Details of Drug

Drug General Information (ID: D1914)
Drug Name		Typhoid vaccine (live)
Drug Type		Vaccine
Drug Synonymous		Typhoid Vaccine Live; Salmonella enterica subsp. enterica serovar typhi; Salmonella typhi Ty21a live antigen; Typhoid vaccine (salmonella typhi Ty21a); Typhoid Vaccine Live Ty21a; DB11050 Click to Show/Hide
Therapeutic Class		Vaccine

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM007 Pharmacodynamic antagonistic effects BM100 Antagonize the effect of vaccine/toxoid BM106 Diminish the response to diagnostic skin test antigens
Relation Graph

Full list of drugs interacting with Typhoid vaccine (live)
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 351
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0004		Abatacept	NA	NA	Major		Inter Info	[1], [2], [3]
D0006		Abemaciclib	C27H32F2N8	46220502	Major		Inter Info	[1], [2], [3]
D0008		Acalabrutinib	C26H23N7O2	71226662	Major		Inter Info	[1], [2], [3]
D0023		Adalimumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0027		Aflibercept	NA	NA	Major		Inter Info	[1], [2], [3]
D0030		Aldesleukin	NA	NA	Major		Inter Info	[1], [2], [3]
D0032		Alefacept	NA	NA	Major		Inter Info	[1], [2], [3]
D0033		Alemtuzumab	NA	NA	Major		Inter Info	[4], [5], [1]
D0048		Altretamine	C9H18N6	2123	Major		Inter Info	[1], [2], [3]
D0056		Amikacin	C22H43N5O13	37768	Major		Inter Info	[6], [7], [8]
D0057		Amikacin (liposome)	C22H43N5O13	37768	Major		Inter Info	[6], [7], [8]
D0065		Aminosalicylic acid	C7H7NO3	4649	Major		Inter Info	[6], [7], [8]
D0073		Amoxicillin	C16H19N3O5S	33613	Major		Inter Info	[6], [7], [8]
D0079		Ampicillin	C16H19N3O4S	6249	Major		Inter Info	[6], [7], [8]
D0085		Anakinra	C20H23N5O7S2	146171046	Major		Inter Info	[1], [2], [3]
D0091		Antilymphocyte immunoglobulin (horse)	NA	NA	Major		Inter Info	[1], [2], [3]
D0094		Antithymocyte immunoglobulin (rabbit)	NA	NA	Major		Inter Info	[1], [2], [3]
D0114		Asparaginase Escherichia coli	NA	NA	Major		Inter Info	[1], [2], [3]
D0118		Atezolizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0132		Axicabtagene ciloleucel	NA	NA	Major		Inter Info	[1], [2], [3]
D0134		Azacitidine	C8H12N4O5	9444	Major		Inter Info	[1], [2], [3]
D0136		Azathioprine	C9H7N7O2S	2265	Major		Inter Info	[1], [2], [3]
D0139		Azithromycin	C38H72N2O12	447043	Major		Inter Info	[6], [7], [8]
D0140		Aztreonam	C13H17N5O8S2	5742832	Major		Inter Info	[6], [7], [8]
D0141		Bacampicillin	C21H27N3O7S	441397	Major		Inter Info	[6], [7], [8]
D0142		Bacitracin	C66H103N17O16S	10909430	Major		Inter Info	[6], [7], [8]
D0146		Baricitinib	C16H17N7O2S	44205240	Major		Inter Info	[1], [2], [3]
D0147		Basiliximab	NA	NA	Major		Inter Info	[1], [2], [3]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Major		Inter Info	[6], [7], [8]
D0151		Belatacept	NA	NA	Major		Inter Info	[1], [2], [3]
D0152		Belimumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0153		Belinostat	C15H14N2O4S	6918638	Major		Inter Info	[1], [2], [3]
D0157		Bendamustine	C16H21Cl2N3O2	65628	Major		Inter Info	[1], [2], [3]
D0162		Benznidazole	C12H12N4O3	31593	Major		Inter Info	[6], [7], [8]
D0167		Benzylpenicillin	C16H18N2O4S	5904	Major		Inter Info	[6], [7], [8]
D0168		Benzylpenicillin (potassium)	C16H18N2O4S	5904	Major		Inter Info	[6], [7], [8]
D0169		Benzylpenicillin (sodium)	C16H18N2O4S	5904	Major		Inter Info	[6], [7], [8]
D0172		Betamethasone	C22H29FO5	9782	Major		Inter Info	[1], [2], [3]
D0178		Bexarotene	C24H28O2	82146	Major		Inter Info	[1], [2], [3]
D0190		Bleomycin	C55H84N17O21S3+	5360373	Major		Inter Info	[1], [2], [3]
