Details of Drug

Details of Drug

 Drug General Information (ID: D1683)
  Drug Name
Vasopressin
  Drug Type Small molecule
  Drug Synonymous
Leiormone; Pitressin; Pituitrin; Tonephin; Vasopressina; Vasopressine; Vasopressins; Vasopressinum; American Pharmaceutical Brand of Vasopressin; American Regent Brand of Vasopressin; Antidiuretic Hormones; Antidiuretic hormone; Beta Hypophamine; Inyectable de vasopresina; Monarch Brand of Vasopressin; Solute injectable de vasopressine; Vasopressin Monarch Brand; Vasopressin injection; Vasopressina [DCIT]; Vasopressini injectio; ADH (hormone); Beta-Hypophamine; Inyectable de vasopresina [INN-Spanish]; Pitressin (TN); Solute injectable de vasopressine [INN-French]; Vasopressin (USP); Vasopressini injectio [INN-Latin]; Parke-Davis Brand of Vasopressin (USP); Vasopressin (JP15/USP)
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  Disease Class 5A60-5A61: Pituitary gland disorder; MF55: Polyuria; 6C00: Enuresis
  Therapeutic Class Vasoconstrictor Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C46H65N15O12S2
  InChI 1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1
  InChIKey KBZOIRJILGZLEJ-LGYYRGKSSA-N
  Canonical SMILES C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N
  External Link
Pubchem ID 644077
CAS Number 113-79-1
CHEBI ID 34543
TTD ID D0N4OW
VARIDT ID DR00247

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM014  Interference of cell/tissue uptake
BM038  Additive CNS depression effects
BM041  Additive hypertensive effects
BM049  Increased risk of atrioventricular block
BM067  Increased risk of hyponatremia
BM076  Increased risk of prolong QT interval
BM078  Increased risk of rapid heart rate
BM081  Increased risk of ventricular arrhythmias
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Vasopressin
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1906
 
Thallous Chloride
 
ClTl
 
24642 
Moderate    Inter Info   
[2], [435], [436]
      Pharmacodynamic additive effects
   Additive CNS depression effects Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0452
 
Deutetrabenazine
 
C19H27NO3
 
73437646 
Moderate    Inter Info   
[380]
D1673
 
Valbenazine
 
C24H38N2O4
 
24795069 
Moderate    Inter Info   
[442]
   Additive hypertensive effects Drug Num:  7
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0510
 
Dobutamine
 
C18H23NO3
 
36811 
Moderate    Inter Info   
[281], [294], [381]
D0517
 
Dopamine
 
C8H11NO2
 
681 
Moderate    Inter Info   
[281], [294], [381]
D0581
 
Epinephrine
 
C9H13NO3
 
5816 
Moderate    Inter Info   
[281], [294], [381]
D0879
 
Ketamine
 
C13H16ClNO
 
3821 
Moderate    Inter Info   
[2], [3], [393]
D0983
 
Mecamylamine
 
C11H21N
 
4032 
Moderate    Inter Info   
[2], [3], [241]
D1153
 
Norepinephrine
 
C8H11NO3
 
439260 
Moderate    Inter Info   
[281], [294], [381]
D1643
 
Trimethaphan
 
C22H25N2OS+
 
23576 
Moderate    Inter Info   
[2], [3], [241]
   Increased risk of atrioventricular block Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0992
 
Mefloquine
 
C17H16F6N2O
 
4046 
Moderate    Inter Info   
[3], [83], [403]
   Increased risk of hyponatremia Drug Num:  52
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0210
 
Bromfenac
 
C15H12BrNO3
 
60726 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0255
 
Carbamazepine
 
C15H12N2O
 
2554 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0298
 
Celecoxib
 
C17H14F3N3O2S
 
2662 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0344
 
Cisplatin
 
Cl2H6N2Pt
 
5702198 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0360
 
Clofibrate
 
C12H15ClO3
 
2796 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0400
 
Cyclophosphamide
 
C7H15Cl2N2O2P
 
2907 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0476
 
Diclofenac
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0567
 
Enalapril
 
C20H28N2O5
 
5388962 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0601
 
Eslicarbazepine
 
C15H14N2O2
 
9881504 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0624
 
Etodolac
 
C17H21NO3
 
3308 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0639
 
Felbamate
 
C11H14N2O4
 
3331 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0671
 
Fludrocortisone
 
C21H29FO5
 
31378 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0786
 
Ibuprofen
 
C13H18O2
 
3672 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0790
 
Ifosfamide
 
C7H15Cl2N2O2P
 
3690 
Moderate    Inter Info   
[200], [2], [201], [202], [205], [221], [204], [229], [209], [212], [227], [228], [210], [213], [265], [266], [216], [215], [214], [208], [219], [211], [220], [224], [222], [234], [311], [235], [237], [332], [242], [333], [329], [334], [330], [351], [337], [247], [217], [249], [353], [257], [225], [226], [354], [355], [356], [357], [230], [264], [233], [260], [358], [268], [267], [359], [238], [239], [271], [360], [236], [361], [362], [363], [283], [284], [243], [364], [245], [248], [246], [287], [365], [296], [244], [291], [252], [298], [366], [301], [300], [256], [308], [312], [367], [261], [259], [317], [319], [320], [368], [321], [322], [274], [338], [339], [340], [277], [203], [206], [282], [207], [371], [285], [369], [288], [293], [290], [370], [295], [372], [350], [292], [294], [1], [373], [304], [352], [374], [375], [309], [310], [376], [377], [313], [315], [325], [328], [3], [336], [348], [344], [223], [231], [218], [232], [240], [241], [250], [251], [253], [254], [255], [258], [262], [263], [269], [270], [279], [272], [273], [275], [276], [278], [280], [281], [286], [289], [299], [297], [307], [302], [303], [305], [306], [314], [316], [318], [324], [323], [326], [327], [331], [335], [341], [342], [345], [346], [343], [347], [349]
D0800
 
