Details of Drug

Drug General Information (ID: D1011)
Drug Name	Mestranol
Drug Type	Small molecule
Drug Synonymous	Devocin; Menophase; Mestranolo; Mestranolum; Norquen; Ovastol; Component of Norinyl; Component of Norquen; Component of Ovulen; Ethynylestradiol methyl ether; Mestranol [Steroidal oestrogens]; Mestranolo [DCIT]; EE3ME; Ethinyl Estradiol 3 Methyl Ether; SC 4725; Component of Ortho-Novum; Delta-MVE; EE(sub3)ME; EthinylEstradiol 3-Methyl Ether; Ethinylestradiol 3-methyl ether; Ethinyloestradiol 3-methyl ether; Ethynylestradiol 3-methyl ether; Ethynyloestradiol 3-methyl ether; Inostral (steroid); Mestranolum [INN-Latin]; Mestranol (JP15/USP/INN); Mestranol [USAN:INN:BAN:JAN]; Alpha.-19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-meth; (17beta)-17-ethynyl-3-(methyloxy)estra-1,3,5(10)-trien-17-ol; 17-Ethynyl-3-methoxy-1,3,5(10)-oestratien-17-beta-ol; 17-Ethynyl-3-methoxyestra-1,3,5(10)-trien-17-ol; 17-Ethynylestradiol 3-methyl ether; 17-Ethynyloestradiol 3-methyl ether; 17-alpha-Ethinyl estradiol 3-methyl ether; 17-alpha-Ethinyl oestradiol 3-methyl ether; 17-alpha-Ethynyl-3-methoxy-1,3,5(10)-estratrien-17-beta-ol; 17-alpha-Ethynyloestradiol methyl ether; 17-ethynyl-3-methoxyestra-1(10),2,4-trien-17beta-ol; 17-ethynyl-3-methoxyoestra-1(10),2,4-trien-17beta-ol; 17alpha-Ethinyl estradiol 3-methyl ether; 17alpha-Ethinyl oestradiol 3-methyl ether; 17alpha-Ethinylestradiol 3-methyl ether; 17alpha-Ethynylestradiol 3-methyl ether; 17alpha-Ethynylestradiol methyl ether; 17alpha-Ethynyloestradiol 3-methyl ether; 17beta-Estradiol, 17-ethynyl-, 3-(methyl ether); 3-Methoxy-17-alpha-19-norpregna-1,3,5(10)-trien-20-yn-17-ol; 3-Methoxy-17-alpha-ethinylestradiol; 3-Methoxy-17-alpha-ethinyloestradiol; 3-Methoxy-17-alpha-ethynyl-1,3,5(10)-estratrien-17-beta-ol; 3-Methoxy-17-alpha-ethynyl-1,3,5(10)-oestratrien-17-beta-ol; 3-Methoxy-17-alpha-ethynylestradiol; 3-Methoxy-17-alpha-ethynyloestradiol; 3-Methoxy-17-ethynyloestradiol-17-beta; 3-Methoxy-17alpha-ethinylestradiol; 3-Methoxy-17alpha-ethinyloestradiol; 3-Methoxy-17alpha-ethynyl-1,3,5(10)-estratrien-17beta-ol; 3-Methoxy-17alpha-ethynyl-1,3,5(10)-oestratrien-17beta-ol; 3-Methoxy-17alpha-ethynylestradiol; 3-Methoxy-17alpha-ethynyloestradiol; 3-Methoxy-19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yn-17-ol; 3-Methoxy-19-nor-17alpha-pregna-1,3,5(10)-trien-20-yn-17-ol; 3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17beta-ol; 3-Methoxyethynylestradiol; 3-Methoxyethynyloestradiol; 3-Methylethynylestradiol; 3-Methylethynyloestradiol; 3-O-Methylethynylestradiol Click to Show/Hide
Disease Class	QA21: Contraceptive management
Therapeutic Class	Estrogens
Structure
Structure	3D Structure		2D Structure
Formula	C21H26O2
InChI	1S/C21H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3/t17-,18-,19+,20+,21+/m1/s1
InChIKey	IMSSROKUHAOUJS-MJCUULBUSA-N
Canonical SMILES	CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)OC
External Link
	Pubchem ID	6291
	CAS Number	72-33-3
	CHEBI ID	6784
	TTD ID	D0J1ML
	INTEDE ID	DR1034

