Details of Drug

Details of Drug

 Drug General Information (ID: D0830)
  Drug Name
Iodide I-131
  Drug Type Small molecule
  Drug Synonymous
Iodide ion I-131; Iodide-131; iodine-131(1-); UNII-4GC1FOQ22U; 4GC1FOQ22U; 14914-30-8; Iodide (131I-); Radioiodine; Iodide, isotope of mass 131; Iodide I-131 ion; Iodide ion I 131; Iodide I-131; Iodide ion, I-131; (~131~I)Iodide; Iodide (131I1-); DTXSID70933558; DB09293; Q27259563
    Click to Show/Hide
  Therapeutic Class Radiopharmaceuticals
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula I-
  InChI InChI=1S/HI/h1H/p-1/i1+4
  InChIKey XMBWDFGMSWQBCA-RNFDNDRNSA-M
  Canonical SMILES [131I-]
  External Link
Pubchem ID 167195

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM014  Interference of cell/tissue uptake
BM043  Additive immunosuppressive effects
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Iodide I-131
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  5
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1783
 
Ethiodized oil
 
NA
 
NA
Moderate    Inter Info   
[4], [7], [8]
D1823
 
Iodine
 
I2
 
807 
Moderate    Inter Info   
[4], [7], [8]
D1824
 
Iodine (topical)
 
I2
 
807 
Moderate    Inter Info   
[4], [7], [8]
D0925
 
Levothyroxine
 
C15H11I4NO4
 
5819 
Moderate    Inter Info   
[11], [12], [13]
D0934
 
Liothyronine
 
C15H12I3NO4
 
5920 
Moderate    Inter Info   
[11], [12], [13]
      Pharmacodynamic additive effects
   Additive immunosuppressive effects Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0136
 
Azathioprine
 
C9H7N7O2S
 
2265 
Moderate    Inter Info   
[4], [5], [6]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0066
 
Amiodarone
 
C25H29I2NO3
 
2157 
Major    Inter Info   
[1], [2], [3]
D1871
 
Pyrantel
 
C11H14N2S
 
708857 
Moderate    Inter Info   
[9], [10], [7]
D1892
 
Sodium iodide
 
INa
 
5238 
Moderate    Inter Info   
[4], [7], [8]
References
1 Libersa CC, Brique SA, Motte KB, et al. "Dramatic inhibition of amiodarone metabolism induced by grapefruit juice." Br J Clin Pharmacol 49 (2000): 373-8. [PMID: 10759694]
2 Product Information. Cordarone Intravenous (amiodarone). Wyeth-Ayerst Laboratories, Philadelphia, PA.
3 Canadian Pharmacists Association "e-CPS."
4 Cerner Multum, Inc. "Australian Product Information.".
5 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
6 Product Information. Lonsurf (tipiracil-trifluridine). Taiho Oncology, Inc., Princeton, NJ.
7 Product Information. Sodium Iodide I-123 (sodium iodide I-123). GE Healthcare, Princeton, NJ.
8 Product Information. Visipaque (iodixanol). Nycomed Inc, Princeton, NJ.
9 Product Information. Rexulti (brexpiprazole). Otsuka American Pharmaceuticals Inc, Rockville, MD.
10 Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7. [PMID: 3725002]
11 EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
12 Lampe WT "Hypoglycemia due to acetohexamide." Arch Intern Med 120 (1967): 239-41. [PMID: 4952678]
13 Multum Information Services, Inc. Expert Review Panel.