Drug General Information (ID: DDIC1DXOH0)
Drug Name			Propantheline		Drug Info		Kaolin		Drug Info
Drug Type		Small molecule				Natural product
Therapeutic Class		Antispasmodics				Herbal Products
Structure

Mechanism of Propantheline-Kaolin Interaction (Severity Level: Moderate)
Adsorption Click to Show/Hide Mechanism Graph
Drug Name		Propantheline				Kaolin
Mechanism		Adsorbed by adsorbent antidiarrheal agents				Adsorbent antidiarrheal agents
Key Mechanism Factor 1
		Factor Name		Adsorption
		Factor Description		Adsorption is a direct drug interaction, usually through adsorption on its surface, resulting in reduced absorption of concomitantly administered drugs in the gastrointestinal tract.
Mechanism Description		Decreased absorption of Propantheline due to adsorption of Kaolin

Recommended Action
Management		Antacids and absorbent antidiarrheals should be taken at least 2 to 3 hours apart from propantheline doses.

References
1	Cerner Multum, Inc. "Australian Product Information.".