Details of Drug

Drug General Information (ID: D0974)
Drug Name	Magnesium oxide
Drug Type	Small molecule
Drug Synonymous	1309-48-4; Magnesia; oxomagnesium; Periclase; Magnesium oxide (MgO); Seawater magnesia; Magnesium oxide fume; Heavy magnesium oxide; Uro-Mag; 1317-74-4; Magnesium oxide, heavy; MFCD00011109; Magnesium oxide, -325 mesh; Magnesia grooves; Causmag; Granmag; Maglite; Seasorb; Animag; Magcal; Marmag; Oxymag; Heavy magnesia; Light magnesia; BayMag; Maglite de; Calcined brucite; Magnesa preprata; Akro-mag; Liquimag A; Liquimag B; Calcined magnesia; Caustic magnesite; Maglite D; Maglite K; Maglite S; Maglite Y; Magnesia monoxide; Anscor P; Hamag LP; Magox OP; FloMag HP; Fert-O-Mag; Kyowamag 20; Kyowamag 30; Kyowamag 40; Kyowamag 60; Elastomag 100; Elastomag 170; FloMag HP-ER; Kyowamag 100; Kyowamag 150; Kyowamag 150B; Kyowaway 150; Kyowaad 100; Luvatol MK 35; Magchem 100; Magox 85; Magox 90; Magox 95; Magox 98; Mag Chem 10; Mag Chem 35; Heavy calcined magnesia; Mag Chem 200AD; KM 3 (oxide); KMACH-F; Mag Chem 200D; FMR-PC; Magnesium oxide, p.a., 95.0%; HP 10 (oxide); Magmilax bolus; Magnezu tlenek; 100A (oxide); Magnezu tlenek [Polish]; Mag Chem 10-40; AM 2 (cement additive); Mag Chem 10-200; Mag Chem 10-325; Magnesium oxide substrate, 10x10x0.5mm, polished one side, 100 orientation; Magnesium oxide substrate, 10x10x0.5mm, polished one side, 110 orientation; Periclase (MgO); CCRIS 3659; Magnesium oxide, fume; HSDB 1652; SLO 369; SLO 469; KM 40; EINECS 215-171-9; KMB 100-200; Magnesium oxide [USP:JAN]; Magnesii oxidum; Maox; Magnesia oxydata; Calcined magnesite; MgO Nanoparticles; Mag-Ox; Magnesium oxide (fume), Inhalable; Magmitt (TN); Light magnesium oxide; Magnesium oxide heavy; Magnesium oxide, CP; Magnesium (as oxide); Magnesium oxide, light; Magnesium oxide (fume); Magnesium oxide, 97%; Magnesium Oxide nanowire; Magnesium Oxide DC USP; Magnesium Oxide Dispersion; Magnesium Oxide Nanopowder; Magnesium oxide ACS Reagent; Magnesium Oxide DC Granular; Nano Magnesium Oxide Powder; Magnesium Oxide Light, USP; Magnesium oxide, Respirable dust and fume, as Mg; Magnesium oxide (JP17/USP); Magnesium oxide, light, 95%; Active Magnesium Oxide RA 40; INS NO.530; CHEMBL1200572; DTXSID9049665; Active Magnesium Oxide RA 110; Active Magnesium Oxide RA 150; INS-530; Magnesium Oxide-Technical Grade KP; Light Active Magnesium Oxide RA 70; Magnesium Oxide Powder, 99% Nano; Magnesium oxide, ACS reagent, 97%; NSC761263; Magnesium Oxide Powder,>= 99% Nano; NSC-761263; Pharmaceutical Grade Magnesium Oxide HA4; E530; Magnesium Oxide (MgO) Sputtering Targets; Magnesium Oxide Single Crystal Substrates; Magnesium oxide, -10-+50 mesh, 98%; Magnesium oxide, Vetec(TM) reagent grade; Magnesium Oxide Nanoparticles / Nanopowder; Magnesium oxide, 99.995% (metals basis); E-530; FT-0628095; Magnesium Oxide Special Industrial Grade SIG; Magnesium oxide, 99.99% trace metals basis; Active Pharmaceutical Magnesium Oxide PHRA50; Magnesium Oxide Reactive Technical Grade KPLL; Magnesium oxide, SAJ first grade, >=96.0%; Magnesium oxide, SAJ first grade, >=98.0%; D01167; Magnesium oxide, >=99.99% trace metals basis; Magnesium oxide, 2 part ceramic adhesive paste; Magnesium oxide, SAJ special grade, >=99.0%; Pharmaceutical Magnesium Oxide Grade HA and HA5; Magnesium oxide, >26% in a non hazardous diluent; Magnesium oxide, fused, 150-325 mesh, >=95%; Q214769; Magnesium oxide, tested according to Ph.Eur., heavy; Magnesium