Details of Drug

Details of Drug

 Drug General Information (ID: D1753)
  Drug Name
Calcipotriol (topical)
  Drug Type Small molecule
  Drug Synonymous
Calcipotriene; Divonex; Dovonex; BMS-181161; Daivonex (TN); Dovonex (TN); MC-903; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol; (1S,5Z,7Z,17ALPHA,22E)-24-CYCLOPROPYL-9,10-SECOCHOLA-5,7,10,22-TETRAENE-1,3,24-TRIOL; 1-ALPHA,24S-(OH)2-22-ENE-26,27-DEHYDROVITAMIN D3
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  Disease Class EA90: Psoriasis
  Therapeutic Class Antipsoriatic Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C27H40O3
  InChI 1S/C27H40O3/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23,24)3)7-10-21-15-22(28)16-26(30)18(21)2/h6-7,10,13,17,20,22-26,28-30H,2,4-5,8-9,11-12,14-16H2,1,3H3/b13-6+,19-7+,21-10-/t17-,22-,23-,24+,25-,26+,27-/m1/s1
  InChIKey LWQQLNNNIPYSNX-UROSTWAQSA-N
  Canonical SMILES CC(C=CC(C1CC1)O)C2CCC3C2(CCCC3=CC=C4CC(CC(C4=C)O)O)C
  External Link
Pubchem ID 5288783
CAS Number CAS 112965-21-6
CHEBI ID CHEBI:50749
TTD ID D01QUS

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM107  Attenuated pharmacological effects (Unspecific)
BM108  Increased risk of hypercalcemia
  Relation Graph
 Full list of drugs interacting with Calcipotriol (topical)
      Pharmacodynamic additive effects
   Increased risk of hypercalcemia Drug Num:  50
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0158
 
Bendroflumethiazide
 
C15H14F3N3O4S2
 
2315 
Moderate    Inter Info   
[2], [3]
D0166
 
Benzthiazide
 
C15H14ClN3O4S3
 
2343 
Moderate    Inter Info   
[2], [3]
D0233
 
Calcifediol
 
C27H44O2
 
5283731 
Moderate    Inter Info   
[2], [3]
D1732
 
Abaloparatide
 
C174H300N56O49
 
145705876 
Moderate    Inter Info   
[2], [3]
D0236
 
Calcium carbonate
 
CCaO3
 
10112 
Moderate    Inter Info   
[2], [3]
D0238
 
Calcium citrate
 
C12H10Ca3O14
 
13136 
Moderate    Inter Info   
[2], [3]
D0239
 
Calcium glubionate anhydrous
 
C18H32CaO19
 
64776 
Moderate    Inter Info   
[2], [3]
D0241
 
Calcium gluconate
 
C12H22CaO14
 
9290 
Moderate    Inter Info   
[2], [3]
D0242
 
Calcium glycerophosphate
 
C3H7CaO6P
 
120096 
Moderate    Inter Info   
[2], [3]
D0243
 
Calcium lactate
 
C6H10CaO6
 
13144 
Moderate    Inter Info   
[2], [3]
D0244
 
Calcium Phosphate
 
Ca3O8P2
 
24456 
Moderate    Inter Info   
[2], [3]
D0527
 
Doxercalciferol
 
C28H44O2
 
5281107 
Moderate    Inter Info   
[2], [3]
D0605
 
Esterified estrogens
 
NA
 
NA
Moderate    Inter Info   
[2], [3]
D0610
 
Estrone sulfate
 
C18H22O5S
 
3001028 
Moderate    Inter Info   
[2], [3]
D0611
 
Estrone sulfate (topical)
 
