Details of Drug

Drug General Information (ID: D0084)
Drug Name	Anagrelide
Drug Type	Small molecule
Drug Synonymous	Anagrelida; Anagrelidum; BL 416201; Agrylin (TN); Anagrelida [INN-Spanish]; Anagrelide [BAN:INN]; Anagrelide [INN:BAN]; Anagrelidum [INN-Latin]; Xagrid (TN); Anagrelide (INN/BAN); 6,7-Dichlor-1,5-dihydroimidazo(2,1-b)chinazolin-2(3H)-on; 6,7-Dichloro-1,5-dihydroimidazo(2,1-b)quinazolin-2(3H)-one; 6,7-dichloro-1,5-dihydroimidazo[2,1-]quinazolin-2(3H)-one; 6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one Click to Show/Hide
Disease Class	3B63: Thrombocytosis
Therapeutic Class	Antithrombotic Agents
Structure
Structure	3D Structure		2D Structure
Formula	C10H7Cl2N3O
InChI	1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16)
InChIKey	OTBXOEAOVRKTNQ-UHFFFAOYSA-N
Canonical SMILES	C1C2=C(C=CC(=C2Cl)Cl)N=C3N1CC(=O)N3
External Link
	Pubchem ID	135409400
	CAS Number	68475-42-3
	CHEBI ID	142290
	TTD ID	D0D1HW

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM004 Affected intra/extra-hepatic metabolism AM006 Pharmacodynamic additive effects BM017 CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM042 Additive hypotensive effects BM050 Increased risk of bleeding BM076 Increased risk of prolong QT interval BM081 Increased risk of ventricular arrhythmias
Relation Graph

Full list of drugs interacting with Anagrelide
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 46
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1596		Tizanidine	C9H8ClN5S	5487	Major		Inter Info	[183], [184], [185], [186], [187], [188], [189], [190]
D0002		Abametapir (topical)	C12H12N2	15664	Moderate		Inter Info	[201]
D0011		Acetaminophen	C8H9NO2	1983	Moderate		Inter Info	[2], [3], [4]
D0028		Albendazole	C12H15N3O2S	2082	Moderate		Inter Info	[2], [3], [4]
D0043		Alosetron	C17H18N4O	2099	Moderate		Inter Info	[202]
D0045		Alprazolam	C17H13ClN4	2118	Moderate		Inter Info	[2], [3], [4]
D0133		Axitinib	C22H18N4OS	6450551	Moderate		Inter Info	[2], [3], [4]
D0157		Bendamustine	C16H21Cl2N3O2	65628	Moderate		Inter Info	[212]
D0251		Capmatinib	C23H17FN6O	25145656	Moderate		Inter Info	[4]
D0267		Carvedilol	C24H26N2O4	2585	Moderate		Inter Info	[2], [3], [4]
D0317		Chlordiazepoxide	C16H14ClN3O	2712	Moderate		Inter Info	[2], [3], [4]
D0337		Cimetidine	C10H16N6S	2756	Moderate		Inter Info	[4]
D0545		Echinacea	NA	NA	Moderate		Inter Info	[4]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[4]
D0724		Givosiran	C78H139N11O30	119058042	Moderate		Inter Info	[4]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[4]
D0916		Levobupivacaine	C18H28N2O	92253	Moderate		Inter Info	[3], [264]
D0927		Lidocaine	C14H22N2O	3676	Moderate		Inter Info	[2], [3], [4]
D0994		Melatonin	C13H16N2O2	896	Moderate		Inter Info	[2], [3], [4]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[4]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[2], [3], [4]
D1160		Obeticholic acid	C26H44O4	447715	Moderate		Inter Info	[4]
D1166		Olanzapine	C17H20N4S	135398745	Moderate		Inter Info	[269], [270], [271], [272], [3], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283], [284], [285]
D1299		Pirfenidone	C12H11NO	40632	Moderate		Inter Info	[3], [292]
D1357		Propranolol	C16H21NO2	4946	Moderate		Inter Info	[2], [3], [4]
D1378		Ramelteon	C16H21NO2	208902	Moderate		Inter Info	[303]
D1385		Rasagiline	C12H13N	3052776	Moderate		Inter Info	[2], [3], [4]
D1405		Riluzole	C8H5F3N2OS	5070	Moderate		Inter Info	[2], [3], [4]
D1421		Rofecoxib	C17H14O4S	5090	Moderate		Inter Info	[4]
D1422		Roflumilast	C17H14Cl2F2N2O3	449193	Moderate		Inter Info	[3], [304], [305]
D1427		Ropinirole	C16H24N2O	5095	Moderate		Inter Info	[306], [307]
D1428		Ropivacaine	C17H26N2O	175805	Moderate		Inter Info	[2], [3], [4]
D1505		Stiripentol	C14H18O3	5311454	Moderate		Inter Info	[3], [140], [308]
D1525		Tacrine	C13H14N2	1935	Moderate		Inter Info	[2], [3], [4]
D1536		Tasimelteon	C15H19NO2	10220503	Moderate		Inter Info	[309]
D1570		Theophylline	C7H8N4O2	2153	Moderate		Inter Info	[2], [3], [4]
D1571		Thiabendazole	C10H7N3S	5430	Moderate		Inter Info	[4]
D1690		Verapamil	C27H38N2O4	2520	Moderate		Inter Info	[4]
D1721		Zileuton	C11H12N2O2S	60490	Moderate		Inter Info	[4]
D1729		Zolpidem	C19H21N3O	5732	Moderate		Inter Info	[2], [3], [4]
D0193		Bortezomib	C19H25BN4O4	387447	Moderate		Inter Info	[2], [3], [4]
D0231		Caffeine	C8H10N4O2	2519	Moderate		Inter Info	[2], [3], [4]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[4]
