Details of Drug

Drug General Information (ID: D0973)
Drug Name	Magnesium hydroxide
Drug Type	Small molecule
Drug Synonymous	Magnesium dihydroxide; Nemalite; magnesium;dihydroxide; 1317-43-7; Milmag; Magnesiamaito; Reachim; Versamag; Duhor; Brucite (Mg(OH)2); Magmesia hydrate; Kyowamag F; Hydrofy N; Marinco H; Duhor N; Hydro-mag MA; Ebson RF; FloMag H; MagneClear 58; Di-Gel; FloMag HUS; Kisuma 5; Kisuma 5A; Kisuma 5B; Kisuma 5E; Combustrol 500; Haley's MO; Kisuma 4AF; Kisuma 5BG; Mint-O-Mag; Baschem 12; Magnifin H 10; Kisuma 5B-N; Kisuma 78; Kisuma S 4; Alcanex NHC 25; Hydrofy G 1.0; Hydrofy G 1.5; Hydrofy G 2.5; Magnesium Hydroxide Nanoparticles / Nanopowder; Lycal 96 HSE; Mag Chem MH 10; Magnesium hydroxide gel; Marinco H 1241; Martinal VPF 8812; H2MgO2; Phillips magnesia tablets; Star 200; Asahi Glass 200-06; Magnesium oxide (Mg(OH)2); CCRIS 3342; CCRIS 6159; HSDB 659; KX 8S(A); KX 8S(B); Ki 22-5B; Phillips milk of magnesia liquid; DSB 100; EINECS 215-170-3; EINECS 215-274-9; DP 393; Milmag (TN); S/G 84; Mint-o-mag (TN); Magnesium Hydroxide, powder; 200-06H; Magnesium Hydroxide Nanopowder; Magnesia, (Milk of) (USP); C16H17KN2O4S; Magnesium hydroxide (JAN/USP); Magnesium hydroxide [USP:JAN]; CS-B1709; Magnesium hydroxide, BioXtra, >=95%; Magnesium hydroxide, reagent grade, 95%; Magnesium hydroxide, 95.00-100.50%; Magnesium hydroxide, Vetec(TM) reagent grade; D00731; EC 215-170-3; Magnesium hydroxide, BioUltra, >=99.0% (KT); Magnesium hydroxide, SAJ first grade, >=95.0%; Magnesium hydroxide, United States Pharmacopeia (USP) Reference Standard; Magnesium hydroxide, nanopowder, <100 nm particle size (laser PSA), 99.8% trace metals basis Click to Show/Hide
Therapeutic Class	Antacids/Laxatives
Structure
Structure	3D Structure		2D Structure
Formula	H2MgO2
InChI	InChI=1S/Mg.2H2O/h;2*1H2/q+2;;/p-2
InChIKey	VTHJTEIRLNZDEV-UHFFFAOYSA-L
Canonical SMILES	[OH-].[OH-].[Mg+2]
External Link
External Link	Pubchem ID	14791

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM003 Affected organization distribution AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM001 Altered gastrointestinal dynamics BM003 Complex formation BM004 Adsorption BM005 Altered gastric pH BM009 Altered absorption (Unspecific) BM014 Interference of cell/tissue uptake BM029 Altered urine pH BM059 Increased risk of hypermagnesemia BM065 Increased risk of hypokalemia BM081 Increased risk of ventricular arrhythmias BM107 Attenuated pharmacological effects (Unspecific) BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Magnesium hydroxide
Affected gastrointestinal absorption
	Altered gastrointestinal dynamics					Drug Num: 15
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0045		Alprazolam	C17H13ClN4	2118	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0317		Chlordiazepoxide	C16H14ClN3O	2712	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0356		Clobazam	C16H13ClN2O2	2789	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0362		Clonazepam	C15H10ClN3O3	2802	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0365		Clorazepic acid	C16H11ClN2O3	2809	Minor		Inter Info	[185], [186], [189]
D0473		Diazepam	C16H13ClN2O	3016	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0604		Estazolam	C16H11ClN4	3261	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0679		Flurazepam	C21H23ClFN3O	3393	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0748		Halazepam	C17H12ClF3N2O	31640	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D0951		Lorazepam	C15H10Cl2N2O2	3958	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D1060		Midazolam	C18H13ClFN3	4192	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D1197		Oxazepam	C15H11ClN2O2	4616	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D1367		Quazepam	C17H11ClF4N2S	4999	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D1547		Temazepam	C16H13ClN2O2	5391	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
D1632		Triazolam	C17H12Cl2N4	5556	Minor		Inter Info	[184], [185], [186], [187], [188], [189], [190], [191], [192]
	Complex formation					Drug Num: 65
