Drug General Information (ID: D1581)
  Drug Name
Ticlopidine
  Drug Type Small molecule
  Drug Synonymous
Ticlid; Ticlopidina; Ticlopidinum; PCR 5332; Ticlid (TN); Ticlopidin-Puren; Ticlopidina [INN-Spanish]; Ticlopidine (INN); Ticlopidine [INN:BAN]; Ticlopidinum [INN-Latin]; Ticlopidin-Puren (TN); 5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine; 5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
    Click to Show/Hide
  Disease Class 8B20: Ischaemic/haemorrhagic stroke
  Therapeutic Class Fibrinolytic Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C14H14ClNS
  InChI 1S/C14H14ClNS/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14/h1-4,6,8H,5,7,9-10H2
  InChIKey PHWBOXQYWZNQIN-UHFFFAOYSA-N
  Canonical SMILES C1CN(CC2=C1SC=C2)CC3=CC=CC=C3Cl
  External Link
Pubchem ID 5472
CAS Number 55142-85-3
CHEBI ID 9588
TTD ID D05LBU
INTEDE ID DR1592
VARIDT ID DR00842

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
AM004  Affected intra/extra-hepatic metabolism
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM005  Altered gastric pH
BM017  CYP450 enzyme inhibition
BM050  Increased risk of bleeding
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Ticlopidine
      Affected gastrointestinal absorption
   Altered gastric pH Drug Num:  7
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0049
 
Aluminum hydroxide
 
AlH3O3
 
10176082 
Minor    Inter Info   
[91]
D0236
 
Calcium carbonate
 
CCaO3
 
10112 
Minor    Inter Info   
[91]
D0967
 
Magaldrate
 
AlHMgO5S+2
 
3086011 
Minor    Inter Info   
[91]
D0968
 
Magnesium carbonate
 
CMgO3
 
11029 
Minor    Inter Info   
[91]
D0973
 
Magnesium hydroxide
 
H2MgO2
 
14791 
Minor    Inter Info   
[91]
D0974
 
Magnesium oxide
 
MgO
 
14792 
Minor    Inter Info   
[91]
D1480
 
Sodium bicarbonate
 
CHNaO3
 
516892 
Minor    Inter Info   
[91]
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  43
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0336
 
Cilostazol
 
C20H27N5O2
 
2754 
Major    Inter Info   
[11], [23], [24], [25]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Major    Inter Info   
[26], [27], [28]
D0364
 
Clopidogrel
 
C16H16ClNO2S
 
60606 
Major    Inter Info   
[29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44]
D1385
 
Rasagiline
 
C12H13N
 
3052776 
Major    Inter Info   
[21], [11], [65]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Major    Inter Info   
[69], [70], [71]
D1596
 
Tizanidine
 
C9H8ClN5S
 
5487 
Major    Inter Info   
[73], [74], [75], [76], [77], [78], [79], [80]
D0308
 
Cevimeline
 
C10H17NOS
 
83898 
Moderate    Inter Info   
[95]
D0043
 
Alosetron
 
C17H18N4O
 
2099 
Moderate    Inter Info   
[146]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Moderate    Inter Info   
[147]
D0105
 
