Drug General Information (ID: DDIQIFPUB0)
Drug Name			Gabapentin		Drug Info		Magnesium oxide		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Analgesics				Minerals And Electrolytes
Structure

Mechanism of Gabapentin-Magnesium oxide Interaction (Severity Level: Minor)
Complex formation Click to Show/Hide Mechanism Graph
Drug Name		Gabapentin				Magnesium oxide
Mechanism		Binds to polyvalent cations				Polyvalent cations
Key Mechanism Factor 1
		Factor Name		Chelation
		Factor Description		Chelation is a direct drug interaction that usually involves the formation of dimers or trimers, resulting in larger complexes and poorer absorption.
Mechanism Description		Decreased absorption of Magnesium oxide due to formation of complexes caused by Gabapentin

References
1	Product Information. Neurontin (gabapentin). Parke-Davis, Morris Plains, NJ.