oxide, >=99% trace metals basis, -325 mesh; Magnesium oxide, nanopowder, <50 nm particle size (BET); Magnesium oxide, BioUltra, >=97.0% (calcined substance, KT); Magnesia sticks, for pearl-tests, package of 100 magnesia sticks; Magnesia sticks, for pearl-tests, package of 25 magnesia sticks; Magnesium oxide, fused, chips, -4 mesh, 99.9% trace metals basis; Magnesium oxide substrate, 10x10x0.5mm, polished one side, 111 orientation; Magnesium oxide substrate, 10x10x1mm, polished one side, 100 orientation; Magnesium oxide substrate, 10x10x1mm, polished one side, 110 orientation; Magnesium oxide substrate, 10x10x1mm, polished two sides, 100 orientation; Magnesium oxide, puriss. p.a., >=98.0% (based on calcined substance, KT); Magnesium oxide, purum, >=97.0% (based on calcined substance, KT), light; Magnesia Rectangular Plate,Length (mm), 105,Width (mm), 50,Thickness (mm), 10; Magnesia Rectangular Plate,Length (mm), 145,Width (mm), 70,Thickness (mm), 15; Magnesium oxide Crucible, Cylindrical, Flat Base, HtxOD (mm), 37x20, Vol (ml), 5; Magnesium oxide Crucible, Cylindrical, Flat Base, HtxOD (mm), 43x24, Vol (ml), 10; Magnesium oxide Crucible, Cylindrical, Flat Base, HtxOD (mm), 90x45, Vol (ml), 100; Magnesium Oxide Crucible, Cylindrical, Flat Base,OD (mm), 25,Height (mm), 25; Magnesium Oxide Crucible, Cylindrical, Flat Base,OD (mm), 32,Height (mm), 32; Magnesium Oxide Crucible, Cylindrical, Flat Base,OD (mm), 44,Height (mm), 44; Magnesium Oxide Crucible, Cylindrical, Flat Base,OD (mm), 76,Height (mm), 76; Magnesium Oxide Rectangular Tray,Length (mm), 100,Width (mm), 100,Height (mm), 25.4; Magnesium Oxide Rectangular Tray,Length (mm), 100,Width (mm), 25,Height (mm), 12.7; Magnesium Oxide Rectangular Tray,Length (mm), 100,Width (mm), 50,Height (mm), 12.7; Magnesium Oxide Rectangular Tray,Length (mm), 150,Width (mm), 100,Height (mm), 25.4; Magnesium Oxide Rectangular Tray,Length (mm), 150,Width (mm), 75,Height (mm), 25.4; Magnesium Oxide Rectangular Tray,Length (mm), 50,Width (mm), 50,Height (mm), 12.7; Magnesium Oxide Rectangular Tray,Length (mm), 75,Width (mm), 75,Height (mm), 25.4; Magnesium oxide sputtering target, 50.8mm (2.0in) dia x 3.18mm (0.125in) thick; Magnesium oxide sputtering target, 50.8mm (2.0in) dia x 6.35mm (0.250in) thick; Magnesium oxide sputtering target, 76.2mm (3.0in) dia x 3.18mm (0.125in) thick; Magnesium oxide sputtering target, 76.2mm (3.0in) dia x 6.35mm (0.250in) thick; Magnesium oxide substrate, 10x10x0.5mm, polished two sides, 100 orientation; Magnesium oxide, puriss. p.a., ACS reagent, >=97% (calcined substance, KT); Magnesium oxide, (single crystal substrate), <111>, >=99.9% trace metals basis, L x W x thickness 10 mm x 10 mm x 0.5 mm; Magnesium oxide, (single crystal substrate), >=99.9% trace metals basis, <100>, L x W x thickness 10 mm x 10 mm x 0.5 mm; Magnesium oxide, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E 530, light, 98.0-100.5% (calc. for dried substance) Click to Show/Hide
Therapeutic Class	Minerals And Electrolytes
Structure
Structure	3D Structure		2D Structure
Formula	MgO
InChI	InChI=1S/Mg.O
InChIKey	CPLXHLVBOLITMK-UHFFFAOYSA-N
Canonical SMILES	O=[Mg]
External Link
External Link	Pubchem ID	14792

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM001 Altered gastrointestinal dynamics BM003 Complex formation BM004 Adsorption BM005 Altered gastric pH BM009 Altered absorption (Unspecific) BM029 Altered urine pH BM059 Increased risk of hypermagnesemia BM107 Attenuated pharmacological effects (Unspecific)
