Details of Drug

Drug General Information (ID: D0694)
Drug Name	Foscarnet
Drug Type	Small molecule
Drug Synonymous	foscarnet; Phosphonoformic acid; Phosphonoformate; Carboxyphosphonic acid; 4428-95-9; Foscarmet; phosphonocarboxylic acid; Dihydroxyphosphinecarboxylic acid oxide; UNII-364P9RVW4X; phosphonomethanoic acid; CHEMBL666; 364P9RVW4X; CHEBI:127780; dihydroxyphosphanecarboxylic acid oxide; Phgosphonocarboxylic acid; NSC313410; Formic acid, phosphono-; Forscarnet; Phosphinecarboxylic acid, dihydroxy-, oxide; HSDB 8122; 1nki; J05AD01; Foscarnet (PFA); Spectrum_001359; PFA & rIFN.alpha.A; Spectrum2_000668; Spectrum3_001484; Spectrum4_000840; Spectrum5_000932; phosphonoformic acid(PFA); MSL & PFA; Phosphono-formic acid(PFA); hydroxycarbonylphosphonic acid; SCHEMBL23633; BSPBio_003067; Foscarnet & IFN-.ALPHA.; KBioGR_001419; KBioSS_001839; DivK1c_000915; SPBio_000735; GTPL5497; DTXSID0048478; KBio1_000915; KBio2_001839; KBio2_004407; KBio2_006975; KBio3_002567; NINDS_000915; ZINC8101109; BDBM50011181; Phosphonoformic acid & IFN-.ALPHA.; AKOS006281397; DB00529; IDI1_000915; Phosphonoformic acid trisodium salt hexa; (PFA)dihydroxyphosphinecarboxylic acid oxide; dihydroxyphosphinecarboxylic acid oxide(PFA); C06456; Q420387; 6-(2-Nitrophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole; Phosphonoformate(trisodium) & Recombinant Alpha-A Interferon; Dihydroxyphosphinecarboxylic acid oxide and MSL, neutralizing monoclonal antibody Click to Show/Hide
Therapeutic Class	Antiviral Agents
Structure
Structure	3D Structure		2D Structure
Formula	CH3O5P
InChI	InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)
InChIKey	ZJAOAACCNHFJAH-UHFFFAOYSA-N
Canonical SMILES	C(=O)(O)P(=O)(O)O
External Link
External Link	Pubchem ID	3415

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects BM027 Decreased renal excretion due to nephrotoxicity BM044 Additive myelosuppressive effects BM049 Increased risk of atrioventricular block BM063 Increased risk of hypocalcemia BM065 Increased risk of hypokalemia BM066 Increased risk of hypomagnesemia BM069 Increased risk of lowers seizure threshold BM072 Increased risk of nephrotoxicity BM076 Increased risk of prolong QT interval BM081 Increased risk of ventricular arrhythmias
Relation Graph

Full list of drugs interacting with Foscarnet
Affected excretion pathways
	Decreased renal excretion due to nephrotoxicity					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0576		Entecavir	C12H15N5O3	135398508	Moderate		Inter Info	[181]
D0668		Flucytosine	C4H4FN3O	3366	Moderate		Inter Info	[243]
D1241		Pemetrexed	C20H21N5O6	135410875	Moderate		Inter Info	[274]
D1389		Remdesivir	C27H35N6O8P	121304016	Moderate		Inter Info	[5], [7], [284], [285], [286]
D1543		Telbivudine	C10H14N2O5	159269	Moderate		Inter Info	[289]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[307]
Pharmacodynamic additive effects
	Additive myelosuppressive effects					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0370		Clozapine	C18H19ClN4	135398737	Major		Inter Info	[30], [31]
	Increased risk of atrioventricular block					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[7], [105], [304]
	Increased risk of hypocalcemia					Drug Num: 34
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0056		Amikacin	C22H43N5O13	37768	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D0057		Amikacin (liposome)	C22H43N5O13	37768	Major		Inter Info	[22], [3], [18]
D0075		Amphotericin B	C47H73NO17	5280965	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [9], [10], [11], [12], [13], [14], [17], [19], [20], [21]
D0076		Amphotericin B (cholesteryl sulfate)	C47H73NO17	5280965	Major		Inter Info	[22], [11], [12]
D0077		Amphotericin B (lipid complex)	C47H73NO17	5280965	Major		Inter Info	[22], [11], [12]
D0078		Amphotericin B (liposomal)	C47H73NO17	5280965	Major		Inter Info	[22], [11], [12]
D0615		Etelcalcetide	C38H73N21O10S2	71511839	Major		Inter Info	[7]