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM003 Affected organization distribution AM004 Affected intra/extra-hepatic metabolism AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM003 Complex formation BM009 Altered absorption (Unspecific) BM015 Increase globulin concentration BM016 Altered formation of CYP450 enzymes BM017 CYP450 enzyme inhibition BM019 UGT inhibition BM022 CYP450 enzyme induction BM023 UGT induction BM025 Decreased metabolism (Unspecific) BM031 Increased renal excretion (Unspecific) BM047 Additive thrombogenic effects BM055 Increased risk of hepatotoxicity BM079 Increased risk of skin rash BM085 Antagonize the effect of antithrombotic agents BM086 Antagonize the effect of antidiabetic agents BM094 Antagonize the effect of estrogen BM107 Attenuated pharmacological effects (Unspecific)
Relation Graph

Full list of drugs interacting with Mestranol
Affected gastrointestinal absorption
	Complex formation					Drug Num: 23
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0277		Cefdinir	C14H13N5O5S2	6915944	Moderate		Inter Info	[27], [40], [28]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[41], [42], [43]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[41], [42], [43]
D0381		Colesevelam	C31H67Cl3N4O	160051	Moderate		Inter Info	[35], [6], [44]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[41], [42], [43]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[41], [42], [43]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[41], [42], [43]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[41], [42], [43]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[41], [42], [43]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[41], [42], [43]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[41], [42], [43]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[41], [42], [43]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[41], [42], [43]
D1175		Omadacycline	C29H40N4O7	54697325	Moderate		Inter Info	[41], [42], [43]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[41], [42], [43]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[41], [42], [43]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[41], [42], [43]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[41], [42], [43]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[41], [42], [43]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[41], [42], [43]
D1209		Oxytetracycline	C22H24N2O9	54675779	Moderate		Inter Info	[41], [42], [43]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[41], [42], [43]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[41], [42], [43]
	Altered absorption (Unspecific)					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0929		Linaclotide	C59H79N15O21S6	16158208	Moderate		Inter Info	[11], [62], [63]
D1362		Prucalopride	C18H26ClN3O3	3052762	Moderate		Inter Info	[48], [11], [65]
Affected organization distribution
	Increase globulin concentration					Drug Num: 17
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[37], [38], [39]
D0215		Budesonide	C25H34O6	5281004	Moderate		Inter Info	[37], [38], [39]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[37], [38], [39]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[37], [38], [39]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[37], [38], [39]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[37], [38], [39]
D0925		Levothyroxine	C15H11I4NO4	5819	Moderate		Inter Info	[54], [55], [56]
D0934		Liothyronine	C15H12I3NO4	5920	Moderate		Inter Info	[54], [55], [56]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[37], [38], [39]