Relation Graph

Full list of drugs interacting with Magnesium oxide
Affected gastrointestinal absorption
	Altered gastrointestinal dynamics					Drug Num: 14
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0045		Alprazolam	C17H13ClN4	2118	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0317		Chlordiazepoxide	C16H14ClN3O	2712	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0356		Clobazam	C16H13ClN2O2	2789	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0362		Clonazepam	C15H10ClN3O3	2802	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0473		Diazepam	C16H13ClN2O	3016	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0604		Estazolam	C16H11ClN4	3261	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0679		Flurazepam	C21H23ClFN3O	3393	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0748		Halazepam	C17H12ClF3N2O	31640	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D0951		Lorazepam	C15H10Cl2N2O2	3958	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D1367		Quazepam	C17H11ClF4N2S	4999	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D1060		Midazolam	C18H13ClFN3	4192	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D1197		Oxazepam	C15H11ClN2O2	4616	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D1547		Temazepam	C16H13ClN2O2	5391	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
D1632		Triazolam	C17H12Cl2N4	5556	Minor		Inter Info	[171], [172], [173], [174], [175], [176], [177], [178], [179]
	Complex formation					Drug Num: 62
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0181		Bictegravir	C21H18F3N3O5	90311989	Major		Inter Info	[1], [2], [3]
D0515		Dolutegravir	C20H19F2N3O5	54726191	Major		Inter Info	[4]
D1231		Patiromer	NA	NA	Major		Inter Info	[6], [7], [8]
D1605		Tolevamer	C11H16O3S	58817179	Major		Inter Info	[6], [7], [8]
D0277		Cefdinir	C14H13N5O5S2	6915944	Moderate		Inter Info	[30]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[1], [2], [36], [37], [38], [39], [40], [41]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[17], [36], [75], [76], [77], [78], [79], [80], [81], [82], [62], [83], [72]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[17], [36], [75], [76], [77], [78], [79], [80], [81], [82], [62], [83], [72]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0623		Etidronic acid	C2H8O7P2	3305	Moderate		Inter Info	[86], [87], [88]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0783		Ibandronate	C9H23NO7P2	60852	Moderate		Inter Info	[89], [90], [91], [86], [92], [88]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[102], [103], [1], [2], [104], [105], [106], [107], [108], [109], [110]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[102], [103], [1], [2], [104], [105], [106], [107], [108], [109], [110]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0144		Baloxavir marboxil	C27H23F2N3O7S	124081896	Moderate		Inter Info	[112]
D0433		Deferiprone	C7H9NO2	2972	Moderate		Inter Info	[122]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0561		Eltrombopag	C25H22N4O4	135449332	Moderate		Inter Info	[2], [123]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[1], [2], [36], [37], [38], [39], [40], [41]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Moderate		Inter Info	[102], [103], [1], [2], [104], [105], [106], [107], [108], [109], [110]