D0718		Gentamicin	C21H43N5O7	3467	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D0876		Kanamycin	C18H36N4O11	6032	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D1120		Neomycin	C23H46N6O13	8378	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D1126		Netilmicin	C21H41N5O7	441306	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D1246		Pentamidine	C19H24N4O2	4735	Major		Inter Info	[132], [17], [133]
D1304		Plazomicin	C25H48N6O10	42613186	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D1507		Streptomycin	C21H39N7O12	19649	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D1597		Tobramycin	C18H37N5O9	36294	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]
D0344		Cisplatin	Cl2H6N2Pt	5702198	Moderate		Inter Info	[132], [17], [133]
D0034		Alendronic acid	C4H13NO7P2	2088	Moderate		Inter Info	[132], [17], [133]
D0055		Amifostine	C5H15N2O3PS	2141	Moderate		Inter Info	[132], [17], [133]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[132], [17], [133]
D0443		Denosumab	NA	NA	Moderate		Inter Info	[132], [17], [133]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[132], [17], [133]
D0709		Gallium nitrate	GaN3O9	61635	Moderate		Inter Info	[132], [17], [133]
D0903		Lenvatinib	C21H19ClN4O4	9823820	Moderate		Inter Info	[132], [17], [133]
D1086		Monopotassium phosphate	H2KO4P	516951	Moderate		Inter Info	[132], [17], [133]
D1199		Oxidronic acid	CH6O7P2	27304	Moderate		Inter Info	[132], [17], [133]
D1305		Plicamycin	C52H76O24	163659	Moderate		Inter Info	[132], [17], [133]
D1412		Risedronic acid	C7H11NO7P2	5245	Moderate		Inter Info	[132], [17], [133]
D1426		Romosozumab	NA	NA	Moderate		Inter Info	[132], [17], [133]
D1443		Samarium (153Sm) lexidronam	Sm	23951	Moderate		Inter Info	[132], [17], [133]
D1481		Sodium cellulose phosphate	NA	NA	Moderate		Inter Info	[132], [17], [133]
D1486		Sodium phosphate, monobasic	NA	NA	Moderate		Inter Info	[132], [17], [133]
D1584		Tiludronic acid	C7H9ClO6P2S	60937	Moderate		Inter Info	[132], [17], [133]
D1441		Salmon calcitonin	C145H240N44O48S2	16129616	Moderate		Inter Info	[132], [17], [133]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[132], [17], [133]
	Increased risk of hypokalemia					Drug Num: 12
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0148		Beclomethasone dipropionate	C28H37ClO7	21700	Moderate		Inter Info	[178], [179], [180]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[178], [179], [180]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[178], [179], [180]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[178], [179], [180]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[178], [179], [180]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[178], [179], [180]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[178], [179], [180]
D0926		Licorice	C42H62O16Zn	163463	Moderate		Inter Info	[269], [270], [271]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[178], [179], [180]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[178], [179], [180]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[178], [179], [180]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[178], [179], [180]
	Increased risk of hypomagnesemia					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0458		Dexlansoprazole	C16H14F3N3O2S	9578005	Moderate		Inter Info	[238]
D1373		Rabeprazole	C18H21N3O3S	5029	Moderate		Inter Info	[238]
D0892		Lansoprazole	C16H14F3N3O2S	3883	Moderate		Inter Info	[238]
D1179		Omeprazole	C17H19N3O3S	4594	Moderate		Inter Info	[238]
D1222		Pantoprazole	C16H15F2N3O4S	4679	Moderate		Inter Info	[238]
	Increased risk of lowers seizure threshold					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0220		Bupropion	C13H18ClNO	444	Major		Inter Info	[56], [57], [23], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69]
D1616		Tramadol	C16H25NO2	33741	Major		Inter Info	[165], [68], [67], [166]
D0054		Amifampridine	C5H7N3	5918	Moderate		Inter Info	[7], [117], [189]
D0722		Ginkgo biloba	NA	NA	Moderate		Inter Info	[248], [249], [250], [251], [252], [253], [254], [255]
D0932		Lindane	C6H6Cl6	727	Moderate		Inter Info	[301], [302], [303]
	Increased risk of nephrotoxicity					Drug Num: 31