Aripiprazole
 
C23H27Cl2N3O2
 
60795 
Moderate    Inter Info   
[150]
D0112
 
Asenapine
 
C17H16ClNO
 
3036780 
Moderate    Inter Info   
[151]
D0119
 
Atomoxetine
 
C17H21NO
 
54841 
Moderate    Inter Info   
[152], [153], [154]
D0157
 
Bendamustine
 
C16H21Cl2N3O2
 
65628 
Moderate    Inter Info   
[155]
D0220
 
Bupropion
 
C13H18ClNO
 
444 
Moderate    Inter Info   
[21], [57], [11], [159], [160], [161], [162], [163], [164], [165], [166], [167]
D0356
 
Clobazam
 
C16H13ClN2O2
 
2789 
Moderate    Inter Info   
[169]
D0379
 
Codeine
 
C18H21NO3
 
5284371 
Moderate    Inter Info   
[170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182]
D0424
 
Darifenacin
 
C28H30N2O2
 
444031 
Moderate    Inter Info   
[183], [153]
D0466
 
Dextromethorphan
 
C18H25NO
 
5360696 
Moderate    Inter Info   
[21], [11], [185], [61], [153], [186]
D0562
 
Eluxadoline
 
C32H35N5O5
 
11250029 
Moderate    Inter Info   
[187]
D0621
 
Ethotoin
 
C11H12N2O2
 
3292 
Moderate    Inter Info   
[202], [203], [204]
D0628
 
Etravirine
 
C20H15BrN6O
 
193962 
Moderate    Inter Info   
[205]
D0638
 
Fedratinib
 
C27H36N6O3S
 
16722836 
Moderate    Inter Info   
[11], [206]
D0655
 
Fesoterodine
 
C26H37NO3
 
6918558 
Moderate    Inter Info   
[207]
D0665
 
Flibanserin
 
C20H21F3N4O
 
6918248 
Moderate    Inter Info   
[208]
D0697
 
Fosphenytoin
 
C16H15N2O6P
 
56339 
Moderate    Inter Info   
[209], [210], [211], [202], [203], [212], [213], [91], [214], [204]
D0916
 
Levobupivacaine
 
C18H28N2O
 
92253 
Moderate    Inter Info   
[11], [247]
D1143
 
Nitisinone
 
C14H10F3NO5
 
115355 
Moderate    Inter Info   
[191], [21], [11]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Moderate    Inter Info   
[209], [210], [211], [202], [203], [212], [213], [91], [214], [204]
D1292
 
Pimozide
 
C28H29F2N3O
 
16362 
Moderate    Inter Info   
[252], [253]
D1299
 
Pirfenidone
 
C12H11NO
 
40632 
Moderate    Inter Info   
[11], [254]
D1302
 
Pitolisant
 
C17H26ClNO
 
9948102 
Moderate    Inter Info   
[11], [176], [255]
D1378
 
Ramelteon
 
C16H21NO2
 
208902 
Moderate    Inter Info   
[256]
D1422
 
Roflumilast
 
C17H14Cl2F2N2O3
 
449193 
Moderate    Inter Info   
[11], [257], [258]
D1427
 
Ropinirole
 
C16H24N2O
 
5095 
Moderate    Inter Info   
[259], [260]
D1505
 
Stiripentol
 
C14H18O3
 
5311454 
Moderate    Inter Info   
[11], [66], [264]
D1536
 
Tasimelteon
 
C15H19NO2
 
10220503 
Moderate    Inter Info   
[265]
D1586
 
Timolol (ophthalmic)
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[267], [268], [269]
D0208
 
Brivaracetam
 
C11H20N2O2
 
9837243 
Minor    Inter Info   
[11], [287]
D0248
 
Cannabidiol
 
C21H30O2
 
644019 
Minor    Inter Info   
[11], [288]
D0516
 
Donepezil
 
C24H29NO3
 
3152 
Minor    Inter Info   
[293], [176], [294], [295]
D1265
 
Phenobarbital
 
C12H12N2O3
 
4763 
Minor    Inter Info   
[296]
D1383
 
Ranolazine
 
C24H33N3O4
 
56959 
Minor    Inter Info   
[297]
D1607
 
Tolterodine
 
C22H31NO
 
443879 
Minor    Inter Info   
[298], [299], [176]
      Pharmacodynamic additive effects
   Increased risk of bleeding Drug Num:  123
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0005
 
Abciximab
 
NA
 
NA
Major    Inter Info   
[1], [2], [3], [4]
D0537
 
Drotrecogin alfa
 
NA
 
NA
Major    Inter Info   
[5]
D0588
 
Eptifibatide
 
C35H49N11O9S2
 
448812 
Major    Inter Info   
[1], [2], [3], [4]
D0784
 
Ibritumomab tiuxetan
 
NA
 
NA
Major    Inter Info   
[6]
D0904
 
Lepirudin
 
C287H440N80O111S6
 
118856773 
Major    Inter Info   
[7], [8], [9]
D0008
 
Acalabrutinib
 
C26H23N7O2
 
71226662 
Major    Inter Info   
[10]
D0096
 
Apixaban
 
C25H25N5O4
 
10182969 
Major    Inter Info   
[11], [12]
D0102
 
Ardeparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[13], [14], [15]
D0104
 