D1175		Omadacycline	C29H40N4O7	54697325	Moderate		Inter Info	[17], [36], [75], [76], [77], [78], [79], [80], [81], [82], [62], [83], [72]
D1377		Raltegravir	C20H21FN6O5	54671008	Moderate		Inter Info	[103], [1], [2], [139], [140], [141]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[17], [36], [75], [76], [77], [78], [79], [80], [81], [82], [62], [83], [72]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[106], [107], [108]
D1635		Triethylenetetramine	C6H18N4	5565	Moderate		Inter Info	[144]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[17], [36], [75], [76], [77], [78], [79], [80], [81], [82], [62], [83], [72]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[150]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1209		Oxytetracycline	C22H24N2O9	54675779	Moderate		Inter Info	[17], [36], [75], [76], [77], [78], [79], [80], [81], [82], [62], [83], [72]
D1245		Penicillamine	C5H11NO2S	5852	Moderate		Inter Info	[151], [152], [153], [154], [155], [156], [157], [62]
D1412		Risedronic acid	C7H11NO7P2	5245	Moderate		Inter Info	[91], [86], [88]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[17], [36], [75], [76], [77], [78], [79], [80], [81], [82], [62], [83], [72]
D1584		Tiludronic acid	C7H9ClO6P2S	60937	Moderate		Inter Info	[86], [87], [88]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[42], [43], [44], [45], [46], [47], [32], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72]
D0010		Acebutolol	C18H28N2O4	1978	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D0117		Atenolol	C14H22N2O3	2249	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D0173		Betaxolol	C18H29NO3	2369	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D0188		Bisoprolol	C18H31NO4	2405	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D0265		Carteolol	C16H24N2O3	2583	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D0267		Carvedilol	C24H26N2O4	2585	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D0491		Digoxin	C41H64O14	2724385	Minor		Inter Info	[196], [197], [198], [36], [199], [200], [62], [201], [202]
D0705		Gabapentin	C9H17NO2	3446	Minor		Inter Info	[204]
D0884		Labetalol	C19H24N2O3	3869	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D0490		Digitoxin	C41H64O13	441207	Minor		Inter Info	[196], [197], [198], [36], [199], [200], [62], [201], [202]
D1114		Nebivolol	C22H25F2NO4	71301	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D1049		Metoprolol	C15H25NO3	4171	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D1098		Nadolol	C17H27NO4	39147	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Minor		Inter Info	[215]
D1244		Penbutolol	C18H29NO2	37464	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D1293		Pindolol	C14H20N2O2	4828	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D1357		Propranolol	C16H21NO2	4946	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D1498		Sotalol	C12H20N2O3S	5253	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
D1585		Timolol	C13H24N4O3S	33624	Minor		Inter Info	[36], [163], [164], [165], [166], [167], [168]
	Adsorption					Drug Num: 15
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0037		Alimemazine	C18H22N2S	5574	Minor		Inter Info	[17], [169], [170]
D0324		Chlorpromazine	C17H19ClN2S	2726	Minor		Inter Info	[17], [169], [184], [185], [170]
D0678		Fluphenazine	C22H26F3N3OS	3372	Minor		Inter Info	[17], [169], [184], [185], [170]
D1026		Methotrimeprazine	C19H24N2OS	72287	Minor		Inter Info	[17], [169], [184], [185], [170]
