Details of Drug

Drug General Information (ID: D0419)
Drug Name	Dapsone
Drug Type	Small molecule
Drug Synonymous	Aczone; Atrisone; Avlosulfon; Avlosulfone; Avlosulphone; Avsulfor; Croysulfone; Croysulphone; DADPS; DDS; Dapson; Dapsona; Dapsonum; Diaminodifenilsulfona; Diaminodiphenylsulfone; Diaphenylsulfon; Diaphenylsulfone; Diaphenylsulphon; Diaphenylsulphone; Diphenasone; Diphone; Disulone; Dubronax; Dubronaz; Dumitone; Eporal; Novophone; Protogen; Sulfadione; Sulfona; Sulfonyldianiline; Sulphadione; Sulphonyldianiline; Tarimyl; Udolac; Araldite HT; D SS; Diaminodifenilsulfona [Spanish]; Diaminodiphenyl sulfone;Fatol Brand of Dapsone; Metabolite C; Orsade Brand of Dapsone; Sulfone ucb; Sumicure S; Araldite HT 976; F 1358; HT 976; HY 976; Hardener HT 976; W R 448; WR 448; ALBB-005917; AZT + Dapsone cominbation; Aczone (TN); DDS (pharmaceutical); DDS, diaphenylsulfone; DDS, pharmaceutical; DSS (VAN); Dapsoderm-X; Dapson-Fatol; Dapsona [INN-Spanish]; Dapsone (USP); Dapsone [USAN:BAN]; Dapsonum [INN-Latin];Diamino-diphenyl sulphone; Diaphenylsulfone (JAN); IN-201; Mex-America Brand of Dapsone; P-Aminophenyl sulfone; Sulfanona-mae; Sulfon-mere; Sulfona-MAE; Sulphon-mere; Bis(4-aminophenyl) sulfone; Bis(4-aminophenyl)sulfone; Bis(4-aminophenyl)sulphone; Bis(p-aminophenyl) sulfone; Bis(p-aminophenyl)sulphone; Di(4-aminophenyl) sulfone; Di(4-aminophenyl)sulfone; Di(4-aminophenyl)sulphone; Di(p-aminophenyl) sulfone; Di(p-aminophenyl)sulphone; P,p-Diaminodiphenyl sulphone; P,p-Sulfonylbisbenzamine; P,p-Sulfonylbisbenzenamine; P,p-Sulphonylbisbenzamine; P,p-Sulphonylbisbenzenamine; P,p-Sulphonyldianiline; N, N'-Diphenyl sulfondiamide; N,N'-Diphenyl sulfondiamide; P, p'-Sulfonyldianiline; P,p'-Diaminodiphenyl sulfone; P,p'-sulfonyldianiline; Diamino-4,4'-diphenyl sulfone; Diamino-4,4'-diphenyl sulphone; Sulfone, 4,4'-Diaminophenyl; (4-sulfanilylphenyl)amine; 1,1'-Sulfonylbis(4-aminobenzene); 1,1'-Sulfonylbis[4-aminobenzene]; 1,1'-Sulphonylbis(4-aminobenzene); 4,4' Diaminophenyl Sulfone; 4,4'-Dapsone; 4,4'-Diaminodiphenyl sulfone; 4,4'-Diaminodiphenyl suphone; 4,4'-Diaminodiphenylsulfone; 4,4'-Sulfonylbisaniline; 4,4'-Sulfonylbisbenzamine; 4,4'-Sulfonylbisbenzenamine; 4,4'-Sulfonyldianiline;4,4'-Sulfonyldianiline (Dapsone); 4,4'-Sulphonylbisbenzamine; 4,4'-Sulphonylbisbenzenamine; 4,4'-Sulphonyldianiline; 4,4'-diaminophenyl sulfone; 4,4-Diaminodifenylsulfon; 4,4-Diaminodifenylsulfon [Czech]; 4,4-Sulfonyldianiline; 4-(4-aminophenyl)sulfonylaniline; 4-Aminop henyl sulfone; 4-Aminophenyl sulfone; 4-Aminophenylsulfone; 4-[(4-aminobenzene)sulfonyl]aniline; 4-[(4-aminophenyl)sulfonyl]aniline Click to Show/Hide
Disease Class	CA40: Pneumonia
Therapeutic Class	Antiinflammatory Agents
Structure
Structure	3D Structure		2D Structure
Formula	C12H12N2O2S
InChI	1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChIKey	MQJKPEGWNLWLTK-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
External Link
	Pubchem ID	2955
	CAS Number	80-08-0
	CHEBI ID	4325
	TTD ID	D0MA9N
	INTEDE ID	DR0415

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM003 Affected organization distribution AM004 Affected intra/extra-hepatic metabolism AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM004 Adsorption BM014 Interference of cell/tissue uptake BM017 CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM024 Competitive inhibition of metabolic enzyme BM028 Competitive inhibition of renal tubular secretion BM043 Additive immunosuppressive effects BM044 Additive myelosuppressive effects BM071 Increased risk of methemoglobinemia BM074 Increased risk of peripheral neuropathy BM075 Increased risk of photosensitivity reactions BM100 Antagonize the effect of vaccine/toxoid BM107 Attenuated pharmacological effects (Unspecific)
