Details of Drug

Drug General Information (ID: D0236)
Drug Name	Calcium carbonate
Drug Type	Small molecule
Drug Synonymous	Aragonite; CALCIUM CARBONATE; 471-34-1; Limestone; Calcite; Chalk; Carbonic acid calcium salt (1:1); Aeromatt; Calcium carbonate (1:1); Calofort U; Precipitated calcium carbonate; calciumcarbonate; Calcite (Ca(Co3)); 1317-65-3; CaCO3; Calciumcarbonat; Kalziumkarbonat; Calcium carbonate slurry; Calcium carbonate, powder; kohlensaurer Kalk; UNII-H0G9379FGK; carbonato de calcio; Chalk, Precipitated; carbonate de calcium; Marble; CI 77220; calcium trioxidocarbonate; Calcium carbonate [USP]; Carbonate (calcium); Kalkspar; CHEBI:3311; H0G9379FGK; MFCD00010906; Akadama; Albacar; Albafil; Albaglos; Atomite; Calcicoll; Calibrite; Calmote; Calseeds; Calwhite; Carbium; Chemcarb; Clefnon; Duramite; Hydrocarb; Kotamite; Microcarb; Micromya; Neoanticid; Atomit; Calmos; Caltec; Dacote; Marfil; Levigated chalk; Allied whiting; Tums; Marble white; Calcium carbonate (USP); Camel-carb; Camel-wite; Camel-tex; Britomya M; Britomya S; Calofort S; Calofort T; Calopake F; Calopake H; Hakuenka O; Multiflex MM; Multiflex SC; Albaglos SF; Calopake FS; Calopake PC; Carusis P; Garolite SA; Gilder's whiting; Hakuenka CC; Hakuenka DD; Hakuenka PX; Hakuenka PZ; Homocal D; Multifex MM; Neolite F; Calcene CO; Calcene NC; Calcene TM; Carbium MM; Hakuenka CCR; Neolite SP; Crystic prefil S; Neolite TPS; Calcilit 8; Carborex 2; Cal-Sup; Microwhite 25; R Jutan; Calcium Carbonate Nanopowder; Hakuenka T-DD; Brilliant 15; Filtex White Base; Hydrocarb 60; Hydrocarb 65; Marblewhite 325; Cal-Light SA; Calcidar 40; Carbital 90; Durcal 2NH; Non-Fer-Al; CCC G-white; Kredafil RM 5; Brilliant BR 15; Calofil A 4; Calofil B 1; Calofil E 2; C.I. Pigment White 18; Calcilit 100; Hakuenka R 06; Micromic CR 16; Calcium monocarbonate; Durcal 10; Durcal 40; Monocalcium carbonate; Brilliant 1500; Calofor U 50; Calopake high opacity; CCC No.AA oolitic; Eskalon 100; Eskalon 200; Eskalon 400; Eskalon 800; Finncarb 6002; C 50 (carbonate); Kredafil 150 Extra; Albacar 5970; Caswell No. 139; Eskalon 1500; MSK-PO; MSK-C; MSK-G; MSK-K; MSK-P; MSK-V; NCC-P; Slaker rejects; Marble dust; Mylanta soothing lozenges; Natural calcium carbonate; Oyster shell; Ground limestone; MC-T; Calcium, Reference Standard Solution; Durcal C 640305; P-Lite 500; P-Lite 700; Di-Gel Tablets; Carbonic Acid Calcium Salt; Precipitated chalk; EGRI M 5; Pigment white 18; KULU 40; Calcium carbonate, precipitated; BRT 30; CCRIS 1333; HSDB 927; NCC 45; Tylenol Headache Plus; BS 32; Vaterite (Ca(CO3)); BRT 1500; Carbonic acid, calcium salt (1:1); EINECS 207-439-9; AX 363; BF 200; KS 500; NS 100; NS 200; NS 400; EPA Pesticide Chemical Code 073502; KS 1300; KS 1500; KS 1800; KS 2100; NS 2500; Glauberitum; Calcitum; N 34; N 43; Caltan; Calcii carbonas; Kalk; Chalk Powder; Coral Calcium; Hydrolyzed pearl; Marble Chips; carbonate calcium; C.I. 77220; K 250; Han shui shi; Chalk, pure; Limestone, ground; calcium carb onate; Copper Nickel Foil; Marble, CP; Phx cal-carb buffer; T 130-2500; Cal-sup (TN); CCaO3; calcium(II) carbonate; Calcium carbonate, CP; Calcium (as carbonate); Calcium Carbonate,(S); Acid controller complete; Calcium Carbonate (AS); EC 207-439-9; SCHEMBL3261; Calcium Carbonate Dispersion; Calcium carbonate, technical; Precpitated calcium carbonate; Calcium Carbonate Granular DC; Calcium Carbonate Precipitated; Ca (C O3); Calcium (as calcium carbonate); Calcium Carbonate Nanoparticles; Calcium Carbonate Microparticles; CHEMBL1200539; DTXSID3036238; INS NO.170(I); NDI 443; Calcium carbonate, ReagentPlus(R); Calcium carbonate,puratronic powder; INS-170(I); Calcium carbonate, AR, >=98.5%; Calcium carbonate, LR, >=98.5%; AKOS015903256; Calcium carbonate, precipitated (JAN); Calcium carbonate, chelometric standard; Children's mylanta upset stomach relief; DB06724; Precipitated calcium carbonate (JP17); Calcium carbonate, BioXtra, >=99.0%; Calcium carbonate, Monocalcium carbonate; 13701-58-1; Calcium carbonate, powder A.C.S. reagent; E-170(I); E170; S266; Calcium carbonate, puriss. p.a., >=99%; Calcium