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0515		Dolutegravir	C20H19F2N3O5	54726191	Major		Inter Info	[1]
D0181		Bictegravir	C21H18F3N3O5	90311989	Major		Inter Info	[2], [3], [4]
D1231		Patiromer	NA	NA	Major		Inter Info	[6], [7], [8]
D1377		Raltegravir	C20H21FN6O5	54671008	Major		Inter Info	[10], [2], [3], [11], [12], [13], [14]
D1605		Tolevamer	C11H16O3S	58817179	Major		Inter Info	[6], [7], [8]
D0034		Alendronic acid	C4H13NO7P2	2088	Moderate		Inter Info	[30], [31], [32]
D0139		Azithromycin	C38H72N2O12	447043	Moderate		Inter Info	[39]
D0271		Cefaclor	C15H14ClN3O4S	51039	Moderate		Inter Info	[47]
D0277		Cefdinir	C14H13N5O5S2	6915944	Moderate		Inter Info	[48]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[2], [3], [52], [53], [54], [55], [56], [57]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0433		Deferiprone	C7H9NO2	2972	Moderate		Inter Info	[99]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[27], [52], [101], [102], [103], [104], [105], [106], [107], [108], [82], [109], [92]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[27], [52], [101], [102], [103], [104], [105], [106], [107], [108], [82], [109], [92]
D0561		Eltrombopag	C25H22N4O4	135449332	Moderate		Inter Info	[3], [110]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0623		Etidronic acid	C2H8O7P2	3305	Moderate		Inter Info	[31], [113], [32]
D0656		Fexofenadine	C32H39NO4	3348	Moderate		Inter Info	[114]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[2], [3], [52], [53], [54], [55], [56], [57]
D0783		Ibandronate	C9H23NO7P2	60852	Moderate		Inter Info	[115], [116], [30], [31], [117], [32]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[129], [10], [2], [3], [130], [131], [132], [133], [134], [135], [136]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[129], [10], [2], [3], [130], [131], [132], [133], [134], [135], [136]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Moderate		Inter Info	[129], [10], [2], [3], [130], [131], [132], [133], [134], [135], [136]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0144		Baloxavir marboxil	C27H23F2N3O7S	124081896	Moderate		Inter Info	[138]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D1175		Omadacycline	C29H40N4O7	54697325	Moderate		Inter Info	[27], [52], [101], [102], [103], [104], [105], [106], [107], [108], [82], [109], [92]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[27], [52], [101], [102], [103], [104], [105], [106], [107], [108], [82], [109], [92]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[27], [52], [101], [102], [103], [104], [105], [106], [107], [108], [82], [109], [92]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[156]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D1209		Oxytetracycline	C22H24N2O9	54675779	Moderate		Inter Info	[27], [52], [101], [102], [103], [104], [105], [106], [107], [108], [82], [109], [92]
D1245		Penicillamine	C5H11NO2S	5852	Moderate		Inter Info	[162], [163], [164], [165], [166], [167], [168], [82]
D1412		Risedronic acid	C7H11NO7P2	5245	Moderate		Inter Info	[30], [31], [32]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[27], [52], [101], [102], [103], [104], [105], [106], [107], [108], [82], [109], [92]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[132], [133], [134]
D1584		Tiludronic acid	C7H9ClO6P2S	60937	Moderate		Inter Info	[31], [113], [32]
D1635		Triethylenetetramine	C6H18N4	5565	Moderate		Inter Info	[177]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[62], [63], [64], [65], [66], [67], [40], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92]
D0010		Acebutolol	C18H28N2O4	1978	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D0117		Atenolol	C14H22N2O3	2249	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D0173		Betaxolol	C18H29NO3	2369	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D0188		Bisoprolol	C18H31NO4	2405	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D0265		Carteolol	C16H24N2O3	2583	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D0267		Carvedilol	C24H26N2O4	2585	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D0490		Digitoxin	C41H64O13	441207	Minor		Inter Info	[206], [207], [208], [52], [209], [210], [82], [211], [212]