Indomethacin
 
C19H16ClNO4
 
3715 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0882
 
Ketorolac
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0890
 
Lamotrigine
 
C9H7Cl2N5
 
3878 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D0988
 
Meclofenamic acid
 
C14H11Cl2NO2
 
4037 
Moderate    Inter Info   
[200], [202], [2]
D0995
 
Meloxicam
 
C14H13N3O4S2
 
54677470 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1035
 
Methyldopa
 
C10H13NO4
 
38853 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1097
 
Nabumetone
 
C15H16O2
 
4409 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1196
 
Oxaprozin
 
C18H15NO3
 
4614 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1198
 
Oxcarbazepine
 
C15H12N2O2
 
34312 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1274
 
Phenylbutazone
 
C19H20N2O2
 
4781 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1300
 
Piroxicam
 
C15H13N3O4S
 
54676228 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1421
 
Rofecoxib
 
C17H14O4S
 
5090 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1520
 
Sulindac
 
C20H17FO3S
 
1548887 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1606
 
Tolmetin
 
C15H15NO3
 
5509 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1668
 
Urea
 
CH4N2O
 
1176 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1674
 
Valdecoxib
 
C16H14N2O3S
 
119607 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1697
 
Vinblastine
 
C46H58N4O9
 
13342 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1698
 
Vincristine
 
C46H56N4O10
 
5978 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1699
 
Vincristine (liposome)
 
C46H56N4O10
 
5978 
Moderate    Inter Info   
[200], [202], [2]
D1700
 
Vinorelbine
 
C45H54N4O8
 
5311497 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Moderate    Inter Info   
[2], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255], [256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285], [286], [287], [288], [289], [290], [291], [292], [293], [294], [295], [296], [297], [298], [299], [300], [301], [302], [303], [304], [305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323], [324], [325], [326], [327], [328], [329], [330], [331], [332], [333], [334], [335], [3], [336], [337], [338], [339], [340], [341], [342], [343], [344], [345], [346], [347], [348], [349], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368], [369], [370], [371], [372], [1], [373], [374], [375], [376], [377]
   Increased risk of prolong QT interval Drug Num:  173
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0066
 
Amiodarone
 
C25H29I2NO3
 
2157 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]
D0067
 
Amisulpride
 
C17H27N3O4S
 
2159 
Major    Inter Info   
[14]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Major    Inter Info   
[1], [2], [3], [15]
D0149
 
Bedaquiline
 
C32H31BrN2O2
 
5388906 
Major    Inter Info   
[18]
D0170
 
Bepridil
 
C24H34N2O
 
2351 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]
D0230
 
Cabozantinib
 
C28H24FN3O5
 
25102847 
Major    Inter Info   
[3], [19]
D0302
 
Ceritinib
 
C28H36ClN5O3S
 
57379345 
Major    Inter Info   
[1], [2], [3], [20]
D0320
 
Chloroquine
 
C18H26ClN3
 
2719 
Major    Inter Info   
[21], [3], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39]
D0342
 
Cisapride
 
C23H29ClFN3O4
 
6917698 
Major    Inter Info   
[1], [2], [3], [40], [41], [42]
D0370
 
Clozapine
 
C18H19ClN4
 
135398737 
Major    Inter Info   
[1], [2], [3], [43], [13]
D0393
 
Crizotinib
 
C21H22Cl2FN5O
 
11626560 
Major    Inter Info   
[44]
D0508
 
Disopyramide
 
C21H29N3O
 
3114 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]
D0513
 
Dofetilide
 
C19H27N3O5S2
 
71329 
Major    Inter Info   
[1], [2], [3], [45]
D0514
 
Dolasetron
 
C19H20N2O3
 
3033818 
Major    Inter Info   
[1], [2], [3], [46]
D0534
 
Dronedarone
 
C31H44N2O5S
 
208898 
Major    Inter Info   
[1], [2], [3], [47]
D0535
 
Droperidol
 
C22H22FN3O2
 
3168 
Major    Inter Info   
[1], [2], [3], [48], [49], [13]
D0554
 
Efavirenz
 
C14H9ClF3NO2
 
64139 
Major    Inter Info   
[50]
D0712
 
Gatifloxacin
 
C19H22FN3O4
 
5379 
Major    Inter Info   
[53], [54], [55], [1], [2], [3], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75]
D0740
 