D0191		Blinatumomab	NA	NA	Major		Inter Info	[1], [2], [3]
D0193		Bortezomib	C19H25BN4O4	387447	Major		Inter Info	[1], [2], [3]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Major		Inter Info	[1], [2], [3]
D0199		Brentuximab vedotin	NA	NA	Major		Inter Info	[1], [2], [3]
D0204		Brigatinib	C29H39ClN7O2P	68165256	Major		Inter Info	[1], [2], [3]
D0209		Brodalumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0223		Busulfan	C6H14O6S2	2478	Major		Inter Info	[1], [2], [3]
D0227		Cabazitaxel	C45H57NO14	9854073	Major		Inter Info	[1], [2], [3]
D0246		Canakinumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0249		Capecitabine	C15H22FN3O6	60953	Major		Inter Info	[1], [2], [3]
D0252		Capreomycin	C50H88N28O15	3000502	Major		Inter Info	[6], [7], [8]
D0257		Carbenicillin	C17H18N2O6S	20824	Major		Inter Info	[6], [7], [8]
D0260		Carboplatin	C6H12N2O4Pt	426756	Major		Inter Info	[1], [2], [3]
D0261		Carfilzomib	C40H57N5O7	11556711	Major		Inter Info	[1], [2], [3]
D0264		Carmustine	C5H9Cl2N3O2	2578	Major		Inter Info	[1], [2], [3]
D0271		Cefaclor	C15H14ClN3O4S	51039	Major		Inter Info	[6], [7], [8]
D0272		Cefadroxil	C16H17N3O5S	47965	Major		Inter Info	[6], [7], [8]
D0273		Cefalotin	C16H16N2O6S2	6024	Major		Inter Info	[6], [7], [8]
D0274		Cefamandole	C18H18N6O5S2	456255	Major		Inter Info	[6], [7], [8]
D0275		Cefapirin	C17H17N3O6S2	30699	Major		Inter Info	[6], [7], [8]
D0276		Cefazolin	C14H14N8O4S3	33255	Major		Inter Info	[6], [7], [8]
D0277		Cefdinir	C14H13N5O5S2	6915944	Major		Inter Info	[6], [7], [8]
D0278		Cefditoren	C19H18N6O5S3	9870843	Major		Inter Info	[6], [7], [8]
D0279		Cefepime	C19H24N6O5S2	5479537	Major		Inter Info	[6], [7], [8]
D0281		Cefixime	C16H15N5O7S2	5362065	Major		Inter Info	[6], [7], [8]
D0282		Cefmetazole	C15H17N7O5S3	42008	Major		Inter Info	[6], [7], [8]
D0283		Cefonicid	C18H18N6O8S3	43594	Major		Inter Info	[6], [7], [8]
D0284		Cefoperazone	C25H27N9O8S2	44187	Major		Inter Info	[6], [7], [8]
D0285		Cefotaxime	C16H17N5O7S2	5742673	Major		Inter Info	[6], [7], [8]
D0286		Cefotetan	C17H17N7O8S4	53025	Major		Inter Info	[6], [7], [8]
D0287		Cefoxitin	C16H17N3O7S2	441199	Major		Inter Info	[6], [7], [8]
D0288		Cefpodoxime	C15H17N5O6S2	6335986	Major		Inter Info	[6], [7], [8]
D0289		Cefprozil	C18H19N3O5S	5281006	Major		Inter Info	[6], [7], [8]
D0290		Cefradine	C16H19N3O4S	38103	Major		Inter Info	[6], [7], [8]
D0291		Ceftaroline fosamil	C22H21N8O8PS4	9852981	Major		Inter Info	[6], [7], [8]
D0292		Ceftazidime	C22H22N6O7S2	5481173	Major		Inter Info	[6], [7], [8]
D0293		Ceftibuten	C15H14N4O6S2	5282242	Major		Inter Info	[6], [7], [8]
D0294		Ceftizoxime	C13H13N5O5S2	6533629	Major		Inter Info	[6], [7], [8]
D0295		Ceftolozane	C23H30N12O8S2	53234134	Major		Inter Info	[6], [7], [8]
D0296		Ceftriaxone	C18H18N8O7S3	5479530	Major		Inter Info	[6], [7], [8]
D0297		Cefuroxime	C16H16N4O8S	5479529	Major		Inter Info	[6], [7], [8]
D0301		Cephalexin	C16H17N3O4S	27447	Major		Inter Info	[6], [7], [8]
D0304		Certolizumab pegol	NA	NA	Major		Inter Info	[1], [2], [3]
D0312		Chlorambucil	C14H19Cl2NO2	2708	Major		Inter Info	[1], [2], [3]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Major		Inter Info	[6], [7], [8]
D0340		Cinoxacin	C12H10N2O5	2762	Major		Inter Info	[6], [7], [8]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Major		Inter Info	[6], [7], [8]
D0344		Cisplatin	Cl2H6N2Pt	5702198	Major		Inter Info	[1], [2], [3]
D0348		Cladribine	C10H12ClN5O3	20279	Major		Inter Info	[1], [2], [3]
D0349		Clarithromycin	C38H69NO13	84029	Major		Inter Info	[6], [7], [8]