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0335		Cidofovir	C8H14N3O6P	60613	Major		Inter Info	[25]
D0402		Cyclosporine	C62H111N11O12	5284373	Major		Inter Info	[32], [17]
D0472		Diatrizoate	C11H9I3N2O4	2140	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D0432		Deferasirox	C21H15N3O4	214348	Major		Inter Info	[92], [93]
D0629		Everolimus	C53H83NO14	6442177	Major		Inter Info	[97], [98], [99]
D0761		Human botulinum neurotoxin A/B immune globulin	NA	NA	Major		Inter Info	[107], [108], [109]
D0763		Human cytomegalovirus immune globulin	NA	NA	Major		Inter Info	[107], [108], [109]
D0768		Human Rho(D) immune globulin	NA	NA	Major		Inter Info	[107], [108], [109]
D0805		Inotersen	C230H318N69O121P19S19	121492004	Major		Inter Info	[7], [111]
D0831		Iodipamide	C20H14I6N2O6	3739	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D0832		Iodixanol	C35H44I6N6O15	3724	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D0833		Iohexol	C19H26I3N3O9	3730	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D0834		Iopamidol	C17H22I3N3O8	65492	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D0836		Iopromide	C18H24I3N3O8	3736	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D0837		Iothalamic acid	C11H9I3N2O4	3737	Major		Inter Info	[35], [36], [37]
D0838		Ioversol	C18H24I3N3O9	3741	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D0839		Ioxilan	C18H24I3N3O8	3743	Major		Inter Info	[33], [34], [35], [36], [37], [38], [39]
D1476		Sirolimus	C51H79NO13	5284616	Major		Inter Info	[97], [98], [99]
D1526		Tacrolimus	C44H69NO12	445643	Major		Inter Info	[97], [98], [99]
D1549		Temsirolimus	C56H87NO16	6918289	Major		Inter Info	[97], [98], [99]
D0765		Human immunoglobulin G (intravenous)	NA	NA	Major		Inter Info	[107], [108], [109]
D0145		Balsalazide	C17H15N3O6	54585	Moderate		Inter Info	[227], [228], [229], [230]
D0357		Clofarabine	C10H11ClFN5O3	119182	Moderate		Inter Info	[235]
D0783		Ibandronate	C9H23NO7P2	60852	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267]
D1030		Methoxyflurane	C3H4Cl2F2O	4116	Moderate		Inter Info	[7]
D1173		Olsalazine	C14H10N2O6	22419	Moderate		Inter Info	[227], [228], [229], [230]
D1517		Sulfasalazine	C18H14N4O5S	5339	Moderate		Inter Info	[227], [228], [229], [230]
D1672		Valaciclovir	C13H20N6O4	135398742	Moderate		Inter Info	[7], [300]
D1009		Mesalazine	C7H7NO3	4075	Moderate		Inter Info	[228], [229], [230]
D1217		Pamidronic acid	C3H11NO7P2	4674	Moderate		Inter Info	[308], [259], [266]
D1727		Zoledronic acid	C5H10N2O7P2	68740	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [262], [263], [264], [265], [266], [267]
	Increased risk of prolong QT interval					Drug Num: 150
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0084		Anagrelide	C10H7Cl2N3O	135409400	Major		Inter Info	[23], [5], [7], [24]
D0345		Citalopram	C20H21FN2O	2771	Major		Inter Info	[23], [5], [7], [26], [27], [28], [29]
D0508		Disopyramide	C21H29N3O	3114	Major		Inter Info	[23], [5], [7], [40], [41], [42], [43], [44], [45], [46], [47], [48], [28]
D0513		Dofetilide	C19H27N3O5S2	71329	Major		Inter Info	[23], [5], [7], [49]
D0535		Droperidol	C22H22FN3O2	3168	Major		Inter Info	[23], [5], [7], [50], [51], [28]
D0066		Amiodarone	C25H29I2NO3	2157	Major		Inter Info	[23], [5], [7], [40], [41], [42], [43], [44], [45], [46], [47], [48], [28]
D0067		Amisulpride	C17H27N3O4S	2159	Major		Inter Info	[52]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Major		Inter Info	[55]
D0170		Bepridil	C24H34N2O	2351	Major		Inter Info	[23], [5], [7], [40], [41], [42], [43], [44], [45], [46], [47], [48], [28]
D0230		Cabozantinib	C28H24FN3O5	25102847	Major		Inter Info	[7], [70]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Major		Inter Info	[23], [5], [7], [71]
D0320		Chloroquine	C18H26ClN3	2719	Major		Inter Info	[72], [7], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Major		Inter Info	[91]
D0514		Dolasetron	C19H20N2O3	3033818	Major		Inter Info	[23], [5], [7], [94]
D0534		Dronedarone	C31H44N2O5S	208898	Major		Inter Info	[23], [5], [7], [95]