D0491		Digoxin	C41H64O14	2724385	Minor		Inter Info	[206], [207], [208], [52], [209], [210], [82], [211], [212]
D0705		Gabapentin	C9H17NO2	3446	Minor		Inter Info	[214]
D0884		Labetalol	C19H24N2O3	3869	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D1049		Metoprolol	C15H25NO3	4171	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D1098		Nadolol	C17H27NO4	39147	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D1114		Nebivolol	C22H25F2NO4	71301	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Minor		Inter Info	[224]
D1244		Penbutolol	C18H29NO2	37464	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D1293		Pindolol	C14H20N2O2	4828	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D1357		Propranolol	C16H21NO2	4946	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
D1585		Timolol	C13H24N4O3S	33624	Minor		Inter Info	[52], [178], [179], [180], [181], [182], [183]
	Adsorption					Drug Num: 8
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0123		Atropine	C17H23NO3	174174	Moderate		Inter Info	[3]
D1350		Proguanil	C11H16ClN5	6178111	Moderate		Inter Info	[3], [141]
D1366		Pyrimethamine	C12H13ClN4	4993	Moderate		Inter Info	[3], [141]
D0037		Alimemazine	C18H22N2S	5574	Minor		Inter Info	[27], [58], [61]
D1019		Methdilazine	C18H20N2S	14677	Minor		Inter Info	[27], [58], [59], [60], [61]
D1352		Promethazine	C17H20N2S	4927	Minor		Inter Info	[27], [58], [59], [60], [61]
D1355		Propiomazine	C20H24N2OS	4940	Minor		Inter Info	[27], [58], [59], [60], [61]
D1572		Thiethylperazine	C22H29N3S2	5440	Minor		Inter Info	[27], [58], [59], [60], [61]
	Altered gastric pH					Drug Num: 64
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1459		Selpercatinib	C29H31N7O3	134436906	Major		Inter Info	[9]
D0013		Acetohexamide	C15H20N2O4S	1989	Moderate		Inter Info	[20], [21], [22], [23], [24], [25], [26]
D0074		Amphetamine	C9H13N	3007	Moderate		Inter Info	[33]
D0080		Amprenavir	C25H35N3O6S	65016	Moderate		Inter Info	[34], [35]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[36], [37], [38]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[40], [41]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[33]
D0184		Bisacodyl	C22H19NO4	2391	Moderate		Inter Info	[3]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[3], [42]
D0278		Cefditoren	C19H18N6O5S3	9870843	Moderate		Inter Info	[49]
D0288		Cefpodoxime	C15H17N5O6S2	6335986	Moderate		Inter Info	[40], [50], [51], [41]
D0297		Cefuroxime	C16H16N4O8S	5479529	Moderate		Inter Info	[40], [50], [51], [41]
D0325		Chlorpropamide	C10H13ClN2O3S	2727	Moderate		Inter Info	[20], [21], [22], [23], [24], [25], [26]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[2], [3], [93], [94], [95], [96], [97]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[98]
D0465		Dextroamphetamine	C9H13N	5826	Moderate		Inter Info	[33]
D0595		Erlotinib	C22H23N3O4	176870	Moderate		Inter Info	[2], [3], [111], [112]
D0727		Glimepiride	C24H34N4O5S	3476	Moderate		Inter Info	[20], [21], [22], [23], [24], [25], [26]
D0728		Glipizide	C21H27N5O4S	3478	Moderate		Inter Info	[20], [21], [22], [23], [24], [25], [26]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[20], [21], [22], [23], [24], [25], [26]
D0867		Itraconazole	C35H38Cl2N8O4	55283	Moderate		Inter Info	[119], [120], [121], [122], [123]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Moderate		Inter Info	[119], [120], [124], [125], [3], [126], [127], [123]
D0898		Ledipasvir	C49H54F2N8O6	67505836	Moderate		Inter Info	[128]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[33]
D0008		Acalabrutinib	C26H23N7O2	71226662	Moderate		Inter Info	[137]
D0229		Cabotegravir	C19H17F2N3O5	54713659	Moderate		Inter Info	[2], [125], [139], [140]
D1124		Neratinib	C30H29ClN6O3	9915743	Moderate		Inter Info	[143]
D1686		Velpatasvir	C49H54N8O8	67683363	Moderate		Inter Info	[144]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[145], [33], [146]
D1094		Mycophenolate mofetil	C23H31NO7	5281078	Moderate		Inter Info	[152], [153], [154], [155]
