Details of Drug

Drug General Information (ID: D0877)
Drug Name	Kaolin
Drug Type	Natural product
Drug Synonymous	KAOLIN; 1332-58-7; China clay; Argilla; Porcelain clay; Bolus alba; White bole; Glomax; Light kaolin; Kaolin(superfine); Hydrated aluminum silicate; Kaolin clay slurry; Alphagloss; Altowhites; Alfaplate; Alphacoat; Altowhite; Apsilex; Argiflex; Bentone; Comalco; Electros; Emathlite; Hydrite; Kaopaous; Langford; Mcnamee; Parclay; Vanclay; Fitrol; Arcilla blanca; oxo-oxoalumanyloxy-[oxo(oxoalumanyloxy)silyl]oxysilane;dihydrate; Argilla alba; Comalco Kaolin; Osmo kaolin; Kaolin colloidal; beta Coat; Astra-Glaze; Snow tex; ASP Ultrafine; Kao-gel; Century HC; Kaophills-2; AA Kaolin; Clay (kaolin); Acidic white clays; BOL Blanc; ASP (mineral); Burgess 10; Airflo V 8; Amazon 88; Amazon 90; Argirec B 22; Argirec KN 15; Bilt Plate 156; Fitrol desiccite 25; Clays, white, acidic; Amazon Kaolin 855D; Kaolin [USP:JAN]; CB 1 (clay); CB 2 (clay); Clay 347; Metakaolin; Weisserton; Chishizhi; Kaolinum; Bolus; Natural kaolin; Red halloysite; Clay Nanopowder; Clay slurry; Heavy kaolin; Kaolin light; Kaolin Nanoclay; Nanoclay Powder; Alumina silicata; CCRIS 9288; HSDB 630; Kaolin, natural; Halloysitum rubrum; Perlite Clay Mix; Clay Nanoparticles; Kaolinum ponderosum; EPA Pesticide Chemical Code 100104; Expanded Perlite Powder; Perlite Nanoclay Powder; Halloysite Clay Nanotubes; Aluminum silicate hydroxide; Hydrated aluminium silicate; Aluminium silicate dihydrate; Aluminum Silicate (Hydrated); Nanoclay Montmorillonite 20A; Expanded Perlite Nanoparticles; Montmorillonite Bentonite Clay; Halloysite Nanotubes Properties; CHEMBL3833365; CHEBI:140503; Nanoclay Modified Asphalt Materials; Expanded Perlite Powder / Nanopowder; Shelsite 30B Montmorillonite Nanoparticles; FT-0627569; J-521617; 95077-05-7 Click to Show/Hide
Therapeutic Class	Herbal Products
Structure
Structure	3D Structure		2D Structure
Formula	Al2H4O9Si2
InChI	InChI=1S/2Al.O5Si2.2H2O.2O/c;;1-6(2)5-7(3)4;;;;/h;;;21H2;;/q2+1;-2;;;;
InChIKey	NLYAJNPCOHFWQQ-UHFFFAOYSA-N
Canonical SMILES	O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O
External Link
External Link	Pubchem ID	56841936

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM006 Pharmacodynamic additive effects BM003 Complex formation BM004 Adsorption BM009 Altered absorption (Unspecific) BM035 Additive antimotility effects BM038 Additive CNS depression effects
Relation Graph

