Drug General Information (ID: D0479)
  Drug Name
Diclofenamide
  Drug Type Small molecule
  Drug Synonymous
dichlorphenamide; Diclofenamide; 120-97-8; 4,5-dichlorobenzene-1,3-disulfonamide; Dichlofenamide; Dichlorophenamide; Daranide; Dichlorphenamid; Glauconide; Antidrasi; Glaucol; Oratrol; Diclofenamidum; Diclofenamida; Diclofenamid; Barastonin; Glaumid; Glafco; Glajust; 4,5-Dichloro-m-benzenedisulfonamide; 1,3-Benzenedisulfonamide, 4,5-dichloro-; Diclofenamidum [INN-Latin]; 4,5-Dichloro-1,3-disulfamoylbenzene; 1,3-Disulfamoyl-4,5-dichlorobenzene; Diclofenamida [INN-Spanish]; 1,3-Disulfamyl-4,5-dichlorobenzene; Dasanide; Keveyis; Antidrasi; Dichlorphenamide [BAN]; Llorens Brand of Dichlorphenamide; Merck Brand of Dichlorphenamide; CB 8000; I7A; Daranide (TN); Dichlorophenamide (DCP); Dichlorphenamide (USP); Diclofenamide (JP15/INN); 3,4-Dichloro-5-sulfamylbenzenesulfonamide; 4,5-Dichloro-1,3-benzenedisulfonamide; 4,5-Dichloro-benzene-1,3-disulfonic acid diamide; 4,5-DICHLOROBENZENE-1,3-DISULFONAMIDE
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  Disease Class 9C61: Glaucoma
  Therapeutic Class Ophthalmic Glaucoma Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C6H6Cl2N2O4S2
  InChI 1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14)
  InChIKey GJQPMPFPNINLKP-UHFFFAOYSA-N
  Canonical SMILES C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
  External Link
Pubchem ID 3038
CAS Number 120-97-8
CHEBI ID 101085
TTD ID D0J4GO

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
AM003  Affected organization distribution
AM005  Affected excretion pathways
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM009  Altered absorption (Unspecific)
BM013  Competitive binding of plasma proteins
BM014  Interference of cell/tissue uptake
BM029  Altered urine pH
BM038  Additive CNS depression effects
BM042  Additive hypotensive effects
BM044  Additive myelosuppressive effects
BM045  Additive neuromuscular blocking effects
BM065  Increased risk of hypokalemia
BM066  Increased risk of hypomagnesemia
BM067  Increased risk of hyponatremia
BM070  Increased risk of metabolic acidosis
BM072  Increased risk of nephrotoxicity
BM081  Increased risk of ventricular arrhythmias
BM086  Antagonize the effect of antidiabetic agents
BM089  Antagonize the effect of antihypertensive agents
BM107  Attenuated pharmacological effects (Unspecific)
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Diclofenamide
      Affected gastrointestinal absorption
   Altered absorption (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1340
 
Primidone
 
C12H14N2O2
 
4909 
Moderate    Inter Info   
[88]
      Affected organization distribution
   Competitive binding of plasma proteins Drug Num:  5
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Major    Inter Info   
[4], [5], [6]
D0187
 
Bismuth subsalicylate
 
C7H6BiO4
 
16682734 
Major    Inter Info   
[4], [5], [6]
D0331
 
Choline salicylate
 
C12H19NO4
 
54686350 
Major    Inter Info   
[4], [5], [6]
D1442
 
Salsalate
 
C14H10O5
 
5161 
Major    Inter Info   
[4], [5], [6]
D1439
 
Salicylic acid (sodium)
 
C7H6O3
 
338 
Major    Inter Info   
[4], [5], [6]
   Interference of cell/tissue uptake Drug Num:  2
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1818
 
