Details of Drug

Drug General Information (ID: D1601)
Drug Name	Tolazamide
Drug Type	Small molecule
Drug Synonymous	Diabewas; Norglycin; Tolamide; Tolanase; Tolazamida; Tolazamidum; Tolazolamide; Tolinase; Pharmacia Brand of Tolazamide; T 2408; U 17835; Tolazamida [INN-Spanish]; Tolazamidum [INN-Latin]; Tolinase (TN); U-17835; Tolazamide (JP15/USP/INN); Tolazamide [USAN:INN:BAN:JAN]; N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea; N-[(azepan-1-ylamino)carbonyl]-4-methylbenzenesulfonamide; N-(((hexahydro-1H-azepin-1-yl)amino)carbonyl)-4-methylbenzenesulfonamide; Benzenesulfonamide, {N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-}; N-(((Hexahydro-1H-azepin-1-yl)-amino)carbonyl)-4-methylbenzenesulfonamide; 1-(((((4-Methylphenyl)sulfonyl)amino)carbonyl)amino)azepane; 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea; 1-(Hexahydro-1H-azepin-1-yl)-3-(p-toluenesulfonyl)urea; 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; 1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea; 3-azepan-1-yl-1-(4-methylphenyl)sulfonyl-urea; 4-(p-Tolylsulfonyl)-1,1-hexamethylene; 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide; 59866P Click to Show/Hide
Disease Class	5A2Y: Acute diabete complication
Therapeutic Class	Antidiabetic Agents
Structure
Structure	3D Structure		2D Structure
Formula	C14H21N3O3S
InChI	1S/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18)
InChIKey	OUDSBRTVNLOZBN-UHFFFAOYSA-N
Canonical SMILES	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCCCC2
External Link
	Pubchem ID	5503
	CAS Number	1156-19-0
	CHEBI ID	9613
	TTD ID	D09FJB
	INTEDE ID	DR1611

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM003 Affected organization distribution AM004 Affected intra/extra-hepatic metabolism AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM003 Complex formation BM004 Adsorption BM005 Altered gastric pH BM013 Competitive binding of plasma proteins BM017 CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM025 Decreased metabolism (Unspecific) BM029 Altered urine pH BM032 Decreased renal excretion (Unspecific) BM064 Increased risk of hypoglycemia BM075 Increased risk of photosensitivity reactions BM086 Antagonize the effect of antidiabetic agents BM089 Antagonize the effect of antihypertensive agents
Relation Graph

Full list of drugs interacting with Tolazamide
Affected gastrointestinal absorption
	Complex formation					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0329		Cholestyramine	C27H47ClN2	137699107	Moderate		Inter Info	[200], [230]
D0381		Colesevelam	C31H67Cl3N4O	160051	Moderate		Inter Info	[164], [235]
	Adsorption					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0021		Activated charcoal	C	5462310	Moderate		Inter Info	[189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213]
	Altered gastric pH					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0337		Cimetidine	C10H16N6S	2756	Moderate		Inter Info	[139], [140], [141], [142]
D1151		Nizatidine	C12H21N5O2S2	3033637	Moderate		Inter Info	[139], [140], [141], [142]
D0236		Calcium carbonate	CCaO3	10112	Moderate		Inter Info	[227], [100], [17]
D0636		Famotidine	C8H15N7O2S3	5702160	Moderate		Inter Info	[139], [140], [141], [142]
D0967		Magaldrate	AlHMgO5S+2	3086011	Moderate		Inter Info	[227], [100], [17]
D0968		Magnesium carbonate	CMgO3	11029	Moderate		Inter Info	[227], [100], [17]
D0973		Magnesium hydroxide	H2MgO2	14791	Moderate		Inter Info	[247], [248], [249], [227], [100], [16], [17]
D0974		Magnesium oxide	MgO	14792	Moderate		Inter Info	[247], [248], [249], [227], [100], [16], [17]
D1381		Ranitidine	C13H22N4O3S	3001055	Moderate		Inter Info	[139], [140], [141], [142]
D1382		Ranitidine (bismuth citrate)	C13H22N4O3S	3001055	Moderate		Inter Info	[139], [140], [141]
D1480		Sodium bicarbonate	CHNaO3	516892	Moderate		Inter Info	[247], [248], [249], [227], [100], [16], [17]
Affected organization distribution
	Competitive binding of plasma proteins					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[137], [138]
