Details of Drug

Details of Drug

 Drug General Information (ID: D0998)
  Drug Name
Memantine
  Drug Type Small molecule
  Drug Synonymous
Memantine ER; Namenda XR; Memantine (extended release); Memantine (extended release), Forest
    Click to Show/Hide
  Disease Class 8A20: Alzheimer disease
  Therapeutic Class Cholinesterase Inhibitors
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C12H21N
  InChI 1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3
  InChIKey BUGYDGFZZOZRHP-UHFFFAOYSA-N
  Canonical SMILES CC12CC3CC(C1)(CC(C3)(C2)N)C
  External Link
Pubchem ID 4054
CAS Number 19982-08-2
CHEBI ID 64312
TTD ID D01JEU
INTEDE ID DR2292
VARIDT ID DR00023

Drug-Drug Interaction Network
  Sunburst Graph
AM002  Affected cellular transport
AM005  Affected excretion pathways
AM006  Pharmacodynamic additive effects
BM010  Transporter inhibition
BM028  Competitive inhibition of renal tubular secretion
BM029  Altered urine pH
BM033  Additive anticholinergic effects
BM040  Additive dopaminergic effects
  Relation Graph
 Full list of drugs interacting with Memantine
      Affected cellular transport
   Transporter inhibition Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1645
 
Trimethoprim
 
C14H18N4O3
 
5578 
Moderate    Inter Info   
[16], [19], [20]
      Affected excretion pathways
   Competitive inhibition of renal tubular secretion Drug Num:  15
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0022
 
Acyclovir
 
C8H11N5O3
 
135398513 
Minor    Inter Info   
[22], [23], [21]
D0335
 
Cidofovir
 
C8H14N3O6P
 
60613 
Minor    Inter Info   
[22], [23], [21]
D0337
 
Cimetidine
 
C10H16N6S
 
2756 
Minor    Inter Info   
[22], [23], [21]
D0710
 
Ganciclovir
 
C9H13N5O4
 
135398740 
Minor    Inter Info   
[22], [23], [21]
D0771
 
Hydrochlorothiazide
 
C7H8ClN3O4S2
 
3639 
Minor    Inter Info   
[22], [23], [21]
D0664
 
Flecainide
 
C17H20F6N2O3
 
3356 
Minor    Inter Info   
[22], [23], [21]
D1676
 
Valganciclovir
 
C14H22N6O5
 
135413535 
Minor    Inter Info   
[22], [23], [21]
D1015
 
Metformin
 
C4H11N5
 
4091 
Minor    Inter Info   
[22], [23], [21]
D1061
 
Midodrine
 
C12H18N2O4
 
4195 
Minor    Inter Info   
[22], [23], [21]
D1133
 
Nicotine
 
C10H14N2
 
89594 
Minor    Inter Info   
[22], [23], [21]
D1343
 
Procainamide
 
C13H21N3O
 
4913 
Minor    Inter Info   
[22], [23], [21]
D1371
 
Quinidine
 
C20H24N2O2
 
441074 
Minor    Inter Info   
[22], [23], [21]
D1381
 
Ranitidine
 
C13H22N4O3S
 
3001055 
Minor    Inter Info   
[22], [23], [21]
D1631
 
Triamterene
 
C12H11N7
 
5546 
Minor    Inter Info   
[22], [23], [21]
D1672
 
Valaciclovir
 
C13H20N6O4
 
135398742 
Minor    Inter Info   
[22], [23], [21]
   Altered urine pH Drug Num:  9
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0012
 