D0554		Efavirenz	C14H9ClF3NO2	64139	Major		Inter Info	[96]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Major		Inter Info	[101], [23], [5], [7], [102], [103], [104], [105], [106]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Major		Inter Info	[72], [7], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90]
D0791		Iloperidone	C24H27FN2O4	71360	Major		Inter Info	[23], [5], [7], [110], [28]
D0872		Ivosidenib	C28H22ClF3N6O3	71657455	Major		Inter Info	[114]
D0899		Lefamulin	C28H45NO5S	25185057	Major		Inter Info	[115]
D0909		Levacetylmethadol	C23H31NO2	15130	Major		Inter Info	[7], [116], [28]
D0960		Lumefantrine	C30H32Cl3NO	6437380	Major		Inter Info	[5], [7], [117]
D0965		Macimorelin	C26H30N6O3	9804938	Major		Inter Info	[118]
D1010		Mesoridazine	C21H26N2OS2	4078	Major		Inter Info	[23], [5], [7], [119], [28]
D1063		Mifepristone	C29H35NO2	55245	Major		Inter Info	[23], [5], [7], [120]
D1136		Nilotinib	C28H22F3N7O	644241	Major		Inter Info	[23], [5], [7], [31]
D1190		Osimertinib	C28H33N7O2	71496458	Major		Inter Info	[121]
D1223		Papaverine	C20H21NO4	4680	Major		Inter Info	[123], [124], [125], [126], [127], [128], [129], [130]
D1230		Pasireotide	C58H66N10O9	9941444	Major		Inter Info	[23], [5], [7], [131]
D1292		Pimozide	C28H29F2N3O	16362	Major		Inter Info	[7], [50], [134], [28]
D1343		Procainamide	C13H21N3O	4913	Major		Inter Info	[23], [5], [7], [40], [41], [42], [43], [44], [45], [46], [47], [48], [28]
D1371		Quinidine	C20H24N2O2	441074	Major		Inter Info	[23], [5], [7], [40], [41], [42], [43], [44], [45], [46], [47], [48], [28]
D1444		Saquinavir	C38H50N6O5	441243	Major		Inter Info	[135], [136], [23], [5], [7], [137], [138]
D1459		Selpercatinib	C29H31N7O3	134436906	Major		Inter Info	[7], [139]
D1574		Thioridazine	C21H26N2S2	5452	Major		Inter Info	[23], [5], [7], [141], [50], [142], [143], [144], [28]
D1612		Toremifene	C26H28ClNO	3005573	Major		Inter Info	[23], [5], [7], [145]
D1681		Vandetanib	C22H24BrFN4O2	3081361	Major		Inter Info	[23], [5], [7], [146]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Major		Inter Info	[23], [5], [7], [147]
D0750		Haloperidol	C21H23ClFNO2	3559	Major		Inter Info	[23], [5], [7], [148], [149], [150], [151], [152], [153], [28]
D0787		Ibutilide	C20H36N2O3S	60753	Major		Inter Info	[23], [5], [7], [154]
D1017		Methadone	C21H27NO	4095	Major		Inter Info	[23], [5], [7], [155], [156], [157], [158], [159], [160], [161], [162], [163], [164], [28]
D1498		Sotalol	C12H20N2O3S	5253	Major		Inter Info	[23], [5], [7], [40], [41], [42], [43], [44], [45], [46], [47], [48], [28]
D1726		Ziprasidone	C21H21ClN4OS	60854	Major		Inter Info	[23], [5], [7], [50], [167], [28]
D0003		Abarelix	C72H95ClN14O14	16131215	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[23], [5], [7], [175], [28]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0139		Azithromycin	C38H72N2O12	447043	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0597		Erythromycin	C37H67NO13	12560	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0667		Fluconazole	C13H12F2N6O	3365	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0676		Fluoxetine	C17H18F3NO	3386	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0682		Flutamide	C11H11F3N2O3	3397	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0007		Abiraterone	C24H31NO	132971	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[176], [177], [28]
D0072		Amoxapine	C17H16ClN3O	2170	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0095		Apalutamide	C21H15F4N5O2S	24872560	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[5], [7], [220], [221], [222], [223], [224], [225]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[23], [5], [7], [226], [28]
D0115		Astemizole	C28H31FN4O	2247	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[7], [234]
D0336		Cilostazol	C20H27N5O2	2754	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0349		Clarithromycin	C38H69NO13	84029	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0358		Clofazimine	C27H22Cl2N4	2794	Moderate		Inter Info	[236]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[237]