D1142		Nitazoxanide	C12H9N3O5S	41684	Moderate		Inter Info	[163]
D0349		Clarithromycin	C38H69NO13	84029	Moderate		Inter Info	[234]
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 12
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0667		Fluconazole	C13H12F2N6O	3365	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28]
D1057		Miconazole	C18H14Cl4N2O	4189	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28]
D1706		Voriconazole	C16H14F3N5O	71616	Major		Inter Info	[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28]
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[146], [147]
D1063		Mifepristone	C29H35NO2	55245	Moderate		Inter Info	[162]
D1112		Nateglinide	C19H27NO3	5311309	Moderate		Inter Info	[105]
D1143		Nitisinone	C14H10F3NO5	115355	Moderate		Inter Info	[164], [158], [165]
D0628		Etravirine	C20H15BrN6O	193962	Moderate		Inter Info	[238]
D0869		Ivacaftor	C24H28N2O3	16220172	Moderate		Inter Info	[239], [240], [241], [242]
D0900		Leflunomide	C12H9F3N2O2	3899	Moderate		Inter Info	[243], [244]
D0603		Esomeprazole	C17H19N3O3S	9568614	Minor		Inter Info	[260], [261], [262], [263]
D1179		Omeprazole	C17H19N3O3S	4594	Minor		Inter Info	[260], [261], [262], [263]
	CYP450 enzyme induction					Drug Num: 8
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0194		Bosentan	C27H29N5O6S	104865	Moderate		Inter Info	[136]
D1399		Rifabutin	C46H62N4O11	135398743	Moderate		Inter Info	[181], [182], [183], [184], [185], [186], [187], [188]
D0044		Alpelisib	C19H22F3N5O2S	56649450	Moderate		Inter Info	[223], [224], [225]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[158], [133], [236]
D0906		Letermovir	C29H28F4N4O4	45138674	Moderate		Inter Info	[245]
D0953		Lorlatinib	C21H19FN6O2	71731823	Moderate		Inter Info	[158], [133], [246]
D1400		Rifampicin	C43H58N4O12	135398735	Moderate		Inter Info	[181], [182], [183]
D1401		Rifapentine	C47H64N4O12	135403821	Moderate		Inter Info	[251], [252]
	Decreased metabolism (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[175], [13], [121]
D1518		Sulfinpyrazone	C23H20N2O3S	5342	Moderate		Inter Info	[175], [13], [121]
D1035		Methyldopa	C10H13NO4	38853	Minor		Inter Info	[274]
Affected excretion pathways
	Altered urine pH					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0886		Lactic acid	C3H6O3	612	Minor		Inter Info	[269], [270], [170]
D1319		Potassium citrate	C6H5K3O7	13344	Minor		Inter Info	[269], [270]
D1478		Sodium acetate	C2H3NaO2	517045	Minor		Inter Info	[269], [270]
D1483		Sodium citrate	C6H5Na3O7	6224	Minor		Inter Info	[269], [270]
D1654		Tromethamine	C4H11NO3	6503	Minor		Inter Info	[269], [270], [170]
Pharmacodynamic additive effects
	Increased risk of hypoglycemia					Drug Num: 150
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0072		Amoxapine	C17H16ClN3O	2170	Moderate		Inter Info	[36], [37], [38]
D0156		Benazepril	C24H28N2O5	5362124	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0178		Bexarotene	C24H28O2	82146	Moderate		Inter Info	[133], [134], [135]
D0298		Celecoxib	C17H14F3N3O2S	2662	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0345		Citalopram	C20H21FN2O	2771	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0360		Clofibrate	C12H15ClO3	2796	Moderate		Inter Info	[51], [66], [124]
D0363		Clonidine	C9H9Cl2N3	2803	Moderate		Inter Info	[143], [144], [145]
D0400		Cyclophosphamide	C7H15Cl2N2O2P	2907	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0467		Dextropropoxyphene	C22H29NO2	10100	Moderate		Inter Info	[51], [66], [124]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0508		Disopyramide	C21H29N3O	3114	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0567		Enalapril	C20H28N2O5	5388962	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1731		Ethionamide	C8H10N2S	2761171	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0624		Etodolac	C17H21NO3	3308	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0641		Fenfluramine	C12H16F3N	3337	Moderate		Inter Info	[148], [149], [150]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0676		Fluoxetine	C17H18F3NO	3386	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0743		Guanadrel	C10H19N3O2	38521	Moderate		Inter Info	[151], [152], [153]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[36], [37], [38]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0811		Insulin glargine	C267H404N72O78S6	118984454	Moderate		Inter Info	[133], [14], [154]