Argatroban
 
C23H36N6O5S
 
92722 
Major    Inter Info   
[7], [8], [9]
D0129
 
Avapritinib
 
C26H27FN10
 
118023034 
Major    Inter Info   
[11], [16]
D0176
 
Betrixaban
 
C23H22ClN5O3
 
10275777 
Major    Inter Info   
[17], [18]
D0230
 
Cabozantinib
 
C28H24FN3O5
 
25102847 
Major    Inter Info   
[19]
D0247
 
Cangrelor
 
C17H25Cl2F3N5O12P3S2
 
9854012 
Major    Inter Info   
[17], [11], [20]
D0250
 
Caplacizumab
 
NA
 
NA
Major    Inter Info   
[21], [11], [22]
D0414
 
Dalteparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[45], [46], [13], [47], [14], [15], [48]
D0415
 
Danaparoid
 
NA
 
NA
Major    Inter Info   
[13], [14], [15]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Major    Inter Info   
[49]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Major    Inter Info   
[50], [51]
D0435
 
Defibrotide
 
C20H21N4O6P
 
135565962 
Major    Inter Info   
[11], [52]
D0447
 
Desirudin
 
C287H440N80O110S6
 
16129703 
Major    Inter Info   
[53], [54]
D0551
 
Edoxaban
 
C24H30ClN7O4S
 
10280735 
Major    Inter Info   
[55]
D0574
 
Enoxaparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[45], [46], [13], [47], [14], [15], [48]
D0690
 
Fondaparinux
 
C31H53N3O49S8
 
5282448 
Major    Inter Info   
[45], [46], [13], [47], [14], [15], [48]
D0785
 
Ibrutinib
 
C25H24N6O2
 
24821094 
Major    Inter Info   
[56], [57], [11], [58]
D0805
 
Inotersen
 
C230H318N69O121P19S19
 
121492004 
Major    Inter Info   
[11], [50], [59]
D1174
 
Omacetaxine mepesuccinate
 
C29H39NO9
 
285033 
Major    Inter Info   
[50], [60]
D1221
 
Panobinostat
 
C21H23N3O2
 
6918837 
Major    Inter Info   
[21], [11], [61]
D1313
 
Ponatinib
 
C29H27F3N6O
 
24826799 
Major    Inter Info   
[62]
D1328
 
Prasugrel
 
C20H20FNO3S
 
6918456 
Major    Inter Info   
[11], [63]
D1380
 
Ramucirumab
 
NA
 
NA
Major    Inter Info   
[64]
D1387
 
Regorafenib
 
C21H15ClF4N4O3
 
11167602 
Major    Inter Info   
[11], [66], [67]
D1417
 
Rivaroxaban
 
C19H18ClN3O5S
 
9875401 
Major    Inter Info   
[68]
D1588
 
Tinzaparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[13], [14], [15]
D1592
 
Tipranavir
 
C31H33F3N2O5S
 
54682461 
Major    Inter Info   
[72]
D1593
 
Tirofiban
 
C22H36N2O5S
 
60947 
Major    Inter Info   
[1], [2], [3], [4]
D1623
 
Trastuzumab emtansine
 
NA
 
NA
Major    Inter Info   
[21], [11], [81]
D1705
 
Vorapaxar
 
C29H33FN2O4
 
10077130 
Major    Inter Info   
[82]
D1718
 
Zanubrutinib
 
C27H29N5O3
 
135565884 
Major    Inter Info   
[50]
D1613
 
Tositumomab
 
NA
 
NA
Major    Inter Info   
[83], [84]
D1614
 
Tositumomab (I-131)
 
NA
 
NA
Major    Inter Info   
[83], [84]
D0047
 
Alteplase
 
NA
 
NA
Moderate    Inter Info   
[85], [86], [87], [88], [89], [90], [91], [92]
D0088
 
Anistreplase
 
NA
 
NA
Moderate    Inter Info   
[85], [87], [92]
D0114
 
Asparaginase Escherichia coli
 
NA
 
NA
Moderate    Inter Info   
[93], [11], [94]
D0189
 
Bivalirudin
 
C98H138N24O33
 
16129704 
Moderate    Inter Info   
[8]
D0384
 
Collagenase clostridium histolyticum
 
NA
 
NA
Moderate    Inter Info   
[96]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1815
 
Icosapent
 
C20H30O2
 
446284 
Moderate    Inter Info   
[11], [134], [135]
D1234
 
Pegaspargase
 
C14H19NO
 
436058 
Moderate    Inter Info   
[93], [21], [11], [94], [136], [137], [138], [139], [140], [141], [142], [143], [144]
D1395
 