Grepafloxacin
 
C19H22FN3O3
 
72474 
Major    Inter Info   
[54], [1], [2], [3], [76], [77], [78]
D0749
 
Halofantrine
 
C26H30Cl2F3NO
 
37393 
Major    Inter Info   
[79], [1], [2], [3], [80], [81], [82], [83], [84]
D0750
 
Haloperidol
 
C21H23ClFNO2
 
3559 
Major    Inter Info   
[1], [2], [3], [85], [86], [87], [88], [89], [90], [13]
D0779
 
Hydroxychloroquine
 
C18H26ClN3O
 
3652 
Major    Inter Info   
[21], [3], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39]
D0787
 
Ibutilide
 
C20H36N2O3S
 
60753 
Major    Inter Info   
[1], [2], [3], [91]
D0791
 
Iloperidone
 
C24H27FN2O4
 
71360 
Major    Inter Info   
[1], [2], [3], [92], [13]
D0872
 
Ivosidenib
 
C28H22ClF3N6O3
 
71657455 
Major    Inter Info   
[95]
D0899
 
Lefamulin
 
C28H45NO5S
 
25185057 
Major    Inter Info   
[96]
D0909
 
Levacetylmethadol
 
C23H31NO2
 
15130 
Major    Inter Info   
[3], [97], [13]
D0960
 
Lumefantrine
 
C30H32Cl3NO
 
6437380 
Major    Inter Info   
[2], [3], [98]
D0965
 
Macimorelin
 
C26H30N6O3
 
9804938 
Major    Inter Info   
[99]
D1010
 
Mesoridazine
 
C21H26N2OS2
 
4078 
Major    Inter Info   
[1], [2], [3], [100], [13]
D1017
 
Methadone
 
C21H27NO
 
4095 
Major    Inter Info   
[1], [2], [3], [101], [102], [103], [104], [105], [106], [107], [108], [109], [110], [13]
D1063
 
Mifepristone
 
C29H35NO2
 
55245 
Major    Inter Info   
[1], [2], [3], [111]
D1092
 
Moxifloxacin
 
C21H24FN3O4
 
152946 
Major    Inter Info   
[53], [54], [55], [1], [2], [3], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75]
D1136
 
Nilotinib
 
C28H22F3N7O
 
644241 
Major    Inter Info   
[1], [2], [3], [112]
D1190
 
Osimertinib
 
C28H33N7O2
 
71496458 
Major    Inter Info   
[113]
D1221
 
Panobinostat
 
C21H23N3O2
 
6918837 
Major    Inter Info   
[115]
D1223
 
Papaverine
 
C20H21NO4
 
4680 
Major    Inter Info   
[116], [117], [118], [119], [120], [121], [122], [123]
D1230
 
Pasireotide
 
C58H66N10O9
 
9941444 
Major    Inter Info   
[1], [2], [3], [124]
D1292
 
Pimozide
 
C28H29F2N3O
 
16362 
Major    Inter Info   
[3], [48], [125], [13]
D1343
 
Procainamide
 
C13H21N3O
 
4913 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]
D1371
 
Quinidine
 
C20H24N2O2
 
441074 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]
D1398
 
Ribociclib
 
C23H30N8O
 
44631912 
Major    Inter Info   
[1], [2], [3], [48], [60], [126], [127], [13]
D1444
 
Saquinavir
 
C38H50N6O5
 
441243 
Major    Inter Info   
[128], [129], [1], [2], [3], [130], [131]
D1459
 
Selpercatinib
 
C29H31N7O3
 
134436906 
Major    Inter Info   
[3], [132]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]
D1499
 
Sparfloxacin
 
C19H22F2N4O3
 
60464 
Major    Inter Info   
[54], [1], [2], [3], [134], [135], [58], [60], [62], [136], [63], [64], [137], [66], [67], [68], [69], [138], [73], [78], [139]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Major    Inter Info   
[1], [2], [3], [140], [48], [141], [142], [143], [13]
D1612
 
Toremifene
 
C26H28ClNO
 
3005573 
Major    Inter Info   
[1], [2], [3], [144]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Major    Inter Info   
[1], [2], [3], [145]
D1726
 
