborough, MA.
263	Product Information. Foradil (formoterol) Novartis Pharmaceuticals, East Hanover, NJ.
264	Product Information. Isuprel (isoproterenol). Sanofi Winthrop Pharmaceuticals, New York, NY.
265	Product Information. Maxair (pirbuterol). 3M Pharmaceuticals, St. Paul, MN.
266	Product Information. Proventil (albuterol). Schering Laboratories, Kenilworth, NJ.
267	Product Information. S2 Inhalant (racepinephrine). Nephron Pharmaceuticals, Orlando, FL.
268	Product Information. Severent (salmeterol). Glaxo Wellcome, Research Triangle Park, NC.
269	Product Information. Striverdi Respimat (olodaterol). Boehringer Ingelheim, Ridgefield, CT.
270	Product Information. Tornalate Metered Dose (bitolterol). Dura Pharmaceuticals, San Diego, CA.
271	Product Information. Xopenex (levalbuterol). Sepracor, Marlborough, MA.
272	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA.".
273	Cusson JR, Goldenberg E, Larochelle P "Effect of a novel monoamine-oxidase inhibitor, moclobemide on the sensitivity to intravenous tyramine and norepinephrine in humans." J Clin Pharmacol 31 (1991): 462-7. [PMID: 2050833]
274	Fenwick MJ, Muwanga CL "Anaphylaxis and monoamine oxidase inhibitors--the use of adrenaline." J Accid Emerg Med 17 (2000): 143-4. [PMID: 10718244]
275	Sjoerdsma A "Catecholamine-drug interactions in man." Pharmacol Rev 18 (1966): 673-83. [PMID: 5904180]
276	Thompson DS, Sweet RA, Marzula K, Peredes JC "Lack of interaction of monoamine oxidase inhibitors and epinephrine in an older patient." J Clin Psychopharmacol 17 (1997): 322-3. [PMID: 9241014]
277	Coleman AL, Robin AL, Pollack IP, Rudikoff MT, Enger C, Mayer PR "Cardiovascular and intraocular pressure effects and plasma concentrations of apraclonidine." Arch Ophthalmol 108 (1990): 1264-7. [PMID: 2205182]
278	Barsa JA, Saunders JC "A comparative study of tranylcypromine and paragyline." Psychopharmacologia 6 (1964): 295-8. [PMID: 5830807]
279	Jones EM, Dawson A "Neuroleptic malignant syndrome: a case report with post-mortem brain and muscle pathology." J Neurol Neurosurg Psychiatry 52 (1989): 1006-9. [PMID: 2795057]
280	Poster DS "Procarbazine-prochlorperazine interaction: an underreported phenomenon." J Med 9 (1978): 519-24. [PMID: 287765]
281	Product Information. Phenergan (promethazine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
282	Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7. [PMID: 3725002]
283	Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):.
284	Product Information. Rexulti (brexpiprazole). Otsuka American Pharmaceuticals Inc, Rockville, MD.
285	Product Information. Fycompa (perampanel). Eisai Inc, Teaneck, NJ.
286	Gulati OD, Dave BT, Gokhale SD, Shah KM "Antagonism of adrenergic neuron blockade in hypertensive subjects." Clin Pharmacol Ther 7 (1966): 510-4. [PMID: 5939974]
287	Iversen LL "Inhibition of noradrenaline uptake by drugs." J Pharm Pharmacol 17 (1965): 62-4. [PMID: 14285701]
288	Lee CH, Strosberg AM, Warren LA "The importance of catecholamine uptake in the reversal of guenethidine blockade of adrenergic neurons." Res Commun Chem Pathol Pharmacol 30 (1980): 3-14. [PMID: 7433767]
289	Ben Salem C, Fathallah N, Hmouda H, Bouraoui K "Drug-induced hypoglycaemia: an update." Drug Saf 34 (2011): 21-45. [PMID: 20942513]
290	Product Information. Afrezza (insulin inhalation, rapid acting). MannKind Corporation, Valencia, CA.
291	Product Information. Humalog (insulin lispro). Lilly, Eli and Company, Indianapolis, IN.
292	Product Information. Humulin 70/30 (insulin isophane-insulin regular). Lilly, Eli and Company, Indianapolis, IN.
293	Product Information. Ryzodeg 70/30 FlexTouch (insulin aspart-insulin degludec). Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.
294	Product Information. Tresiba FlexTouch (insulin degludec). Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.
295	Vuorinen-Markkola H, Yki-Jarvinen H "Antihypertensive therapy with enalapril improves glucose storage and insulin sensitivity in hypertensive patients with non-insulin-dependent diabetes mellitus." Metabolism 44 (1995): 85-9. [PMID: 7854171]
296	Product Information. Ketalar (ketamine). JHP Pharmaceuticals, Saddle River, NJ.
297	Filibeck DJ, Grimm D, Forman WB, Leidner BA "Metoclopramide-induced hypertensive crisis." Clin Pharm 3 (1984): 548-9. [PMID: 6541544]
298	Product Information. Reglan (metoclopramide). Wyeth-Ayerst Laboratories, Philadelphia, PA.
299	Product Information. Mektovi (binimetinib). Array BioPharma Inc., Boulder, CO.
300	Product Information. Zulresso (brexanolone). Sage Therapeutics, Inc., Cambridge, MA.
301	Product Information. Nurtec ODT (rimegepant). Biohaven Pharmaceuticals, New Haven, CT.
302	Product Information. Talzenna (talazoparib). Pfizer U.S. Pharmaceuticals Group, New York, NY.
303	Product Information. Ubrelvy (ubrogepant). Allergan Inc, Irvine, CA.

Details of Drug

Details of Drug

Cite MecDDI

About MecDDI

Correspondence