D0935		Liotrix	C30H21I7N2Na2O8	71371	Moderate		Inter Info	[54], [55], [56]
D1577		Thyroid, porcine	NA	NA	Moderate		Inter Info	[54], [55], [56]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[37], [38], [39]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[37], [38], [39]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[37], [38], [39]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[37], [38], [39]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[37], [38], [39]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[37], [38], [39]
Affected intra/extra-hepatic metabolism
	Altered formation of CYP450 enzymes					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0023		Adalimumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0032		Alefacept	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0085		Anakinra	C20H23N5O7S2	146171046	Moderate		Inter Info	[23], [24], [25]
D0304		Certolizumab pegol	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0564		Emapalumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1403		Rilonacept	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1447		Sarilumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1454		Secukinumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1467		Siltuximab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1599		Tocilizumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1671		Ustekinumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
	CYP450 enzyme inhibition					Drug Num: 10
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[35], [6], [36]
D0386		Conivaptan	C32H26N4O2	151171	Moderate		Inter Info	[6], [45]
D0426		Darunavir	C27H37N3O7S	213039	Moderate		Inter Info	[46], [47]
D0642		Fenofibrate	C20H21ClO4	3339	Moderate		Inter Info	[48], [11], [49]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[48], [11], [50]
D1117		Nefazodone	C25H32ClN5O2	4449	Moderate		Inter Info	[67], [68], [69]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[72], [69], [73]
D0439		Delavirdine	C22H28N6O3S	5625	Minor		Inter Info	[90], [91], [92]
D0799		Indinavir	C36H47N5O4	5362440	Minor		Inter Info	[94], [95]
D0994		Melatonin	C13H16N2O2	896	Minor		Inter Info	[48], [47], [99]
	CYP450 enzyme induction					Drug Num: 10
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0178		Bexarotene	C24H28O2	82146	Major		Inter Info	[1], [2], [3]
D0194		Bosentan	C27H29N5O6S	104865	Major		Inter Info	[1], [4], [3]
D0639		Felbamate	C11H14N2O4	3331	Major		Inter Info	[8], [9], [10]
D0697		Fosphenytoin	C16H15N2O6P	56339	Major		Inter Info	[8], [9], [10]
D0044		Alpelisib	C19H22F3N5O2S	56649450	Moderate		Inter Info	[5], [6], [57]
D0432		Deferasirox	C21H15N3O4	214348	Moderate		Inter Info	[6], [61]
D1128		Nevirapine	C15H14N4O	4463	Moderate		Inter Info	[70], [1], [71]
D1609		Topiramate	C12H21NO8S	5284627	Moderate		Inter Info	[76], [77], [51]
D1652		Troglitazone	C24H27NO5S	5591	Moderate		Inter Info	[78], [79], [80]
D1294		Pioglitazone	C19H20N2O3S	4829	Minor		Inter Info	[78], [102], [103]
	UGT induction					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0011		Acetaminophen	C8H9NO2	1983	Minor		Inter Info	[81], [82], [83]
D0951		Lorazepam	C15H10Cl2N2O2	3958	Minor		Inter Info	[96], [97], [98]
D1197		Oxazepam	C15H11ClN2O2	4616	Minor		Inter Info	[96], [97], [98]
D1547		Temazepam	C16H13ClN2O2	5391	Minor		Inter Info	[96], [97], [98]