D0813		Insulin human	C257H383N65O77S6	118984375	Moderate		Inter Info	[133], [14], [154]
D0814		Insulin human (inhalation, rapid acting)	C257H383N65O77S6	118984375	Moderate		Inter Info	[133], [14], [154]
D0815		Insulin human (isophane)	C257H383N65O77S6	118984375	Moderate		Inter Info	[133], [14], [154]
D0816		Insulin human (regular)	C257H383N65O77S6	118984375	Moderate		Inter Info	[133], [14], [154]
D0817		Insulin human (zinc extended)	C257H383N65O77S6	118984375	Moderate		Inter Info	[133], [14], [154]
D0818		Insulin human (zinc)	C257H383N65O77S6	118984375	Moderate		Inter Info	[133], [14], [154]
D0819		Insulin lispro	C257H389N65O77S6	16132438	Moderate		Inter Info	[133], [14], [154]
D0820		Insulin lispro (protamine)	C257H389N65O77S6	16132438	Moderate		Inter Info	[133], [14], [154]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0938		Lisinopril	C21H31N3O5	5362119	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0981		Mazindol	C16H13ClN2O	4020	Moderate		Inter Info	[148], [149], [150]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1015		Metformin	C4H11N5	4091	Moderate		Inter Info	[155], [156], [157]
D1082		Moexipril	C27H34N2O7	91270	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1158		Nortriptyline	C19H21N	4543	Moderate		Inter Info	[36], [37], [38]
D1195		Oxandrolone	C19H30O3	5878	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1229		Paroxetine	C19H20FNO3	43815	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1862		Pegvisomant	NA	NA	Moderate		Inter Info	[169], [170], [171]
D1251		Pentoxifylline	C13H18N4O3	4740	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1256		Perindopril	C19H32N2O5	107807	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1263		Phenelzine	C8H12N2	3675	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1300		Piroxicam	C15H13N3O4S	54676228	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1361		Protriptyline	C19H21N	4976	Moderate		Inter Info	[36], [37], [38]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1379		Ramipril	C23H32N2O5	5362129	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1393		Reserpine	C33H40N2O9	5770	Moderate		Inter Info	[151], [152], [153]
D1421		Rofecoxib	C17H14O4S	5090	Moderate		Inter Info	[51], [66], [124]
D1513		Sulfadiazine	C10H10N4O2S	5215	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Moderate		Inter Info	[51], [66], [124]
D1517		Sulfasalazine	C18H14N4O5S	5339	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1519		Sulfisoxazole	C11H13N3O3S	5344	Moderate		Inter Info	[51], [66], [124]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1558		Testosterone	C19H28O2	6013	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1559		Testosterone (topical)	C19H28O2	6013	Moderate		Inter Info	[51], [66], [124]
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[51], [66], [124]
D0029		Albiglutide	C148H224N40O45	145994868	Moderate		Inter Info	[214], [215], [216]
D1736		Aloe Vera Leaf	C15H10O5	10207	Moderate		Inter Info	[217], [218], [219]
D0042		Alogliptin	C18H21N5O2	11450633	Moderate		Inter Info	[220], [221], [222]
D0145		Balsalazide	C17H15N3O6	54585	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[148], [149], [150]
D0187		Bismuth subsalicylate	C7H6BiO4	16682734	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[51], [66], [124]
D0245		Canagliflozin	C24H25FO5S	24812758	Moderate		Inter Info	[228], [155], [229]
D0254		Captopril	C9H15NO3S	44093	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0331		Choline salicylate	C12H19NO4	54686350	Moderate		Inter Info	[51], [66], [124]
D1759		Chromic chloride	NA	NA	Moderate		Inter Info	[231], [232], [233]
D0332		Chromium picolinate	C18H12CrN3O6	151932	Moderate		Inter Info	[231], [232], [233]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[36], [37], [38]