Indium In-111 pentetate
 
C14H20InN3O10
 
76967078 
Moderate    Inter Info   
[72]
D0326
 
Chlorthalidone
 
C14H11ClN2O4S
 
2732 
Minor    Inter Info   
[93], [94]
      Affected excretion pathways
   Altered urine pH Drug Num:  3
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1020
 
Methenamine
 
C6H12N4
 
4101 
Moderate    Inter Info   
[77], [78], [79]
D1371
 
Quinidine
 
C20H24N2O2
 
441074 
Moderate    Inter Info   
[89], [90], [91]
D0998
 
Memantine
 
C12H21N
 
4054 
Minor    Inter Info   
[100]
      Pharmacodynamic additive effects
   Additive CNS depression effects Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1596
 
Tizanidine
 
C9H8ClN5S
 
5487 
Moderate    Inter Info   
[29], [92], [27]
   Additive hypotensive effects Drug Num:  25
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0030
 
Aldesleukin
 
NA
 
NA
Moderate    Inter Info   
[33]
D0097
 
Apomorphine
 
C17H17NO2
 
6005 
Moderate    Inter Info   
[38], [39], [40]
D0156
 
Benazepril
 
C24H28N2O5
 
5362124 
Moderate    Inter Info   
[44], [45], [46]
D0128
 
Avanafil
 
C23H26ClN7O3
 
9869929 
Moderate    Inter Info   
[60], [61], [62]
D0254
 
Captopril
 
C9H15NO3S
 
44093 
Moderate    Inter Info   
[44], [45], [46]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Moderate    Inter Info   
[37], [69], [70]
D0918
 
Levodopa
 
C9H11NO4
 
6047 
Moderate    Inter Info   
[38], [39], [73]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Moderate    Inter Info   
[27], [80], [29]
D1148
 
Nitrous acid
 
HNO2
 
24529 
Moderate    Inter Info   
[81], [82], [83]
D1457
 
Selexipag
 
C26H32N4O4S
 
9913767 
Moderate    Inter Info   
[37], [69], [70]
D0567
 
Enalapril
 
C20H28N2O5
 
5388962 
Moderate    Inter Info   
[44], [45], [46]
D0644
 
Fenoldopam
 
C16H16ClNO3
 
3341 
Moderate    Inter Info   
[18], [87]
D0695
 
Fosinopril
 
C30H46NO7P
 
55891 
Moderate    Inter Info   
[44], [45], [46]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Moderate    Inter Info   
[37], [69], [70]
D0938
 
Lisinopril
 
C21H31N3O5
 
5362119 
Moderate    Inter Info   
[44], [45], [46]
D1082
 
Moexipril
 
C27H34N2O7
 
91270 
Moderate    Inter Info   
[44], [45], [46]
D1256
 
Perindopril
 
C19H32N2O5
 
107807 
Moderate    Inter Info   
[44], [45], [46]
D1369
 
Quinapril
 
C25H30N2O5
 
54892 
Moderate    Inter Info   
[44], [45], [46]
D1379
 
Ramipril
 
C23H32N2O5
 
5362129 
Moderate    Inter Info   
[44], [45], [46]
D1465
 
Sildenafil
 
C22H30N6O4S
 
135398744 
Moderate    Inter Info   
[60], [61], [62]
D1618
 
Trandolapril
 
C24H34N2O5
 
5484727 
Moderate    Inter Info   
[44], [45], [46]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Moderate    Inter Info   
[37], [69], [70]
D1682
 
Vardenafil
 
C23H32N6O4S
 
135400189 
Moderate    Inter Info   
[60], [61], [62]
D0711
 
Garlic
 
NA
 
NA
Minor    Inter Info   
[98], [99]
D1527
 
Tadalafil
 
C22H19N3O4
 
110635 
Minor    Inter Info   
[101], [102]
   Additive myelosuppressive effects Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0370
 
Clozapine
 
C18H19ClN4
 
135398737 
Moderate    Inter Info   
[1], [27], [53]
   Additive neuromuscular blocking effects Drug Num:  12
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0343
 