D0821		Interferon alfa-2a, Recombinant	NA	NA	Moderate		Inter Info	[4]
D1237		Peginterferon alfa-2a	NA	NA	Moderate		Inter Info	[4]
D1581		Ticlopidine	C14H14ClNS	5472	Moderate		Inter Info	[4]
	CYP450 enzyme induction					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0255		Carbamazepine	C15H12N2O	2554	Moderate		Inter Info	[2], [3], [4]
D1167		Olaparib	C24H23FN4O3	23725625	Moderate		Inter Info	[2], [3], [24]
D1179		Omeprazole	C17H19N3O3S	4594	Moderate		Inter Info	[2], [3], [4]
D1265		Phenobarbital	C12H12N2O3	4763	Moderate		Inter Info	[2], [3], [4]
D1400		Rifampicin	C43H58N4O12	135398735	Moderate		Inter Info	[2], [3], [4]
Pharmacodynamic additive effects
	Additive hypotensive effects					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0082		Amrinone	C10H9N3O	3698	Moderate		Inter Info	[4]
D0336		Cilostazol	C20H27N5O2	2754	Moderate		Inter Info	[4]
D1067		Milrinone	C12H9N3O	4197	Moderate		Inter Info	[4]
	Increased risk of bleeding					Drug Num: 89
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0005		Abciximab	NA	NA	Major		Inter Info	[5], [6]
D0008		Acalabrutinib	C26H23N7O2	71226662	Major		Inter Info	[7]
D0096		Apixaban	C25H25N5O4	10182969	Major		Inter Info	[3], [25]
D0102		Ardeparin	C26H42N2O37S5	772	Major		Inter Info	[26], [27], [28], [29], [30], [31], [32]
D0104		Argatroban	C23H36N6O5S	92722	Major		Inter Info	[33], [34], [35]
D0129		Avapritinib	C26H27FN10	118023034	Major		Inter Info	[3], [38]
D0176		Betrixaban	C23H22ClN5O3	10275777	Major		Inter Info	[39]
D0250		Caplacizumab	NA	NA	Major		Inter Info	[2], [3], [40]
D0414		Dalteparin	C26H42N2O37S5	772	Major		Inter Info	[26], [27], [28], [29], [30], [31], [32]
D0415		Danaparoid	NA	NA	Major		Inter Info	[26], [27], [28], [29], [30], [31], [32]
D0432		Deferasirox	C21H15N3O4	214348	Major		Inter Info	[62], [63]
D0435		Defibrotide	C20H21N4O6P	135565962	Major		Inter Info	[3], [64]
D0447		Desirudin	C287H440N80O110S6	16129703	Major		Inter Info	[33], [34], [35]
D0551		Edoxaban	C24H30ClN7O4S	10280735	Major		Inter Info	[66]
D0574		Enoxaparin	C26H42N2O37S5	772	Major		Inter Info	[26], [27], [28], [29], [30], [31], [32]
D0690		Fondaparinux	C31H53N3O49S8	5282448	Major		Inter Info	[26], [27], [28], [29], [30], [31], [32]
D0785		Ibrutinib	C25H24N6O2	24821094	Major		Inter Info	[105], [106], [3], [107]
D0805		Inotersen	C230H318N69O121P19S19	121492004	Major		Inter Info	[3], [62], [109]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Major		Inter Info	[62], [122]
D1313		Ponatinib	C29H27F3N6O	24826799	Major		Inter Info	[137]
D1328		Prasugrel	C20H20FNO3S	6918456	Major		Inter Info	[3], [138]
D1380		Ramucirumab	NA	NA	Major		Inter Info	[139]
D1387		Regorafenib	C21H15ClF4N4O3	11167602	Major		Inter Info	[3], [140], [141]
D1417		Rivaroxaban	C19H18ClN3O5S	9875401	Major		Inter Info	[166]
D1588		Tinzaparin	C26H42N2O37S5	772	Major		Inter Info	[26], [27], [28], [29], [30], [31], [32]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Major		Inter Info	[182]
D1593		Tirofiban	C22H36N2O5S	60947	Major		Inter Info	[5], [6]
D1705		Vorapaxar	C29H33FN2O4	10077130	Major		Inter Info	[192]
D1718		Zanubrutinib	C27H29N5O3	135565884	Major		Inter Info	[62]
D0189		Bivalirudin	C98H138N24O33	16129704	Major		Inter Info	[33], [34], [35]
D0537		Drotrecogin alfa	NA	NA	Major		Inter Info	[196]
D0588		Eptifibatide	C35H49N11O9S2	448812	Major		Inter Info	[5], [6]
D0784		Ibritumomab tiuxetan	NA	NA	Major		Inter Info	[197]
D0904		Lepirudin	C287H440N80O111S6	118856773	Major		Inter Info	[33], [34], [35]
D1613		Tositumomab	NA	NA	Major		Inter Info	[198], [199]
D1614		Tositumomab (I-131)	NA	NA	Major		Inter Info	[198], [199]
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[2], [3], [4]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[213], [214], [215]
D0211		Bromfenac (ophthalmic)	C15H12BrNO3	60726	Moderate		Inter Info	[213], [214], [215]
D1769		Deoxycholic acid	C24H40O4	222528	Moderate		Inter Info	[62], [219]
D0451		Desvenlafaxine	C16H25NO2	125017	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D0457		Dexfenfluramine	C12H16F3N	66265	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[213], [214], [215]
D0477		Diclofenac (ophthalmic)	C14H11Cl2NO2	3033	Moderate		Inter Info	[213], [214], [215]
D0478		Diclofenac (topical)	C14H11Cl2NO2	3033	Moderate		Inter Info	[213], [214], [215]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[213], [214], [215]