D1095		Mycophenolic acid	C17H20O6	446541	Moderate		Inter Info	[152], [153], [154], [155]
D1136		Nilotinib	C28H22F3N7O	644241	Moderate		Inter Info	[2], [3]
D1218		Pancrelipase	C8H8Na2O5	8519	Moderate		Inter Info	[2], [3], [141]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[3], [157], [158], [159], [160], [161]
D1400		Rifampicin	C43H58N4O12	135398735	Moderate		Inter Info	[172]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[173]
D1408		Riociguat	C20H19FN8O2	11304743	Moderate		Inter Info	[174]
D1430		Rosuvastatin	C22H28FN3O6S	446157	Moderate		Inter Info	[175]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Moderate		Inter Info	[176], [38]
D1601		Tolazamide	C14H21N3O3S	5503	Moderate		Inter Info	[20], [21], [22], [23], [24], [25], [26]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[20], [21], [22], [23], [24], [25], [26]
D0133		Axitinib	C22H18N4OS	6450551	Minor		Inter Info	[193]
D0156		Benazepril	C24H28N2O5	5362124	Minor		Inter Info	[194]
D0254		Captopril	C9H15NO3S	44093	Minor		Inter Info	[194]
D0337		Cimetidine	C10H16N6S	2756	Minor		Inter Info	[195], [196], [197], [198], [199], [27], [200], [201], [202], [203], [204], [205]
D0539		Duloxetine	C18H19NOS	60835	Minor		Inter Info	[213]
D0567		Enalapril	C20H28N2O5	5388962	Minor		Inter Info	[194]
D0636		Famotidine	C8H15N7O2S3	5702160	Minor		Inter Info	[195], [196], [197], [198], [199], [27], [200], [201], [202], [203], [204], [205]
D0695		Fosinopril	C30H46NO7P	55891	Minor		Inter Info	[194]
D0918		Levodopa	C9H11NO4	6047	Minor		Inter Info	[215], [216], [217], [218]
D0938		Lisinopril	C21H31N3O5	5362119	Minor		Inter Info	[194]
D0991		Mefenamic acid	C15H15NO2	4044	Minor		Inter Info	[221]
D1082		Moexipril	C27H34N2O7	91270	Minor		Inter Info	[194]
D1109		Naproxen	C14H14O3	156391	Minor		Inter Info	[222], [223]
D1151		Nizatidine	C12H21N5O2S2	3033637	Minor		Inter Info	[195], [196], [197], [198], [199], [27], [200], [201], [202], [203], [204], [205]
D1256		Perindopril	C19H32N2O5	107807	Minor		Inter Info	[194]
D1313		Ponatinib	C29H27F3N6O	24826799	Minor		Inter Info	[2], [225]
D1369		Quinapril	C25H30N2O5	54892	Minor		Inter Info	[194]
D1379		Ramipril	C23H32N2O5	5362129	Minor		Inter Info	[194]
D1381		Ranitidine	C13H22N4O3S	3001055	Minor		Inter Info	[195], [196], [197], [198], [199], [27], [200], [201], [202], [203], [204], [205]
D1382		Ranitidine (bismuth citrate)	C13H22N4O3S	3001055	Minor		Inter Info	[195], [198], [27]
D1581		Ticlopidine	C14H14ClNS	5472	Minor		Inter Info	[226]
D1618		Trandolapril	C24H34N2O5	5484727	Minor		Inter Info	[194]
D1701		Vismodegib	C19H14Cl2N2O3S	24776445	Minor		Inter Info	[2], [3], [227]
	Altered absorption (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0439		Delavirdine	C22H28N6O3S	5625	Moderate		Inter Info	[100]
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0670		Fludeoxyglucose (18F)	C6H11FO5	170049	Moderate		Inter Info	[2], [141], [142]
Affected excretion pathways
	Altered urine pH					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[27], [28], [29]
D0331		Choline salicylate	C12H19NO4	54686350	Moderate		Inter Info	[27], [28], [29]
D1020		Methenamine	C6H12N4	4101	Moderate		Inter Info	[147], [148], [149], [150], [151]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[169], [170], [171]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[27], [28], [29]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[27], [28], [29]
Pharmacodynamic additive effects
	Increased risk of hypermagnesemia					Drug Num: 12
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0233		Calcifediol	C27H44O2	5283731	Moderate		Inter Info	[43], [44], [45], [46]
D0234		Calcitriol	C27H44O3	5280453	Moderate		Inter Info	[43], [44], [45], [46]
D0328		Cholecalciferol	C27H44O	5280795	Moderate		Inter Info	[43], [44], [45], [46]
D0495		Dihydrotachysterol	C28H46O	5311071	Moderate		Inter Info	[43], [44], [45], [46]
D0527		Doxercalciferol	C28H44O2	5281107	Moderate		Inter Info	[43], [44], [45], [46]
D0591		Ergocalciferol	C28H44O	5280793	Moderate		Inter Info	[43], [44], [45], [46]
D0968		Magnesium carbonate	CMgO3	11029	Moderate		Inter Info	[3]