Ziprasidone
 
C21H21ClN4OS
 
60854 
Major    Inter Info   
[1], [2], [3], [48], [146], [13]
D0737
 
Goserelin
 
C59H84N18O14
 
5311128 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0908
 
Leuprolide
 
C59H84N16O12
 
657181 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0003
 
Abarelix
 
C72H95ClN14O14
 
16131215 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0007
 
Abiraterone
 
C24H31NO
 
132971 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0036
 
Alfuzosin
 
C19H27N5O4
 
2092 
Moderate    Inter Info   
[1], [2], [3], [160], [13]
D0037
 
Alimemazine
 
C18H22N2S
 
5574 
Moderate    Inter Info   
[60], [127], [13]
D0068
 
Amitriptyline
 
C20H23N
 
2160 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0072
 
Amoxapine
 
C17H16ClN3O
 
2170 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0095
 
Apalutamide
 
C21H15F4N5O2S
 
24872560 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0097
 
Apomorphine
 
C17H17NO2
 
6005 
Moderate    Inter Info   
[1], [2], [3], [161], [13]
D0105
 
Aripiprazole
 
C23H27Cl2N3O2
 
60795 
Moderate    Inter Info   
[2], [3], [192], [193], [194], [195], [196], [197]
D0112
 
Asenapine
 
C17H16ClNO
 
3036780 
Moderate    Inter Info   
[1], [2], [3], [198], [13]
D0115
 
Astemizole
 
C28H31FN4O
 
2247 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0119
 
Atomoxetine
 
C17H21NO
 
54841 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0139
 
Azithromycin
 
C38H72N2O12
 
447043 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0180
 
Bicalutamide
 
C18H14F4N2O4S
 
2375 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0195
 
Bosutinib
 
C26H29Cl2N5O3
 
5328940 
Moderate    Inter Info   
[3], [199]
D0219
 
Buprenorphine
 
C29H41NO4
 
644073 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0336
 
Cilostazol
 
C20H27N5O2
 
2754 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0341
 
Ciprofloxacin
 
C17H18FN3O3
 
2764 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0349
 
Clarithromycin
 
C38H69NO13
 
84029 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0358
 
Clofazimine
 
C27H22Cl2N4
 
2794 
Moderate    Inter Info   
[378]
D0361
 
Clomipramine
 
C19H23ClN2
 
2801 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Moderate    Inter Info   
[379]
D0430
 
Daunorubicin (liposomal)
 
C27H29NO10
 
30323 
Moderate    Inter Info   
[60], [127], [13]
D0437
 
Degarelix
 
C82H103ClN18O16
 
16136245 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0446
 
Desipramine
 
C18H22N2
 
2995 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0467
 
Dextropropoxyphene
 
C22H29NO2
 
10100 
Moderate    Inter Info   
[60], [127], [13]
D0525
 
Doxepin
 
C19H21NO
 
667477 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0528
 
Doxorubicin
 
C27H29NO11
 
31703 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0529
 
Doxorubicin (liposomal)
 
C27H29NO11
 
31703 
Moderate    Inter Info   
[60], [127], [13]
D0569
 
Encorafenib
 
C22H27ClFN7O4S
 
50922675 
Moderate    Inter Info   
[385]
D0577
 
Entrectinib
 
C31H34F2N6O2
 
25141092 
Moderate    Inter Info   
[2], [3], [386]
D0578
 
Enzalutamide
 
C21H16F4N4O2S
 
15951529 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0584
 
Epirubicin
 
C27H29NO11
 
41867 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0594
 
Eribulin
 
C40H59NO11
 
11354606 
Moderate    Inter Info   
[1], [2], [3], [387]
D0597
 
Erythromycin
 
C37H67NO13
 
12560 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0632
 
Ezogabine
 
C16H18FN3O2
 
121892 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0636
 
Famotidine
 
C8H15N7O2S3
 
5702160 
Moderate    Inter Info   
[2], [3], [388]
D0664
 
Flecainide
 
C17H20F6N2O3
 
3356 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0667
 
Fluconazole
 
C13H12F2N6O
 
3365 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0682
 
Flutamide
 
C11H11F3N2O3
 
3397 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0694
 
Foscarnet
 
CH3O5P
 
3415 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0700
 
Fostemsavir
 
C25H26N7O8P
 
11319217 
Moderate    Inter Info   
[389]
D0716
 
Gemifloxacin
 
C18H20FN5O4
 
9571107 
Moderate    Inter Info   
[54], [62], [63], [68], [390]
D0720
 
Gilteritinib
 
C29H44N8O3
 
49803313 
Moderate    Inter Info   
[391]
D0725
 
Glasdegib
 
C21H22N6O
 
25166913 
Moderate    Inter Info   
[392]
D0738
 
Granisetron
 
C18H24N4O
 
5284566 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0751
 
Halothane
 
C2HBrClF3
 
3562 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0758
 
Histrelin
 
C66H86N18O12
 
25077993 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D0781
 
Hydroxyzine
 
C21H27ClN2O2
 
3658 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0788
 
Idarubicin
 
C26H27NO9
 
42890 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0795
 
Imipramine
 
C19H24N2
 
3696 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0894
 
Lapatinib
 
C29H26ClFN4O4S
 
208908 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0903
 
Lenvatinib
 
C21H19ClN4O4
 
9823820 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0919
 
Levofloxacin
 
C18H20FN3O4
 
149096 
Moderate    Inter Info   
[54], [1], [2], [3], [58], [59], [60], [394], [395], [63], [64], [396], [65], [397], [66], [67], [68], [69], [398], [399], [400], [73], [78]
D0937
 
Lisdexamfetamine
 
C15H25N3O
 
11597698 
Moderate    Inter Info   
[3]
D0940
 
Lithium carbonate
 
CLi2O3
 
11125 
Moderate    Inter Info   
[60], [127], [13]
D0942
 
Lofexidine
 
C11H12Cl2N2O
 
30668 
Moderate    Inter Info   
[1], [2], [3], [401], [13]
D0943
 
Lomefloxacin
 
C17H19F2N3O3
 
3948 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D0948
 
Lopinavir
 
C37H48N4O5
 
92727 
Moderate    Inter Info   
[1], [2], [402]
D0979
 
Maprotiline
 
C20H23N
 
4011 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1026
 
Methotrimeprazine
 
C19H24N2OS
 
72287 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1062
 
Midostaurin
 
C35H30N4O4
 
9829523 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1137
 
Nilutamide
 
C12H10F3N3O4
 
4493 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D1155
 
Norfloxacin
 
C16H18FN3O3
 
4539 
Moderate    Inter Info   
[54], [1], [2], [3], [58], [59], [60], [394], [395], [63], [64], [396], [65], [397], [66], [67], [68], [69], [398], [399], [400], [73], [78]
D1158
 