D0418		Dapagliflozin	C21H25ClO6	9887712	Moderate		Inter Info	[228], [155], [229]
D0444		Deserpidine	C32H38N2O8	8550	Moderate		Inter Info	[151], [152], [153]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[36], [37], [38]
D0457		Dexfenfluramine	C12H16F3N	66265	Moderate		Inter Info	[148], [149], [150]
D0486		Diethylpropion	C13H19NO	7029	Moderate		Inter Info	[148], [149], [150]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0525		Doxepin	C19H21NO	667477	Moderate		Inter Info	[36], [37], [38]
D0526		Doxepin (topical)	C19H21NO	667477	Moderate		Inter Info	[36], [37], [38]
D1779		Dulaglutide	NA	NA	Moderate		Inter Info	[214], [215], [237]
D0565		Empagliflozin	C23H27ClO7	11949646	Moderate		Inter Info	[228], [155], [229]
D1782		Ertugliflozin	C22H25ClO7	44814423	Moderate		Inter Info	[228], [155], [229]
D0599		Escitalopram	C20H21FN2O	146570	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0642		Fenofibrate	C20H21ClO4	3339	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0643		Fenofibric acid	C17H15ClO4	64929	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0677		Fluoxymesterone	C20H29FO3	6446	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0715		Gemfibrozil	C15H22O3	3463	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0723		Ginseng	C42H66O17	420552	Moderate		Inter Info	[51], [66], [124]
D0744		Guanethidine	C10H22N4	3518	Moderate		Inter Info	[151], [152], [153]
D0753		Heparin	C26H42N2O37S5	772	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0790		Ifosfamide	C7H15Cl2N2O2P	3690	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0807		Insulin aspart (aspart protamine)	C256H381N65O79S6	118984445	Moderate		Inter Info	[133], [14], [154]
D0808		Insulin aspart (aspart)	C256H381N65O79S6	118984445	Moderate		Inter Info	[133], [14], [154]
D0809		Insulin degludec	C274H411N65O81S6	118984462	Moderate		Inter Info	[133], [14], [154]
D0810		Insulin detemir	C267H402N64O76S6	16137271	Moderate		Inter Info	[133], [14], [154]
D0812		Insulin glulisine	C258H384N64O78S6	16136701	Moderate		Inter Info	[133], [14], [154]
D0853		Isocarboxazid	C12H13N3O2	3759	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0930		Linagliptin	C25H28N8O2	10096344	Moderate		Inter Info	[220], [221], [222]
D0936		Liraglutide	C172H265N43O51	16134956	Moderate		Inter Info	[214], [215], [216]
D0941		Lixisenatide	C215H347N61O65S	90472060	Moderate		Inter Info	[214], [215], [216]
D0952		Lorcaserin	C11H14ClN	11658860	Moderate		Inter Info	[148], [149], [150]
D0984		Mecasermin	NA	NA	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D0985		Mecasermin rinfabate	NA	NA	Moderate		Inter Info	[51], [66], [124]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[51], [66], [124]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[148], [149], [150]
D1042		Methyltestosterone	C20H30O2	6010	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1050		Metreleptin	NA	NA	Moderate		Inter Info	[101], [250], [170]
D1173		Olsalazine	C14H10N2O6	22419	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1187		Orlistat	C29H53NO5	3034010	Moderate		Inter Info	[148], [149], [150]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1207		Oxymetholone	C21H32O3	5281034	Moderate		Inter Info	[51], [66], [124]
D1262		Phendimetrazine	C12H17NO	30487	Moderate		Inter Info	[148], [149], [150]
D1272		Phenyl salicylate	C13H10O3	8361	Moderate		Inter Info	[51], [66], [124]
D1326		Pramlintide	C171H267N51O53S2	70691388	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1341		Probenecid	C13H19NO4S	4911	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1369		Quinapril	C25H30N2O5	54892	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1385		Rasagiline	C12H13N	3052776	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1437		Safinamide	C17H19FN2O2	131682	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[51], [66], [124]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1449		Saxagliptin	C18H25N3O2	11243969	Moderate		Inter Info	[220], [221], [222]