D0354		Clindamycin	C18H33ClN2O5S	446598	Major		Inter Info	[6], [7], [8]
D0357		Clofarabine	C10H11ClFN5O3	119182	Major		Inter Info	[1], [2], [3]
D0358		Clofazimine	C27H22Cl2N4	2794	Major		Inter Info	[6], [7], [8]
D0369		Cloxacillin	C19H18ClN3O5S	6098	Major		Inter Info	[6], [7], [8]
D0376		Cobimetinib	C21H21F3IN3O2	16222096	Major		Inter Info	[1], [2], [3]
D0383		Colistimethate	C58H105N16O28S5-5	70789202	Major		Inter Info	[6], [7], [8]
D0389		Copanlisib	C23H28N8O4	135565596	Major		Inter Info	[1], [2], [3]
D0392		Corticotropin	C207H308N56O58S	16132265	Major		Inter Info	[1], [2], [3]
D0400		Cyclophosphamide	C7H15Cl2N2O2P	2907	Major		Inter Info	[1], [2], [3]
D0401		Cycloserine	C3H6N2O2	6234	Major		Inter Info	[6], [7], [8]
D0402		Cyclosporine	C62H111N11O12	5284373	Major		Inter Info	[1], [2], [3]
D0404		Cytarabine	C9H13N3O5	6253	Major		Inter Info	[1], [2], [3]
D0407		Dacarbazine	C6H10N6O	135398738	Major		Inter Info	[1], [2], [3]
D0410		Dactinomycin	C62H86N12O16	457193	Major		Inter Info	[1], [2], [3]
D0411		Dalbavancin	C88H100Cl2N10O28	16134627	Major		Inter Info	[6], [7], [8]
D0419		Dapsone	C12H12N2O2S	2955	Major		Inter Info	[6], [7], [8]
D0421		Daptomycin	C72H101N17O26	16134395	Major		Inter Info	[6], [7], [8]
D0422		Daratumumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Major		Inter Info	[1], [2], [3]
D0429		Daunorubicin	C27H29NO10	30323	Major		Inter Info	[1], [2], [3]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Major		Inter Info	[1], [2], [3]
D0436		Deflazacort	C25H31NO6	189821	Major		Inter Info	[1], [2], [3]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Major		Inter Info	[6], [7], [8]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Major		Inter Info	[6], [7], [8]
D0442		Denileukin diftitox	NA	NA	Major		Inter Info	[1], [2], [3]
D0453		Dexamethasone	C22H29FO5	5743	Major		Inter Info	[1], [2], [3]
D0461		Dexrazoxane	C11H16N4O4	71384	Major		Inter Info	[1], [2], [3]
D0480		Dicloxacillin	C19H17Cl2N3O5S	18381	Major		Inter Info	[6], [7], [8]
D0499		Dimethyl fumarate	C6H8O4	637568	Major		Inter Info	[1], [2], [3]
D0501		Dinutuximab	NA	NA	Major		Inter Info	[1], [2], [3]
D0511		Docetaxel	C43H53NO14	148124	Major		Inter Info	[1], [2], [3]
D0519		Doripenem	C15H24N4O6S2	73303	Major		Inter Info	[6], [7], [8]
D0528		Doxorubicin	C27H29NO11	31703	Major		Inter Info	[1], [2], [3]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Major		Inter Info	[1], [2], [3]
D0530		Doxycycline	C22H24N2O8	54671203	Major		Inter Info	[6], [7], [8]
D0540		Dupilumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0541		Durvalumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0543		Duvelisib	C22H17ClN6O	50905713	Major		Inter Info	[1], [2], [3]
D0553		Efalizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0560		Elotuzumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0571		Enfortumab vedotin	NA	NA	Major		Inter Info	[1], [2], [3]
D0573		Enoxacin	C15H17FN4O3	3229	Major		Inter Info	[6], [7], [8]
D0584		Epirubicin	C27H29NO11	41867	Major		Inter Info	[1], [2], [3]
D0589		Eravacycline	C27H31FN4O8	54726192	Major		Inter Info	[6], [7], [8]
D0594		Eribulin	C40H59NO11	11354606	Major		Inter Info	[1], [2], [3]
D0596		Ertapenem	C22H25N3O7S	150610	Major		Inter Info	[6], [7], [8]
D0614		Etanercept	NA	NA	Major		Inter Info	[1], [2], [3]
D0616		Ethambutol	C10H24N2O2	14052	Major		Inter Info	[6], [7], [8]
D1731		Ethionamide	C8H10N2S	2761171	Major		Inter Info	[6], [7], [8]
D0627		Etoposide	C29H32O13	36462	Major		Inter Info	[1], [2], [3]