Cisatracurium
 
C53H72N2O12+2
 
62887 
Moderate    Inter Info   
[47], [48], [49]
D0122
 
Atracurium
 
C53H72N2O12+2
 
47319 
Moderate    Inter Info   
[47], [48], [49]
D1047
 
Metocurine
 
C40H48N2O6+2
 
21233 
Moderate    Inter Info   
[47], [48], [49]
D1080
 
Mivacurium
 
C58H80N2O14+2
 
5281042 
Moderate    Inter Info   
[47], [48], [49]
D1219
 
Pancuronium
 
C35H60N2O4+2
 
441289 
Moderate    Inter Info   
[47], [48], [49]
D1295
 
Pipecuronium
 
C35H62N4O4+2
 
50192 
Moderate    Inter Info   
[47], [48], [49]
D1384
 
Rapacuronium
 
C37H61N2O4+
 
5311399 
Moderate    Inter Info   
[47], [48], [49]
D1659
 
Tubocurarine
 
C37H41N2O6+
 
6000 
Moderate    Inter Info   
[47], [48], [49]
D1684
 
Vecuronium
 
C34H57N2O4+
 
39765 
Moderate    Inter Info   
[47], [48], [49]
D0522
 
Doxacurium
 
C56H78N2O16+2
 
60169 
Moderate    Inter Info   
[47], [48], [49]
D1420
 
Rocuronium
 
C32H53N2O4+
 
441290 
Moderate    Inter Info   
[47], [48], [49]
D1510
 
Succinylcholine
 
C14H30N2O4+2
 
5314 
Moderate    Inter Info   
[47], [48], [49]
   Increased risk of hypokalemia Drug Num:  29
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0075
 
Amphotericin B
 
C47H73NO17
 
5280965 
Moderate    Inter Info   
[37]
D0077
 
Amphotericin B (lipid complex)
 
C47H73NO17
 
5280965 
Moderate    Inter Info   
[37]
D0078
 
Amphotericin B (liposomal)
 