carbonate, USP, 98.0-100.5%; Calcium carbonate, NIST(R) SRM(R) 915b; E 170; FT-0623383; Calcium carbonate (99.999%-Ca) PURATREM; C08129; Calcium carbonate, SAJ first grade, >=98.0%; Calcium carbonate, tested according to Ph.Eur.; D00932; Q23767; Calcium carbonate, 99.999% trace metals basis; Calcium carbonate, JIS special grade, >=99.5%; Calcium carbonate, p.a., 99.0%, ACS reagent; Calcium carbonate, >=99.995% trace metals basis; Calcium carbonate, Vetec(TM) reagent grade, 99%; Calcium carbonate, ACS reagent, >=99.0%, powder; Calcium carbonate, BioUltra, precipitated, >=99.0% (KT); Calcium carbonate, powder, <=30 mum particle size, 98%; Calcium carbonate, primary reference standard, 99.95-100.05%; NBS 18 (carbon isotopes in carbonatite), NIST(R) RM 8543; Calcium Carbonate, Trace metals grade 99.99% trace metals basis; Calcium Carbonate (AS), United States Pharmacopeia (USP) Reference Standard; Calcium carbonate, BioReagent, suitable for insect cell culture, >=99.0%; Calcium, Ion chromatography standard solution, Specpure?, Ca2+ 1000?g/ml; Calcium carbonate, ACS reagent, chelometric standard, 99.95-100.05% dry basis; Calcium carbonate, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%; Calcium carbonate, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), >=99%; Calcium carbonate, Pharmaceutical Secondary Standard; Certified Reference Material; Calcium carbonate, certified reference material for titrimetry, certified by BAM, according to ISO 17025, >=99.5%; Calcium carbonate, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E170, precipitated, 98.5-100.5% (based on anhydrous substance) Click to Show/Hide
Therapeutic Class	Antacids/Minerals And Electrolytes
Structure
Structure	3D Structure		2D Structure
Formula	CCaO3
InChI	InChI=1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
InChIKey	VTYYLEPIZMXCLO-UHFFFAOYSA-L
Canonical SMILES	C(=O)([O-])[O-].[Ca+2]
External Link
External Link	Pubchem ID	10112

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM003 Affected organization distribution AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM001 Altered gastrointestinal dynamics BM003 Complex formation BM004 Adsorption BM005 Altered gastric pH BM009 Altered absorption (Unspecific) BM014 Interference of cell/tissue uptake BM029 Altered urine pH BM089 Antagonize the effect of antihypertensive agents BM107 Attenuated pharmacological effects (Unspecific) BM108 Increased risk of hypercalcemia BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Calcium carbonate
Affected gastrointestinal absorption
	Altered gastrointestinal dynamics					Drug Num: 15
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0045		Alprazolam	C17H13ClN4	2118	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D0317		Chlordiazepoxide	C16H14ClN3O	2712	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D0356		Clobazam	C16H13ClN2O2	2789	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D0362		Clonazepam	C15H10ClN3O3	2802	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D0365		Clorazepic acid	C16H11ClN2O3	2809	Minor		Inter Info	[165], [166], [169]
D0473		Diazepam	C16H13ClN2O	3016	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D0604		Estazolam	C16H11ClN4	3261	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D0679		Flurazepam	C21H23ClFN3O	3393	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D0748		Halazepam	C17H12ClF3N2O	31640	Minor		Inter Info	[165], [166], [169]
D0951		Lorazepam	C15H10Cl2N2O2	3958	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D1060		Midazolam	C18H13ClFN3	4192	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D1197		Oxazepam	C15H11ClN2O2	4616	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D1367		Quazepam	C17H11ClF4N2S	4999	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D1547		Temazepam	C16H13ClN2O2	5391	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
D1632		Triazolam	C17H12Cl2N4	5556	Minor		Inter Info	[164], [165], [166], [167], [168], [169], [170], [171], [172]
	Complex formation					Drug Num: 43
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0181		Bictegravir	C21H18F3N3O5	90311989	Major		Inter Info	[1], [2], [3]
