Details of Drug

Drug General Information (ID: D0141)
Drug Name	Bacampicillin
Drug Type	Small molecule
Drug Synonymous	Bacampicilina; Bacampicilline; Bacampicillinum; Penglobe; Bacampicillin hydrochloride; Bacampicilina [INN-Spanish]; Bacampicillin (INN); Bacampicillin [INN:BAN]; Bacampicilline [INN-French]; Bacampicillinum [INN-Latin]; Penglobe (TN); Spectrobid (TN); (2S,5R,6R)-6((R)-(2-Amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid ester with ethyl 1-hydroxyethylcarbonate; 1'-Ethoxycarbonyloxyethyl-(6-D-alpha-aminophenylacetamido)penicillanate; 1-Ethoxycarbonyloxyethyl (2S,5R,6R)-6((R)-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptan-2-carboxylat; 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 1-[(ethoxycarbonyl)oxy]ethyl 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate; 1-ethoxycarbonyloxyethyl (2S,5R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2S)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 6-((R)-2-Amino-2-phenylacetamido)penicillansaeure-(1-(ethoxycarbonyloxy)ethylester Click to Show/Hide
Disease Class	1A00-1C4Z: Bacterial infection
Therapeutic Class	Antibiotics
Structure
Structure	3D Structure		2D Structure
Formula	C21H27N3O7S
InChI	1S/C21H27N3O7S/c1-5-29-20(28)31-11(2)30-19(27)15-21(3,4)32-18-14(17(26)24(15)18)23-16(25)13(22)12-9-7-6-8-10-12/h6-11,13-15,18H,5,22H2,1-4H3,(H,23,25)/t11?,13-,14-,15+,18-/m1/s1
InChIKey	PFOLLRNADZZWEX-FFGRCDKISA-N
Canonical SMILES	CCOC(=O)OC(C)OC(=O)C1C(SC2N1C(=O)C2NC(=O)C(C3=CC=CC=C3)N)(C)C
External Link
	Pubchem ID	441397
	CAS Number	50972-17-3
	CHEBI ID	2968
	TTD ID	D04CFW

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM003 Affected organization distribution AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM002 Altered intestinal flora BM003 Complex formation BM005 Altered gastric pH BM014 Interference of cell/tissue uptake BM028 Competitive inhibition of renal tubular secretion BM050 Increased risk of bleeding BM068 Increased risk of intestinal flora disorders BM079 Increased risk of skin rash BM100 Antagonize the effect of vaccine/toxoid BM107 Attenuated pharmacological effects (Unspecific)
Relation Graph

Full list of drugs interacting with Bacampicillin
Affected gastrointestinal absorption
	Altered intestinal flora					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1094		Mycophenolate mofetil	C23H31NO7	5281078	Moderate		Inter Info	[32], [33]
D1095		Mycophenolic acid	C17H20O6	446541	Moderate		Inter Info	[32], [33]
	Complex formation					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1369		Quinapril	C25H30N2O5	54892	Moderate		Inter Info	[1], [35]
	Altered gastric pH					Drug Num: 18
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0049		Aluminum hydroxide	AlH3O3	10176082	Moderate		Inter Info	[15], [16]
D0236		Calcium carbonate	CCaO3	10112	Moderate		Inter Info	[15], [16]
D0458		Dexlansoprazole	C16H14F3N3O2S	9578005	Moderate		Inter Info	[15], [16]
D0968		Magnesium carbonate	CMgO3	11029	Moderate		Inter Info	[15], [16]
D0973		Magnesium hydroxide	H2MgO2	14791	Moderate		Inter Info	[15], [16]
D1483		Sodium citrate	C6H5Na3O7	6224	Moderate		Inter Info	[15], [16]
D0337		Cimetidine	C10H16N6S	2756	Moderate		Inter Info	[15], [16]
D0483		Didanosine	C10H12N4O3	135398739	Moderate		Inter Info	[15], [16]
D0603		Esomeprazole	C17H19N3O3S	9568614	Moderate		Inter Info	[15], [16]
D0636		Famotidine	C8H15N7O2S3	5702160	Moderate		Inter Info	[15], [16]
D0892		Lansoprazole	C16H14F3N3O2S	3883	Moderate		Inter Info	[15], [16]
D0974		Magnesium oxide	MgO	14792	Moderate		Inter Info	[15], [16]
D1151		Nizatidine	C12H21N5O2S2	3033637	Moderate		Inter Info	[15], [16]
D1179		Omeprazole	C17H19N3O3S	4594	Moderate		Inter Info	[15], [16]
D1222		Pantoprazole	C16H15F2N3O4S	4679	Moderate		Inter Info	[15], [16]
D1373		Rabeprazole	C18H21N3O3S	5029	Moderate		Inter Info	[15], [16]
D1381		Ranitidine	C13H22N4O3S	3001055	Moderate		Inter Info	[15], [16]
D1480		Sodium bicarbonate	CHNaO3	516892	Moderate		Inter Info	[15], [16]
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1817		Indium In-111 oxyquinoline	C27H18InN3O3	16685037	Moderate		Inter Info	[17]
D1822		Iodide I-123	I-	135300	Moderate		Inter Info	[18], [19], [20]
Affected excretion pathways
	Competitive inhibition of renal tubular secretion					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1025		Methotrexate	C20H22N8O5	126941	Major		Inter Info	[5], [6], [7], [8], [9], [10], [11], [12], [13], [14]
D0576		Entecavir	C12H15N5O3	135398508	Moderate		Inter Info	[28]
D1241		Pemetrexed	C20H21N5O6	135410875	Moderate		Inter Info	[34]
D1341		Probenecid	C13H19NO4S	4911	Minor		Inter Info	[57], [58], [59], [60], [61], [62]
Pharmacodynamic additive effects
	Increased risk of bleeding					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52]
	Increased risk of intestinal flora disorders					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0354		Clindamycin	C18H33ClN2O5S	446598	Minor		Inter Info	[56]
	Increased risk of skin rash					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0040		Allopurinol	C5H4N4O	135401907	Minor		Inter Info	[53], [54], [55]
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1914		Typhoid vaccine (live)	NA	NA	Major		Inter Info	[1], [2], [3]
D1693		Vibrio cholerae CVD 103-HgR strain live antigen (live)	NA	NA	Major		Inter Info	[4]
	Attenuated pharmacological effects (Unspecific)					Drug Num: 10
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1287		Picosulfuric acid	C18H15NO8S2	5243	Moderate		Inter Info	[21], [22], [23]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[24], [25], [26]
D0145		Balsalazide	C17H15N3O6	54585	Moderate		Inter Info	[27]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[24], [25], [26]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[24], [25], [26]
D0606		Estradiol	C18H24O2	5757	Moderate		Inter Info	[29], [30], [31]
D0619		Ethinylestradiol	C20H24O2	5991	Moderate		Inter Info	[29], [30], [31]
D1011		Mestranol	C21H26O2	6291	Moderate		Inter Info	[29], [30], [31]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[24], [25], [26]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[24], [25], [26]

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