Drug General Information (ID: DDIYUK8Z4W)
Drug Name			Ticlopidine		Drug Info		Magnesium oxide		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Fibrinolytic Agents				Minerals And Electrolytes
Structure

Mechanism of Ticlopidine-Magnesium oxide Interaction (Severity Level: Minor)
Altered gastric pH Click to Show/Hide Mechanism Graph
Drug Name		Ticlopidine				Magnesium oxide
Mechanism		Gastric pH sensitive				Gastric alkalinizer
Key Mechanism Factor 1
		Factor Name		Gastric pH
		Factor Description		The normal pH range of gastric acid is between 1.5 and 3.5 and is highly acidic, consisting mainly of hydrochloric acid. Changes in the pH of the stomach can alter the absorption of drugs.
Mechanism Description		Decreased absorption of Ticlopidine due to altered gastric pH caused by Magnesium oxide

References
1	Product Information. Ticlid (ticlopidine). Syntex Laboratories Inc, Palo Alto, CA.