D0629		Everolimus	C53H83NO14	6442177	Major		Inter Info	[1], [2], [3]
D0658		Fidaxomicin	C52H74Cl2O18	10034073	Major		Inter Info	[6], [7], [8]
D0661		Fingolimod	C19H33NO2	107970	Major		Inter Info	[4], [9], [10]
D0666		Floxuridine	C9H11FN2O5	5790	Major		Inter Info	[1], [2], [3]
D0669		Fludarabine	C10H12FN5O4	657237	Major		Inter Info	[1], [2], [3]
D0671		Fludrocortisone	C21H29FO5	31378	Major		Inter Info	[1], [2], [3]
D0675		Fluorouracil	C4H3FN2O2	3385	Major		Inter Info	[1], [2], [3]
D1790		Fosfomycin	C3H7O4P	446987	Major		Inter Info	[6], [7], [8]
D0712		Gatifloxacin	C19H22FN3O4	5379	Major		Inter Info	[6], [7], [8]
D0714		Gemcitabine	C9H11F2N3O4	60750	Major		Inter Info	[1], [2], [3]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Major		Inter Info	[6], [7], [8]
D0717		Gemtuzumab ozogamicin	NA	NA	Major		Inter Info	[1], [2], [3]
D0718		Gentamicin	C21H43N5O7	3467	Major		Inter Info	[6], [7], [8]
D0736		Golimumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0740		Grepafloxacin	C19H22FN3O3	72474	Major		Inter Info	[6], [7], [8]
D0747		Guselkumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0773		Hydrocortisone	C21H30O5	5754	Major		Inter Info	[1], [2], [3]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Major		Inter Info	[6], [7], [8]
D0780		Hydroxyurea	CH4N2O2	3657	Major		Inter Info	[1], [2], [3]
D0784		Ibritumomab tiuxetan	NA	NA	Major		Inter Info	[1], [2], [3]
D0785		Ibrutinib	C25H24N6O2	24821094	Major		Inter Info	[1], [2], [3]
D0788		Idarubicin	C26H27NO9	42890	Major		Inter Info	[1], [2], [3]
D0789		Idelalisib	C22H18FN7O	11625818	Major		Inter Info	[1], [2], [3]
D0790		Ifosfamide	C7H15Cl2N2O2P	3690	Major		Inter Info	[1], [2], [3]
D0793		Imatinib	C29H31N7O	5291	Major		Inter Info	[1], [2], [3]
D0794		Imipenem	C12H17N3O4S	104838	Major		Inter Info	[6], [7], [8]
D0801		Inebilizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0802		Infliximab	NA	NA	Major		Inter Info	[1], [2], [3]
D0806		Inotuzumab ozogamicin	NA	NA	Major		Inter Info	[1], [2], [3]
D0829		Iobenguane (I-131)	C8H10IN3	60860	Major		Inter Info	[1], [2], [3]
D0845		Irinotecan	C33H38N4O6	60838	Major		Inter Info	[1], [2], [3]
D0846		Irinotecan (liposomal)	C33H38N4O6	60838	Major		Inter Info	[1], [2], [3]
D0858		Isoniazid	C6H7N3O	3767	Major		Inter Info	[6], [7], [8]
D0873		Ixabepilone	C27H42N2O5S	6445540	Major		Inter Info	[1], [2], [3]
D0874		Ixazomib	C14H19BCl2N2O4	25183872	Major		Inter Info	[1], [2], [3]
D0875		Ixekizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D0876		Kanamycin	C18H36N4O11	6032	Major		Inter Info	[6], [7], [8]
D0900		Leflunomide	C12H9F3N2O2	3899	Major		Inter Info	[1], [2], [3]
D0902		Lenalidomide	C13H13N3O3	216326	Major		Inter Info	[1], [2], [3]
D0910		Levamisole	C11H12N2S	26879	Major		Inter Info	[1], [2], [3]
D0919		Levofloxacin	C18H20FN3O4	149096	Major		Inter Info	[6], [7], [8]
D0931		Lincomycin	C18H34N2O6S	3000540	Major		Inter Info	[6], [7], [8]
D0933		Linezolid	C16H20FN3O4	441401	Major		Inter Info	[6], [7], [8]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Major		Inter Info	[6], [7], [8]
D0945		Lomustine	C9H16ClN3O2	3950	Major		Inter Info	[1], [2], [3]
D0949		Loracarbef	C16H16ClN3O4	5284585	Major		Inter Info	[6], [7], [8]
D0962		Lurbinectedin	C41H44N4O10S	57327016	Major		Inter Info	[1], [2], [3]
D0964		Lutetium Lu 177 dotatate	C65H87LuN14O19S2	76966897	Major		Inter Info	[1], [2], [3]
D0986		Mechlorethamine	C5H11Cl2N	4033	Major		Inter Info	[1], [2], [3]
D0996		Melphalan	C13H18Cl2N2O2	460612	Major		Inter Info	[1], [2], [3]