D1010		Mesoridazine	C21H26N2OS2	4078	Minor		Inter Info	[17], [169], [184], [185], [170]
D1019		Methdilazine	C18H20N2S	14677	Minor		Inter Info	[17], [169], [184], [185], [170]
D1257		Perphenazine	C21H26ClN3OS	4748	Minor		Inter Info	[17], [169], [184], [185], [170]
D1346		Prochlorperazine	C20H24ClN3S	4917	Minor		Inter Info	[17], [169], [184], [185], [170]
D1351		Promazine	C17H20N2S	4926	Minor		Inter Info	[17], [169], [184], [185], [170]
D1352		Promethazine	C17H20N2S	4927	Minor		Inter Info	[17], [169], [184], [185], [170]
D1355		Propiomazine	C20H24N2OS	4940	Minor		Inter Info	[17], [169], [184], [185], [170]
D1572		Thiethylperazine	C22H29N3S2	5440	Minor		Inter Info	[17], [169], [184], [185], [170]
D1574		Thioridazine	C21H26N2S2	5452	Minor		Inter Info	[17], [169], [184], [185], [170]
D1637		Trifluoperazine	C21H24F3N3S	5566	Minor		Inter Info	[17], [169], [184], [185], [170]
D1638		Triflupromazine	C18H19F3N2S	5568	Minor		Inter Info	[17], [169], [184], [185], [170]
	Altered gastric pH					Drug Num: 70
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1459		Selpercatinib	C29H31N7O3	134436906	Major		Inter Info	[9]
D0013		Acetohexamide	C15H20N2O4S	1989	Moderate		Inter Info	[10], [11], [12], [13], [14], [15], [16]
D0074		Amphetamine	C9H13N	3007	Moderate		Inter Info	[20]
D0080		Amprenavir	C25H35N3O6S	65016	Moderate		Inter Info	[21], [22]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[23], [24], [25]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[20]
D0278		Cefditoren	C19H18N6O5S3	9870843	Moderate		Inter Info	[31]
D0297		Cefuroxime	C16H16N4O8S	5479529	Moderate		Inter Info	[32], [33], [34], [35]
D0325		Chlorpropamide	C10H13ClN2O3S	2727	Moderate		Inter Info	[10], [11], [12], [13], [14], [15], [16]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[73]
D0595		Erlotinib	C22H23N3O4	176870	Moderate		Inter Info	[1], [2], [84], [85]
D0727		Glimepiride	C24H34N4O5S	3476	Moderate		Inter Info	[10], [11], [12], [13], [14], [15], [16]
D0728		Glipizide	C21H27N5O4S	3478	Moderate		Inter Info	[10], [11], [12], [13], [14], [15], [16]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[10], [11], [12], [13], [14], [15], [16]
D0867		Itraconazole	C35H38Cl2N8O4	55283	Moderate		Inter Info	[93], [94], [95], [96], [97]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Moderate		Inter Info	[93], [94], [98], [99], [2], [100], [101], [97]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[20]
D0008		Acalabrutinib	C26H23N7O2	71226662	Moderate		Inter Info	[111]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[32], [35]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[2], [113]
D0229		Cabotegravir	C19H17F2N3O5	54713659	Moderate		Inter Info	[1], [99], [114], [115]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[116]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[1], [2], [117], [118], [119], [120], [121]
D0465		Dextroamphetamine	C9H13N	5826	Moderate		Inter Info	[20]
D0898		Ledipasvir	C49H54F2N8O6	67505836	Moderate		Inter Info	[124]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[125], [20], [126]
D1124		Neratinib	C30H29ClN6O3	9915743	Moderate		Inter Info	[132]
D1136		Nilotinib	C28H22F3N7O	644241	Moderate		Inter Info	[1], [2]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[2], [133], [134], [135], [136], [137]
D1258		Pexidartinib	C20H15ClF3N5	25151352	Moderate		Inter Info	[138]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[142]
D1408		Riociguat	C20H19FN8O2	11304743	Moderate		Inter Info	[143]