Acetazolamide
 
C4H6N4O3S2
 
1986 
Minor    Inter Info   
[21]
D0479
 
Diclofenamide
 
C6H6Cl2N2O4S2
 
3038 
Minor    Inter Info   
[21]
D0886
 
Lactic acid
 
C3H6O3
 
612 
Minor    Inter Info   
[21]
D1319
 
Potassium citrate
 
C6H5K3O7
 
13344 
Minor    Inter Info   
[21]
D1478
 
Sodium acetate
 
C2H3NaO2
 
517045 
Minor    Inter Info   
[21]
D1480
 
Sodium bicarbonate
 
CHNaO3
 
516892 
Minor    Inter Info   
[21]
D1483
 
Sodium citrate
 
C6H5Na3O7
 
6224 
Minor    Inter Info   
[21]
D1654
 
Tromethamine
 
C4H11NO3
 
6503 
Minor    Inter Info   
[21]
D1018
 
Methazolamide
 
C5H8N4O3S2
 
4100 
Minor    Inter Info   
[21]
      Pharmacodynamic additive effects
   Additive anticholinergic effects Drug Num:  87
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0068
 
Amitriptyline
 
C20H23N
 
2160 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0072
 
Amoxapine
 
C17H16ClN3O
 
2170 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0123
 
Atropine
 
C17H23NO3
 
174174 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0135
 
Azatadine
 
C20H22N2
 
19861 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0160
 
Benzatropine
 
C21H25NO
 
1201549 
Moderate    Inter Info   
[6], [8], [14]
D0183
 
Biperiden
 
C21H29NO
 
2381 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0214
 
Brompheniramine
 
C16H19BrN2
 
6834 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0259
 
Carbinoxamine
 
C16H19ClN2O
 
2564 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0351
 
Clemastine
 
C21H26ClNO
 
26987 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0353
 
Clidinium
 
C22H26NO3+
 
2784 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0370
 
Clozapine
 
C18H19ClN4
 
135398737 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0398
 
Cyclobenzaprine
 
C20H21N
 
2895 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0403
 
Cyproheptadine
 
C21H21N
 
2913 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0424
 
Darifenacin
 
C28H30N2O2
 
444031 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0456
 
Dexbrompheniramine
 
C16H19BrN2
 
16960 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0482
 
Dicyclomine
 
C19H35NO2
 
3042 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0498
 
Dimenhydrinate
 
C24H28ClN5O3
 
10660 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0508
 
Disopyramide
 
C21H29N3O
 
3114 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0532
 
Doxylamine
 
C17H22N2O
 
3162 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0733
 
Glycopyrronium
 
C19H28NO3+
 
3494 
Moderate    Inter Info   
[6], [8], [14]
D0750
 
Haloperidol
 
C21H23ClFNO2
 
3559 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0781
 
Hydroxyzine
 
C21H27ClN2O2
 
3658 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0782
 
Hyoscyamine
 
C17H23NO3
 
154417 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0795
 
Imipramine
 
C19H24N2
 
3696 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0957
 
Loxapine
 
C18H18ClN3O
 
3964 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0979
 
Maprotiline
 
C20H23N
 
4011 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0987
 
Meclizine
 
C25H27ClN2
 
4034 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0020
 
Acrivastine
 
C22H24N2O2
 
5284514 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0037
 
Alimemazine
 
C18H22N2S
 
5574 
Moderate    Inter Info   
[6], [8], [14]
D0105
 
Aripiprazole
 
C23H27Cl2N3O2
 
60795 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0112
 
Asenapine
 
C17H16ClNO
 
3036780 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0154
 
Belladonna
 
C34H42N2O4
 
265028 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0202
 
Brexpiprazole
 
C25H27N3O2S
 
11978813 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0262
 
Cariprazine
 
C21H32Cl2N4O
 
11154555 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0323
 
Chlorpheniramine
 
C16H19ClN2
 
2725 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0361
 
Clomipramine
 
C19H23ClN2
 
2801 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0397
 
Cyclizine
 
C18H22N2
 
6726 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0446
 
Desipramine
 
C18H22N2
 
2995 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0502
 
Diphenhydramine
 
C17H21NO
 
3100 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0525
 
Doxepin
 
C19H21NO
 
667477 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0526
 
Doxepin (topical)
 