Reteplase
 
NA
 
NA
Moderate    Inter Info   
[85], [86], [87], [88], [89], [90], [91], [92]
D1506
 
Streptokinase
 
C11H19NO2
 
9815560 
Moderate    Inter Info   
[85], [87], [92]
D1550
 
Tenecteplase
 
NA
 
NA
Moderate    Inter Info   
[85], [86], [87], [88], [89], [90], [91], [92]
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Moderate    Inter Info   
[91], [145]
D0087
 
Anisindione
 
C16H12O3
 
2197 
Moderate    Inter Info   
[148], [149], [91]
D0113
 
Asparaginase Erwinia chrysanthemi
 
NA
 
NA
Moderate    Inter Info   
[93], [21], [11], [94], [136], [137], [138], [139], [140], [141], [142], [143], [144]
D0210
 
Bromfenac
 
C15H12BrNO3
 
60726 
Moderate    Inter Info   
[91]
D0211
 
Bromfenac (ophthalmic)
 
C15H12BrNO3
 
60726 
Moderate    Inter Info   
[156], [157], [158]
D0232
 
Calaspargase pegol
 
NA
 
NA
Moderate    Inter Info   
[93], [21], [11], [94], [136], [137], [138], [139], [140], [141], [142], [143], [144]
D0298
 
Celecoxib
 
C17H14F3N3O2S
 
2662 
Moderate    Inter Info   
[168]
D0361
 
Clomipramine
 
C19H23ClN2
 
2801 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1769
 
Deoxycholic acid
 
C24H40O4
 
222528 
Moderate    Inter Info   
[50], [184]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D0457
 
Dexfenfluramine
 
C12H16F3N
 
66265 
Moderate    Inter Info   
[100], [128], [129]
D0476
 
Diclofenac
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[91]
D0477
 
Diclofenac (ophthalmic)
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[156], [157], [158]
D0478
 
Diclofenac (topical)
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[156], [157], [158]
D0481
 
Dicoumarol
 
C19H12O6
 
54676038 
Moderate    Inter Info   
[148], [149], [91]
D0489
 
Diflunisal
 
C13H8F2O3
 
3059 
Moderate    Inter Info   
[91]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Moderate    Inter Info   
[188], [189], [190]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Moderate    Inter Info   
[98], [191], [21], [11], [192], [193], [103], [104], [105], [194], [195], [196], [197], [198], [199], [200], [120], [128], [129], [201], [132]
D0624
 
Etodolac
 
C17H21NO3
 
3308 
Moderate    Inter Info   
[91]
D0641
 
Fenfluramine
 
C12H16F3N
 
3337 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Moderate    Inter Info   
[91]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[91]
D0681
 
Flurbiprofen (ophthalmic)
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[156], [157], [158]
D0711
 
Garlic
 
NA
 
NA
Moderate    Inter Info   
[215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229]
D0722
 
Ginkgo biloba
 
NA
 
NA
Moderate    Inter Info   
[230], [231], [232], [233], [217], [234], [235], [218], [220], [221], [236], [237], [238], [224], [239], [240], [241], [227], [242]
D0723
 
Ginseng
 
C42H66O17
 
420552 
Moderate    Inter Info   
[243], [244], [245]
D0752
 
Hemin
 
C34H32FeN4O4
 
26945 
Moderate    Inter Info   
[246]
D0753
 
Heparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[91]
D0786
 
Ibuprofen
 
C13H18O2
 
3672 
Moderate    Inter Info   
[91]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Moderate    Inter Info   
[188], [189], [190]
D0800
 
Indomethacin
 
C19H16ClNO4
 
3715 
Moderate    Inter Info   
[91]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Moderate    Inter Info   
[91]
D0882
 
Ketorolac
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[91]
D0883
 
Ketorolac (ophthalmic)
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[156], [157], [158]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D0988
 
Meclofenamic acid
 
C14H11Cl2NO2
 
4037 
Moderate    Inter Info   
[91]
D0991
 
Mefenamic acid
 
C15H15NO2
 
4044 
Moderate    Inter Info   
[91]
D0995
 
Meloxicam
 
C14H13N3O4S2
 
54677470 
Moderate    Inter Info   
[91]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1097
 
Nabumetone
 
C15H16O2
 
4409 
Moderate    Inter Info   
[91]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Moderate    Inter Info   
[91]
D1123
 
Nepafenac (ophthalmic)
 