D1686		Velpatasvir	C49H54N8O8	67683363	Moderate		Inter Info	[145]
D1094		Mycophenolate mofetil	C23H31NO7	5281078	Moderate		Inter Info	[146], [147], [148], [149]
D1095		Mycophenolic acid	C17H20O6	446541	Moderate		Inter Info	[146], [147], [148], [149]
D1430		Rosuvastatin	C22H28FN3O6S	446157	Moderate		Inter Info	[161]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Moderate		Inter Info	[162], [25]
D1601		Tolazamide	C14H21N3O3S	5503	Moderate		Inter Info	[10], [11], [12], [13], [14], [15], [16]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[10], [11], [12], [13], [14], [15], [16]
D0156		Benazepril	C24H28N2O5	5362124	Minor		Inter Info	[180]
D0172		Betamethasone	C22H29FO5	9782	Minor		Inter Info	[181], [182], [183]
D0254		Captopril	C9H15NO3S	44093	Minor		Inter Info	[180]
D0337		Cimetidine	C10H16N6S	2756	Minor		Inter Info	[186], [181], [187], [188], [189], [17], [190], [191], [192], [193], [194], [195]
D0453		Dexamethasone	C22H29FO5	5743	Minor		Inter Info	[181], [182], [183]
D0539		Duloxetine	C18H19NOS	60835	Minor		Inter Info	[203]
D0567		Enalapril	C20H28N2O5	5388962	Minor		Inter Info	[180]
D0636		Famotidine	C8H15N7O2S3	5702160	Minor		Inter Info	[186], [181], [187], [188], [189], [17], [190], [191], [192], [193], [194], [195]
D0671		Fludrocortisone	C21H29FO5	31378	Minor		Inter Info	[181], [182], [183]
D0695		Fosinopril	C30H46NO7P	55891	Minor		Inter Info	[180]
D0773		Hydrocortisone	C21H30O5	5754	Minor		Inter Info	[181], [182], [183]
D0918		Levodopa	C9H11NO4	6047	Minor		Inter Info	[205], [206], [207], [208]
D0938		Lisinopril	C21H31N3O5	5362119	Minor		Inter Info	[180]
D0133		Axitinib	C22H18N4OS	6450551	Minor		Inter Info	[209]
D1313		Ponatinib	C29H27F3N6O	24826799	Minor		Inter Info	[1], [210]
D1701		Vismodegib	C19H14Cl2N2O3S	24776445	Minor		Inter Info	[1], [2], [211]
D0991		Mefenamic acid	C15H15NO2	4044	Minor		Inter Info	[212]
D1041		Methylprednisolone	C22H30O5	6741	Minor		Inter Info	[181], [182], [183]
D1082		Moexipril	C27H34N2O7	91270	Minor		Inter Info	[180]
D1109		Naproxen	C14H14O3	156391	Minor		Inter Info	[213], [214]
D1151		Nizatidine	C12H21N5O2S2	3033637	Minor		Inter Info	[186], [181], [187], [188], [189], [17], [190], [191], [192], [193], [194], [195]
D1256		Perindopril	C19H32N2O5	107807	Minor		Inter Info	[180]
D1332		Prednisolone	C21H28O5	5755	Minor		Inter Info	[181], [182], [183]
D1334		Prednisone	C21H26O5	5865	Minor		Inter Info	[181], [182], [183]
D1369		Quinapril	C25H30N2O5	54892	Minor		Inter Info	[180]
D1379		Ramipril	C23H32N2O5	5362129	Minor		Inter Info	[180]
D1381		Ranitidine	C13H22N4O3S	3001055	Minor		Inter Info	[186], [181], [187], [188], [189], [17], [190], [191], [192], [193], [194], [195]
D1382		Ranitidine (bismuth citrate)	C13H22N4O3S	3001055	Minor		Inter Info	[186], [188], [17]
D1581		Ticlopidine	C14H14ClNS	5472	Minor		Inter Info	[216]
D1618		Trandolapril	C24H34N2O5	5484727	Minor		Inter Info	[180]
D1628		Triamcinolone	C21H27FO6	31307	Minor		Inter Info	[181], [182], [183]
	Altered absorption (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0439		Delavirdine	C22H28N6O3S	5625	Moderate		Inter Info	[74]
Affected excretion pathways
	Altered urine pH					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[17], [18], [19]
D0331		Choline salicylate	C12H19NO4	54686350	Moderate		Inter Info	[17], [18], [19]
D1020		Methenamine	C6H12N4	4101	Moderate		Inter Info	[127], [128], [129], [130], [131]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[17], [18], [19]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[158], [159], [160]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[17], [18], [19]