D0539		Duloxetine	C18H19NOS	60835	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D0586		Epoprostenol	C20H32O5	5282411	Moderate		Inter Info	[259], [260], [261]
D0624		Etodolac	C17H21NO3	3308	Moderate		Inter Info	[213], [214], [215]
D0641		Fenfluramine	C12H16F3N	3337	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[213], [214], [215]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[213], [214], [215]
D0681		Flurbiprofen (ophthalmic)	C15H13FO2	3394	Moderate		Inter Info	[213], [214], [215]
D0752		Hemin	C34H32FeN4O4	26945	Moderate		Inter Info	[263]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[213], [214], [215]
D0792		Iloprost	C22H32O4	5311181	Moderate		Inter Info	[259], [260], [261]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[213], [214], [215]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[213], [214], [215]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[213], [214], [215]
D0883		Ketorolac (ophthalmic)	C15H13NO3	3826	Moderate		Inter Info	[213], [214], [215]
D0920		Levomilnacipran	C15H22N2O	6917779	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[213], [214], [215]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[213], [214], [215]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[213], [214], [215]
D1066		Milnacipran	C15H22N2O	65833	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[213], [214], [215]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[213], [214], [215]
D1123		Nepafenac (ophthalmic)	C15H14N2O2	151075	Moderate		Inter Info	[213], [214], [215]
D1139		Nintedanib	C31H33N5O4	135423438	Moderate		Inter Info	[267]
D1140		Niraparib	C19H20N4O	24958200	Moderate		Inter Info	[3], [268]
D1178		Omega-3 fatty acids	C60H92O6	56842239	Moderate		Inter Info	[3], [286], [287]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[213], [214], [215]
D1229		Paroxetine	C19H20FNO3	43815	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D1249		Pentosan polysulfate	C10H18O21S4	37720	Moderate		Inter Info	[62], [288]
D1251		Pentoxifylline	C13H18N4O3	4740	Moderate		Inter Info	[1], [289]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[213], [214], [215]
D1300		Piroxicam	C15H13N3O4S	54676228	Moderate		Inter Info	[213], [214], [215]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[213], [214], [215]
D1523		Suprofen (ophthalmic)	C14H12O3S	5359	Moderate		Inter Info	[213], [214], [215]
D1579		Ticagrelor	C23H28F2N6O4S	9871419	Moderate		Inter Info	[3], [311]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[213], [214], [215]
D1625		Treprostinil	C23H34O5	6918140	Moderate		Inter Info	[259], [260], [261]
D1696		Vilazodone	C26H27N5O2	6918314	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D1708		Vortioxetine	C18H22N2S	9966051	Moderate		Inter Info	[220], [221], [222], [223], [2], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [194], [240], [241], [242], [70], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254], [255]
D1815		Icosapent	C20H30O2	446284	Moderate		Inter Info	[3], [286], [287]
D0253		Capsicum	NA	NA	Minor		Inter Info	[312]
D0309		Chamomile	C15H10O5	5280443	Minor		Inter Info	[312], [313], [314]
D0368		Clove	NA	NA	Minor		Inter Info	[312], [315], [316], [317]
	Increased risk of prolong QT interval					Drug Num: 181
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0003		Abarelix	C72H95ClN14O14	16131215	Major		Inter Info	[1], [2], [3], [4]
D0007		Abiraterone	C24H31NO	132971	Major		Inter Info	[1], [2], [3], [4]
D0036		Alfuzosin	C19H27N5O4	2092	Major		Inter Info	[1], [2], [3], [4]
D0037		Alimemazine	C18H22N2S	5574	Major		Inter Info	[2], [3], [4]
D0066		Amiodarone	C25H29I2NO3	2157	Major		Inter Info	[1], [2], [3], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0067		Amisulpride	C17H27N3O4S	2159	Major		Inter Info	[1], [2], [3], [4]
D0068		Amitriptyline	C20H23N	2160	Major		Inter Info	[1], [2], [3], [4]
D0095		Apalutamide	C21H15F4N5O2S	24872560	Major		Inter Info	[1], [2], [3], [4]
D0097		Apomorphine	C17H17NO2	6005	Major		Inter Info	[1], [2], [3], [4]
D0112		Asenapine	C17H16ClNO	3036780	Major		Inter Info	[1], [2], [3], [4]
D0115		Astemizole	C28H31FN4O	2247	Major		Inter Info	[1], [2], [3], [4]
D0119		Atomoxetine	C17H21NO	54841	Major		Inter Info	[1], [2], [3], [4]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Major		Inter Info	[1], [2], [3], [4]
D0170		Bepridil	C24H34N2O	2351	Major		Inter Info	[1], [2], [3], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0180		Bicalutamide	C18H14F4N2O4S	2375	Major		Inter Info	[1], [2], [3], [4]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Major		Inter Info	[1], [2], [3], [4]