D1455		Selegiline	C13H17N	26757	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1887		Semaglutide	C187H291N45O59	56843331	Moderate		Inter Info	[214], [215], [237]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[148], [149], [150]
D1477		Sitagliptin	C16H15F6N5O	4369359	Moderate		Inter Info	[220], [221], [222]
D1503		Stanozolol	C21H32N2O	25249	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1514		Sulfadoxine	C12H14N4O4S	17134	Moderate		Inter Info	[51], [66], [124]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Moderate		Inter Info	[51], [66], [124]
D1661		Turmeric	C21H20O6	969516	Moderate		Inter Info	[253], [254], [255]
D1696		Vilazodone	C26H27N5O2	6918314	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1708		Vortioxetine	C18H22N2S	9966051	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1618		Trandolapril	C24H34N2O5	5484727	Moderate		Inter Info	[4], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [10], [91], [92], [93], [94], [95], [96], [97], [13], [98], [14], [99], [100], [101], [34], [16], [102], [17], [103], [104], [105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123], [124], [125], [126], [127], [128], [129], [130], [131], [132]
D1620		Tranylcypromine	C9H11N	19493	Moderate		Inter Info	[51], [66], [124]
D1647		Trimipramine	C20H26N2	5584	Moderate		Inter Info	[36], [37], [38]
D1674		Valdecoxib	C16H14N2O3S	119607	Moderate		Inter Info	[51], [66], [124]
D1836		Lipoic acid	C8H14O2S2	6112	Minor		Inter Info	[170], [264], [265]
D0711		Garlic	NA	NA	Minor		Inter Info	[266], [267], [268]
D1034		Methylcellulose	C29H54O16	44263857	Minor		Inter Info	[271], [272], [273]
D1303		Plantago seed	NA	NA	Minor		Inter Info	[271], [272], [273]
	Increased risk of photosensitivity reactions					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0062		Aminolevulinic acid	C5H9NO3	137	Major		Inter Info	[29], [30]
D1028		Methoxsalen	C12H8O4	4114	Moderate		Inter Info	[158], [159], [29], [160], [161]
D1314		Porfimer sodium	C68H74N8O11	135577896	Moderate		Inter Info	[179], [133], [180]
D0063		Aminolevulinic acid (topical)	C5H9NO3	137	Moderate		Inter Info	[158], [133], [226]
D1033		Methyl aminolevulinate (topical)	C6H11NO3	157922	Moderate		Inter Info	[158], [133], [226]
D1691		Verteporfin	C82H84N8O16	11980904	Moderate		Inter Info	[133], [159], [29], [256]
Pharmacodynamic antagonistic effects
	Antagonize the effect of antidiabetic agents					Drug Num: 168
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0340		Cinoxacin	C12H10N2O5	2762	Major		Inter Info	[1], [2], [3]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Major		Inter Info	[1], [2], [3]
D0573		Enoxacin	C15H17FN4O3	3229	Major		Inter Info	[1], [2], [3]
D0740		Grepafloxacin	C19H22FN3O3	72474	Major		Inter Info	[1], [2], [3]
D1092		Moxifloxacin	C21H24FN3O4	152946	Major		Inter Info	[1], [2], [3]
D1102		Nalidixic acid	C12H12N2O3	4421	Major		Inter Info	[1], [2], [3]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Major		Inter Info	[1], [2], [3]
D0712		Gatifloxacin	C19H22FN3O4	5379	Major		Inter Info	[31], [32], [1]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Major		Inter Info	[1], [2], [3]
D0919		Levofloxacin	C18H20FN3O4	149096	Major		Inter Info	[1], [2], [3]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Major		Inter Info	[1], [2], [3]
D1155		Norfloxacin	C16H18FN3O3	4539	Major		Inter Info	[1], [2], [3]
D1165		Ofloxacin	C18H20FN3O4	4583	Major		Inter Info	[1], [2], [3]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Major		Inter Info	[1], [2], [3]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Major		Inter Info	[1], [2], [3]
D0012		Acetazolamide	C4H6N4O3S2	1986	Moderate		Inter Info	[33], [34], [35]
D0080		Amprenavir	C25H35N3O6S	65016	Moderate		Inter Info	[33], [34], [35]
D0114		Asparaginase Escherichia coli	NA	NA	Moderate		Inter Info	[33], [34], [35]
D0158		Bendroflumethiazide	C15H14F3N3O4S2	2315	Moderate		Inter Info	[33], [34], [35]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[33], [34], [35]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[33], [34], [35]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[33], [34], [35]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[33], [34], [35]