Nortriptyline
 
C19H21N
 
4543 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1165
 
Ofloxacin
 
C18H20FN3O4
 
4583 
Moderate    Inter Info   
[54], [1], [2], [3], [58], [59], [60], [394], [395], [63], [64], [396], [65], [397], [66], [67], [68], [69], [398], [399], [400], [73], [78]
D1166
 
Olanzapine
 
C17H20N4S
 
135398745 
Moderate    Inter Info   
[2], [3], [404]
D1169
 
Oliceridine
 
C22H30N2O2S
 
66553195 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1181
 
Ondansetron
 
C18H19N3O
 
4595 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1189
 
Osilodrostat
 
C13H10FN3
 
44139752 
Moderate    Inter Info   
[3], [405]
D1193
 
Oxaliplatin
 
C8H14N2O4Pt
 
9887053 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1210
 
Oxytocin
 
C43H66N12O12S2
 
439302 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1215
 
Paliperidone
 
C23H27FN4O3
 
115237 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1216
 
Palonosetron
 
C19H24N2O
 
6337614 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1232
 
Pazopanib
 
C21H23N7O2S
 
10113978 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1246
 
Pentamidine
 
C19H24N4O2
 
4735 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1254
 
Perflutren
 
C3F8
 
6432 
Moderate    Inter Info   
[406], [407]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1290
 
Pimavanserin
 
C25H34FN3O2
 
10071196 
Moderate    Inter Info   
[410]
D1302
 
Pitolisant
 
C17H26ClNO
 
9948102 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1315
 
Posaconazole
 
C37H42F2N8O4
 
468595 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1339
 
Primaquine
 
C15H21N3O
 
4908 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1342
 
Probucol
 
C31H48O2S2
 
4912 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1346
 
Prochlorperazine
 
C20H24ClN3S
 
4917 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1351
 
Promazine
 
C17H20N2S
 
4926 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1353
 
Propafenone
 
C21H27NO3
 
4932 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1356
 
Propofol
 
C12H18O
 
4943 
Moderate    Inter Info   
[411], [412], [413], [414], [415], [416], [417], [418], [419], [420]
D1361
 
Protriptyline
 
C19H21N
 
4976 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1368
 
Quetiapine
 
C21H25N3O2S
 
5002 
Moderate    Inter Info   
[1], [2], [3], [48], [421], [422], [423], [424], [13]
D1372
 
Quinine
 
C20H24N2O2
 
3034034 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1383
 
Ranolazine
 
C24H33N3O4
 
56959 
Moderate    Inter Info   
[425], [426]
D1388
 
Relugolix
 
C29H27F2N7O5S
 
10348973 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D1404
 
Rilpivirine
 
C22H18N6
 
6451164 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1413
 
Risperidone
 
C23H27FN4O2
 
5073 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1424
 
Romidepsin
 
C24H36N4O6S2
 
5352062 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1432
 
Rucaparib
 
C19H18FN3O
 
9931954 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1463
 
Sevoflurane
 
C4H3F7O
 
5206 
Moderate    Inter Info   
[1], [2], [3], [427]
D1491
 
Solifenacin
 
C23H26N2O2
 
154059 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1497
 
Sorafenib
 
C21H16ClF3N4O3
 
216239 
Moderate    Inter Info   
[1], [2], [3], [428]
D1522
 
Sunitinib
 
C22H27FN4O2
 
5329102 
Moderate    Inter Info   
[1], [2], [3], [429]
D1526
 
Tacrolimus
 
C44H69NO12
 
445643 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1533
 
Tamoxifen
 
C26H29NO
 
2733526 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1542
 
Telavancin
 
C80H106Cl2N11O27P
 
3081362 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1544
 
Telithromycin
 
C43H65N5O10
 
3002190 
Moderate    Inter Info   
[1], [2], [3], [430], [431], [432]
D1555
 
Terfenadine
 
C32H41NO2
 
5405 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1560
 
Tetrabenazine
 
C19H27NO3
 
6018 
Moderate    Inter Info   
[1], [2], [3], [433], [13]
D1596
 
Tizanidine
 
C9H8ClN5S
 
5487 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1616
 
Tramadol
 
C16H25NO2
 
33741 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1624
 
Trazodone
 
C19H22ClN5O
 
5533 
Moderate    Inter Info   
[437], [438], [192], [439], [440], [441], [13]
D1634
 
Triclabendazole
 
C14H9Cl3N2OS
 
50248 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1637
 
Trifluoperazine
 
C21H24F3N3S
 
5566 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1638
 
Triflupromazine
 
C18H19F3N2S
 
5568 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1647
 
Trimipramine
 
C20H26N2
 
5584 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1651
 
Triptorelin
 
C64H82N18O13
 
25074470 
Moderate    Inter Info   
[3], [147], [148], [149], [150], [151], [152], [153]
D1682
 
Vardenafil
 
C23H32N6O4S
 
135400189 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1706
 
Voriconazole
 
C16H14F3N5O
 
71616 
Moderate    Inter Info   
[1], [2], [3], [48], [60], [127], [13]
D1051
 
Metronidazole
 
C6H9N3O3
 
4173 
Minor    Inter Info   
[2], [443], [444], [445]
D1516
 
Sulfamethoxazole
 
C10H11N3O3S
 
5329 
Minor    Inter Info   
[1], [2], [3], [446], [447], [448], [449]
   Increased risk of ventricular arrhythmias Drug Num:  28
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0107
 