C15H14N2O2
 
151075 
Moderate    Inter Info   
[156], [157], [158]
D1139
 
Nintedanib
 
C31H33N5O4
 
135423438 
Moderate    Inter Info   
[248]
D1140
 
Niraparib
 
C19H20N4O
 
24958200 
Moderate    Inter Info   
[11], [249]
D1178
 
Omega-3 fatty acids
 
C60H92O6
 
56842239 
Moderate    Inter Info   
[11], [134], [135]
D1196
 
Oxaprozin
 
C18H15NO3
 
4614 
Moderate    Inter Info   
[91]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1249
 
Pentosan polysulfate
 
C10H18O21S4
 
37720 
Moderate    Inter Info   
[50], [250]
D1251
 
Pentoxifylline
 
C13H18N4O3
 
4740 
Moderate    Inter Info   
[191], [251]
D1274
 
Phenylbutazone
 
C19H20N2O2
 
4781 
Moderate    Inter Info   
[91]
D1421
 
Rofecoxib
 
C17H14O4S
 
5090 
Moderate    Inter Info   
[168]
D1460
 
Selumetinib
 
C17H15BrClFN4O3
 
10127622 
Moderate    Inter Info   
[261], [262], [263]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1464
 
Sibutramine
 
C17H26ClN
 
5210 
Moderate    Inter Info   
[100], [128], [129]
D1520
 
Sulindac
 
C20H17FO3S
 
1548887 
Moderate    Inter Info   
[91]
D1523
 
Suprofen (ophthalmic)
 
C14H12O3S
 
5359 
Moderate    Inter Info   
[156], [157], [158]
D1579
 
Ticagrelor
 
C23H28F2N6O4S
 
9871419 
Moderate    Inter Info   
[11], [266]
D1606
 
Tolmetin
 
C15H15NO3
 
5509 
Moderate    Inter Info   
[91]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Moderate    Inter Info   
[188], [189], [190]
D1674
 
Valdecoxib
 
C16H14N2O3S
 
119607 
Moderate    Inter Info   
[168]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Moderate    Inter Info   
[97], [98], [99], [100], [21], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [28], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132], [133]
D1711
 
Warfarin
 
C19H16O4
 
54678486 
Moderate    Inter Info   
[148], [86], [149], [91]
D1669
 
Urokinase
 
NA
 
NA
Moderate    Inter Info   
[85], [86], [87], [88], [89], [90], [91], [92]
D1703
 
Vitamin E
 
C29H50O2
 
14985 
Moderate    Inter Info   
[261], [272], [11], [273], [274], [275], [276], [220], [277], [278], [279], [280], [281], [282], [283], [262], [284], [285], [263], [286]
D0253
 
Capsicum
 
NA
 
NA
Minor    Inter Info   
[244]
D0309
 
Chamomile
 
C15H10O5
 
5280443 
Minor    Inter Info   
[244], [289], [224]
D0368
 
Clove
 
NA
 
NA
Minor    Inter Info   
[220], [290], [291], [292]
D1661
 
Turmeric
 
C21H20O6
 
969516 
Minor    Inter Info   
[300], [220], [301]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1691
 
Verteporfin
 
C82H84N8O16
 
11980904 
Moderate    Inter Info   
[270], [271]
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142 Product Information. Oncaspar (pegaspargase). Rhone-Poulenc Rorer, Collegeville, PA.
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156 Product Information. Acular (ketorolac). Allergan Inc, Irvine, CA.
157 Product Information. Nevanac (nepafenac ophthalmic). Alcon Laboratories Inc, Fort Worth, TX.
158 Product Information. Xibrom (bromfenac ophthalmic). ISTA Pharmaceuticals, Irvine, CA.
159 Product Information. Aplenzin (buPROPion). sanofi-aventis , Bridgewater, NJ.
160 Product Information. Contrave (buPROPion-naltrexone). Orexigen Therapeutics Inc, La Jolla, CA.
161 Product Information. Forfivo XL (buPROPion (bupropion)). Almatica Pharma Inc, Parsippany, NJ.
162 Product Information. Wellbutrin SR (bupropion). Glaxo Wellcome, Research Triangle Park, NC.
163 Product Information. Wellbutrin XL (buPROPion). GlaxoSmithKline, Philadelphia, PA.
164 Product Information. Zyban (bupropion). Glaxo Wellcome, Research Triangle Park, NC.
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