C47H73NO17
 
5280965 
Moderate    Inter Info   
[37]
D0148
 
Beclomethasone dipropionate
 
C28H37ClO7
 
21700 
Moderate    Inter Info   
[41], [42], [43]
D0172
 
Betamethasone
 
C22H29FO5
 
9782 
Moderate    Inter Info   
[41], [42], [43]
D0103
 
Arformoterol
 
C19H24N2O4
 
3083544 
Moderate    Inter Info   
[57], [58], [59]
D0392
 
Corticotropin
 
C207H308N56O58S
 
16132265 
Moderate    Inter Info   
[41], [42], [43]
D0436
 
Deflazacort
 
C25H31NO6
 
189821 
Moderate    Inter Info   
[41], [42], [43]
D0453
 
Dexamethasone
 
C22H29FO5
 
5743 
Moderate    Inter Info   
[41], [42], [43]
D0490
 
Digitoxin
 
C41H64O13
 
441207 
Moderate    Inter Info   
[66], [67], [68]
D0797
 
Indacaterol
 
C24H28N2O3
 
6918554 
Moderate    Inter Info   
[57], [58], [59]
D0924
 
Levosalbutamol
 
C13H21NO3
 
123600 
Moderate    Inter Info   
[57], [58], [59]
D0926
 
Licorice
 
C42H62O16Zn
 
163463 
Moderate    Inter Info   
[74], [75], [76]
D1171
 
Olodaterol
 
C21H26N2O5
 
11504295 
Moderate    Inter Info   
[57], [58], [59]
D1298
 
Pirbuterol
 
C12H20N2O3
 
4845 
Moderate    Inter Info   
[57], [58], [59]
D1563
 
Tetracosactide
 
C136H210N40O31S
 
16133802 
Moderate    Inter Info   
[41], [42], [43]
D1695
 
Vilanterol
 
C24H33Cl2NO5
 
10184665 
Moderate    Inter Info   
[57], [58], [59]
D0491
 
Digoxin
 
C41H64O14
 
2724385 
Moderate    Inter Info   
[66], [67], [68]
D0671
 
Fludrocortisone
 
C21H29FO5
 
31378 
Moderate    Inter Info   
[41], [42], [43]
D0691
 
Formoterol
 
C19H24N2O4
 
3410 
Moderate    Inter Info   
[57], [58], [59]
D0773
 
Hydrocortisone
 
C21H30O5
 
5754 
Moderate    Inter Info   
[41], [42], [43]
D1041
 
Methylprednisolone
 
C22H30O5
 
6741 
Moderate    Inter Info   
[41], [42], [43]
D1185
 
Orciprenaline
 
C11H17NO3
 
4086 
Moderate    Inter Info   
[57], [58], [59]
D1332
 
Prednisolone
 
C21H28O5
 
5755 
Moderate    Inter Info   
[41], [42], [43]
D1334
 
Prednisone
 
C21H26O5
 
5865 
Moderate    Inter Info   
[41], [42], [43]
D1438
 
Salbutamol
 
C13H21NO3
 
2083 
Moderate    Inter Info   
[57], [58], [59]
D1440
 
Salmeterol
 
C25H37NO4
 
5152 
Moderate    Inter Info   
[57], [58], [59]
D1554
 
Terbutaline
 
C12H19NO3
 
5403 
Moderate    Inter Info   
[57], [58], [59]
D1628
 
Triamcinolone
 
C21H27FO6
 
31307 
Moderate    Inter Info   
[41], [42], [43]
   Increased risk of hyponatremia Drug Num:  14
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Moderate    Inter Info   
[50], [51], [52]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Moderate    Inter Info   
[50], [51], [52]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Moderate    Inter Info   
[50], [51], [52]
D0601
 
Eslicarbazepine
 
C15H14N2O2
 
9881504 
Moderate    Inter Info   
[71]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Moderate    Inter Info   
[50], [51], [52]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Moderate    Inter Info   
[50], [51], [52]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Moderate    Inter Info   
[50], [51], [52]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Moderate    Inter Info   
[50], [51], [52]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Moderate    Inter Info   
[50], [51], [52]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Moderate    Inter Info   
[50], [52], [51]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[50], [51], [52]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Moderate    Inter Info   
[50], [51], [52]
D1464
 
Sibutramine
 
C17H26ClN
 
5210 
Moderate    Inter Info   
[50], [52], [51]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Moderate    Inter Info   
[50], [51], [52]
   Increased risk of metabolic acidosis Drug Num:  5
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0012
 
Acetazolamide
 
C4H6N4O3S2
 
1986 
Major    Inter Info   
[1], [2], [3]
D1015
 
Metformin
 
C4H11N5
 
4091 
Major    Inter Info   
[23], [24], [25]
D1018
 
Methazolamide
 
C5H8N4O3S2
 
4100 
Major    Inter Info   
[1], [2], [3]
D1609
 
Topiramate
 
C12H21NO8S
 
5284627 
Major    Inter Info   
[1], [2], [3]
D1730
 
Zonisamide
 
C8H8N2O3S
 
5734 
Major    Inter Info   
[1], [2], [3]
   Increased risk of nephrotoxicity Drug Num:  14
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0472
 