D0515		Dolutegravir	C20H19F2N3O5	54726191	Major		Inter Info	[4]
D1231		Patiromer	NA	NA	Major		Inter Info	[6], [7], [8]
D1377		Raltegravir	C20H21FN6O5	54671008	Major		Inter Info	[9], [1], [2], [10], [11], [12], [13]
D1605		Tolevamer	C11H16O3S	58817179	Major		Inter Info	[6], [7], [8]
D0034		Alendronic acid	C4H13NO7P2	2088	Moderate		Inter Info	[21], [22], [23]
D0144		Baloxavir marboxil	C27H23F2N3O7S	124081896	Moderate		Inter Info	[42]
D0433		Deferiprone	C7H9NO2	2972	Moderate		Inter Info	[50]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[51], [52], [53], [54], [55], [56], [33], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81]
D1175		Omadacycline	C29H40N4O7	54697325	Moderate		Inter Info	[89], [90], [91]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[18], [95], [96], [89], [97], [98], [90], [99], [100], [101], [71], [91], [81]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[104], [105], [106]
D1635		Triethylenetetramine	C6H18N4	5565	Moderate		Inter Info	[107]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[1], [2], [95], [112], [113], [114], [115], [116]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[63], [64], [77]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[51], [52], [53], [54], [55], [56], [33], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[18], [95], [96], [89], [97], [98], [90], [99], [100], [101], [71], [91], [81]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[18], [95], [96], [89], [97], [98], [90], [99], [100], [101], [71], [91], [81]
D0561		Eltrombopag	C25H22N4O4	135449332	Moderate		Inter Info	[2], [121]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[63], [64], [77]
D0623		Etidronic acid	C2H8O7P2	3305	Moderate		Inter Info	[22], [124], [23]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[63], [64], [77]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[51], [52], [53], [54], [55], [56], [33], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[63], [64], [77]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[1], [2], [95], [112], [113], [114], [115], [116]
D0783		Ibandronate	C9H23NO7P2	60852	Moderate		Inter Info	[129], [130], [21], [22], [131], [23]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[51], [52], [53], [54], [55], [56], [33], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81]
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[104], [105], [138], [106]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[104], [105], [138], [106]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Moderate		Inter Info	[104], [105], [106]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[63], [64], [77]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[18], [95], [96], [89], [97], [98], [90], [99], [100], [101], [71], [91], [81]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[51], [52], [53], [54], [55], [56], [33], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[145]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[63], [64], [77]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[51], [52], [53], [54], [55], [56], [33], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81]
D1209		Oxytetracycline	C22H24N2O9	54675779	Moderate		Inter Info	[89], [90], [91]
D1245		Penicillamine	C5H11NO2S	5852	Moderate		Inter Info	[151], [152], [153], [154], [155], [156], [157], [71]
D1412		Risedronic acid	C7H11NO7P2	5245	Moderate		Inter Info	[21], [22], [23]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[63], [64], [77]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[18], [95], [96], [89], [97], [98], [90], [99], [100], [101], [71], [91], [81]
D1584		Tiludronic acid	C7H9ClO6P2S	60937	Moderate		Inter Info	[22], [124], [23]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[63], [64], [77]
	Adsorption					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0123		Atropine	C17H23NO3	174174	Moderate		Inter Info	[2]
D1350		Proguanil	C11H16ClN5	6178111	Moderate		Inter Info	[2], [103], [158]
D1354		Propantheline	C23H30NO3+	4934	Moderate		Inter Info	[1]
