Details of Drug

Drug General Information (ID: D1734)
Drug Name	Agalsidase beta
Drug Type	Protein/peptide
Drug Synonymous	Fabrazyme (TN) Click to Show/Hide
Disease Class	5C50-5D2Z: Metabolic disorder
Therapeutic Class	Metabolic Agents
Structure
Structure	3D Structure		2D Structure
Formula	C50H78N4O14
InChI	1S/2C23H36N2O4.C4H6O6/c21-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20;5-1(3(7)8)2(6)4(9)10/h210-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26);1-2,5-6H,(H,7,8)(H,9,10)/t2*19-,23-;1-,2-/m111/s1
InChIKey	KUBARPMUNHKBIQ-VTHUDJRQSA-N
Canonical SMILES	CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.C(C(C(=O)O)O)(C(=O)O)O
External Link
	Pubchem ID	52918379
	CAS Number	CAS 928659-70-5
	CHEBI ID	CHEBI:83353
	TTD ID	D0J8IJ
	INTEDE ID	DR0567
	VARIDT ID	DR00220

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM083 Potentiated the pharmacological effects (Unspecific) BM107 Attenuated pharmacological effects (Unspecific)
Relation Graph

Full list of drugs interacting with Agalsidase beta
Pharmacodynamic additive effects
	Potentiated the pharmacological effects (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1846		Migalastat	C6H13NO4	176077	Moderate		Inter Info	[2], [3]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0066		Amiodarone	C25H29I2NO3	2157	Major		Inter Info	[1]
D0320		Chloroquine	C18H26ClN3	2719	Major		Inter Info	[1]
D0718		Gentamicin	C21H43N5O7	3467	Major		Inter Info	[1]

References
1	Product Information. Replagal (agalsidase alfa). Transkaryotic Therapies Inc, Cambridge, MA.
2	Canadian Pharmacists Association.
3	Product Information. Galafold (migalastat). Amicus Therapeutics U.S., Inc., Cranbury, NJ.