D0219		Buprenorphine	C29H41NO4	644073	Major		Inter Info	[1], [2], [3], [4]
D0230		Cabozantinib	C28H24FN3O5	25102847	Major		Inter Info	[1], [2], [3], [4]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Major		Inter Info	[1], [2], [3], [4]
D0320		Chloroquine	C18H26ClN3	2719	Major		Inter Info	[41], [3], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59]
D0324		Chlorpromazine	C17H19ClN2S	2726	Major		Inter Info	[1], [2], [3], [4]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Major		Inter Info	[1], [2], [3], [4]
D0342		Cisapride	C23H29ClFN3O4	6917698	Major		Inter Info	[1], [2], [3], [12], [60], [61]
D0349		Clarithromycin	C38H69NO13	84029	Major		Inter Info	[1], [2], [3], [4]
D0358		Clofazimine	C27H22Cl2N4	2794	Major		Inter Info	[1], [2], [3], [4]
D0361		Clomipramine	C19H23ClN2	2801	Major		Inter Info	[1], [2], [3], [4]
D0370		Clozapine	C18H19ClN4	135398737	Major		Inter Info	[1], [2], [3], [4]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Major		Inter Info	[1], [2], [3], [4]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Major		Inter Info	[1], [2], [3], [4]
D0429		Daunorubicin	C27H29NO10	30323	Major		Inter Info	[1], [2], [3], [4]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Major		Inter Info	[2], [3], [4]
D0437		Degarelix	C82H103ClN18O16	16136245	Major		Inter Info	[1], [2], [3], [4]
D0446		Desipramine	C18H22N2	2995	Major		Inter Info	[1], [2], [3], [4]
D0452		Deutetrabenazine	C19H27NO3	73437646	Major		Inter Info	[1], [2], [3], [4]
D0467		Dextropropoxyphene	C22H29NO2	10100	Major		Inter Info	[2], [3], [4]
D0508		Disopyramide	C21H29N3O	3114	Major		Inter Info	[1], [2], [3], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0514		Dolasetron	C19H20N2O3	3033818	Major		Inter Info	[1], [2], [3], [4]
D0525		Doxepin	C19H21NO	667477	Major		Inter Info	[1], [2], [3], [4]
D0526		Doxepin (topical)	C19H21NO	667477	Major		Inter Info	[2], [3], [4]
D0528		Doxorubicin	C27H29NO11	31703	Major		Inter Info	[1], [2], [3], [4]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Major		Inter Info	[2], [3], [4]
D0534		Dronedarone	C31H44N2O5S	208898	Major		Inter Info	[1], [2], [3], [65]
D0535		Droperidol	C22H22FN3O2	3168	Major		Inter Info	[1], [2], [3], [4]
D0554		Efavirenz	C14H9ClF3NO2	64139	Major		Inter Info	[67]
D0569		Encorafenib	C22H27ClFN7O4S	50922675	Major		Inter Info	[1], [2], [3], [4]
D0577		Entrectinib	C31H34F2N6O2	25141092	Major		Inter Info	[1], [2], [3], [4]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Major		Inter Info	[1], [2], [3], [4]
D0584		Epirubicin	C27H29NO11	41867	Major		Inter Info	[1], [2], [3], [4]
D0594		Eribulin	C40H59NO11	11354606	Major		Inter Info	[1], [2], [3], [4]
D0599		Escitalopram	C20H21FN2O	146570	Major		Inter Info	[1], [68], [2], [3], [69], [70], [24]
D0632		Ezogabine	C16H18FN3O2	121892	Major		Inter Info	[1], [2], [3], [4]
D0664		Flecainide	C17H20F6N2O3	3356	Major		Inter Info	[1], [2], [3], [4]
D0676		Fluoxetine	C17H18F3NO	3386	Major		Inter Info	[1], [2], [3], [4]
D0678		Fluphenazine	C22H26F3N3OS	3372	Major		Inter Info	[1], [2], [3], [4]
D0682		Flutamide	C11H11F3N2O3	3397	Major		Inter Info	[1], [2], [3], [4]
D0694		Foscarnet	CH3O5P	3415	Major		Inter Info	[1], [2], [3], [4]
D0700		Fostemsavir	C25H26N7O8P	11319217	Major		Inter Info	[1], [2], [3], [4]
D0712		Gatifloxacin	C19H22FN3O4	5379	Major		Inter Info	[73], [74], [75], [1], [2], [3], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Major		Inter Info	[1], [2], [3], [4]
D0720		Gilteritinib	C29H44N8O3	49803313	Major		Inter Info	[1], [2], [3], [4]
D0725		Glasdegib	C21H22N6O	25166913	Major		Inter Info	[1], [2], [3], [4]
D0738		Granisetron	C18H24N4O	5284566	Major		Inter Info	[1], [2], [3], [4]
D0740		Grepafloxacin	C19H22FN3O3	72474	Major		Inter Info	[74], [1], [2], [3], [96], [97], [98]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Major		Inter Info	[99], [1], [2], [3], [100], [101], [102], [103], [104]
D0750		Haloperidol	C21H23ClFNO2	3559	Major		Inter Info	[1], [2], [3], [4]
D0751		Halothane	C2HBrClF3	3562	Major		Inter Info	[1], [2], [3], [4]
D0758		Histrelin	C66H86N18O12	25077993	Major		Inter Info	[1], [2], [3], [4]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Major		Inter Info	[41], [3], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59]
D0781		Hydroxyzine	C21H27ClN2O2	3658	Major		Inter Info	[1], [2], [3], [4]