Relation Graph

Full list of drugs interacting with Dapsone
Affected gastrointestinal absorption
	Adsorption					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0021		Activated charcoal	C	5462310	Moderate		Inter Info	[32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56]
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1817		Indium In-111 oxyquinoline	C27H18InN3O3	16685037	Moderate		Inter Info	[85]
D1822		Iodide I-123	I-	135300	Moderate		Inter Info	[86], [87], [88]
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 26
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1444		Saquinavir	C38H50N6O5	441243	Major		Inter Info	[7], [1], [19]
D0002		Abametapir (topical)	C12H12N2	15664	Moderate		Inter Info	[30]
D0100		Aprepitant	C23H21F7N4O3	135413536	Moderate		Inter Info	[60], [61]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[7], [1], [66]
D0413		Dalfopristin	C34H50N4O9S	6323289	Moderate		Inter Info	[68]
D0497		Diltiazem	C22H26N2O4S	39186	Moderate		Inter Info	[69], [70], [71], [72], [73]
D0642		Fenofibrate	C20H21ClO4	3339	Moderate		Inter Info	[7], [1], [79]
D0693		Fosaprepitant	C23H22F7N4O6P	135413538	Moderate		Inter Info	[60], [61]
D0699		Fostamatinib	C23H26FN6O9P	11671467	Moderate		Inter Info	[80]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[83]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[84]
D0867		Itraconazole	C35H38Cl2N8O4	55283	Moderate		Inter Info	[89], [7], [90], [91], [92], [93], [94], [95], [96]
D0869		Ivacaftor	C24H28N2O3	16220172	Moderate		Inter Info	[97], [98], [99], [100]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[101]
D0899		Lefamulin	C28H45NO5S	25185057	Moderate		Inter Info	[102], [103], [87]
D1063		Mifepristone	C29H35NO2	55245	Moderate		Inter Info	[109]
D1112		Nateglinide	C19H27NO3	5311309	Moderate		Inter Info	[110]
D1117		Nefazodone	C25H32ClN5O2	4449	Moderate		Inter Info	[111]
D1136		Nilotinib	C28H22F3N7O	644241	Moderate		Inter Info	[112]
D1143		Nitisinone	C14H10F3NO5	115355	Moderate		Inter Info	[18], [7], [113]
D1398		Ribociclib	C23H30N8O	44631912	Moderate		Inter Info	[123], [124], [125], [126], [127], [128], [129], [130], [131]
D1415		Ritonavir	C37H48N6O5S2	392622	Moderate		Inter Info	[138], [139], [140]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[66]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[7], [1], [149]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[152], [153]
D1119		Nelfinavir	C32H45N3O4S	64143	Moderate		Inter Info	[154]
	CYP450 enzyme induction					Drug Num: 21
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0044		Alpelisib	C19H22F3N5O2S	56649450	Moderate		Inter Info	[57]
D0095		Apalutamide	C21H15F4N5O2S	24872560	Moderate		Inter Info	[1], [59]
D0194		Bosentan	C27H29N5O6S	104865	Moderate		Inter Info	[63]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[1], [67]
D0545		Echinacea	NA	NA	Moderate		Inter Info	[7], [74]
D0554		Efavirenz	C14H9ClF3NO2	64139	Moderate		Inter Info	[75]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[76], [7], [1], [77]
D0628		Etravirine	C20H15BrN6O	193962	Moderate		Inter Info	[78]
D0906		Letermovir	C29H28F4N4O4	45138674	Moderate		Inter Info	[104]
D0953		Lorlatinib	C21H19FN6O2	71731823	Moderate		Inter Info	[105]
D1399		Rifabutin	C46H62N4O11	135398743	Moderate		Inter Info	[18], [7], [1], [132]
D1400		Rifampicin	C43H58N4O12	135398735	Moderate		Inter Info	[133], [134], [135]
D1401		Rifapentine	C47H64N4O12	135403821	Moderate		Inter Info	[136], [137]
D1433		Rufinamide	C10H8F2N4O	129228	Moderate		Inter Info	[1], [141]
D1493		Somapacitan	C54H95N13O20S2	129894493	Moderate		Inter Info	[7], [1], [143]
D1495		Somatrem	C43H72N14O14	5487805	Moderate		Inter Info	[7], [1], [144], [143]