D0969		Magnesium chloride	Cl2H12MgO6	643991	Moderate		Inter Info	[3]
D0972		Magnesium glycinate	C4H8MgN2O4	84645	Moderate		Inter Info	[3]
D0974		Magnesium oxide	MgO	14792	Moderate		Inter Info	[3]
D0975		Magnesium sulfate	MgO4S	24083	Moderate		Inter Info	[3]
D1226		Paricalcitol	C27H44O3	5281104	Moderate		Inter Info	[43], [44], [45], [46]
	Increased risk of hypokalemia					Drug Num: 12
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[15], [16], [18]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[15], [16], [18]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[15], [16], [18]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[15], [16], [18]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[15], [16], [18]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[15], [16], [18]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[15], [16], [18]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[15], [16], [18]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[15], [16], [18]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[15], [16], [18]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[15], [16], [18]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[15], [16], [18]
	Increased risk of ventricular arrhythmias					Drug Num: 133
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0003		Abarelix	C72H95ClN14O14	16131215	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0007		Abiraterone	C24H31NO	132971	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0067		Amisulpride	C17H27N3O4S	2159	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0084		Anagrelide	C10H7Cl2N3O	135409400	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0097		Apomorphine	C17H17NO2	6005	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0107		Arsenic trioxide	As2O3	14888	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0115		Astemizole	C28H31FN4O	2247	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0170		Bepridil	C24H34N2O	2351	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0180		Bicalutamide	C18H14F4N2O4S	2375	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0230		Cabozantinib	C28H24FN3O5	25102847	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D0336		Cilostazol	C20H27N5O2	2754	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0342		Cisapride	C23H29ClFN3O4	6917698	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0345		Citalopram	C20H21FN2O	2771	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0349		Clarithromycin	C38H69NO13	84029	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0358		Clofazimine	C27H22Cl2N4	2794	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0370		Clozapine	C18H19ClN4	135398737	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0437		Degarelix	C82H103ClN18O16	16136245	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0467		Dextropropoxyphene	C22H29NO2	10100	Moderate		Inter Info	[2], [3], [17]
D0508		Disopyramide	C21H29N3O	3114	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0513		Dofetilide	C19H27N3O5S2	71329	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0514		Dolasetron	C19H20N2O3	3033818	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0534		Dronedarone	C31H44N2O5S	208898	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0535		Droperidol	C22H22FN3O2	3168	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0554		Efavirenz	C14H9ClF3NO2	64139	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0599		Escitalopram	C20H21FN2O	146570	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0632		Ezogabine	C16H18FN3O2	121892	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0664		Flecainide	C17H20F6N2O3	3356	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0667		Fluconazole	C13H12F2N6O	3365	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0676		Fluoxetine	C17H18F3NO	3386	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D0682		Flutamide	C11H11F3N2O3	3397	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0694		Foscarnet	CH3O5P	3415	