| Mechanism of Cisapride-Diclofenamide Interaction
(Severity Level: Major)
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Increased risk of ventricular arrhythmias
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| Drug Name |
Cisapride |
Diclofenamide |
| Mechanism 1 |
Prolong QT interval |
Hypokalemia |
| Key Mechanism Factor 1 |
| Factor Name |
Ventricular arrhythmias |
| Factor Description |
Ventricular arrhythmias are abnormal heart rhythms that cause your heart's lower chambers to pump blood instead of pumping it. This can limit or stop your heart from supplying blood to your body. While some of these arrhythmias are harmless and do not cause symptoms, others can have serious, even fatal, effects on your body. |
| Mechanism Description |
- Increased risk of ventricular arrhythmias by the combination of Cisapride and Diclofenamide
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| Mechanism 2 |
Prolong QT interval |
Hypomagnesemia |
| Key Mechanism Factor 2 |
| Factor Name |
Ventricular arrhythmias |
| Factor Description |
Ventricular arrhythmias are abnormal heart rhythms that cause your heart's lower chambers to pump blood instead of pumping it. This can limit or stop your heart from supplying blood to your body. While some of these arrhythmias are harmless and do not cause symptoms, others can have serious, even fatal, effects on your body. |
| Mechanism Description |
- Increased risk of ventricular arrhythmias by the combination of Cisapride and Diclofenamide
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