Arsenic trioxide
 
As2O3
 
14888 
Major    Inter Info   
[16], [17]
D0661
 
Fingolimod
 
C19H33NO2
 
107970 
Major    Inter Info   
[1], [2], [3], [51], [52]
D0868
 
Ivabradine
 
C27H36N2O5
 
132999 
Major    Inter Info   
[3], [93], [94]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Major    Inter Info   
[114]
D1474
 
Siponimod
 
C29H35F3N2O3
 
44599207 
Major    Inter Info   
[2], [133]
D0025
 
Adenosine
 
C10H13N5O4
 
60961 
Moderate    Inter Info   
[1], [154], [2], [3], [155], [156], [157], [40], [158], [159]
D0103
 
Arformoterol
 
C19H24N2O4
 
3083544 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D0516
 
Donepezil
 
C24H29NO3
 
3152 
Moderate    Inter Info   
[1], [2], [3], [382], [383], [384]
D0691
 
Formoterol
 
C19H24N2O4
 
3410 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D0707
 
Galantamine
 
C17H21NO3
 
9651 
Moderate    Inter Info   
[1], [2], [3], [382], [383], [384]
D0797
 
Indacaterol
 
C24H28N2O3
 
6918554 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D0854
 
Isoetharine
 
C13H21NO3
 
3762 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D0859
 
Isoprenaline
 
C11H17NO3
 
3779 
Moderate    Inter Info   
[175], [185], [188]
D0924
 
Levosalbutamol
 
C13H21NO3
 
123600 
Moderate    Inter Info   
[175], [185], [188]
D1171
 
Olodaterol
 
C21H26N2O5
 
11504295 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D1185
 
Orciprenaline
 
C11H17NO3
 
4086 
Moderate    Inter Info   
[175], [185], [188]
D1287
 
Picosulfuric acid
 
C18H15NO8S2
 
5243 
Moderate    Inter Info   
[3], [408], [409]
D1298
 
Pirbuterol
 
C12H20N2O3
 
4845 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D1308
 
Polyethylene glycol (3350 with electrolytes)
 
C2H6O2
 
174 
Moderate    Inter Info   
[3], [408], [409]
D1414
 
Ritodrine
 
C17H21NO3
 
33572 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D1418
 
Rivastigmine
 
C14H22N2O2
 
77991 
Moderate    Inter Info   
[1], [2], [3], [382], [383], [384]
D1438
 
Salbutamol
 
C13H21NO3
 
2083 
Moderate    Inter Info   
[175], [185], [188]
D1440
 
Salmeterol
 
C25H37NO4
 
5152 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D1488
 
Sodium sulfate
 
Na2O4S
 
24436 
Moderate    Inter Info   
[3], [408], [409]
D1525
 
Tacrine
 
C13H14N2
 
1935 
Moderate    Inter Info   
[1], [2], [3], [382], [383], [384]
D1554
 
Terbutaline
 
C12H19NO3
 
5403 
Moderate    Inter Info   
[162], [163], [164], [165], [166], [167], [168], [169], [170], [171], [172], [173], [174], [175], [176], [177], [178], [179], [180], [181], [182], [183], [184], [185], [186], [187], [188], [189], [190], [191]
D1569
 