D1546		Telotristat ethyl	C27H26ClF3N6O3	25181577	Moderate		Inter Info	[1], [145]
D1494		Somatotropin	NA	NA	Moderate		Inter Info	[7], [1], [143]
D1652		Troglitazone	C24H27NO5S	5591	Moderate		Inter Info	[155], [156], [157], [158], [159], [160], [161]
D0106		Armodafinil	C15H15NO2S	9690109	Minor		Inter Info	[162], [163], [164], [165], [166]
D1081		Modafinil	C15H15NO2S	4236	Minor		Inter Info	[162], [163], [164], [165], [166]
	Competitive inhibition of metabolic enzyme					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1476		Sirolimus	C51H79NO13	5284616	Moderate		Inter Info	[142], [140]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[142], [140]
D1549		Temsirolimus	C56H87NO16	6918289	Moderate		Inter Info	[142], [140]
Affected excretion pathways
	Competitive inhibition of renal tubular secretion					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1341		Probenecid	C13H19NO4S	4911	Moderate		Inter Info	[121]
Pharmacodynamic additive effects
	Additive immunosuppressive effects					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1162		Ocrelizumab	NA	NA	Moderate		Inter Info	[114]
D1375		Radium Ra 223 dichloride	NA	NA	Moderate		Inter Info	[122]
D1671		Ustekinumab	NA	NA	Moderate		Inter Info	[147]
D1720		Zidovudine	C10H13N5O4	35370	Moderate		Inter Info	[7], [1], [151]
	Additive myelosuppressive effects					Drug Num: 7
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0348		Cladribine	C10H12ClN5O3	20279	Major		Inter Info	[1], [2]
D0370		Clozapine	C18H19ClN4	135398737	Major		Inter Info	[1], [5], [6]
D0433		Deferiprone	C7H9NO2	2972	Major		Inter Info	[7], [8], [9]
D0033		Alemtuzumab	NA	NA	Moderate		Inter Info	[26]
D0710		Ganciclovir	C9H13N5O4	135398740	Moderate		Inter Info	[7], [1], [81], [82]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Moderate		Inter Info	[115]
D1676		Valganciclovir	C14H22N6O5	135413535	Moderate		Inter Info	[7], [1], [81], [82]
	Increased risk of methemoglobinemia					Drug Num: 26
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1148		Nitrous acid	HNO2	24529	Major		Inter Info	[10], [11], [12]
D1337		Prilocaine	C13H20N2O	4906	Major		Inter Info	[13], [7], [1], [14], [15], [16], [17]
D1338		Prilocaine (topical)	C13H20N2O	4906	Major		Inter Info	[18], [7], [17]
D0011		Acetaminophen	C8H9NO2	1983	Moderate		Inter Info	[7], [31]
D0083		Amyl Nitrite	C5H11NO2	10026	Moderate		Inter Info	[7], [31]
D0163		Benzocaine (topical)	C9H11NO2	2337	Moderate		Inter Info	[1], [14], [62]
D0339		Cinchocaine (topical)	C20H29N3O2	3025	Moderate		Inter Info	[1], [14], [62]
D0377		Cocaine (nasal)	C17H21NO4	446220	Moderate		Inter Info	[1], [14], [62]
D0378		Cocaine (topical)	C17H21NO4	446220	Moderate		Inter Info	[1], [14], [62]
D0861		Isosorbide dinitrate	C6H8N2O8	6883	Moderate		Inter Info	[7], [31]
D0862		Isosorbide mononitrate	C6H9NO6	27661	Moderate		Inter Info	[7], [31]
D1835		Lidocaine (ophthalmic)	C14H22N2O	3676	Moderate		Inter Info	[1], [14], [62]
D0928		Lidocaine (topical)	C14H22N2O	3676	Moderate		Inter Info	[1], [14], [62]
D1146		Nitroglycerin	C3H5N3O9	4510	Moderate		Inter Info	[7], [31]
D1147		Nitroprusside	C5FeN6O	11953891	Moderate		Inter Info	[7], [31]
D1852		Oxybuprocaine (ophthalmic)	C17H28N2O3	4633	Moderate		Inter Info	[1], [14], [62]
D1339		Primaquine	C15H21N3O	4908	Moderate		Inter Info	[7], [31]
D1870		Proparacaine (ophthalmic)	C16H26N2O3	4935	Moderate		Inter Info	[1], [14], [62]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[7], [31]
D1513		Sulfadiazine	C10H10N4O2S	5215	Moderate		Inter Info	[7], [31]
D1514		Sulfadoxine	C12H14N4O4S	17134	Moderate		Inter Info	[7], [31]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Moderate		Inter Info	[7], [31]
D1519		Sulfisoxazole	C11H13N3O3S	5344	Moderate		Inter Info	[7], [31]