D1007		Mercaptopurine	C5H4N4S	667490	Major		Inter Info	[1], [2], [3]
D1008		Meropenem	C17H25N3O5S	441130	Major		Inter Info	[6], [7], [8]
D1025		Methotrexate	C20H22N8O5	126941	Major		Inter Info	[1], [2], [3]
D1041		Methylprednisolone	C22H30O5	6741	Major		Inter Info	[1], [2], [3]
D1044		Meticillin	C17H20N2O6S	6087	Major		Inter Info	[6], [7], [8]
D1051		Metronidazole	C6H9N3O3	4173	Major		Inter Info	[6], [7], [8]
D1055		Mezlocillin	C21H25N5O8S2	656511	Major		Inter Info	[6], [7], [8]
D1062		Midostaurin	C35H30N4O4	9829523	Major		Inter Info	[1], [2], [3]
D1070		Minocycline	C23H27N3O7	54675783	Major		Inter Info	[6], [7], [8]
D1077		Mitomycin	C15H18N4O5	5746	Major		Inter Info	[1], [2], [3]
D1079		Mitoxantrone	C22H28N4O6	4212	Major		Inter Info	[1], [2], [3]
D1083		Mogamulizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1092		Moxifloxacin	C21H24FN3O4	152946	Major		Inter Info	[6], [7], [8]
D1093		Muromonab	NA	NA	Major		Inter Info	[1], [2], [3]
D1094		Mycophenolate mofetil	C23H31NO7	5281078	Major		Inter Info	[1], [2], [3]
D1095		Mycophenolic acid	C17H20O6	446541	Major		Inter Info	[1], [2], [3]
D1099		Nafcillin	C21H22N2O5S	8982	Major		Inter Info	[6], [7], [8]
D1102		Nalidixic acid	C12H12N2O3	4421	Major		Inter Info	[6], [7], [8]
D1111		Natalizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1118		Nelarabine	C11H15N5O5	3011155	Major		Inter Info	[1], [2], [3]
D1120		Neomycin	C23H46N6O13	8378	Major		Inter Info	[6], [7], [8]
D1126		Netilmicin	C21H41N5O7	441306	Major		Inter Info	[6], [7], [8]
D1136		Nilotinib	C28H22F3N7O	644241	Major		Inter Info	[1], [2], [3]
D1140		Niraparib	C19H20N4O	24958200	Major		Inter Info	[1], [2], [3]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Major		Inter Info	[6], [7], [8]
D1155		Norfloxacin	C16H18FN3O3	4539	Major		Inter Info	[6], [7], [8]
D1159		Novobiocin	C31H36N2O11	54675769	Major		Inter Info	[6], [7], [8]
D1161		Obinutuzumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1162		Ocrelizumab	NA	NA	Major		Inter Info	[4], [11], [1]
D1164		Ofatumumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1165		Ofloxacin	C18H20FN3O4	4583	Major		Inter Info	[6], [7], [8]
D1167		Olaparib	C24H23FN4O3	23725625	Major		Inter Info	[1], [2], [3]
D1168		Olaratumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Major		Inter Info	[1], [2], [3]
D1175		Omadacycline	C29H40N4O7	54697325	Major		Inter Info	[6], [7], [8]
D1186		Oritavancin	C86H97Cl3N10O26	16136912	Major		Inter Info	[6], [7], [8]
D1190		Osimertinib	C28H33N7O2	71496458	Major		Inter Info	[1], [2], [3]
D1192		Oxacillin	C19H19N3O5S	6196	Major		Inter Info	[6], [7], [8]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Major		Inter Info	[1], [2], [3]
D1209		Oxytetracycline	C22H24N2O9	54675779	Major		Inter Info	[6], [7], [8]
D1211		Ozanimod	C23H24N4O3	52938427	Major		Inter Info	[12]
D1212		Paclitaxel	C47H51NO14	36314	Major		Inter Info	[1], [2], [3]
D1213		Paclitaxel (protein-bound)	C47H51NO14	36314	Major		Inter Info	[1], [2], [3]
D1214		Palbociclib	C24H29N7O2	5330286	Major		Inter Info	[1], [2], [3]
D1221		Panobinostat	C21H23N3O2	6918837	Major		Inter Info	[1], [2], [3]
D1228		Paromomycin	C23H45N5O14	165580	Major		Inter Info	[6], [7], [8]
D1232		Pazopanib	C21H23N7O2S	10113978	Major		Inter Info	[1], [2], [3]
D1234		Pegaspargase	C14H19NO	436058	Major		Inter Info	[1], [2], [3]
D1241		Pemetrexed	C20H21N5O6	135410875	Major		Inter Info	[1], [2], [3]
D1246		Pentamidine	C19H24N4O2	4735	Major		Inter Info	[6], [7], [8]
D1250		Pentostatin	C11H16N4O4	439693	Major		Inter Info	[1], [2], [3]
