Details of Drug

Details of Drug

 Drug General Information (ID: D1777)
  Drug Name
Dinoprostone (topical)
  Drug Type Small molecule
  Drug Synonymous
Cervidil; Dinoproston; Dinoprostona; Dinoprostonum; Prepidil; Propess; Prostenon; Prostin; Prepidil Gel; Prostarmon E;Prostin E; Dinoprostone Prostaglandin E2; Minprositin E2; Minprostin E2; PGE2; PGE2 alpha; PGE2alpha; Prostaglandin E2; Prostaglandin E2 alpha; Prostaglandin E2alpha; Prostarmon E2; Prostin E2; U 12062; [3H]PGE2; Alpha, PGE2; Alpha, Prostaglandin E2; BML1-F07; Cervidil (TN); Dinoprostona [INN-Spanish]; Dinoprostone beta-Cyclodextrin Clathrate; Dinoprostonum [INN-Latin]; E2 alpha, Prostaglandin; E2, Prostaglandin; E2alpha, Prostaglandin; Gel, Prepidil; L-PGE2; L-Prostaglandin E2; Prepidil (TN); Propess (TN); Prostin E2 (TN); U-12062; BMS-279654 & PGE2; Dinoprostone (JAN/USP/INN); Dinoprostone [USAN:INN:BAN:JAN]; L-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid; (15S)-Prostaglandin E2; (5Z,11-alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; (5Z,11.alpha.,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic; (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid; (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate; (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate; (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid; (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid; 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-(8CI); 7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
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  Disease Class JA00: Abortion
  Therapeutic Class Prostaglandins
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C20H32O5
  InChI 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1
  InChIKey XEYBRNLFEZDVAW-ARSRFYASSA-N
  Canonical SMILES CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O
  External Link
Pubchem ID 5280360
CAS Number CAS 363-24-6
CHEBI ID CHEBI:15551
TTD ID D06FEA
INTEDE ID DR0511
VARIDT ID DR00102

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM083  Potentiated the pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Dinoprostone (topical)
      Pharmacodynamic additive effects
   Potentiated the pharmacological effects (Unspecific) Drug Num:  6
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0592
 
Ergometrine
 
C19H23N3O2
 
443884 
Major    Inter Info   
[1], [2]
D1076
 
Misoprostol
 
C22H38O5
 
5282381 
Major    Inter Info   
[1], [2]
D1668
 
Urea
 
CH4N2O
 
1176 
Major    Inter Info   
[1], [2]
D1037
 
Methylergometrine
 
C20H25N3O2
 
8226 
Major    Inter Info   
[1], [2]
D1063
 
Mifepristone
 
C29H35NO2
 
55245 
Major    Inter Info   
[1], [2]
D1210
 
Oxytocin
 
C43H66N12O12S2
 
439302 
Major    Inter Info   
[3], [4], [1]
References
1 Product Information. Prostin E2 (dinoprostone topical). Pharmacia and Upjohn, Kalamazoo, MI.
2 Product Information. Prostin E2 Suppository (dinoprostone topical). Pharmacia and Upjohn, Kalamazoo, MI.
3 Product Information. Prepidil (dinoprostone topical) Pharmacia and Upjohn, Kalamazoo, MI.
4 Product Information. Cervidil (dinoprostone topical). Forest Pharmaceuticals, St. Louis, MO.