Diatrizoate
 
C11H9I3N2O4
 
2140 
Moderate    Inter Info   
[54], [55], [56]
D0831
 
Iodipamide
 
C20H14I6N2O6
 
3739 
Moderate    Inter Info   
[54], [55], [56]
D0832
 
Iodixanol
 
C35H44I6N6O15
 
3724 
Moderate    Inter Info   
[54], [55], [56]
D0833
 
Iohexol
 
C19H26I3N3O9
 
3730 
Moderate    Inter Info   
[54], [55], [56]
D0834
 
Iopamidol
 
C17H22I3N3O8
 
65492 
Moderate    Inter Info   
[54], [55], [56]
D0836
 
Iopromide
 
C18H24I3N3O8
 
3736 
Moderate    Inter Info   
[54], [55], [56]
D0837
 
Iothalamic acid
 
C11H9I3N2O4
 
3737 
Moderate    Inter Info   
[54], [55], [56]
D0838
 
Ioversol
 
C18H24I3N3O9
 
3741 
Moderate    Inter Info   
[54], [55], [56]
D0839
 
Ioxilan
 
C18H24I3N3O8
 
3743 
Moderate    Inter Info   
[54], [55], [56]
D0441
 
Demeclocycline
 
C21H21ClN2O8
 
54680690 
Minor    Inter Info   
[95], [96], [97]
D0530
 
Doxycycline
 
C22H24N2O8
 
54671203 
Minor    Inter Info   
[95], [96], [97]
D1070
 
Minocycline
 
C23H27N3O7
 
54675783 
Minor    Inter Info   
[95], [96], [97]
D1209
 
Oxytetracycline
 
C22H24N2O9
 
54675779 
Minor    Inter Info   
[95], [96], [97]
D1564
 
Tetracycline
 
C22H24N2O8
 
54675776 
Minor    Inter Info   
[95], [96], [97]
   Increased risk of ventricular arrhythmias Drug Num:  9
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0066
 
Amiodarone
 
C25H29I2NO3
 
2157 
Major    Inter Info   
[7], [8], [9]
D0342
 
Cisapride
 
C23H29ClFN3O4
 
6917698 
Major    Inter Info   
[10], [11], [12]
D0107
 
Arsenic trioxide
 
As2O3
 
14888 
Major    Inter Info   
[13], [14]
D0534
 
Dronedarone
 
C31H44N2O5S
 
208898 
Major    Inter Info   
[15]
D0909
 
Levacetylmethadol
 
C23H31NO2
 
15130 
Major    Inter Info   
[16], [17], [18]
D0513
 
Dofetilide
 
C19H27N3O5S2
 
71329 
Major    Inter Info   
[19]
D0535
 
Droperidol
 
C22H22FN3O2
 
3168 
Major    Inter Info   
[20], [21], [22]
D1292
 
Pimozide
 
C28H29F2N3O
 
16362 
Major    Inter Info   
[10], [26]
D1726
 
Ziprasidone
 
C21H21ClN4OS
 
60854 
Major    Inter Info   
[27], [28], [29]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  14
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0184
 
Bisacodyl
 
C22H19NO4
 
2391 
Moderate    Inter Info   
[63], [64], [65]
D0269
 
Castor oil
 
C57H104O9
 
14030006 
Moderate    Inter Info   
[63], [64], [65]
D0701
 
Frangula purshiana bark
 
NA
 
NA
Moderate    Inter Info   
[63], [64], [65]
D0731
 
Glycerin
 
C3H8O3
 
753 
Moderate    Inter Info   
[63], [64], [65]
D0887
 
Lactitol
 
C12H24O11
 
157355 
Moderate    Inter Info   
[63], [64], [65]
D0970
 
Magnesium citrate
 
C12H10Mg3O14
 
6099959 
Moderate    Inter Info   
[63], [64], [65]
D0973
 
Magnesium hydroxide
 
H2MgO2
 
14791 
Moderate    Inter Info   
[63], [64], [65]
D1069
 
Mineral oil
 
NA
 
NA
Moderate    Inter Info   
[63], [64], [65]
D1266
 
Phenolphthalein
 
C20H14O4
 
4764 
Moderate    Inter Info   
[63], [64], [65]
D1287
 
Picosulfuric acid
 
C18H15NO8S2
 
5243 
Moderate    Inter Info   
[84], [85], [86]
D1308
 
Polyethylene glycol (3350 with electrolytes)
 
C2H6O2
 
174 
Moderate    Inter Info   
[84], [85], [86]
D1309
 
Polyethylene glycol (3350)
 