C18H22O5S
 
3001028 
Moderate    Inter Info   
[2], [3]
D1042
 
Methyltestosterone
 
C20H30O2
 
6010 
Moderate    Inter Info   
[2], [3]
D1207
 
Oxymetholone
 
C21H32O3
 
5281034 
Moderate    Inter Info   
[2], [3]
D1857
 
Parathyroid hormone
 
NA
 
NA
Moderate    Inter Info   
[2], [3]
D1327
 
Prasterone enantate
 
C26H40O3
 
163331 
Moderate    Inter Info   
[2], [3]
D1370
 
Quinestrol
 
C25H32O2
 
9046 
Moderate    Inter Info   
[2], [3]
D1503
 
Stanozolol
 
C21H32N2O
 
25249 
Moderate    Inter Info   
[2], [3]
D1901
 
Teriparatide
 
C181H291N55O51S2
 
16133850 
Moderate    Inter Info   
[2], [3]
D0234
 
Calcitriol
 
C27H44O3
 
5280453 
Moderate    Inter Info   
[2], [3]
D0235
 
Calcium acetate
 
C4H6CaO4
 
6116 
Moderate    Inter Info   
[2], [3]
D0237
 
Calcium chloride
 
CaCl2H4O2
 
24844 
Moderate    Inter Info   
[2], [3]
D0240
 
Calcium glucoheptonate
 
C14H26CaO16
 
62859 
Moderate    Inter Info   
[2], [3]
D0321
 
Chlorothiazide
 
C7H6ClN3O4S2
 
2720 
Moderate    Inter Info   
[2], [3]
D0326
 
Chlorthalidone
 
C14H11ClN2O4S
 
2732 
Moderate    Inter Info   
[2], [3]
D0328
 
Cholecalciferol
 
C27H44O
 
5280795 
Moderate    Inter Info   
[2], [3]
D0387
 
Conjugated estrogens
 
C18H21NaO5S
 
45357473 
Moderate    Inter Info   
[2], [3]
D0388
 
Conjugated estrogens (topical)
 
C18H21NaO5S
 
45357473 
Moderate    Inter Info   
[2], [3]
D0484
 
Dienestrol (topical)
 
C18H18O2
 
667476 
Moderate    Inter Info   
[2], [3]
D0487
 
Diethylstilbestrol
 
C18H20O2
 
448537 
Moderate    Inter Info   
[2], [3]
D0495
 
Dihydrotachysterol
 
C28H46O
 
5311071 
Moderate    Inter Info   
[2], [3]
D0606
 
Estradiol
 
C18H24O2
 
5757 
Moderate    Inter Info   
[2], [3]
D0607
 
Estradiol (topical)
 
C18H24O2
 
5757 
Moderate    Inter Info   
[2], [3]
D0608
 
Estramustine
 
C23H31Cl2NO3
 
259331 
Moderate    Inter Info   
[2], [3]
D0609
 
Estrone
 
C18H22O2
 
5870 
Moderate    Inter Info   
[2], [3]
D0677
 
Fluoxymesterone
 
C20H29FO3
 
6446 
Moderate    Inter Info   
[2], [3]
D0771
 
Hydrochlorothiazide
 
C7H8ClN3O4S2
 
3639 
Moderate    Inter Info   
[2], [3]
D0775
 
Hydroflumethiazide
 
C8H8F3N3O4S2
 
3647 
Moderate    Inter Info   
[2], [3]
D0798
 
Indapamide
 
C16H16ClN3O3S
 
3702 
Moderate    Inter Info   
[2], [3]
D1048
 
Metolazone
 
C16H16ClN3O3S
 
4170 
Moderate    Inter Info   
[2], [3]
D1195
 
Oxandrolone
 
C19H30O3
 
5878 
Moderate    Inter Info   
[2], [3]
D1226
 
Paricalcitol
 
C27H44O3
 
5281104 
Moderate    Inter Info   
[2], [3]
D1311
 
Polythiazide
 
C11H13ClF3N3O4S3
 
4870 
Moderate    Inter Info   
[2], [3]
D1557
 
Testolactone
 
C19H24O3
 
13769 
Moderate    Inter Info   
[2], [3]
D1558
 
Testosterone
 
C19H28O2
 
6013 
Moderate    Inter Info   
[2], [3]
D1559
 
Testosterone (topical)
 
C19H28O2
 
6013 
Moderate    Inter Info   
[2], [3]
D1633
 
Trichlormethiazide
 
C8H8Cl3N3O4S2
 
5560 
Moderate    Inter Info   
[2], [3]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0590
 
Erdafitinib
 
C25H30N6O2
 
67462786 
Major    Inter Info   
[1]
References
1 Product Information. Balversa (erdafitinib). Janssen Products, LP, Horsham, PA.
2 Product Information. Vectical (calcitriol topical). Galderma Laboratories Inc, Cranbury, NJ.
3 Product Information. Dovonex (calcipotriene). Westwood Squibb Pharmaceutical Corporation, Eatontown, NJ.