D0370		Clozapine	C18H19ClN4	135398737	Moderate		Inter Info	[33], [34], [35]
D0387		Conjugated estrogens	C18H21NaO5S	45357473	Moderate		Inter Info	[33], [34], [35]
D0388		Conjugated estrogens (topical)	C18H21NaO5S	45357473	Moderate		Inter Info	[33], [34], [35]
D0487		Diethylstilbestrol	C18H20O2	448537	Moderate		Inter Info	[33], [34], [35]
D0581		Epinephrine	C9H13NO3	5816	Moderate		Inter Info	[33], [34], [35]
D0606		Estradiol	C18H24O2	5757	Moderate		Inter Info	[33], [34], [35]
D0607		Estradiol (topical)	C18H24O2	5757	Moderate		Inter Info	[33], [34], [35]
D0609		Estrone	C18H22O2	5870	Moderate		Inter Info	[33], [34], [35]
D0626		Etonogestrel	C22H28O2	6917715	Moderate		Inter Info	[33], [34], [35]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[33], [34], [35]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[33], [34], [35]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[33], [34], [35]
D0737		Goserelin	C59H84N18O14	5311128	Moderate		Inter Info	[33], [34], [35]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[33], [34], [35]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[33], [34], [35]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[33], [34], [35]
D0799		Indinavir	C36H47N5O4	5362440	Moderate		Inter Info	[33], [34], [35]
D0908		Leuprolide	C59H84N16O12	657181	Moderate		Inter Info	[33], [34], [35]
D0922		Levonorgestrel	C21H28O2	13109	Moderate		Inter Info	[33], [34], [35]
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[33], [34], [35]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[33], [34], [35]
D0990		Medroxyprogesterone acetate	C24H34O4	6279	Moderate		Inter Info	[33], [34], [35]
D0993		Megestrol acetate	C24H32O4	11683	Moderate		Inter Info	[33], [34], [35]
D1013		Metaraminol	C9H13NO2	5906	Moderate		Inter Info	[33], [34], [35]
D1018		Methazolamide	C5H8N4O3S2	4100	Moderate		Inter Info	[33], [34], [35]
D1027		Methoxamine	C11H17NO3	6082	Moderate		Inter Info	[33], [34], [35]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[33], [34], [35]
D1119		Nelfinavir	C32H45N3O4S	64143	Moderate		Inter Info	[33], [34], [35]
D1129		Niacin	C6H5NO2	938	Moderate		Inter Info	[33], [34], [35]
D1153		Norepinephrine	C8H11NO3	439260	Moderate		Inter Info	[33], [34], [35]
D1154		Norethisterone	C20H26O2	6230	Moderate		Inter Info	[33], [34], [35]
D1163		Octreotide	C49H66N10O10S2	448601	Moderate		Inter Info	[166], [167], [168]
D1166		Olanzapine	C17H20N4S	135398745	Moderate		Inter Info	[33], [34], [35]
D1185		Orciprenaline	C11H17NO3	4086	Moderate		Inter Info	[33], [34], [35]
D1234		Pegaspargase	C14H19NO	436058	Moderate		Inter Info	[33], [34], [35]
D1246		Pentamidine	C19H24N4O2	4735	Moderate		Inter Info	[172], [173], [174]
D1276		Phenylephrine	C9H13NO2	6041	Moderate		Inter Info	[33], [34], [35]
D1281		Phenylpropanolamine	C9H13NO	26934	Moderate		Inter Info	[33], [34], [35]
D1283		Phenytoin	C15H12N2O2	1775	Moderate		Inter Info	[176], [177], [178]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[33], [34], [35]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[33], [34], [35]
D1348		Progesterone	C21H30O2	5994	Moderate		Inter Info	[33], [34], [35]
D1349		Progesterone (topical)	C21H30O2	5994	Moderate		Inter Info	[33], [34], [35]
D1351		Promazine	C17H20N2S	4926	Moderate		Inter Info	[33], [34], [35]
D1355		Propiomazine	C20H24N2OS	4940	Moderate		Inter Info	[33], [34], [35]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[33], [34], [35]
D1415		Ritonavir	C37H48N6O5S2	392622	Moderate		Inter Info	[33], [34], [35]
D1494		Somatotropin	NA	NA	Moderate		Inter Info	[33], [34], [35]
D1572		Thiethylperazine	C22H29N3S2	5440	Moderate		Inter Info	[33], [34], [35]
D1574		Thioridazine	C21H26N2S2	5452	Moderate		Inter Info	[33], [34], [35]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[33], [34], [35]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[33], [34], [35]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[33], [34], [35]