D1366		Pyrimethamine	C12H13ClN4	4993	Moderate		Inter Info	[2], [103]
	Altered gastric pH					Drug Num: 68
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1459		Selpercatinib	C29H31N7O3	134436906	Major		Inter Info	[14]
D0013		Acetohexamide	C15H20N2O4S	1989	Moderate		Inter Info	[15], [16], [17]
D0074		Amphetamine	C9H13N	3007	Moderate		Inter Info	[27]
D0080		Amprenavir	C25H35N3O6S	65016	Moderate		Inter Info	[28], [29]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[30], [31], [32]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[33], [34]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[27]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[2], [38]
D0008		Acalabrutinib	C26H23N7O2	71226662	Moderate		Inter Info	[41]
D0184		Bisacodyl	C22H19NO4	2391	Moderate		Inter Info	[2]
D0229		Cabotegravir	C19H17F2N3O5	54713659	Moderate		Inter Info	[43]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[44]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[1], [2], [45], [46], [47], [48], [49]
D0898		Ledipasvir	C49H54F2N8O6	67505836	Moderate		Inter Info	[82]
D1124		Neratinib	C30H29ClN6O3	9915743	Moderate		Inter Info	[88]
D1258		Pexidartinib	C20H15ClF3N5	25151352	Moderate		Inter Info	[92]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[93]
D1408		Riociguat	C20H19FN8O2	11304743	Moderate		Inter Info	[94]
D1686		Velpatasvir	C49H54N8O8	67683363	Moderate		Inter Info	[108]
D0278		Cefditoren	C19H18N6O5S3	9870843	Moderate		Inter Info	[109]
D0288		Cefpodoxime	C15H17N5O6S2	6335986	Moderate		Inter Info	[33], [110], [111], [34]
D0297		Cefuroxime	C16H16N4O8S	5479529	Moderate		Inter Info	[33], [110], [111], [34]
D0325		Chlorpropamide	C10H13ClN2O3S	2727	Moderate		Inter Info	[15], [16], [17]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[117]
D0465		Dextroamphetamine	C9H13N	5826	Moderate		Inter Info	[27]
D0595		Erlotinib	C22H23N3O4	176870	Moderate		Inter Info	[1], [2], [122], [123]
D0727		Glimepiride	C24H34N4O5S	3476	Moderate		Inter Info	[125], [126], [127], [15], [16], [128], [17]
D0728		Glipizide	C21H27N5O4S	3478	Moderate		Inter Info	[125], [126], [127], [15], [16], [128], [17]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[125], [126], [127], [15], [16], [128], [17]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Moderate		Inter Info	[132], [133], [134], [43], [2], [135], [136], [137]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[27]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[139], [27], [140]
D1094		Mycophenolate mofetil	C23H31NO7	5281078	Moderate		Inter Info	[141], [142], [143], [144]
D1095		Mycophenolic acid	C17H20O6	446541	Moderate		Inter Info	[141], [142], [143], [144]
D1218		Pancrelipase	C8H8Na2O5	8519	Moderate		Inter Info	[1], [2], [103]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[2], [146], [147], [148], [149], [150]
D1430		Rosuvastatin	C22H28FN3O6S	446157	Moderate		Inter Info	[162]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Moderate		Inter Info	[163], [32]
D1601		Tolazamide	C14H21N3O3S	5503	Moderate		Inter Info	[15], [16], [17]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[15], [16], [17]
D0133		Axitinib	C22H18N4OS	6450551	Minor		Inter Info	[173]
D0156		Benazepril	C24H28N2O5	5362124	Minor		Inter Info	[174]
D0172		Betamethasone	C22H29FO5	9782	Minor		Inter Info	[175], [176], [177]
D1313		Ponatinib	C29H27F3N6O	24826799	Minor		Inter Info	[1], [178]
D1701		Vismodegib	C19H14Cl2N2O3S	24776445	Minor		Inter Info	[1], [2], [179]
D0254		Captopril	C9H15NO3S	44093	Minor		Inter Info	[174]
D0337		Cimetidine	C10H16N6S	2756	Minor		Inter Info	[180], [175], [181], [182], [183], [18], [184], [185], [186], [187], [188], [189]
D0539		Duloxetine	C18H19NOS	60835	Minor		Inter Info	[190]
D0567		Enalapril	C20H28N2O5	5388962	Minor		Inter Info	[174]
D0636		Famotidine	C8H15N7O2S3	5702160	Minor		Inter Info	[180], [175], [181], [182], [183], [18], [184], [185], [186], [187], [188], [189]
D0671		Fludrocortisone	C21H29FO5	31378	Minor		Inter Info	[175], [176], [177]
D0695		Fosinopril	C30H46NO7P	55891	Minor		Inter Info	[174]
D0773		Hydrocortisone	C21H30O5	5754	Minor		Inter Info	[175], [176], [177]