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0737		Goserelin	C59H84N18O14	5311128	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0750		Haloperidol	C21H23ClFNO2	3559	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0758		Histrelin	C66H86N18O12	25077993	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0781		Hydroxyzine	C21H27ClN2O2	3658	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0787		Ibutilide	C20H36N2O3S	60753	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0791		Iloperidone	C24H27FN2O4	71360	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0806		Inotuzumab ozogamicin	NA	NA	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0903		Lenvatinib	C21H19ClN4O4	9823820	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0908		Leuprolide	C59H84N16O12	657181	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0909		Levacetylmethadol	C23H31NO2	15130	Moderate		Inter Info	[2], [3], [17]
D0942		Lofexidine	C11H12Cl2N2O	30668	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0948		Lopinavir	C37H48N4O5	92727	Moderate		Inter Info	[2], [3], [17]
D0960		Lumefantrine	C30H32Cl3NO	6437380	Moderate		Inter Info	[2], [3], [17]
D0095		Apalutamide	C21H15F4N5O2S	24872560	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0452		Deutetrabenazine	C19H27NO3	73437646	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0569		Encorafenib	C22H27ClFN7O4S	50922675	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0577		Entrectinib	C31H34F2N6O2	25141092	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0725		Glasdegib	C21H22N6O	25166913	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0872		Ivosidenib	C28H22ClF3N6O3	71657455	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0899		Lefamulin	C28H45NO5S	25185057	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1190		Osimertinib	C28H33N7O2	71496458	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1302		Pitolisant	C17H26ClNO	9948102	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1388		Relugolix	C29H27F2N7O5S	10348973	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1398		Ribociclib	C23H30N8O	44631912	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1474		Siponimod	C29H35F3N2O3	44599207	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1634		Triclabendazole	C14H9Cl3N2OS	50248	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1673		Valbenazine	C24H38N2O4	24795069	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1010		Mesoridazine	C21H26N2OS2	4078	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1017		Methadone	C21H27NO	4095	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1063		Mifepristone	C29H35NO2	55245	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1075		Mirtazapine	C17H19N3	4205	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1137		Nilutamide	C12H10F3N3O4	4493	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1181		Ondansetron	C18H19N3O	4595	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1210		Oxytocin	C43H66N12O12S2	439302	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1215		Paliperidone	C23H27FN4O3	115237	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1216		Palonosetron	C19H24N2O	6337614	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1221		Panobinostat	C21H23N3O2	6918837	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1230		Pasireotide	C58H66N10O9	9941444	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1246		Pentamidine	C19H24N4O2	4735	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1254		Perflutren	C3F8	6432	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1257		Perphenazine	C21H26ClN3OS	4748	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1290		Pimavanserin	C25H34FN3O2	10071196	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1292		Pimozide	C28H29F2N3O	16362	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1315		Posaconazole	C37H42F2N8O4	468595	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1339		Primaquine	C15H21N3O	4908	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1342		Probucol	C31H48O2S2	4912	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1343		Procainamide	C13H21N3O	4913	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1351		Promazine	C17H20N2S	4926	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1353		Propafenone	C21H27NO3	4932	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1356		Propofol	C12H18O	4943	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1383		Ranolazine	C24H33N3O4	56959	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[2], [3], [17]