D0787		Ibutilide	C20H36N2O3S	60753	Major		Inter Info	[1], [2], [3], [4]
D0788		Idarubicin	C26H27NO9	42890	Major		Inter Info	[1], [2], [3], [4]
D0791		Iloperidone	C24H27FN2O4	71360	Major		Inter Info	[1], [2], [3], [108], [24]
D0806		Inotuzumab ozogamicin	NA	NA	Major		Inter Info	[1], [2], [3], [4]
D0872		Ivosidenib	C28H22ClF3N6O3	71657455	Major		Inter Info	[115]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Major		Inter Info	[1], [2], [3], [4]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Major		Inter Info	[1], [2], [3], [4]
D0899		Lefamulin	C28H45NO5S	25185057	Major		Inter Info	[1], [2], [3], [4]
D0903		Lenvatinib	C21H19ClN4O4	9823820	Major		Inter Info	[1], [2], [3], [4]
D0909		Levacetylmethadol	C23H31NO2	15130	Major		Inter Info	[3], [116], [24]
D0919		Levofloxacin	C18H20FN3O4	149096	Major		Inter Info	[1], [2], [3], [4]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Major		Inter Info	[1], [2], [3], [4]
D0940		Lithium carbonate	CLi2O3	11125	Major		Inter Info	[2], [3], [4]
D0942		Lofexidine	C11H12Cl2N2O	30668	Major		Inter Info	[1], [2], [3], [4]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Major		Inter Info	[1], [2], [3], [4]
D0948		Lopinavir	C37H48N4O5	92727	Major		Inter Info	[2], [3], [4]
D0960		Lumefantrine	C30H32Cl3NO	6437380	Major		Inter Info	[2], [3], [117]
D0965		Macimorelin	C26H30N6O3	9804938	Major		Inter Info	[118]
D0979		Maprotiline	C20H23N	4011	Major		Inter Info	[1], [2], [3], [4]
D0992		Mefloquine	C17H16F6N2O	4046	Major		Inter Info	[1], [2], [3], [4]
D1010		Mesoridazine	C21H26N2OS2	4078	Major		Inter Info	[1], [2], [3], [119], [24]
D1017		Methadone	C21H27NO	4095	Major		Inter Info	[1], [2], [3], [4]
D1026		Methotrimeprazine	C19H24N2OS	72287	Major		Inter Info	[1], [2], [3], [4]
D1062		Midostaurin	C35H30N4O4	9829523	Major		Inter Info	[1], [2], [3], [4]
D1063		Mifepristone	C29H35NO2	55245	Major		Inter Info	[1], [2], [3], [120]
D1075		Mirtazapine	C17H19N3	4205	Major		Inter Info	[1], [2], [3], [4]
D1136		Nilotinib	C28H22F3N7O	644241	Major		Inter Info	[1], [2], [3], [121]
D1137		Nilutamide	C12H10F3N3O4	4493	Major		Inter Info	[1], [2], [3], [4]
D1155		Norfloxacin	C16H18FN3O3	4539	Major		Inter Info	[1], [2], [3], [4]
D1158		Nortriptyline	C19H21N	4543	Major		Inter Info	[1], [2], [3], [4]
D1165		Ofloxacin	C18H20FN3O4	4583	Major		Inter Info	[1], [2], [3], [4]
D1169		Oliceridine	C22H30N2O2S	66553195	Major		Inter Info	[1], [2], [3], [4]
D1181		Ondansetron	C18H19N3O	4595	Major		Inter Info	[1], [2], [3], [4]
D1189		Osilodrostat	C13H10FN3	44139752	Major		Inter Info	[1], [2], [3], [4]
D1190		Osimertinib	C28H33N7O2	71496458	Major		Inter Info	[1], [2], [3], [4]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Major		Inter Info	[1], [2], [3], [4]
D1215		Paliperidone	C23H27FN4O3	115237	Major		Inter Info	[1], [2], [3], [4]
D1216		Palonosetron	C19H24N2O	6337614	Major		Inter Info	[1], [2], [3], [4]
D1221		Panobinostat	C21H23N3O2	6918837	Major		Inter Info	[124]
D1223		Papaverine	C20H21NO4	4680	Major		Inter Info	[125], [126], [127], [128], [129], [130], [131], [132]
D1230		Pasireotide	C58H66N10O9	9941444	Major		Inter Info	[1], [2], [3], [4]
D1232		Pazopanib	C21H23N7O2S	10113978	Major		Inter Info	[1], [2], [3], [4]
D1246		Pentamidine	C19H24N4O2	4735	Major		Inter Info	[1], [2], [3], [4]
D1254		Perflutren	C3F8	6432	Major		Inter Info	[133], [134]
D1257		Perphenazine	C21H26ClN3OS	4748	Major		Inter Info	[1], [2], [3], [4]
D1290		Pimavanserin	C25H34FN3O2	10071196	Major		Inter Info	[1], [2], [3], [4]
D1292		Pimozide	C28H29F2N3O	16362	Major		Inter Info	[3], [135], [136], [24]
D1302		Pitolisant	C17H26ClNO	9948102	Major		Inter Info	[1], [2], [3], [4]
D1315		Posaconazole	C37H42F2N8O4	468595	Major		Inter Info	[1], [2], [3], [4]
D1339		Primaquine	C15H21N3O	4908	Major		Inter Info	[1], [2], [3], [4]
D1342		Probucol	C31H48O2S2	4912	Major		Inter Info	[1], [2], [3], [4]
D1343		Procainamide	C13H21N3O	4913	Major		Inter Info	[1], [2], [3], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D1346		Prochlorperazine	C20H24ClN3S	4917	Major		Inter Info	[1], [2], [3], [4]
D1351		Promazine	C17H20N2S	4926	Major		Inter Info	[1], [2], [3], [4]
D1352		Promethazine	C17H20N2S	4927	Major		Inter Info	[1], [2], [3], [4]
D1353		Propafenone	C21H27NO3	4932	Major		Inter Info	[1], [2], [3], [4]
D1361		Protriptyline	C19H21N	4976	Major		Inter Info	[1], [2], [3], [4]
D1368		Quetiapine	C21H25N3O2S	5002	Major		Inter Info	[1], [2], [3], [4]