D1268		Phenoxymethylpenicillin	C16H18N2O5S	6869	Major		Inter Info	[6], [7], [8]
D1296		Piperacillin	C23H27N5O7S	43672	Major		Inter Info	[6], [7], [8]
D1304		Plazomicin	C25H48N6O10	42613186	Major		Inter Info	[6], [7], [8]
D1305		Plicamycin	C52H76O24	163659	Major		Inter Info	[1], [2], [3]
D1306		Polatuzumab vedotin	NA	NA	Major		Inter Info	[1], [2], [3]
D1310		Polymyxin B	C56H98N16O13	49800004	Major		Inter Info	[6], [7], [8]
D1312		Pomalidomide	C13H11N3O4	134780	Major		Inter Info	[1], [2], [3]
D1313		Ponatinib	C29H27F3N6O	24826799	Major		Inter Info	[1], [2], [3]
D1323		Pralatrexate	C23H23N7O5	148121	Major		Inter Info	[1], [2], [3]
D1332		Prednisolone	C21H28O5	5755	Major		Inter Info	[1], [2], [3]
D1334		Prednisone	C21H26O5	5865	Major		Inter Info	[1], [2], [3]
D1339		Primaquine	C15H21N3O	4908	Major		Inter Info	[6], [7], [8]
D1345		Procarbazine	C12H19N3O	4915	Major		Inter Info	[1], [2], [3]
D1364		Pyrazinamide	C5H5N3O	1046	Major		Inter Info	[6], [7], [8]
D1372		Quinine	C20H24N2O2	3034034	Major		Inter Info	[6], [7], [8]
D1874		Quinupristin	C53H67N9O10S	5388937	Major		Inter Info	[6], [7], [8]
D1398		Ribociclib	C23H30N8O	44631912	Major		Inter Info	[1], [2], [3]
D1399		Rifabutin	C46H62N4O11	135398743	Major		Inter Info	[6], [7], [8]
D1400		Rifampicin	C43H58N4O12	135398735	Major		Inter Info	[6], [7], [8]
D1879		Rifamycin	C37H47NO12	6324616	Major		Inter Info	[6], [7], [8]
D1401		Rifapentine	C47H64N4O12	135403821	Major		Inter Info	[6], [7], [8]
D1402		Rifaximin	C43H51N3O11	6436173	Major		Inter Info	[6], [7], [8]
D1403		Rilonacept	NA	NA	Major		Inter Info	[1], [2], [3]
D1416		Rituximab	NA	NA	Major		Inter Info	[1], [2], [3]
D1424		Romidepsin	C24H36N4O6S2	5352062	Major		Inter Info	[1], [2], [3]
D1432		Rucaparib	C19H18FN3O	9931954	Major		Inter Info	[1], [2], [3]
D1434		Ruxolitinib	C17H18N6	25126798	Major		Inter Info	[1], [2], [3]
D1445		Sarecycline	C24H29N3O8	54681908	Major		Inter Info	[6], [7], [8]
D1447		Sarilumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1452		Secnidazole	C7H11N3O3	71815	Major		Inter Info	[6], [7], [8]
D1454		Secukinumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1458		Selinexor	C17H11F6N7O	71481097	Major		Inter Info	[1], [2], [3]
D1467		Siltuximab	NA	NA	Major		Inter Info	[1], [2], [3]
D1474		Siponimod	C29H35F3N2O3	44599207	Major		Inter Info	[11], [13]
D1476		Sirolimus	C51H79NO13	5284616	Major		Inter Info	[1], [2], [3]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Major		Inter Info	[6], [7], [8]
D1500		Spectinomycin	C14H24N2O7	15541	Major		Inter Info	[6], [7], [8]
D1507		Streptomycin	C21H39N7O12	19649	Major		Inter Info	[6], [7], [8]
D1508		Streptozocin	C8H15N3O7	29327	Major		Inter Info	[1], [2], [3]
D1513		Sulfadiazine	C10H10N4O2S	5215	Major		Inter Info	[6], [7], [8]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Major		Inter Info	[6], [7], [8]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Major		Inter Info	[6], [7], [8]
D1519		Sulfisoxazole	C11H13N3O3S	5344	Major		Inter Info	[6], [7], [8]
D1526		Tacrolimus	C44H69NO12	445643	Major		Inter Info	[1], [2], [3]
D1530		Tafenoquine	C24H28F3N3O3	115358	Major		Inter Info	[6], [7], [8]
D1532		Talazoparib	C19H14F2N6O	135565082	Major		Inter Info	[1], [2], [3]
D1542		Telavancin	C80H106Cl2N11O27P	3081362	Major		Inter Info	[6], [7], [8]
D1544		Telithromycin	C43H65N5O10	3002190	Major		Inter Info	[6], [7], [8]
D1548		Temozolomide	C6H6N6O2	5394	Major		Inter Info	[1], [2], [3]
D1549		Temsirolimus	C56H87NO16	6918289	Major		Inter Info	[1], [2], [3]