D1530		Tafenoquine	C24H28F3N3O3	115358	Moderate		Inter Info	[7], [31]
D1904		Tetracaine (ophthalmic)	C15H24N2O2	5411	Moderate		Inter Info	[1], [14], [62]
D1562		Tetracaine (topical)	C15H24N2O2	5411	Moderate		Inter Info	[1], [14], [62]
	Increased risk of peripheral neuropathy					Drug Num: 79
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0023		Adalimumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0193		Bortezomib	C19H25BN4O4	387447	Moderate		Inter Info	[27], [28], [29]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[23], [24], [25]
D0120		Atorvastatin	C33H35FN2O5	60823	Moderate		Inter Info	[23], [24], [25]
D0126		Auranofin	C20H34AuO9PS	24199313	Moderate		Inter Info	[23], [24], [25]
D0127		Aurothioglucose	C6H11AuO5S	454937	Moderate		Inter Info	[23], [24], [25]
D0162		Benznidazole	C12H12N4O3	31593	Moderate		Inter Info	[23], [24], [25]
D0199		Brentuximab vedotin	NA	NA	Moderate		Inter Info	[23], [64], [65]
D0227		Cabazitaxel	C45H57NO14	9854073	Moderate		Inter Info	[23], [24], [25]
D0260		Carboplatin	C6H12N2O4Pt	426756	Moderate		Inter Info	[23], [24], [25]
D0261		Carfilzomib	C40H57N5O7	11556711	Moderate		Inter Info	[23], [24], [25]
D0304		Certolizumab pegol	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[23], [24], [25]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[23], [24], [25]
D0344		Cisplatin	Cl2H6N2Pt	5702198	Moderate		Inter Info	[23], [24], [25]
D0380		Colchicine	C22H25NO6	6167	Moderate		Inter Info	[23], [24], [25]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Moderate		Inter Info	[23], [24], [25]
D0496		Diiodohydroxyquinoline	C9H5I2NO	3728	Moderate		Inter Info	[23], [24], [25]
D0501		Dinutuximab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0509		Disulfiram	C10H20N2S4	3117	Moderate		Inter Info	[23], [24], [25]
D0511		Docetaxel	C43H53NO14	148124	Moderate		Inter Info	[23], [24], [25]
D0560		Elotuzumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0571		Enfortumab vedotin	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[23], [24], [25]
D0616		Ethambutol	C10H24N2O2	14052	Moderate		Inter Info	[23], [24], [25]
D1731		Ethionamide	C8H10N2S	2761171	Moderate		Inter Info	[23], [24], [25]
D0627		Etoposide	C29H32O13	36462	Moderate		Inter Info	[23], [24], [25]
D0669		Fludarabine	C10H12FN5O4	657237	Moderate		Inter Info	[23], [24], [25]
D0686		Fluvastatin	C24H26FNO4	446155	Moderate		Inter Info	[23], [24], [25]
D0736		Golimumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0770		Hydralazine	C8H8N4	3637	Moderate		Inter Info	[23], [24], [25]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[23], [24], [25]
D0841		Ipilimumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[23], [24], [25]
D0873		Ixabepilone	C27H42N2O5S	6445540	Moderate		Inter Info	[23], [24], [25]
D0874		Ixazomib	C14H19BCl2N2O4	25183872	Moderate		Inter Info	[23], [24], [25]
D0900		Leflunomide	C12H9F3N2O2	3899	Moderate		Inter Info	[23], [24], [25]
D0918		Levodopa	C9H11NO4	6047	Moderate		Inter Info	[23], [24], [25]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[23], [24], [25]
D1051		Metronidazole	C6H9N3O3	4173	Moderate		Inter Info	[23], [24], [25]
D1113		Naxitamab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1118		Nelarabine	C11H15N5O5	3011155	Moderate		Inter Info	[23], [24], [25]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Moderate		Inter Info	[23], [24], [25]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[23], [24], [25]
D1212		Paclitaxel	C47H51NO14	36314	Moderate		Inter Info	[23], [24], [25]
D1213		Paclitaxel (protein-bound)	C47H51NO14	36314	Moderate		Inter Info	[23], [24], [25]
D1301		Pitavastatin	C25H24FNO4	5282452	Moderate		Inter Info	[23], [24], [25]