Full list of drugs interacting with Kaolin
Affected gastrointestinal absorption
	Complex formation					Drug Num: 55
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0181		Bictegravir	C21H18F3N3O5	90311989	Major		Inter Info	[1], [2], [3]
D0515		Dolutegravir	C20H19F2N3O5	54726191	Major		Inter Info	[4]
D0034		Alendronic acid	C4H13NO7P2	2088	Moderate		Inter Info	[5], [6], [7]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[1], [2], [9], [10], [11], [12], [13], [14]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[15], [16], [17]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [15], [16], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [17], [43], [44], [45], [46]
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[52]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[53], [9], [54], [55], [56], [57], [58], [59], [60], [61], [37], [62], [46]
D0490		Digitoxin	C41H64O13	441207	Moderate		Inter Info	[63], [64], [65]
D0491		Digoxin	C41H64O14	2724385	Moderate		Inter Info	[63], [64], [66], [67], [65]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[53], [9], [54], [55], [56], [57], [58], [59], [60], [61], [37], [62], [46]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[15], [16], [17]
D0623		Etidronic acid	C2H8O7P2	3305	Moderate		Inter Info	[6], [68], [7]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[15], [16], [17]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [15], [16], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [17], [43], [44], [45], [46]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[15], [16], [17]
D0783		Ibandronate	C9H23NO7P2	60852	Moderate		Inter Info	[69], [70], [5], [6], [71], [7]
D0144		Baloxavir marboxil	C27H23F2N3O7S	124081896	Moderate		Inter Info	[72]
D0310		Chenodeoxycholic acid	C24H40O4	10133	Moderate		Inter Info	[73]
D0432		Deferasirox	C21H15N3O4	214348	Moderate		Inter Info	[74]
D0433		Deferiprone	C7H9NO2	2972	Moderate		Inter Info	[75]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [15], [16], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [17], [43], [44], [45], [46]
D0561		Eltrombopag	C25H22N4O4	135449332	Moderate		Inter Info	[2], [76]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[1], [2], [9], [10], [11], [12], [13], [14]
D1175		Omadacycline	C29H40N4O7	54697325	Moderate		Inter Info	[55], [58], [62]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[53], [9], [54], [55], [56], [57], [58], [59], [60], [61], [37], [62], [46]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [15], [16], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [17], [43], [44], [45], [46]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[15], [16], [17]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[53], [9], [54], [55], [56], [57], [58], [59], [60], [61], [37], [62], [46]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [15], [16], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [17], [43], [44], [45], [46]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[77]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[15], [16], [17]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [15], [16], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [17], [43], [44], [45], [46]
D1209		Oxytetracycline	C22H24N2O9	54675779	Moderate		Inter Info	[55], [58], [62]
D1245		Penicillamine	C5H11NO2S	5852	Moderate		Inter Info	[78], [79], [80], [81], [82], [83], [84], [37]
D1412		Risedronic acid	C7H11NO7P2	5245	Moderate		Inter Info	[5], [6], [7]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[15], [16], [17]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[53], [9], [54], [55], [56], [57], [58], [59], [60], [61], [37], [62], [46]
D1584		Tiludronic acid	C7H9ClO6P2S	60937	Moderate		Inter Info	[6], [68], [7]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[15], [16], [17]
D0010		Acebutolol	C18H28N2O4	1978	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D0117		Atenolol	C14H22N2O3	2249	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D0173		Betaxolol	C18H29NO3	2369	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D0188		Bisoprolol	C18H31NO4	2405	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D0265		Carteolol	C16H24N2O3	2583	Minor		Inter Info	[9], [89], [92]
D0267		Carvedilol	C24H26N2O4	2585	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D1114		Nebivolol	C22H25F2NO4	71301	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D0884		Labetalol	C19H24N2O3	3869	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D1049		Metoprolol	C15H25NO3	4171	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D1098		Nadolol	C17H27NO4	39147	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D1244		Penbutolol	C18H29NO2	37464	Minor		Inter Info	[9], [89], [92]
D1293		Pindolol	C14H20N2O2	4828	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D1357		Propranolol	C16H21NO2	4946	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D1498		Sotalol	C12H20N2O3S	5253	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
D1585		Timolol	C13H24N4O3S	33624	Minor		Inter Info	[9], [87], [88], [89], [90], [91], [92]
	Adsorption					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0123		Atropine	C17H23NO3	174174	Moderate		Inter Info	[2]
D0354		Clindamycin	C18H33ClN2O5S	446598	Moderate		Inter Info	[47], [48], [49], [50], [51]
D0931		Lincomycin	C18H34N2O6S	3000540	Moderate		Inter Info	[47], [48], [49], [50], [51]
D1350		Proguanil	C11H16ClN5	6178111	Moderate		Inter Info	[2], [85], [86]
D1354		Propantheline	C23H30NO3+	4934	Moderate		Inter Info	[1]
D1366		Pyrimethamine	C12H13ClN4	4993	Moderate		Inter Info	[2], [85]
	Altered absorption (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0040		Allopurinol	C5H4N4O	135401907	Moderate		Inter Info	[1], [2], [8]
D0489		Diflunisal	C13H8F2O3	3059	Minor		Inter Info	[9], [93], [94]
D0858		Isoniazid	C6H7N3O	3767	Minor		Inter Info	[95], [96]
Pharmacodynamic additive effects
	Additive antimotility effects					Drug Num: 15
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0226		Butorphanol	C21H29NO2	5361092	Moderate		Inter Info	[2]
D0379		Codeine	C18H21NO3	5284371	Moderate		Inter Info	[2]
D0467		Dextropropoxyphene	C22H29NO2	10100	Moderate		Inter Info	[2]
D0493		Dihydrocodeine	C18H23NO3	5284543	Moderate		Inter Info	[2]
D0772		Hydrocodone	C18H21NO3	5284569	Moderate		Inter Info	[2]
D0776		Hydromorphone	C17H19NO3	5284570	Moderate		Inter Info	[2]
D0909		Levacetylmethadol	C23H31NO2	15130	Moderate		Inter Info	[2]
D0923		Levorphanol	C17H23NO	5359272	Moderate		Inter Info	[2]
D1001		Meperidine	C15H21NO2	4058	Moderate		Inter Info	[2]
D1017		Methadone	C21H27NO	4095	Moderate		Inter Info	[2]
D1089		Morphine	C17H19NO3	5288826	Moderate		Inter Info	[2]
D1100		Nalbuphine	C21H27NO4	5311304	Moderate		Inter Info	[2]
D1203		Oxycodone	C18H21NO4	5284603	Moderate		Inter Info	[2]
D1208		Oxymorphone	C17H19NO4	5284604	Moderate		Inter Info	[2]
D1247		Pentazocine	C19H27NO	441278	Moderate		Inter Info	[2]
	Additive CNS depression effects					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0161		Benzhydrocodone	C25H25NO4	49836084	Moderate		Inter Info	[2]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[2]
D1183		Opium	NA	NA	Moderate		Inter Info	[2]

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