C2H6O2
 
174 
Moderate    Inter Info   
[63], [64], [65]
D1488
 
Sodium sulfate
 
Na2O4S
 
24436 
Moderate    Inter Info   
[84], [85], [86]
D0888
 
Lactulose
 
C12H22O11
 
11333 
Moderate    Inter Info   
[63], [64], [65]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of antidiabetic agents Drug Num:  39
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0009
 
Acarbose
 
C25H43NO18
 
41774 
Moderate    Inter Info   
[30], [31], [32]
D0013
 
Acetohexamide
 
C15H20N2O4S
 
1989 
Moderate    Inter Info   
[30], [31], [32]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Moderate    Inter Info   
[30], [31], [32]
D0029
 
Albiglutide
 
C148H224N40O45
 
145994868 
Moderate    Inter Info   
[30], [31], [32]
D0042
 
Alogliptin
 
C18H21N5O2
 
11450633 
Moderate    Inter Info   
[30], [31], [32]
D0245
 
Canagliflozin
 
C24H25FO5S
 
24812758 
Moderate    Inter Info   
[30], [31], [32]
D0418
 
Dapagliflozin
 
C21H25ClO6
 
9887712 
Moderate    Inter Info   
[30], [31], [32]
D0565
 
Empagliflozin
 
C23H27ClO7
 
11949646 
Moderate    Inter Info   
[30], [31], [32]
D0807
 
Insulin aspart (aspart protamine)
 
C256H381N65O79S6
 
118984445 
Moderate    Inter Info   
[30], [31], [32]
D0808
 
Insulin aspart (aspart)
 
C256H381N65O79S6
 
118984445 
Moderate    Inter Info   
[30], [31], [32]
D0809
 
Insulin degludec
 
C274H411N65O81S6
 
118984462 
Moderate    Inter Info   
[30], [31], [32]
D0810
 
Insulin detemir
 
C267H402N64O76S6
 
16137271 
Moderate    Inter Info   
[30], [31], [32]
D0812
 
Insulin glulisine
 
C258H384N64O78S6
 
16136701 
Moderate    Inter Info   
[30], [31], [32]
D0930
 
Linagliptin
 
C25H28N8O2
 
10096344 
Moderate    Inter Info   
[30], [31], [32]
D0936
 
Liraglutide
 
C172H265N43O51
 
16134956 
Moderate    Inter Info   
[30], [31], [32]
D0941
 
Lixisenatide
 
C215H347N61O65S
 
90472060 
Moderate    Inter Info   
[30], [31], [32]
D1326
 
Pramlintide
 
C171H267N51O53S2
 
70691388 
Moderate    Inter Info   
[30], [31], [32]
D1449
 
Saxagliptin
 
C18H25N3O2
 
11243969 
Moderate    Inter Info   
[30], [31], [32]
D1477
 
Sitagliptin
 
C16H15F6N5O
 
4369359 
Moderate    Inter Info   
[30], [31], [32]
D0727
 
Glimepiride
 
C24H34N4O5S
 
3476 
Moderate    Inter Info   
[30], [31], [32]
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Moderate    Inter Info   
[30], [31], [32]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Moderate    Inter Info   
[30], [31], [32]
D0811
 
Insulin glargine
 
C267H404N72O78S6
 
118984454 
Moderate    Inter Info   
[30], [31], [32]
D0813
 
Insulin human
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[30], [31], [32]
D0814
 
Insulin human (inhalation, rapid acting)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[30], [31], [32]
D0815
 
Insulin human (isophane)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[30], [31], [32]
D0816
 
Insulin human (regular)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[30], [31], [32]
D0817
 
Insulin human (zinc extended)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[30], [31], [32]
D0818
 
Insulin human (zinc)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[30], [31], [32]
D0819
 
Insulin lispro
 
C257H389N65O77S6
 
16132438 
Moderate    Inter Info   
[30], [31], [32]
D0820
 
Insulin lispro (protamine)
 