	Decreased metabolism (Unspecific)					Drug Num: 11
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0068		Amitriptyline	C20H23N	2160	Minor		Inter Info	[84], [85], [86]
D0072		Amoxapine	C17H16ClN3O	2170	Minor		Inter Info	[84], [85], [86]
D0337		Cimetidine	C10H16N6S	2756	Minor		Inter Info	[87], [88], [89]
D0361		Clomipramine	C19H23ClN2	2801	Minor		Inter Info	[84], [85], [86]
D0446		Desipramine	C18H22N2	2995	Minor		Inter Info	[84], [85], [86]
D0525		Doxepin	C19H21NO	667477	Minor		Inter Info	[84], [85], [86]
D0526		Doxepin (topical)	C19H21NO	667477	Minor		Inter Info	[84], [85], [86]
D0795		Imipramine	C19H24N2	3696	Minor		Inter Info	[84], [85], [86]
D1158		Nortriptyline	C19H21N	4543	Minor		Inter Info	[84], [85], [86]
D1361		Protriptyline	C19H21N	4976	Minor		Inter Info	[84], [85], [86]
D1647		Trimipramine	C20H26N2	5584	Minor		Inter Info	[84], [85], [86]
Affected excretion pathways
	Increased renal excretion (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0489		Diflunisal	C13H8F2O3	3059	Minor		Inter Info	[5], [6], [93]
Pharmacodynamic additive effects
	Additive thrombogenic effects					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0902		Lenalidomide	C13H13N3O3	216326	Major		Inter Info	[11], [6], [12]
D0261		Carfilzomib	C40H57N5O7	11556711	Major		Inter Info	[1], [11]
D1312		Pomalidomide	C13H11N3O4	134780	Major		Inter Info	[14], [15], [16]
D1569		Thalidomide	C13H10N2O4	5426	Major		Inter Info	[11], [6], [19]
D0385		Conestat alfa	NA	NA	Moderate		Inter Info	[58], [59], [60]
D0762		Human C1-esterase inhibitor	NA	NA	Moderate		Inter Info	[58], [59], [60]
	Increased risk of hepatotoxicity					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0417		Dantrolene	C14H10N4O5	6914273	Major		Inter Info	[5], [6], [7]
	Increased risk of skin rash					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1592		Tipranavir	C31H33F3N2O5S	54682461	Moderate		Inter Info	[74], [75]
Pharmacodynamic antagonistic effects
	Antagonize the effect of antithrombotic agents					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0087		Anisindione	C16H12O3	2197	Moderate		Inter Info	[32], [33], [34]
D0481		Dicoumarol	C19H12O6	54676038	Moderate		Inter Info	[32], [33], [34]
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[32], [33], [34]
	Antagonize the effect of antidiabetic agents					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0009		Acarbose	C25H43NO18	41774	Moderate		Inter Info	[20], [21], [22]
D0727		Glimepiride	C24H34N4O5S	3476	Moderate		Inter Info	[20], [21], [22]
D0808		Insulin aspart (aspart)	C256H381N65O79S6	118984445	Moderate		Inter Info	[20], [21], [22]
D1392		Repaglinide	C27H36N2O4	65981	Moderate		Inter Info	[20], [21], [22]
D1477		Sitagliptin	C16H15F6N5O	4369359	Moderate		Inter Info	[20], [21], [22]
	Antagonize the effect of estrogen					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[5], [6], [66]
D1885		Saw palmetto	NA	NA	Minor		Inter Info	[101], [47], [99]
	Attenuated pharmacological effects (Unspecific)					Drug Num: 90
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0752		Hemin	C34H32FeN4O4	26945	Major		Inter Info	[13]
D1095		Mycophenolic acid	C17H20O6	446541	Major		Inter Info	[6], [17], [18]
D0056		Amikacin	C22H43N5O13	37768	Moderate		Inter Info	[26], [27], [28]
D0057		Amikacin (liposome)	C22H43N5O13	37768	Moderate		Inter Info	[26], [27], [28]