D1371		Quinidine	C20H24N2O2	441074	Major		Inter Info	[1], [2], [3], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D1372		Quinine	C20H24N2O2	3034034	Major		Inter Info	[1], [2], [3], [4]
D1398		Ribociclib	C23H30N8O	44631912	Major		Inter Info	[1], [2], [3], [4]
D1404		Rilpivirine	C22H18N6	6451164	Major		Inter Info	[1], [2], [3], [4]
D1413		Risperidone	C23H27FN4O2	5073	Major		Inter Info	[1], [2], [3], [4]
D1424		Romidepsin	C24H36N4O6S2	5352062	Major		Inter Info	[1], [2], [3], [4]
D1432		Rucaparib	C19H18FN3O	9931954	Major		Inter Info	[1], [2], [3], [4]
D1444		Saquinavir	C38H50N6O5	441243	Major		Inter Info	[167], [168], [1], [2], [3], [169], [170]
D1459		Selpercatinib	C29H31N7O3	134436906	Major		Inter Info	[1], [2], [3], [4]
D1461		Sertraline	C17H17Cl2N	68617	Major		Inter Info	[1], [2], [3], [4]
D1463		Sevoflurane	C4H3F7O	5206	Major		Inter Info	[1], [2], [3], [4]
D1491		Solifenacin	C23H26N2O2	154059	Major		Inter Info	[1], [2], [3], [4]
D1497		Sorafenib	C21H16ClF3N4O3	216239	Major		Inter Info	[1], [2], [3], [4]
D1498		Sotalol	C12H20N2O3S	5253	Major		Inter Info	[1], [2], [3], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Major		Inter Info	[74], [1], [2], [3], [172], [173], [78], [80], [82], [174], [83], [84], [175], [86], [87], [88], [89], [176], [93], [98], [177]
D1522		Sunitinib	C22H27FN4O2	5329102	Major		Inter Info	[1], [2], [3], [4]
D1526		Tacrolimus	C44H69NO12	445643	Major		Inter Info	[1], [2], [3], [4]
D1533		Tamoxifen	C26H29NO	2733526	Major		Inter Info	[1], [2], [3], [4]
D1542		Telavancin	C80H106Cl2N11O27P	3081362	Major		Inter Info	[1], [2], [3], [4]
D1544		Telithromycin	C43H65N5O10	3002190	Major		Inter Info	[1], [2], [3], [4]
D1555		Terfenadine	C32H41NO2	5405	Major		Inter Info	[1], [2], [3], [4]
D1560		Tetrabenazine	C19H27NO3	6018	Major		Inter Info	[1], [2], [3], [4]
D1574		Thioridazine	C21H26N2S2	5452	Major		Inter Info	[1], [2], [3], [178], [135], [179], [180], [181], [24]
D1612		Toremifene	C26H28ClNO	3005573	Major		Inter Info	[1], [2], [3], [140]
D1624		Trazodone	C19H22ClN5O	5533	Major		Inter Info	[1], [2], [3], [4]
D1634		Triclabendazole	C14H9Cl3N2OS	50248	Major		Inter Info	[1], [2], [3], [4]
D1637		Trifluoperazine	C21H24F3N3S	5566	Major		Inter Info	[1], [2], [3], [4]
D1638		Triflupromazine	C18H19F3N2S	5568	Major		Inter Info	[1], [2], [3], [4]
D1647		Trimipramine	C20H26N2	5584	Major		Inter Info	[1], [2], [3], [4]
D1651		Triptorelin	C64H82N18O13	25074470	Major		Inter Info	[1], [2], [3], [4]
D1673		Valbenazine	C24H38N2O4	24795069	Major		Inter Info	[1], [2], [3], [4]
D1681		Vandetanib	C22H24BrFN4O2	3081361	Major		Inter Info	[1], [2], [3], [191]
D1682		Vardenafil	C23H32N6O4S	135400189	Major		Inter Info	[1], [2], [3], [4]
D1689		Venlafaxine	C17H27NO2	5656	Major		Inter Info	[1], [2], [3], [4]
D1706		Voriconazole	C16H14F3N5O	71616	Major		Inter Info	[1], [2], [3], [4]
D0139		Azithromycin	C38H72N2O12	447043	Major		Inter Info	[1], [2], [3], [4]
D0345		Citalopram	C20H21FN2O	2771	Major		Inter Info	[1], [2], [3], [193], [194], [24], [72]
D0513		Dofetilide	C19H27N3O5S2	71329	Major		Inter Info	[1], [2], [3], [195]
D0597		Erythromycin	C37H67NO13	12560	Major		Inter Info	[1], [2], [3], [4]
D0667		Fluconazole	C13H12F2N6O	3365	Major		Inter Info	[1], [2], [3], [4]
D0737		Goserelin	C59H84N18O14	5311128	Major		Inter Info	[1], [2], [3], [4]
D0908		Leuprolide	C59H84N16O12	657181	Major		Inter Info	[1], [2], [3], [4]
D1092		Moxifloxacin	C21H24FN3O4	152946	Major		Inter Info	[73], [74], [75], [1], [2], [3], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95]
D1210		Oxytocin	C43H66N12O12S2	439302	Major		Inter Info	[1], [2], [3], [4]
D1383		Ranolazine	C24H33N3O4	56959	Major		Inter Info	[1], [2], [3], [4]
D1616		Tramadol	C16H25NO2	33741	Major		Inter Info	[1], [2], [3], [4]
D1683		Vasopressin	C46H65N15O12S2	644077	Major		Inter Info	[1], [2], [3], [4]
D1726		Ziprasidone	C21H21ClN4OS	60854	Major		Inter Info	[1], [2], [3], [135], [200], [24]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[2], [3], [206], [207], [208], [209], [210], [211]
D0636		Famotidine	C8H15N7O2S3	5702160	Moderate		Inter Info	[2], [3], [262]
D0947		Loperamide	C29H33ClN2O2	3955	Moderate		Inter Info	[265], [266]
D1356		Propofol	C12H18O	4943	Moderate		Inter Info	[293], [294], [295], [296], [297], [298], [299], [300], [301], [302]
D1051		Metronidazole	C6H9N3O3	4173	Minor		Inter Info	[2], [318], [319], [320]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Minor		Inter Info	[1], [2], [3], [321], [322], [323], [324]
