Details of Drug

Details of Drug

 Drug General Information (ID: D1218)
  Drug Name
Pancrelipase
  Drug Type Protein/peptide
  Drug Synonymous
Endothal-disodium; 13114-29-9; Sodium Demethylcantharidate; 129-67-9; Aguathol; Disodium endothall; Sodium 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate; disodium;7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate; Sodium 3-carboxy-7-oxabicyclo[2.2.1]heptane-2-carboxylate; Pancrelipase; Disodium endothal; 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, disodium salt; Sodium norcantharidin; ENDOTHALL-SODIUM; Sodium-Demethylcantharidate; 53608-75-6; SCHEMBL1006891; DTXSID1041899; CHEBI:81916; FT-0775390; C18724; Q27155657
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  Therapeutic Class Digestive Enzymes
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C8H8Na2O5
  InChI InChI=1S/C8H10O5.2Na/c9-7(10)5-3-1-2-4(13-3)6(5)8(11)12;;/h3-6H,1-2H2,(H,9,10)(H,11,12);;/q;2*+1/p-2
  InChIKey XRHVZWWRFMCBAZ-UHFFFAOYSA-L
  Canonical SMILES C1CC2C(C(C1O2)C(=O)[O-])C(=O)[O-].[Na+].[Na+]
  External Link
Pubchem ID 8519

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
AM007  Pharmacodynamic antagonistic effects
BM003  Complex formation
BM005  Altered gastric pH
BM009  Altered absorption (Unspecific)
BM084  Antagonize the effect of alpha-glucosidase inhibitors
  Relation Graph
 Full list of drugs interacting with Pancrelipase
      Affected gastrointestinal absorption
   Complex formation Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1369
 
Quinapril
 
C25H30N2O5
 
54892 
Moderate    Inter Info   
[4], [5]
   Altered gastric pH Drug Num:  5
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0049
 
Aluminum hydroxide
 
AlH3O3
 
10176082 
Moderate    Inter Info   
[3], [4], [5]
D0236
 
Calcium carbonate
 
CCaO3
 
10112 
Moderate    Inter Info   
[3], [4], [5]
D0967
 
Magaldrate
 
AlHMgO5S+2
 
3086011 
Moderate    Inter Info   
[3], [4], [5]
D0973
 
Magnesium hydroxide
 
H2MgO2
 
14791 
Moderate    Inter Info   
[3], [4], [5]
D1480
 
Sodium bicarbonate
 
CHNaO3
 
516892 
Moderate    Inter Info   
[3], [4], [5]
   Altered absorption (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0732
 
Glycerol phenylbutyrate
 
C33H38O6
 
10482134 
Moderate    Inter Info   
[4], [6]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of alpha-glucosidase inhibitors Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0009
 
Acarbose
 
C25H43NO18
 
41774 
Moderate    Inter Info   
[1], [2]
D1064
 
Miglitol
 
C8H17NO5
 
441314 
Moderate    Inter Info   
[1], [2]
References
1 Product Information. Glyset (miglitol). Bayer, West Haven, CT.
2 Product Information. Precose (acarbose). Bayer, West Haven, CT.
3 Cerner Multum, Inc. "Australian Product Information.".
4 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
5 Multum Information Services, Inc. Expert Review Panel.
6 Product Information. Ravicti (glycerol phenylbutyrate). Hyperion Therapeutics Inc, South San Francisco, CA.