D0073		Amoxicillin	C16H19N3O5S	33613	Moderate		Inter Info	[26], [27], [28]
D0079		Ampicillin	C16H19N3O4S	6249	Moderate		Inter Info	[26], [27], [28]
D0086		Anastrozole	C17H19N5	2187	Moderate		Inter Info	[29], [30], [31]
D0139		Azithromycin	C38H72N2O12	447043	Moderate		Inter Info	[26], [27], [28]
D0140		Aztreonam	C13H17N5O8S2	5742832	Moderate		Inter Info	[26], [27], [28]
D0142		Bacitracin	C66H103N17O16S	10909430	Moderate		Inter Info	[26], [27], [28]
D0167		Benzylpenicillin	C16H18N2O4S	5904	Moderate		Inter Info	[26], [27], [28]
D0168		Benzylpenicillin (potassium)	C16H18N2O4S	5904	Moderate		Inter Info	[26], [27], [28]
D0169		Benzylpenicillin (sodium)	C16H18N2O4S	5904	Moderate		Inter Info	[26], [27], [28]
D0257		Carbenicillin	C17H18N2O6S	20824	Moderate		Inter Info	[26], [27], [28]
D0271		Cefaclor	C15H14ClN3O4S	51039	Moderate		Inter Info	[26], [27], [28]
D0272		Cefadroxil	C16H17N3O5S	47965	Moderate		Inter Info	[26], [27], [28]
D0273		Cefalotin	C16H16N2O6S2	6024	Moderate		Inter Info	[26], [27], [28]
D0274		Cefamandole	C18H18N6O5S2	456255	Moderate		Inter Info	[26], [27], [28]
D0275		Cefapirin	C17H17N3O6S2	30699	Moderate		Inter Info	[26], [27], [28]
D0276		Cefazolin	C14H14N8O4S3	33255	Moderate		Inter Info	[26], [27], [28]
D0278		Cefditoren	C19H18N6O5S3	9870843	Moderate		Inter Info	[26], [27], [28]
D0281		Cefixime	C16H15N5O7S2	5362065	Moderate		Inter Info	[26], [27], [28]
D0282		Cefmetazole	C15H17N7O5S3	42008	Moderate		Inter Info	[26], [27], [28]
D0283		Cefonicid	C18H18N6O8S3	43594	Moderate		Inter Info	[26], [27], [28]
D0284		Cefoperazone	C25H27N9O8S2	44187	Moderate		Inter Info	[26], [27], [28]
D0285		Cefotaxime	C16H17N5O7S2	5742673	Moderate		Inter Info	[26], [27], [28]
D0286		Cefotetan	C17H17N7O8S4	53025	Moderate		Inter Info	[26], [27], [28]
D0287		Cefoxitin	C16H17N3O7S2	441199	Moderate		Inter Info	[26], [27], [28]
D0289		Cefprozil	C18H19N3O5S	5281006	Moderate		Inter Info	[26], [27], [28]
D0290		Cefradine	C16H19N3O4S	38103	Moderate		Inter Info	[26], [27], [28]
D0292		Ceftazidime	C22H22N6O7S2	5481173	Moderate		Inter Info	[26], [27], [28]
D0294		Ceftizoxime	C13H13N5O5S2	6533629	Moderate		Inter Info	[26], [27], [28]
D0296		Ceftriaxone	C18H18N8O7S3	5479530	Moderate		Inter Info	[26], [27], [28]
D0297		Cefuroxime	C16H16N4O8S	5479529	Moderate		Inter Info	[26], [27], [28]
D0301		Cephalexin	C16H17N3O4S	27447	Moderate		Inter Info	[26], [27], [28]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[26], [27], [28]
D0354		Clindamycin	C18H33ClN2O5S	446598	Moderate		Inter Info	[26], [27], [28]
D0369		Cloxacillin	C19H18ClN3O5S	6098	Moderate		Inter Info	[26], [27], [28]
D0383		Colistimethate	C58H105N16O28S5-5	70789202	Moderate		Inter Info	[26], [27], [28]
D0421		Daptomycin	C72H101N17O26	16134395	Moderate		Inter Info	[26], [27], [28]
D0480		Dicloxacillin	C19H17Cl2N3O5S	18381	Moderate		Inter Info	[26], [27], [28]
D0596		Ertapenem	C22H25N3O7S	150610	Moderate		Inter Info	[26], [27], [28]
D0630		Exemestane	C20H24O2	60198	Moderate		Inter Info	[29], [30], [31]
D0718		Gentamicin	C21H43N5O7	3467	Moderate		Inter Info	[26], [27], [28]
D0876		Kanamycin	C18H36N4O11	6032	Moderate		Inter Info	[26], [27], [28]
D0890		Lamotrigine	C9H7Cl2N5	3878	Moderate		Inter Info	[51], [52], [53]
D0907		Letrozole	C17H11N5	3902	Moderate		Inter Info	[29], [30], [31]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[26], [27], [28]