C19H21NO
 
667477 
Moderate    Inter Info   
[6], [8], [14]
D0655
 
Fesoterodine
 
C26H37NO3
 
6918558 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0662
 
Flavoxate
 
C24H25NO4
 
3354 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0791
 
Iloperidone
 
C24H27FN2O4
 
71360 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0959
 
Lumateperone
 
C24H28FN3O
 
21302490 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0961
 
Lurasidone
 
C28H36N4O2S
 
213046 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1000
 
Mepenzolate
 
C21H26NO3+
 
4057 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1006
 
Mepyramine
 
C17H23N3O
 
4992 
Moderate    Inter Info   
[6], [8], [14]
D1026
 
Methotrimeprazine
 
C19H24N2OS
 
72287 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1031
 
Methscopolamine
 
C18H24NO4+
 
71183 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1084
 
Molindone
 
C16H24N2O2
 
23897 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1188
 
Orphenadrine
 
C18H23NO
 
4601 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1202
 
Oxybutynin
 
C22H31NO3
 
4634 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1215
 
Paliperidone
 
C23H27FN4O3
 
115237 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1264
 
Phenindamine
 
C19H19N
 
11291 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1282
 
Phenyltoloxamine
 
C17H21NO
 
7077 
Moderate    Inter Info   
[6], [8], [14]
D1292
 
Pimozide
 
C28H29F2N3O
 
16362 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1368
 
Quetiapine
 
C21H25N3O2S
 
5002 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1491
 
Solifenacin
 
C23H26N2O2
 
154059 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1576
 
Thiothixene
 
C23H29N3O2S2
 
941651 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1010
 
Mesoridazine
 
C21H26N2OS2
 
4078 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1019
 
Methdilazine
 
C18H20N2S
 
14677 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1158
 
Nortriptyline
 
C19H21N
 
4543 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1166
 
Olanzapine
 
C17H20N4S
 
135398745 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1346
 
Prochlorperazine
 
C20H24ClN3S
 
4917 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1347
 
Procyclidine
 
C19H29NO
 
4919 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1351
 
Promazine
 
C17H20N2S
 
4926 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1354
 
Propantheline
 
C23H30NO3+
 
4934 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1355
 
Propiomazine
 
C20H24N2OS
 
4940 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1361
 
Protriptyline
 
C19H21N
 
4976 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1413
 
Risperidone
 
C23H27FN4O2
 
5073 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1450
 
Scopolamine
 
C17H21NO4
 
3000322 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1572
 
Thiethylperazine
 
C22H29N3S2
 
5440 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1607
 
Tolterodine
 
C22H31NO
 
443879 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1637
 
Trifluoperazine
 
C21H24F3N3S
 
5566 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1638
 
Triflupromazine
 
C18H19F3N2S
 
5568 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1641
 
Trihexyphenidyl
 
C20H31NO
 
5572 
Moderate    Inter Info   
[16], [17], [18]
D1647
 
Trimipramine
 
C20H26N2
 
5584 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1649
 
Tripelennamine
 
C16H21N3
 
5587 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1650
 
Triprolidine
 
C19H22N2
 
5282443 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1656
 
Trospium
 
C25H30NO3+
 
5284632 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D1726
 
Ziprasidone
 
C21H21ClN4OS
 
60854 
Moderate    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
   Additive dopaminergic effects Drug Num:  11
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0097
 