Pharmacodynamic additive effects
	Increased risk of hypermagnesemia					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0233		Calcifediol	C27H44O2	5283731	Moderate		Inter Info	[26], [27], [28], [29]
D0234		Calcitriol	C27H44O3	5280453	Moderate		Inter Info	[26], [27], [28], [29]
D0328		Cholecalciferol	C27H44O	5280795	Moderate		Inter Info	[26], [27], [28], [29]
D0495		Dihydrotachysterol	C28H46O	5311071	Moderate		Inter Info	[26], [27], [28], [29]
D0591		Ergocalciferol	C28H44O	5280793	Moderate		Inter Info	[26], [27], [28], [29]
D0527		Doxercalciferol	C28H44O2	5281107	Moderate		Inter Info	[26], [27], [28], [29]
D0968		Magnesium carbonate	CMgO3	11029	Moderate		Inter Info	[2]
D0969		Magnesium chloride	Cl2H12MgO6	643991	Moderate		Inter Info	[2]
D0973		Magnesium hydroxide	H2MgO2	14791	Moderate		Inter Info	[2]
D0975		Magnesium sulfate	MgO4S	24083	Moderate		Inter Info	[2]
D1226		Paricalcitol	C27H44O3	5281104	Moderate		Inter Info	[26], [27], [28], [29]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0590		Erdafitinib	C25H30N6O2	67462786	Major		Inter Info	[5]

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118	Product Information. Dexilant (dexlansoprazole). Takeda Pharmaceuticals America, Lincolnshire, IL.
119	Product Information. Prevacid (lansoprazole). TAP Pharmaceuticals Inc, Deerfield, IL.
120	Product Information. Tafinlar (dabrafenib). GlaxoSmithKline, Research Triangle Park, NC.
121	Product Information. Zantac (ranitidine). Glaxo Wellcome, Research Triangle Park, NC.
122	Product Information. Ferriprox (deferiprone). ApoPharma USA Inc, Rockville, MD.
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130	Product Information. Hyophen (benzoic acid/hyoscy/methen/mblue/phenylsal). BioComp Pharma, San Antonio, TX.
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142	Product Information. Edurant (rilpivirine). Tibotec Pharmaceuticals, Titusville, NJ.
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144	Product Information. Syprine (trientine). Aton Pharma, Lawrenceville, NJ.
145	Product Information. Epclusa (sofosbuvir-velpatasvir). Gilead Sciences, Foster City, CA.
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149	Product Information. Myfortic (mycophenolic acid). Novartis Pharmaceuticals, East Hanover, NJ.
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157	Product Information. Cuprimine (penicillamine). Merck & Co, Inc, West Point, PA.
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203	Product Information. Cymbalta (duloxetine). Lilly, Eli and Company, Indianapolis, IN.
204	Product Information. Neurontin (gabapentin). Parke-Davis, Morris Plains, NJ.
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209	Product Information. Inlyta (axitinib). Pfizer U.S. Pharmaceuticals Group, New York, NY.
210	Product Information. Iclusig (ponatinib). Ariad Pharmaceuticals Inc, Cambridge, MA.
211	Product Information. Erivedge (vismodegib). Genentech, South San Francisco, CA.
212	Neuvonen PJ, Kivisto KT "Effect of magnesium hydroxide on the absorption of tolfenamic and mefenamic acids." Eur J Clin Pharmacol 35 (1988): 495-501. [PMID: 3266151]
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216	Product Information. Ticlid (ticlopidine). Syntex Laboratories Inc, Palo Alto, CA.

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