D0918		Levodopa	C9H11NO4	6047	Minor		Inter Info	[191], [192], [193], [194]
D0938		Lisinopril	C21H31N3O5	5362119	Minor		Inter Info	[174]
D1041		Methylprednisolone	C22H30O5	6741	Minor		Inter Info	[175], [176], [177]
D1082		Moexipril	C27H34N2O7	91270	Minor		Inter Info	[174]
D1151		Nizatidine	C12H21N5O2S2	3033637	Minor		Inter Info	[180], [175], [181], [182], [183], [18], [184], [185], [186], [187], [188], [189]
D1256		Perindopril	C19H32N2O5	107807	Minor		Inter Info	[174]
D1332		Prednisolone	C21H28O5	5755	Minor		Inter Info	[175], [176], [177]
D1334		Prednisone	C21H26O5	5865	Minor		Inter Info	[175], [176], [177]
D1369		Quinapril	C25H30N2O5	54892	Minor		Inter Info	[174]
D1379		Ramipril	C23H32N2O5	5362129	Minor		Inter Info	[174]
D1381		Ranitidine	C13H22N4O3S	3001055	Minor		Inter Info	[180], [175], [181], [182], [183], [18], [184], [185], [186], [187], [188], [189]
D1382		Ranitidine (bismuth citrate)	C13H22N4O3S	3001055	Minor		Inter Info	[180], [182], [18]
D1581		Ticlopidine	C14H14ClNS	5472	Minor		Inter Info	[195]
D1618		Trandolapril	C24H34N2O5	5484727	Minor		Inter Info	[174]
D1628		Triamcinolone	C21H27FO6	31307	Minor		Inter Info	[175], [176], [177]
	Altered absorption (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0439		Delavirdine	C22H28N6O3S	5625	Moderate		Inter Info	[118]
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1509		Strontium chloride Sr-89	Cl2Sr	5388879	Moderate		Inter Info	[1], [102], [103]
Affected excretion pathways
	Altered urine pH					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[18], [19], [20]
D1020		Methenamine	C6H12N4	4101	Moderate		Inter Info	[83], [84], [85], [86], [87]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[159], [160], [161]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[18], [19], [20]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[18], [19], [20]
Pharmacodynamic additive effects
	Increased risk of hypercalcemia					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0158		Bendroflumethiazide	C15H14F3N3O4S2	2315	Moderate		Inter Info	[35], [36], [37]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[35], [36], [37]
D1753		Calcipotriol (topical)	C27H40O3	5288783	Moderate		Inter Info	[39], [40]
D1754		Calcitriol (topical)	C27H44O3	5280453	Moderate		Inter Info	[39], [40]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[35], [36], [37]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[35], [36], [37]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[35], [36], [37]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[35], [36], [37]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[35], [36], [37]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[35], [36], [37]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[35], [36], [37]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0490		Digitoxin	C41H64O13	441207	Moderate		Inter Info	[102], [119], [120]
D0491		Digoxin	C41H64O14	2724385	Moderate		Inter Info	[102], [119], [120]
Pharmacodynamic antagonistic effects
	Antagonize the effect of antihypertensive agents					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0069		Amlodipine	C20H25ClN2O5	2162	Moderate		Inter Info	[24], [25], [26]
D0170		Bepridil	C24H34N2O	2351	Moderate		Inter Info	[24], [25], [26]
D0911		Levamlodipine	C20H25ClN2O5	9822750	Moderate		Inter Info	[24], [25], [26]
D0497		Diltiazem	C22H26N2O4S	39186	Moderate		Inter Info	[24], [25], [26]
D0640		Felodipine	C18H19Cl2NO4	3333	Moderate		Inter Info	[24], [25], [26]
D0865		Isradipine	C19H21N3O5	3784	Moderate		Inter Info	[24], [25], [26]
D1130		Nicardipine	C26H29N3O6	4474	Moderate		Inter Info	[24], [25], [26]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[24], [25], [26]
D1138		Nimodipine	C21H26N2O7	4497	Moderate		Inter Info	[24], [25], [26]
D1141		Nisoldipine	C20H24N2O6	4499	Moderate		Inter Info	[24], [25], [26]
D1690		Verapamil	C27H38N2O4	2520	Moderate		Inter Info	[24], [25], [26]
	Attenuated pharmacological effects (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0590		Erdafitinib	C25H30N6O2	67462786	Major		Inter Info	[5]

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