Apomorphine
 
C17H17NO2
 
6005 
Minor    Inter Info   
[19], [17]
D0228
 
Cabergoline
 
C26H37N5O2
 
54746 
Minor    Inter Info   
[19], [17]
D0575
 
Entacapone
 
C14H15N3O5
 
5281081 
Minor    Inter Info   
[19], [17]
D0212
 
Bromocriptine
 
C32H40BrN5O5
 
31101 
Minor    Inter Info   
[19], [17]
D0918
 
Levodopa
 
C9H11NO4
 
6047 
Minor    Inter Info   
[19], [17]
D1182
 
Opicapone
 
C15H10Cl2N4O6
 
135565903 
Minor    Inter Info   
[19], [17]
D1255
 
Pergolide
 
C19H26N2S
 
47811 
Minor    Inter Info   
[19], [17]
D1431
 
Rotigotine
 
C19H25NOS
 
59227 
Minor    Inter Info   
[19], [17]
D1325
 
Pramipexole
 
C10H17N3S
 
119570 
Minor    Inter Info   
[19], [17]
D1427
 
Ropinirole
 
C16H24N2O
 
5095 
Minor    Inter Info   
[19], [17]
D1604
 
Tolcapone
 
C14H11NO5
 
4659569 
Minor    Inter Info   
[19], [17]
References
1 Cohen MA, Alfonso CA, Mosquera M. Development of urinary retention during treatment with clozapine and meclizine [published correction appears in Am J Psychiatry 1994 Jun;151(6):952]. Am J Psychiatry. 1994;151(4):619-620. [PMID: 8147469]
2 Forester D "Fatal drug-induced heat stroke." JACEP 7 (1978): 243-4. [PMID: 661049]
3 Gershon S, Neubauer H, Sundland DM "Interaction between some anticholinergic agents and phenothiazines." Clin Pharmacol Ther 6 (1965): 749-56. [PMID: 4378954]
4 Hvizdos AJ, Bennett JA, Wells BG, Rappaport KB, Mendel SA "Anticholinergic psychosis in a patient receiving usual doses of haloperidol." Clin Pharm 2 (1983): 174-8. [PMID: 6883947]
5 Johnson AL, Hollister LE, Berger PA "The anticholinergic intoxication syndrome: diagnosis and treatment." J Clin Psychiatry 42 (1981): 313-7. [PMID: 7251568]
6 Kulik AV, Wilbur R "Delirium and stereotypy from anticholinergic antiparkinson drugs." Prog Neuropsychopharmacol Biol Psychiatry 6 (1982): 75-82. [PMID: 7202232]
7 Lee BS "Possibility of hyperpyrexia with antipsychotic and anticholinergic drugs." J Clin Psychiatry 47 (1986): 571. [PMID: 3771507]
8 Mann SC, Boger WP "Psychotropic drugs, summer heat and humidity, and hyperplexia: a danger restated." Am J Psychiatry 135 (1978): 1097-100. [PMID: 29501]
9 Moreau A, Jones BD, Banno V "Chronic central anticholinergic toxicity in manic depressive illness mimicking dementia." Can J Psychiatry 31 (1986): 339-41. [PMID: 3708528]
10 Product Information. Artane (trihexyphenidyl). Lederle Laboratories, Wayne, NJ.
11 Product Information. Cogentin (benztropine). Merck & Co, Inc, West Point, PA.
12 Sarnquist F, Larson CP Jr "Drug-induced heat stroke." Anesthesiology 39 (1973): 348-50. [PMID: 4728582]
13 Stadnyk AN, Glezos JD "Drug-induced heat stroke." Can Med Assoc J 128 (1983): 957-9. [PMID: 6831343]
14 Warnes H, Lehmann HE, Ban TA "Adynamic ileus during psychoactive medication: a report of three fatal and five severe cases." Can Med Assoc J 96 (1967): 1112-3. [PMID: 6021058]
15 Zelman S, Guillan R "Heat stroke in phenothiazine-treated patients: a report of three fatalities." Am J Psychiatry 126 (1970): 1787-90. [PMID: 5441734]
16 Cerner Multum, Inc. "Australian Product Information.".
17 Multum Information Services, Inc. Expert Review Panel.
18 Product Information. Reminyl (galantamine) Janssen Pharmaceuticals, Titusville, NJ.
19 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
20 Product Information. Bactrim (trimethoprim-sulfamethoxazole). Roche Laboratories, Nutley, NJ.
21 Product Information. Namenda (memantine). Forest Pharmaceuticals, St. Louis, MO.
22 Ace LN, Jaffe JM, Kunka RL "Effect of food and an antacid on quinidine bioavailability." Biopharm Drug Dispos 4 (1983): 183-90. [PMID: 6882885]
23 Min DI, Ku YM, Geraets DR, Lee HC "Effect of grapefruit juice on the pharmacokinetics and pharmacodynamics of quinidine in healthy volunteers." J Clin Pharmacol 36 (1996): 469-76. [PMID: 8739026]