	Increased risk of ventricular arrhythmias					Drug Num: 37
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0025		Adenosine	C10H13N5O4	60961	Major		Inter Info	[8], [3], [9], [10], [11], [12], [13], [14]
D0107		Arsenic trioxide	As2O3	14888	Major		Inter Info	[36], [37]
D0661		Fingolimod	C19H33NO2	107970	Major		Inter Info	[1], [2], [3], [71], [72]
D0859		Isoprenaline	C11H17NO3	3779	Major		Inter Info	[110], [111], [112]
D0868		Ivabradine	C27H36N2O5	132999	Major		Inter Info	[3], [113], [114]
D1185		Orciprenaline	C11H17NO3	4086	Major		Inter Info	[110], [111], [112]
D1211		Ozanimod	C23H24N4O3	52938427	Major		Inter Info	[123]
D1414		Ritodrine	C17H21NO3	33572	Major		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [154], [155], [156], [157], [158], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D1474		Siponimod	C29H35F3N2O3	44599207	Major		Inter Info	[2], [171]
D1554		Terbutaline	C12H19NO3	5403	Major		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [154], [155], [156], [157], [158], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D0103		Arformoterol	C19H24N2O4	3083544	Moderate		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [203], [204], [154], [155], [156], [157], [158], [205], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D0269		Castor oil	C57H104O9	14030006	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D0516		Donepezil	C24H29NO3	3152	Moderate		Inter Info	[1], [2], [3], [256], [257], [258]
D0691		Formoterol	C19H24N2O4	3410	Moderate		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [203], [204], [154], [155], [156], [157], [158], [205], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D0701		Frangula purshiana bark	NA	NA	Moderate		Inter Info	[2], [3], [218]
D0707		Galantamine	C17H21NO3	9651	Moderate		Inter Info	[1], [2], [3], [256], [257], [258]
D0731		Glycerin	C3H8O3	753	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D0797		Indacaterol	C24H28N2O3	6918554	Moderate		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [203], [204], [154], [155], [156], [157], [158], [205], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D0887		Lactitol	C12H24O11	157355	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D0888		Lactulose	C12H22O11	11333	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D0924		Levosalbutamol	C13H21NO3	123600	Moderate		Inter Info	[203], [160], [163]
D0970		Magnesium citrate	C12H10Mg3O14	6099959	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D0973		Magnesium hydroxide	H2MgO2	14791	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D1069		Mineral oil	NA	NA	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D1171		Olodaterol	C21H26N2O5	11504295	Moderate		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [203], [204], [154], [155], [156], [157], [158], [205], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D1266		Phenolphthalein	C20H14O4	4764	Moderate		Inter Info	[1], [2], [3], [216], [217], [218]
D1287		Picosulfuric acid	C18H15NO8S2	5243	Moderate		Inter Info	[3], [290], [291]
D1298		Pirbuterol	C12H20N2O3	4845	Moderate		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [203], [204], [154], [155], [156], [157], [158], [205], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D1308		Polyethylene glycol (3350 with electrolytes)	C2H6O2	174	Moderate		Inter Info	[3], [290], [291]
D1309		Polyethylene glycol (3350)	C2H6O2	174	Moderate		Inter Info	[2], [3], [218]
D1418		Rivastigmine	C14H22N2O2	77991	Moderate		Inter Info	[1], [2], [3], [256], [257], [258]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[146], [152], [157]
D1440		Salmeterol	C25H37NO4	5152	Moderate		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [203], [204], [154], [155], [156], [157], [158], [205], [159], [111], [160], [161], [162], [163], [112], [164], [165]
D1488		Sodium sulfate	Na2O4S	24436	Moderate		Inter Info	[3], [290], [291]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[2], [3], [310]
D1695		Vilanterol	C24H33Cl2NO5	10184665	Moderate		Inter Info	[203], [160], [163]
D0854		Isoetharine	C13H21NO3	3762	Moderate		Inter Info	[110], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [153], [203], [204], [154], [155], [156], [157], [158], [205], [159], [111], [160], [161], [162], [163], [112], [164], [165]

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189	Product Information. Zanaflex (tizanidine). Acorda Therapeutics, Hawthorne, NY.