D1444		Saquinavir	C38H50N6O5	441243	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1463		Sevoflurane	C4H3F7O	5206	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1491		Solifenacin	C23H26N2O2	154059	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1497		Sorafenib	C21H16ClF3N4O3	216239	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1498		Sotalol	C12H20N2O3S	5253	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1542		Telavancin	C80H106Cl2N11O27P	3081362	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1555		Terfenadine	C32H41NO2	5405	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1560		Tetrabenazine	C19H27NO3	6018	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1574		Thioridazine	C21H26N2S2	5452	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1612		Toremifene	C26H28ClNO	3005573	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1616		Tramadol	C16H25NO2	33741	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1624		Trazodone	C19H22ClN5O	5533	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1638		Triflupromazine	C18H19F3N2S	5568	Moderate		Inter Info	[15], [27], [58], [59], [60], [16], [61], [17]
D1651		Triptorelin	C64H82N18O13	25074470	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1681		Vandetanib	C22H24BrFN4O2	3081361	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[10], [2], [3], [15], [16], [17]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 23
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0012		Acetazolamide	C4H6N4O3S2	1986	Moderate		Inter Info	[16], [18], [19]
D0058		Amiloride	C6H8ClN7O	16231	Moderate		Inter Info	[16], [18], [19]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[16], [18], [19]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[16], [18], [19]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[16], [18], [19]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[16], [18], [19]
D0479		Diclofenamide	C6H6Cl2N2O4S2	3038	Moderate		Inter Info	[16], [18], [19]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[16], [18], [19]
D0771		Hydrochlorothiazide	C7H8ClN3O4S2	3639	Moderate		Inter Info	[16], [18], [19]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[16], [18], [19]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[16], [18], [19]
D0845		Irinotecan	C33H38N4O6	60838	Moderate		Inter Info	[118]
D0846		Irinotecan (liposomal)	C33H38N4O6	60838	Moderate		Inter Info	[118]
D0978		Mannitol	C6H14O6	6251	Moderate		Inter Info	[16], [18], [19]
D1018		Methazolamide	C5H8N4O3S2	4100	Moderate		Inter Info	[16], [18], [19]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[16], [18], [19]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[16], [18], [19]
D1501		Spironolactone	C24H32O4S	5833	Moderate		Inter Info	[16], [18], [19]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[16], [18], [19]
D1631		Triamterene	C12H11N7	5546	Moderate		Inter Info	[16], [18], [19]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[16], [18], [19]
D1668		Urea	CH4N2O	1176	Moderate		Inter Info	[16], [18], [19]
D0929		Linaclotide	C59H79N15O21S6	16158208	Minor		Inter Info	[219], [220]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0590		Erdafitinib	C25H30N6O2	67462786	Major		Inter Info	[5]

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225	Product Information. Iclusig (ponatinib). Ariad Pharmaceuticals Inc, Cambridge, MA.
226	Product Information. Ticlid (ticlopidine). Syntex Laboratories Inc, Palo Alto, CA.
227	Product Information. Erivedge (vismodegib). Genentech, South San Francisco, CA.

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