Thalidomide
 
C13H10N2O4
 
5426 
Moderate    Inter Info   
[2], [3], [434]
D1695
 
Vilanterol
 
C24H33Cl2NO5
 
10184665 
Moderate    Inter Info   
[175], [185], [188]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0441
 
Demeclocycline
 
C21H21ClN2O8
 
54680690 
Moderate    Inter Info   
[2], [3], [294]
D0753
 
Heparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[2], [3], [294]
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114 Product Information. Zeposia (ozanimod). Celgene Corporation, Summit, NJ.
115 Product Information. Farydak (panobinostat). Novartis Pharmaceuticals, East Hanover, NJ.
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132 Product Information. Retevmo (selpercatinib). Lilly, Eli and Company, Indianapolis, IN.
133 Product Information. Mayzent (siponimod). Novartis Pharmaceuticals, East Hanover, NJ.
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146 Product Information. Geodon (ziprasidone). Pfizer US Pharmaceuticals, New York, NY.
147 Product Information. Eligard (leuprolide). Sanofi Winthrop Pharmaceuticals, New York, NY.
148 Product Information. Firmagon (degarelix). Ferring Pharmaceuticals Inc, Tarrytown, NY.
149 Product Information. Lupron (leuprolide). TAP Pharmaceuticals Inc, Deerfield, IL.
150 Product Information. Plenaxis (abarelix). Praecis Pharmaceuticals Inc, Waltham, MA.
151 Product Information. Trelstar (triptorelin) Pharmacia and Upjohn, Kalamazoo, MI.
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153 Product Information. Zoladex (goserelin). Zeneca Pharmaceuticals, Wilmington, DE.
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177 Product Information. Brovana (arformoterol). Sepracor Inc, Marlborough, MA.
178 Product Information. Foradil (formoterol) Novartis Pharmaceuticals, East Hanover, NJ.
179 Product Information. Maxair (pirbuterol). 3M Pharmaceuticals, St. Paul, MN.
180 Product Information. Proventil (albuterol). Schering Laboratories, Kenilworth, NJ.
181 Product Information. Severent (salmeterol). Glaxo Wellcome, Research Triangle Park, NC.
182 Product Information. Striverdi Respimat (olodaterol). Boehringer Ingelheim, Ridgefield, CT.
183 Product Information. Xopenex (levalbuterol). Sepracor, Marlborough, MA.
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356 Product Information. Pitressin (vasopressin). Parke-Davis, Morris Plains, NJ.
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369 Product Information. Stimate (desmopressin). Forest Pharmaceuticals, St. Louis, MO.
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378 Product Information. Lamprene (clofazimine). Novartis Pharmaceuticals, East Hanover, NJ.
379 Product Information. Sprycel (dasatinib). Bristol-Myers Squibb, Princeton, NJ.
380 Product Information. Austedo (deutetrabenazine). Teva Pharmaceuticals USA, North Wales, PA.
381 Russell JA, Walley KR, Singer J, et al. "Vasopressin versus norepinephrine infusion in patients with septic shock." N Engl J Med 358 (2008): 877-87
382 Product Information. Aricept (donepezil). Pfizer US Pharmaceuticals, New York, NY.
383 Product Information. Exelon (rivastigmine) Novartis Pharmaceuticals, East Hanover, NJ.
384 Product Information. Razadyne (galantamine). Johnson and Johnson Medical Inc, Arlington, TX.
385 Product Information. Braftovi (encorafenib). Array BioPharma Inc., Boulder, CO.
386 Product Information. Rozlytrek (entrectinib). Genentech, South San Francisco, CA.
387 Product Information. Halaven (eribulin). Eisai Inc, Teaneck, NJ.
388 Product Information. Pepcid (famotidine). Merck & Co, Inc, West Point, PA.
389 Product Information. Rukobia (fostemsavir). ViiV Healthcare, Research Triangle Park, NC.
390 Product Information. Factive (gemifloxacin). GeneSoft Inc, San Francisco, CA.
391 Product Information. Xospata (gilteritinib). Astellas Pharma US, Inc, Deerfield, IL.
392 Product Information. Daurismo (glasdegib). Pfizer U.S. Pharmaceuticals Group, New York, NY.
393 Product Information. Ketalar (ketamine). JHP Pharmaceuticals, Saddle River, NJ.
394 Iannini PB, Doddamani S, Byazrova E, Curciumaru I, Kramer H "Risk of torsades de pointes with non-cardiac drugs. Prolongation of QT interval is probably a class effect of fluoroquinolones." Br Med J 322 (2001): 46-7. [PMID: 11141163]
395 Kahn JB "Latest industry information on the safety profile of levofloxacin in the US." Chemotherapy 47 Suppl 3 (2001): 32-7. [PMID: 11549787]
396 Makaryus AN, Byrns K, Makaryus MN, Natarajan U, Singer C, Goldner B "Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event?" South Med J 99 (2006): 52-6. [PMID: 16466123]
397 Nykamp DL, Blackmon CL, Schmidt PE, Roberson AG "QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine." Ann Pharmacother 39 (2005): 543-6. [PMID: 15687478]
398 Product Information. Floxin (ofloxacin). Ortho Pharmaceutical Corporation, Raritan, NJ.
399 Product Information. Levaquin (levofloxacin). Ortho Pharmaceutical Corporation, Raritan, NJ.
400 Samaha FF "QTC interval prolongation and polymorphic ventricular tachycardia in association with levofloxacin." Am J Med 107 (1999): 528-9. [PMID: 10569314]
401 Product Information. Lucemyra (lofexidine). US WorldMeds LLC, Louisville , KY.
402 Product Information. Kaletra (lopinavir-ritonavir) Abbott Pharmaceutical, Abbott Park, IL.
403 Canadian Pharmacists Association "e-CPS."
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406 Product Information. Definity (perflutren). Lantheus Medical Imaging Inc, North Billerica, MA.