D0429		Daunorubicin	C27H29NO10	30323	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Moderate		Inter Info	[176], [177], [28]
D0437		Degarelix	C82H103ClN18O16	16136245	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0467		Dextropropoxyphene	C22H29NO2	10100	Moderate		Inter Info	[176], [177], [28]
D0525		Doxepin	C19H21NO	667477	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[176], [177], [28]
D0569		Encorafenib	C22H27ClFN7O4S	50922675	Moderate		Inter Info	[239]
D0577		Entrectinib	C31H34F2N6O2	25141092	Moderate		Inter Info	[5], [7], [240]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[23], [5], [7], [241]
D0632		Ezogabine	C16H18FN3O2	121892	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0636		Famotidine	C8H15N7O2S3	5702160	Moderate		Inter Info	[5], [7], [242]
D0664		Flecainide	C17H20F6N2O3	3356	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[247]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0751		Halothane	C2HBrClF3	3562	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0758		Histrelin	C66H86N18O12	25077993	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0781		Hydroxyzine	C21H27ClN2O2	3658	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0788		Idarubicin	C26H27NO9	42890	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0806		Inotuzumab ozogamicin	NA	NA	Moderate		Inter Info	[7], [268]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[7]
D0940		Lithium carbonate	CLi2O3	11125	Moderate		Inter Info	[176], [177], [28]
D0948		Lopinavir	C37H48N4O5	92727	Moderate		Inter Info	[23], [5], [272]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1137		Nilutamide	C12H10F3N3O4	4493	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D1158		Nortriptyline	C19H21N	4543	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1181		Ondansetron	C18H19N3O	4595	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1189		Osilodrostat	C13H10FN3	44139752	Moderate		Inter Info	[7], [273]
D1215		Paliperidone	C23H27FN4O3	115237	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1254		Perflutren	C3F8	6432	Moderate		Inter Info	[275], [276]
D1290		Pimavanserin	C25H34FN3O2	10071196	Moderate		Inter Info	[279]
D1302		Pitolisant	C17H26ClNO	9948102	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1315		Posaconazole	C37H42F2N8O4	468595	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1339		Primaquine	C15H21N3O	4908	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1342		Probucol	C31H48O2S2	4912	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1353		Propafenone	C21H27NO3	4932	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[23], [5], [7], [50], [280], [281], [282], [283], [28]
D1388		Relugolix	C29H27F2N7O5S	10348973	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1463		Sevoflurane	C4H3F7O	5206	Moderate		Inter Info	[23], [5], [7], [287]
D1491		Solifenacin	C23H26N2O2	154059	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[23], [5], [7], [288]
D1533		Tamoxifen	C26H29NO	2733526	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1542		Telavancin	C80H106Cl2N11O27P	3081362	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[23], [5], [7], [290], [291], [292]
D1560		Tetrabenazine	C19H27NO3	6018	Moderate		Inter Info	[23], [5], [7], [293], [28]
D1596		Tizanidine	C9H8ClN5S	5487	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1624		Trazodone	C19H22ClN5O	5533	Moderate		Inter Info	[295], [296], [220], [297], [298], [299], [28]
D1634		Triclabendazole	C14H9Cl3N2OS	50248	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1647		Trimipramine	C20H26N2	5584	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1651		Triptorelin	C64H82N18O13	25074470	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0737		Goserelin	C59H84N18O14	5311128	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D0908		Leuprolide	C59H84N16O12	657181	Moderate		Inter Info	[7], [168], [169], [170], [171], [172], [173], [174]
D1075		Mirtazapine	C17H19N3	4205	Moderate		Inter Info	[305]
D1166		Olanzapine	C17H20N4S	135398745	Moderate		Inter Info	[5], [7], [306]