D1551		Teniposide	C32H32O13S	452548	Major		Inter Info	[1], [2], [3]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Major		Inter Info	[1], [2], [3]
D1564		Tetracycline	C22H24N2O8	54675776	Major		Inter Info	[6], [7], [8]
D1569		Thalidomide	C13H10N2O4	5426	Major		Inter Info	[1], [2], [3]
D1575		Thiotepa	C6H12N3PS	5453	Major		Inter Info	[1], [2], [3]
D1580		Ticarcillin	C15H16N2O6S2	36921	Major		Inter Info	[6], [7], [8]
D1582		Tigecycline	C29H39N5O8	54686904	Major		Inter Info	[6], [7], [8]
D1583		Tildrakizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1587		Tinidazole	C8H13N3O4S	5479	Major		Inter Info	[6], [7], [8]
D1589		Tioguanine	C5H5N5S	2723601	Major		Inter Info	[1], [2], [3]
D1594		Tisagenlecleucel	NA	NA	Major		Inter Info	[1], [2], [3]
D1597		Tobramycin	C18H37N5O9	36294	Major		Inter Info	[6], [7], [8]
D1599		Tocilizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1600		Tofacitinib	C16H20N6O	9926791	Major		Inter Info	[1], [2], [3]
D1610		Topotecan	C23H23N3O5	60700	Major		Inter Info	[1], [2], [3]
D1613		Tositumomab	NA	NA	Major		Inter Info	[1], [2], [3]
D1614		Tositumomab (I-131)	NA	NA	Major		Inter Info	[1], [2], [3]
D1615		Trabectedin	C39H43N3O11S	108150	Major		Inter Info	[1], [2], [3]
D1621		Trastuzumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1628		Triamcinolone	C21H27FO6	31307	Major		Inter Info	[1], [2], [3]
D1639		Trifluridine	C10H11F3N2O5	6256	Major		Inter Info	[1], [2], [3]
D1645		Trimethoprim	C14H18N4O3	5578	Major		Inter Info	[6], [7], [8]
D1646		Trimetrexate	C19H23N5O3	5583	Major		Inter Info	[1], [2], [3]
D1653		Troleandomycin	C41H67NO15	202225	Major		Inter Info	[6], [7], [8]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Major		Inter Info	[6], [7], [8]
D0129		Avapritinib	C26H27FN10	118023034	Major		Inter Info	[1], [2], [3]
D0150		Belantamab mafodotin	NA	NA	Major		Inter Info	[1], [2], [3]
D0203		Brexucabtagene autoleucel	NA	NA	Major		Inter Info	[1], [2], [3]
D0280		Cefiderocol	C30H34ClN7O10S2	77843966	Major		Inter Info	[6], [7], [8]
D0507		Diroximel fumarate	C11H13NO6	73330464	Major		Inter Info	[1], [2], [3]
D0564		Emapalumab	NA	NA	Major		Inter Info	[14]
D0851		Isatuximab	NA	NA	Major		Inter Info	[1], [2], [3]
D0939		Lisocabtagene maraleucel	NA	NA	Major		Inter Info	[1], [2], [3]
D0997		Melphalan flufenamide	C24H30Cl2FN3O3	9935639	Major		Inter Info	[1], [2], [3]
D1085		Monomethyl fumarate	C5H6O4	5369209	Major		Inter Info	[1], [2], [3]
D1113		Naxitamab	NA	NA	Major		Inter Info	[1], [2], [3]
D1410		Risankizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1448		Satralizumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1529		Tafasitamab	NA	NA	Major		Inter Info	[1], [2], [3]
D1539		Tedizolid	C17H15FN6O3	11234049	Major		Inter Info	[6], [7], [8]
D1622		Trastuzumab deruxtecan	NA	NA	Major		Inter Info	[1], [2], [3]
D1666		Upadacitinib	C17H19F3N6O	58557659	Major		Inter Info	[1], [2], [3]
D1718		Zanubrutinib	C27H29N5O3	135565884	Major		Inter Info	[1], [2], [3]
D1667		Uracil mustard	C8H11Cl2N3O2	6194	Major		Inter Info	[1], [2], [3]
D1671		Ustekinumab	NA	NA	Major		Inter Info	[1], [2], [3]
D1680		Vancomycin	C66H75Cl2N9O24	14969	Major		Inter Info	[6], [7], [8]
D1685		Vedolizumab	NA	NA	Major		Inter Info	[4], [15], [1]
D1688		Venetoclax	C45H50ClN7O7S	49846579	Major		Inter Info	[1], [2], [3]
D1697		Vinblastine	C46H58N4O9	13342	Major		Inter Info	[1], [2], [3]
D1698		Vincristine	C46H56N4O10	5978	Major		Inter Info	[1], [2], [3]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Major		Inter Info	[1], [2], [3]
D1700		Vinorelbine	C45H54N4O8	5311497	Major		Inter Info	[1], [2], [3]