D0949		Loracarbef	C16H16ClN3O4	5284585	Moderate		Inter Info	[26], [27], [28]
D1008		Meropenem	C17H25N3O5S	441130	Moderate		Inter Info	[26], [27], [28]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[26], [27], [28]
D0279		Cefepime	C19H24N6O5S2	5479537	Moderate		Inter Info	[26], [27], [28]
D0280		Cefiderocol	C30H34ClN7O10S2	77843966	Moderate		Inter Info	[26], [27], [28]
D0288		Cefpodoxime	C15H17N5O6S2	6335986	Moderate		Inter Info	[26], [27], [28]
D0291		Ceftaroline fosamil	C22H21N8O8PS4	9852981	Moderate		Inter Info	[26], [27], [28]
D0293		Ceftibuten	C15H14N4O6S2	5282242	Moderate		Inter Info	[26], [27], [28]
D0411		Dalbavancin	C88H100Cl2N10O28	16134627	Moderate		Inter Info	[26], [27], [28]
D0519		Doripenem	C15H24N4O6S2	73303	Moderate		Inter Info	[26], [27], [28]
D0589		Eravacycline	C27H31FN4O8	54726192	Moderate		Inter Info	[26], [27], [28]
D0931		Lincomycin	C18H34N2O6S	3000540	Moderate		Inter Info	[26], [27], [28]
D1044		Meticillin	C17H20N2O6S	6087	Moderate		Inter Info	[26], [27], [28]
D1124		Neratinib	C30H29ClN6O3	9915743	Moderate		Inter Info	[64], [48]
D1228		Paromomycin	C23H45N5O14	165580	Moderate		Inter Info	[26], [27], [28]
D1304		Plazomicin	C25H48N6O10	42613186	Moderate		Inter Info	[26], [27], [28]
D1539		Tedizolid	C17H15FN6O3	11234049	Moderate		Inter Info	[26], [27], [28]
D1580		Ticarcillin	C15H16N2O6S2	36921	Moderate		Inter Info	[26], [27], [28]
D1653		Troleandomycin	C41H67NO15	202225	Moderate		Inter Info	[26], [27], [28]
D1051		Metronidazole	C6H9N3O3	4173	Moderate		Inter Info	[26], [27], [28]
D1055		Mezlocillin	C21H25N5O8S2	656511	Moderate		Inter Info	[26], [27], [28]
D1120		Neomycin	C23H46N6O13	8378	Moderate		Inter Info	[26], [27], [28]
D1126		Netilmicin	C21H41N5O7	441306	Moderate		Inter Info	[26], [27], [28]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Moderate		Inter Info	[26], [27], [28]
D1159		Novobiocin	C31H36N2O11	54675769	Moderate		Inter Info	[26], [27], [28]
D1192		Oxacillin	C19H19N3O5S	6196	Moderate		Inter Info	[26], [27], [28]
D1268		Phenoxymethylpenicillin	C16H18N2O5S	6869	Moderate		Inter Info	[26], [27], [28]
D1296		Piperacillin	C23H27N5O7S	43672	Moderate		Inter Info	[26], [27], [28]
D1310		Polymyxin B	C56H98N16O13	49800004	Moderate		Inter Info	[26], [27], [28]
D1507		Streptomycin	C21H39N7O12	19649	Moderate		Inter Info	[26], [27], [28]
D1513		Sulfadiazine	C10H10N4O2S	5215	Moderate		Inter Info	[26], [27], [28]
D1514		Sulfadoxine	C12H14N4O4S	17134	Moderate		Inter Info	[26], [27], [28]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Moderate		Inter Info	[26], [27], [28]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Moderate		Inter Info	[26], [27], [28]
D1517		Sulfasalazine	C18H14N4O5S	5339	Moderate		Inter Info	[26], [27], [28]
D1519		Sulfisoxazole	C11H13N3O3S	5344	Moderate		Inter Info	[26], [27], [28]
D1557		Testolactone	C19H24O3	13769	Moderate		Inter Info	[29], [30], [31]
D1582		Tigecycline	C29H39N5O8	54686904	Moderate		Inter Info	[26], [27], [28]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[26], [27], [28]
D1597		Tobramycin	C18H37N5O9	36294	Moderate		Inter Info	[26], [27], [28]
D1680		Vancomycin	C66H75Cl2N9O24	14969	Moderate		Inter Info	[26], [27], [28]
D1812		Hyaluronidase	C17H24BrNO2	91820602	Minor		Inter Info	[5], [6], [100]

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