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195	Product Information. Tikosyn (dofetilide) Pfizer US Pharmaceuticals, Atlanta, GA.
196	Product Information. Xigris (drotrecogin alfa). Lilly, Eli and Company, Indianapolis, IN.
197	Product Information. In-111 Zevalin (ibritumomab). IDEC Pharmaceuticals Corporation, San Diego, CA.
198	Product Information. Bexxar I 131 Therapeutic (iodine I 131 tositumomab). GlaxoSmithKline, Research Triangle Park, NC.
199	Product Information. BexxarTherapy (tositumomab). GlaxoSmithKline Inc, Oakville, IA.
200	Product Information. Geodon (ziprasidone). Pfizer US Pharmaceuticals, New York, NY.
201	Product Information. Xeglyze (abametapir topical). Dr. Reddy's Laboratories Inc, Upper Saddle River, NJ.
202	Product Information. Lotronex (alosetron). Glaxo Wellcome, Research Triangle Park, NC.
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214	Product Information. Nevanac (nepafenac ophthalmic). Alcon Laboratories Inc, Fort Worth, TX.
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240	Product Information. Cymbalta (duloxetine). Lilly, Eli and Company, Indianapolis, IN.
241	Product Information. Effexor (venlafaxine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
242	Product Information. Fetzima (levomilnacipran). Forest Pharmaceuticals, St. Louis, MO.
243	Product Information. Luvox (fluvoxamine). Solvay Pharmaceuticals Inc, Marietta, GA.
244	Product Information. Paxil (paroxetine). GlaxoSmithKline, Research Triangle Park, NC.
245	Product Information. Pristiq (desvenlafaxine). Wyeth Laboratories, Philadelphia, PA.
246	Product Information. Prozac (fluoxetine). Dista Products Company, Indianapolis, IN.
247	Product Information. Savella (milnacipran). Forest Pharmaceuticals, St. Louis, MO.
248	Product Information. Viibryd (vilazodone). Trovis Pharmaceuticals LLC, New Haven, CT.
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259	Product Information. Flolan (epoprostenol). Glaxo Wellcome, Research Triangle Park, NC.
260	Product Information. Remodulin (treprostinil). United Therapeutics Corp, Silver Spring, MD.
261	Product Information. Ventavis (iloprost). Actelion Pharmaceuticals US Inc, South San Francisco, CA.
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263	Product Information. Panhematin (hemin). Recordati Rare Diseases Inc, Lebanon, NJ.
264	Product Information. Chirocaine (levobupivacaine) Organon, West Orange, NJ.
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268	Product Information. Zejula (niraparib). Tesaro Inc., Waltham, MA.
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281	Product Information. Lybalvi (olanzapine-samidorphan). Alkermes, Inc, Cambridge, MA.
282	Product Information. Qelbree (viloxazine). Supernus Pharmaceuticals Inc, Rockville, MD.
283	Product Information. Zyprexa (olanzapine). Lilly, Eli and Company, Indianapolis, IN.
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287	Product Information. Vascepa (icosapent). Amarin Pharmaceuticals Inc, Warren, NJ.
288	Product Information. Elmiron (pentosan polysulfate sodium). Baker Norton Pharmaceuticals, Miami, FL.
289	Product Information. Trental (pentoxifylline). Hoechst Marion-Roussel Inc, Kansas City, MO.
290	Product Information. Suclear (polyethylene glycol 3350 with electrolytes). Braintree Laboratories, Braintree, MA.
291	Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates). Braintree Laboratories, Braintree, MA.
292	Product Information. Esbriet (pirfenidone). Intermune Inc, Brisbane, CA.
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303	Product Information. Rozerem (ramelteon). Takeda Pharmaceuticals America, Lincolnshire, IL.
304	Product Information. Daliresp (roflumilast). Astra-Zeneca Pharmaceuticals, Wilmington, DE.
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306	Product Information. Noroxin (norfloxacin). Merck & Co, Inc, West Point, PA.
307	Product Information. Requip (ropinirole). SmithKline Beecham, Philadelphia, PA.
308	Product Information. Diacomit (stiripentol). Biocodex Inc, Creswell, OR.
309	Product Information. Hetlioz (tasimelteon). Vanda Pharmaceuticals Inc, Rockville, MD.
310	Product Information. Thalomid (thalidomide). Celgene Corporation, Warren, NJ.
311	Product Information. Brilinta (ticagrelor). Astra-Zeneca Pharmaceuticals, Wilmington, DE.
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