D0215		Budesonide	C25H34O6	5281004	Moderate		Inter Info	[1], [2], [16]
D1350		Proguanil	C11H16ClN5	6178111	Moderate		Inter Info	[20], [21], [22]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[1], [2], [16]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[1], [2], [16]
D0320		Chloroquine	C18H26ClN3	2719	Minor		Inter Info	[11], [23], [22]
D0828		Interferon gamma-1b	NA	NA	Minor		Inter Info	[11], [6]
D0992		Mefloquine	C17H16F6N2O	4046	Minor		Inter Info	[11], [23], [22]
D1514		Sulfadoxine	C12H14N4O4S	17134	Minor		Inter Info	[11], [23], [22]
	Diminish the response to diagnostic skin test antigens					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1755		Candida albicans	C29H27N2O12P	118855431	Moderate		Inter Info	[17], [18], [19]
D1765		Coccidioides immitis spherule	NA	NA	Moderate		Inter Info	[17], [18], [19]
D1912		Trichophyton mentagrophytes	NA	NA	Moderate		Inter Info	[17], [18], [19]
D1913		Tuberculin purified protein derivative	NA	NA	Moderate		Inter Info	[17], [18], [19]

References
1	Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. "Harrison's Principles of Internal Medicine. 14th ed." New York, NY: McGraw-Hill Health Professionals Division (1998).
2	Product Information. Attenuvax (measles virus vaccine, live, attenuated). Merck &amp Co, Inc, West Point, PA.
3	Product Information. YF-Vax (yellow fever vaccine). sanofi pasteur, Swiftwater, PA.
4	CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
5	Product Information. Campath (alemtuzumab) Berlex, Richmond, CA.
6	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
7	UK government "Typhoid.".
8	American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association (1994).
9	Product Information. Gilenya (fingolimod). Novartis Pharmaceuticals, East Hanover, NJ.
10	Product Information. Meruvax II (rubella virus vaccine, live). Merck &amp Co, Inc, West Point, PA.
11	Cerner Multum, Inc. "Australian Product Information.".
12	Product Information. Zeposia (ozanimod). Celgene Corporation, Summit, NJ.
13	Product Information. Mayzent (siponimod). Novartis Pharmaceuticals, East Hanover, NJ.
14	Product Information. Gamifant (emapalumab). Sobi Inc, Ardmore, PA.
15	Product Information. Entyvio (vedolizumab). Takeda Pharmaceuticals America, Lincolnshire, IL.
16	Product Information. Orimune (poliovirus vaccine, live, oral, trivalent). Lederle Laboratories, Philadelphia, PA.
17	Product Information. Tuberculin PPD (Mantoux) (tuberculin purified protein derivative). Connaught Laboratories Ltd, Toronto, ON.
18	Product Information. Multitest CMI (skin test antigens, multiple). Aventis Pharmaceuticals, Swiftwater, PA.
19	Product Information. MSTA Mumps Skin Test Antigen (mumps skin test antigen). Aventis Pharmaceuticals, Swiftwater, PA.
20	Product Information. Malarone (atovaquone-proguanil) Glaxo Wellcome, Research Triangle Pk, NC.
21	Wohlt PD, Zheng L, Gunderson S, Balzar SA, Johnson BD, Fish JT "Recommendations for the use of medications with continuous enteral nutrition." Am J Health Syst Pharm 66 (2009): 1438-67. [PMID: 19667002]
22	Product Information. Vivotif Berna (typhoid vaccine, live) Crucell Vaccine Inc, Coral Gables, FL.
23	Kollaritsch H, Que JU, Kunz C, Wiedermann G, Herzog C, Cryz SJ Jr "Safety and immunogenicity of live oral cholera and typhoid vaccines administered alone or in combination with antimalarial drugs, oral polio vaccine, or yellow fever vaccine." J Infect Dis 175 (1997): 871-5. [PMID: 9086143]

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