407 Product Information. Optison (perflutren). Mallinckrodt Medical Inc, St. Louis, MO.
408 Product Information. Suclear (polyethylene glycol 3350 with electrolytes). Braintree Laboratories, Braintree, MA.
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411 Hanci V, Aydin M, Yurtlu BS, et.al "Anesthesia induction with sevoflurane and propofol: evaluation of P-wave dispersion, QT and corrected QT intervals." Kaohsiung J Med Sci 26 (2010): 470-7. [PMID: 20837343]
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413 Kleinsasser A, Kuenszberg E, Loeckinger A, et.al "Sevoflurane, but not propofol, significantly prolongs the Q-T interval." Anesth Analg 90 (2000): 25-7. [PMID: 10624970]
414 Kleinsasser A, Loeckinger A, Lindner KH, Keller C, Boehler M, Puehringer F "Reversing sevoflurane-associated Q-Tc prolongation by changing to propofol." Anaesthesia 56 (2001): 248-50. [PMID: 11251432]
415 Paventi S, Santevecchi A, Ranieri R "Effects of sevoflurane versus propofol on QT interval." Minerva Anestesiol 67 (2001): 637-40. [PMID: 11731753]
416 Scalese MJ, Herring HR, Rathburn RC, Skrepnek GH, Ripley TL "Propofol-associated QTc prolongation." Ther Adv Drug Saf 7 (2016): 68-78. [PMID: 27298717]
417 Staikou C, Stamelos M, Stavroulakis E "Impact of anaesthetic drugs and adjuvants on ECG markers of torsadogenicity." Br J Anaesth 112 (2014): 217-30. [PMID: 24305646]
418 Toyoda T, Terao Y, Oji M, Okada M, Fukusaki M, Sumikawa K "The interaction of antiemetic dose of droperidol with propofol on QT interval during anesthetic induction." J Anesth 27 (2013): 885-9. [PMID: 23660990]
419 Whyte SD, Booker PD, Buckley DG "The Effects of Propofol and Sevoflurane on the QT Interval and Transmural Dispersion of Repolarization in Children." Anesth Analg 100 (2005): 71-77. [PMID: 15616054]
420 Wutzler A, De Asmundis C, Matsuda H, et.al "Effects of propofol on ventricular repolarization and incidence of malignant arrhythmias in adults." J Electrocardiol 51 (2018): 170-4. [PMID: 29174097]
421 Product Information. Seroquel (quetiapine). Zeneca Pharmaceuticals, Wilmington, DE.
422 Sala M, Vicentini A, Brambilla P, et al. "QT interval prolongation related to psychoactive drug treatment: a comparison of monotherapy versus polytherapy." Ann Gen Psychiatry 4 (2005): 1. [PMID: 15845138]
423 Vieweg WV "New generation antipsychotic drugs and QTc interval prolongation." Prim Care Companion J Clin Psychiatry 5 (2003): 205-15. [PMID: 15213787]
424 Vieweg WV, Schneider RK, Wood MA "Torsade de pointes in a patient with complex medical and psychiatric conditions receiving low-dose quetiapine." Acta Psychiatr Scand 112 (2005): 318-22. [PMID: 16156840]
425 European Medicines Agency "CHMP Assessment Report for Latixa. International nonproprietary name: ranolazine.".
426 Product Information. Ranexa (ranolazine). Calmoseptine Inc, Huntington Beach, CA.
427 Product Information. Ultane (sevoflurane). Abbott Pharmaceutical, Abbott Park, IL.
428 Product Information. Nexavar (sorafenib). Bayer Pharmaceutical Inc, West Haven, CT.
429 Product Information. Sutent (sunitinib). Pfizer U.S. Pharmaceuticals Group, New York, NY.
430 Demolis JL, Vacheron F, Cardus S, Funck-Brentano C "Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects." Clin Pharmacol Ther 73 (2003): 242-52. [PMID: 12621389]
431 Product Information. Ketek (telithromycin). Aventis Pharmaceuticals, Bridgewater, NJ.
432 European Agency for the Evaluation of Medicinal Products. Committee for Proprietary Medicinal Products "European Public Assessment Report Ketek (telithromycin) (Rev. 2) ".
433 Product Information. Xenazine (tetrabenazine). Prestwick Pharmaceuticals Inc, Washington DC, VA.
434 Product Information. Thalomid (thalidomide). Celgene Corporation, Warren, NJ.
435 Nuclear Pharmacy Website. University of Arkansas for Medical Sciences. College of Pharmacy "Drug - Radiopharmaceutical Interactions. Available from: URL: http://nuclearpharmacy.uams.edu/nicki.html#tl.".
436 Product Information. Thallous Chloride Tl 201 (thallous chloride Tl-201). GE Healthcare, Princeton, NJ.
437 Antonelli D, Atar S, Freedberg NA, Rosenfeld T "Torsade de pointes in patients on chronic amiodarone treatment: contributing factors and drug interactions." Isr Med Assoc J 7 (2005): 163-5. [PMID: 15792261]
438 Dattilo PB, Nordin C "Prolonged QT associated with an overdose of trazodone." J Clin Psychiatry 68 (2007): 1309-10. [PMID: 17854263]
439 Levenson JL "Prolonged QT interval after trazodone overdose." Am J Psychiatry 156 (1999): 969-70. [PMID: 10360146]
440 Mazur A, Strasberg B, Kusniec J, Sclarovsky S "QT prolongation and polymorphous ventricular tachycardia associated with trasodone-amiodarone combination." Int J Cardiol 52 (1995): 27-9. [PMID: 8707432]
441 Product Information. Oleptro (traZODone). Labopharm Inc, Laval, AL.
442 Product Information. Ingrezza (valbenazine). Neurocrine Biosciences, Inc., San Diego, CA.
443 Kounas SP, Letsas KP, Sideris A, Efraimidis M, Kardaras F "QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone." Pacing Clin Electrophysiol 28 (2005): 472-3. [PMID: 15869686]
444 Product Information. Flagyl (metronidazole). Searle, Skokie, IL.
445 Product Information. Pylera (bismuth subcitrate potassium/metronidazo/TCN). Aptalis Pharma, Birmingham, AL.
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