C257H389N65O77S6
 
16132438 
Moderate    Inter Info   
[30], [31], [32]
D1064
 
Miglitol
 
C8H17NO5
 
441314 
Moderate    Inter Info   
[30], [31], [32]
D1112
 
Nateglinide
 
C19H27NO3
 
5311309 
Moderate    Inter Info   
[30], [31], [32]
D1294
 
Pioglitazone
 
C19H20N2O3S
 
4829 
Moderate    Inter Info   
[30], [31], [32]
D1392
 
Repaglinide
 
C27H36N2O4
 
65981 
Moderate    Inter Info   
[30], [31], [32]
D1429
 
Rosiglitazone
 
C18H19N3O3S
 
77999 
Moderate    Inter Info   
[30], [31], [32]
D1601
 
Tolazamide
 
C14H21N3O3S
 
5503 
Moderate    Inter Info   
[30], [31], [32]
D1603
 
Tolbutamide
 
C12H18N2O3S
 
5505 
Moderate    Inter Info   
[30], [31], [32]
D1652
 
Troglitazone
 
C24H27NO5S
 
5591 
Moderate    Inter Info   
[30], [31], [32]
   Antagonize the effect of antihypertensive agents Drug Num:  3
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1779
 
Dulaglutide
 
NA
 
NA
Moderate    Inter Info   
[30], [31], [32]
D1782
 
Ertugliflozin
 
C22H25ClO7
 
44814423 
Moderate    Inter Info   
[30], [31], [32]
D1887
 
Semaglutide
 
C187H291N45O59
 
56843331 
Moderate    Inter Info   
[30], [31], [32]
   Attenuated pharmacological effects (Unspecific) Drug Num:  16
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0045
 
Alprazolam
 
C17H13ClN4
 
2118 
Moderate    Inter Info   
[34], [35], [36]
D0317
 
Chlordiazepoxide
 
C16H14ClN3O
 
2712 
Moderate    Inter Info   
[34], [35], [36]
D0356
 
Clobazam
 
C16H13ClN2O2
 
2789 
Moderate    Inter Info   
[34], [35], [36]
D0362
 
Clonazepam
 
C15H10ClN3O3
 
2802 
Moderate    Inter Info   
[34], [35], [36]
D0365
 
Clorazepic acid
 
C16H11ClN2O3
 
2809 
Moderate    Inter Info   
[34], [35], [36]
D0473
 
Diazepam
 
C16H13ClN2O
 
3016 
Moderate    Inter Info   
[34], [35], [36]
D0604
 
Estazolam
 
C16H11ClN4
 
3261 
Moderate    Inter Info   
[34], [35], [36]
D1367
 
Quazepam
 
C17H11ClF4N2S
 
4999 
Moderate    Inter Info   
[34], [35], [36]
D1391
 
Remimazolam
 
C21H19BrN4O2
 
9867812 
Moderate    Inter Info   
[34], [35], [36]
D0679
 
Flurazepam
 
C21H23ClFN3O
 
3393 
Moderate    Inter Info   
[34], [35], [36]
D0748
 
Halazepam
 
C17H12ClF3N2O
 
31640 
Moderate    Inter Info   
[34], [35], [36]
D0951
 
Lorazepam
 
C15H10Cl2N2O2
 
3958 
Moderate    Inter Info   
[34], [35], [36]
D1060
 
Midazolam
 
C18H13ClFN3
 
4192 
Moderate    Inter Info   
[34], [35], [36]
D1197
 
Oxazepam
 
C15H11ClN2O2
 
4616 
Moderate    Inter Info   
[34], [35], [36]
D1547
 
Temazepam
 
C16H13ClN2O2
 
5391 
Moderate    Inter Info   
[34], [35], [36]
D1632
 
Triazolam
 
C17H12Cl2N4
 
5556 
Moderate    Inter Info   
[34], [35], [36]
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