D0113		Asparaginase Erwinia chrysanthemi	NA	NA	Moderate		Inter Info	[33], [34], [35]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[33], [34], [35]
D0199		Brentuximab vedotin	NA	NA	Moderate		Inter Info	[33], [34], [35]
D0202		Brexpiprazole	C25H27N3O2S	11978813	Moderate		Inter Info	[33], [34], [35]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[33], [34], [35]
D0232		Calaspargase pegol	NA	NA	Moderate		Inter Info	[33], [34], [35]
D0262		Cariprazine	C21H32Cl2N4O	11154555	Moderate		Inter Info	[33], [34], [35]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[33], [34], [35]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[33], [34], [35]
D0389		Copanlisib	C23H28N8O4	135565596	Moderate		Inter Info	[33], [34], [35]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[33], [34], [35]
D0416		Danazol	C22H27NO2	28417	Moderate		Inter Info	[33], [34], [35]
D0426		Darunavir	C27H37N3O7S	213039	Moderate		Inter Info	[33], [34], [35]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[33], [34], [35]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[33], [34], [35]
D0474		Diazoxide	C8H7ClN2O2S	3019	Moderate		Inter Info	[33], [34], [35]
D0479		Diclofenamide	C6H6Cl2N2O4S2	3038	Moderate		Inter Info	[33], [34], [35]
D0484		Dienestrol (topical)	C18H18O2	667476	Moderate		Inter Info	[33], [34], [35]
D0510		Dobutamine	C18H23NO3	36811	Moderate		Inter Info	[33], [34], [35]
D0517		Dopamine	C8H11NO2	681	Moderate		Inter Info	[33], [34], [35]
D0536		Drospirenone	C24H30O3	68873	Moderate		Inter Info	[33], [34], [35]
D0571		Enfortumab vedotin	NA	NA	Moderate		Inter Info	[33], [34], [35]
D0579		Ephedrine	C10H15NO	9294	Moderate		Inter Info	[33], [34], [35]
D0605		Esterified estrogens	NA	NA	Moderate		Inter Info	[33], [34], [35]
D0608		Estramustine	C23H31Cl2NO3	259331	Moderate		Inter Info	[33], [34], [35]
D0610		Estrone sulfate	C18H22O5S	3001028	Moderate		Inter Info	[33], [34], [35]
D0611		Estrone sulfate (topical)	C18H22O5S	3001028	Moderate		Inter Info	[33], [34], [35]
D0613		Etacrynic acid	C13H12Cl2O4	3278	Moderate		Inter Info	[33], [34], [35]
D0619		Ethinylestradiol	C20H24O2	5991	Moderate		Inter Info	[33], [34], [35]
D0629		Everolimus	C53H83NO14	6442177	Moderate		Inter Info	[33], [34], [35]
D0692		Fosamprenavir	C25H36N3O9PS	131536	Moderate		Inter Info	[33], [34], [35]
D0697		Fosphenytoin	C16H15N2O6P	56339	Moderate		Inter Info	[176], [177], [178]
D0758		Histrelin	C66H86N18O12	25077993	Moderate		Inter Info	[33], [34], [35]
D0771		Hydrochlorothiazide	C7H8ClN3O4S2	3639	Moderate		Inter Info	[33], [34], [35]
D0791		Iloperidone	C24H27FN2O4	71360	Moderate		Inter Info	[33], [34], [35]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[33], [34], [35]
D0859		Isoprenaline	C11H17NO3	3779	Moderate		Inter Info	[33], [34], [35]
D0891		Lanreotide	C54H69N11O10S2	71349	Moderate		Inter Info	[166], [167], [168]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Moderate		Inter Info	[33], [34], [35]
D0959		Lumateperone	C24H28FN3O	21302490	Moderate		Inter Info	[33], [34], [35]
D0961		Lurasidone	C28H36N4O2S	213046	Moderate		Inter Info	[33], [34], [35]
D1002		Mephentermine	C11H17N	3677	Moderate		Inter Info	[33], [34], [35]
D1010		Mesoridazine	C21H26N2OS2	4078	Moderate		Inter Info	[33], [34], [35]
D1019		Methdilazine	C18H20N2S	14677	Moderate		Inter Info	[33], [34], [35]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[33], [34], [35]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[33], [34], [35]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[33], [34], [35]
D1132		Nicotinamide	C6H6N2O	936	Moderate		Inter Info	[33], [34], [35]
D1157		Norgestrel	C21H28O2	13109	Moderate		Inter Info	[33], [34], [35]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Moderate		Inter Info	[33], [34], [35]
D1215		Paliperidone	C23H27FN4O3	115237	Moderate		Inter Info	[33], [34], [35]
D1230		Pasireotide	C58H66N10O9	9941444	Moderate		Inter Info	[166], [167], [168]