D1306		Polatuzumab vedotin	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1312		Pomalidomide	C13H11N3O4	134780	Moderate		Inter Info	[23], [24], [25]
D1313		Ponatinib	C29H27F3N6O	24826799	Moderate		Inter Info	[23], [24], [25]
D1430		Rosuvastatin	C22H28FN3O6S	446157	Moderate		Inter Info	[23], [24], [25]
D1452		Secnidazole	C7H11N3O3	71815	Moderate		Inter Info	[23], [24], [25]
D1473		Simvastatin	C25H38O5	54454	Moderate		Inter Info	[23], [24], [25]
D1479		Sodium aurothiomalate	C4H3AuNa2O4S	22318	Moderate		Inter Info	[23], [24], [25]
D1504		Stavudine	C10H12N2O4	18283	Moderate		Inter Info	[23], [24], [25]
D1543		Telbivudine	C10H14N2O5	159269	Moderate		Inter Info	[23], [24], [25]
D1551		Teniposide	C32H32O13S	452548	Moderate		Inter Info	[23], [24], [25]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Moderate		Inter Info	[23], [24], [25]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[27], [7], [1], [146]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[23], [24], [25]
D1599		Tocilizumab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1615		Trabectedin	C39H43N3O11S	108150	Moderate		Inter Info	[23], [24], [25]
D1623		Trastuzumab emtansine	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1697		Vinblastine	C46H58N4O9	13342	Moderate		Inter Info	[23], [24], [25]
D1698		Vincristine	C46H56N4O10	5978	Moderate		Inter Info	[23], [24], [25]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Moderate		Inter Info	[23], [24], [25]
D1700		Vinorelbine	C45H54N4O8	5311497	Moderate		Inter Info	[23], [24], [25]
D1714		Zafirlukast	C31H33N3O6S	5717	Moderate		Inter Info	[23], [24], [25]
D1715		Zalcitabine	C9H13N3O3	24066	Moderate		Inter Info	[27], [150]
D0614		Etanercept	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0802		Infliximab	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0821		Interferon alfa-2a, Recombinant	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0822		Interferon alfa-2b	C16H17Cl3I2N3NaO5S	71306834	Moderate		Inter Info	[23], [24], [25]
D0824		Interferon alfa-n1	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0823		Interferon alfacon-1	NA	NA	Moderate		Inter Info	[23], [24], [25]
D0956		Lovastatin	C24H36O5	53232	Moderate		Inter Info	[23], [24], [25]
D1237		Peginterferon alfa-2a	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1238		Peginterferon alfa-2b	NA	NA	Moderate		Inter Info	[23], [24], [25]
D1329		Pravastatin	C23H36O7	54687	Moderate		Inter Info	[23], [24], [25]
	Increased risk of photosensitivity reactions					Drug Num: 6
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0062		Aminolevulinic acid	C5H9NO3	137	Major		Inter Info	[3], [4]
D0063		Aminolevulinic acid (topical)	C5H9NO3	137	Moderate		Inter Info	[7], [1], [58]
D1028		Methoxsalen	C12H8O4	4114	Moderate		Inter Info	[7], [106], [3], [107], [108]
D1033		Methyl aminolevulinate (topical)	C6H11NO3	157922	Moderate		Inter Info	[7], [1], [58]
D1314		Porfimer sodium	C68H74N8O11	135577896	Moderate		Inter Info	[119], [1], [120]
D1691		Verteporfin	C82H84N8O16	11980904	Moderate		Inter Info	[1], [106], [3], [148]
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1914		Typhoid vaccine (live)	NA	NA	Major		Inter Info	[1], [20], [21]
D1693		Vibrio cholerae CVD 103-HgR strain live antigen (live)	NA	NA	Major		Inter Info	[22]
	Attenuated pharmacological effects (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1287		Picosulfuric acid	C18H15NO8S2	5243	Moderate		Inter Info	[116], [117], [118]

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163	Product Information. Nuvigil (armodafinil). Cephalon Inc, West Chester, PA.
164	Product Information. Provigil (modafinil). Cephalon, Inc, West Chester, PA.
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