D1210		Oxytocin	C43H66N12O12S2	439302	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1216		Palonosetron	C19H24N2O	6337614	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1361		Protriptyline	C19H21N	4976	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1383		Ranolazine	C24H33N3O4	56959	Moderate		Inter Info	[309], [310]
D1497		Sorafenib	C21H16ClF3N4O3	216239	Moderate		Inter Info	[23], [5], [7], [311]
D1555		Terfenadine	C32H41NO2	5405	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1638		Triflupromazine	C18H19F3N2S	5568	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1683		Vasopressin	C46H65N15O12S2	644077	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[23], [5], [7], [50], [176], [177], [28]
D1051		Metronidazole	C6H9N3O3	4173	Minor		Inter Info	[5], [312], [313], [314]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Minor		Inter Info	[23], [5], [7], [315], [316], [317], [318]
	Increased risk of ventricular arrhythmias					Drug Num: 37
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0107		Arsenic trioxide	As2O3	14888	Major		Inter Info	[53], [54]
D0661		Fingolimod	C19H33NO2	107970	Major		Inter Info	[23], [5], [7], [100], [29]
D0868		Ivabradine	C27H36N2O5	132999	Major		Inter Info	[7], [112], [113]
D1211		Ozanimod	C23H24N4O3	52938427	Major		Inter Info	[122]
D1474		Siponimod	C29H35F3N2O3	44599207	Major		Inter Info	[5], [140]
D0025		Adenosine	C10H13N5O4	60961	Moderate		Inter Info	[23], [182], [5], [7], [183], [184], [185], [186], [187], [188]
D0103		Arformoterol	C19H24N2O4	3083544	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D0184		Bisacodyl	C22H19NO4	2391	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D0269		Castor oil	C57H104O9	14030006	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D0691		Formoterol	C19H24N2O4	3410	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D0701		Frangula purshiana bark	NA	NA	Moderate		Inter Info	[5], [7], [233]
D0707		Galantamine	C17H21NO3	9651	Moderate		Inter Info	[23], [5], [7], [244], [245], [246]
D0731		Glycerin	C3H8O3	753	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D0797		Indacaterol	C24H28N2O3	6918554	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D0859		Isoprenaline	C11H17NO3	3779	Moderate		Inter Info	[203], [213], [216]
D0887		Lactitol	C12H24O11	157355	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D0888		Lactulose	C12H22O11	11333	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D0924		Levosalbutamol	C13H21NO3	123600	Moderate		Inter Info	[203], [213], [216]
D0970		Magnesium citrate	C12H10Mg3O14	6099959	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D0973		Magnesium hydroxide	H2MgO2	14791	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D1069		Mineral oil	NA	NA	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D1171		Olodaterol	C21H26N2O5	11504295	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D1185		Orciprenaline	C11H17NO3	4086	Moderate		Inter Info	[203], [213], [216]
D1266		Phenolphthalein	C20H14O4	4764	Moderate		Inter Info	[23], [5], [7], [231], [232], [233]
D1287		Picosulfuric acid	C18H15NO8S2	5243	Moderate		Inter Info	[23], [277], [278]
D1298		Pirbuterol	C12H20N2O3	4845	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D1308		Polyethylene glycol (3350 with electrolytes)	C2H6O2	174	Moderate		Inter Info	[23], [277], [278]
D1309		Polyethylene glycol (3350)	C2H6O2	174	Moderate		Inter Info	[5], [7], [233]
D1414		Ritodrine	C17H21NO3	33572	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[203], [213], [216]
D1440		Salmeterol	C25H37NO4	5152	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D1488		Sodium sulfate	Na2O4S	24436	Moderate		Inter Info	[23], [277], [278]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[5], [7], [294]
D1695		Vilanterol	C24H33Cl2NO5	10184665	Moderate		Inter Info	[203], [213], [216]
D0854		Isoetharine	C13H21NO3	3762	Moderate		Inter Info	[190], [191], [192], [193], [194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219]
D1525		Tacrine	C13H14N2	1935	Moderate		Inter Info	[23], [5], [7], [244], [245], [246]

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