D1257		Perphenazine	C21H26ClN3OS	4748	Moderate		Inter Info	[33], [34], [35]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[33], [34], [35]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[33], [34], [35]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[33], [34], [35]
D1363		Pseudoephedrine	C10H15NO	7028	Moderate		Inter Info	[33], [34], [35]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[33], [34], [35]
D1370		Quinestrol	C25H32O2	9046	Moderate		Inter Info	[33], [34], [35]
D1414		Ritodrine	C17H21NO3	33572	Moderate		Inter Info	[33], [34], [35]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[33], [34], [35]
D1444		Saquinavir	C38H50N6O5	441243	Moderate		Inter Info	[33], [34], [35]
D1476		Sirolimus	C51H79NO13	5284616	Moderate		Inter Info	[33], [34], [35]
D1493		Somapacitan	C54H95N13O20S2	129894493	Moderate		Inter Info	[33], [34], [35]
D1495		Somatrem	C43H72N14O14	5487805	Moderate		Inter Info	[33], [34], [35]
D1531		Tagraxofusp	NA	NA	Moderate		Inter Info	[33], [34], [35]
D1549		Temsirolimus	C56H87NO16	6918289	Moderate		Inter Info	[33], [34], [35]
D1900		Teprotumumab	NA	NA	Moderate		Inter Info	[33], [34], [35]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[33], [34], [35]
D1902		Tesamorelin	C221H366N72O67S	16137828	Moderate		Inter Info	[33], [34], [35]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[33], [34], [35]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[33], [34], [35]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Moderate		Inter Info	[33], [34], [35]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[33], [34], [35]
D1651		Triptorelin	C64H82N18O13	25074470	Moderate		Inter Info	[33], [34], [35]
D1707		Vorinostat	C14H20N2O3	5311	Moderate		Inter Info	[33], [34], [35]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[33], [34], [35]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[33], [34], [35]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[33], [34], [35]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[33], [34], [35]
D1638		Triflupromazine	C18H19F3N2S	5568	Moderate		Inter Info	[33], [34], [35]
D1726		Ziprasidone	C21H21ClN4OS	60854	Moderate		Inter Info	[33], [34], [35]
D1762		Clobetasol (topical)	C22H28ClFO4	5311051	Minor		Inter Info	[257], [258], [259]
D1770		Desonide (topical)	C24H32O6	5311066	Minor		Inter Info	[257], [258], [259]
D0455		Dexamethasone (ophthalmic)	C22H29FO5	5743	Minor		Inter Info	[133], [169], [170]
D1772		Dexamethasone (topical)	C22H29FO5	5743	Minor		Inter Info	[257], [258], [259]
D1786		Fluocinonide (topical)	C26H32F2O7	9642	Minor		Inter Info	[257], [258], [259]
D1788		Flurandrenolide (topical)	C24H33FO6	15209	Minor		Inter Info	[257], [258], [259]
D0685		Fluticasone (topical)	C22H27F3O4S	5311101	Minor		Inter Info	[257], [258], [259]
D1804		Halcinonide (topical)	C24H32ClFO5	443943	Minor		Inter Info	[257], [258], [259]
D1844		Methylprednisolone (topical)	C22H30O5	6741	Minor		Inter Info	[257], [258], [259]
D1869		Prednicarbate (topical)	C27H36O8	6714002	Minor		Inter Info	[257], [258], [259]
	Antagonize the effect of antihypertensive agents					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1888		Sermorelin	C149H246N44O42S	16132413	Moderate		Inter Info	[33], [34], [35]
D1908		Thyrotropin alfa	C16H22N6O4	32281	Moderate		Inter Info	[33], [34], [35]
D1735		Alclometasone (topical)	C22H29ClO5	5311000	Minor		Inter Info	[257], [258], [259]
D1737		Amcinonide	C28H35FO7	443958	Minor		Inter Info	[257], [258], [259]
D1748		Betamethasone (topical)	C22H29FO5	9782	Minor		Inter Info	[257], [258], [259]
D1763		Clocortolone (topical)	C22H28ClFO4	5311052	Minor		Inter Info	[257], [258], [259]
D1771		Desoximetasone (topical)	C22H29FO4	5311067	Minor		Inter Info	[257], [258], [259]
D1773		Diflorasone (topical)	C22H28F2O5	71415	Minor		Inter Info	[257], [258], [259]
D1813		Hydrocortisone (topical)	C21H30O5	5754	Minor		Inter Info	[257], [258], [259]
D1911		Triamcinolone (topical)	C21H27FO6	31307	Minor		Inter Info	[257], [258], [259]
D1916		Ulobetasol (topical)	C22H27ClF2O4	5311167	Minor		Inter Info	[257], [258], [259]

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