Drug General Information (ID: DDIE9ANHSJ)
  Drug Name Clindamycin Drug Info Bacampicillin Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Antibiotics Antibiotics
  Structure

 Mechanism of Clindamycin-Bacampicillin Interaction (Severity Level: Minor)
     Increased risk of intestinal flora disorders Click to Show/Hide Mechanism Graph
      Drug Name Clindamycin Bacampicillin
      Mechanism Intestinal flora disorders Intestinal flora disorders
      Key Mechanism Factor 1
Factor Name Intestinal flora disorders
Factor Description Maintaining the balance of intestinal flora is important for human health. Disturbed intestinal flora may lead to constipation, diarrhea, lowered immunity and other age-related diseases.
      Mechanism Description
  • Increased risk of intestinal flora disorders by the combination of Clindamycin and Bacampicillin 

References
1 Brause BD, Romankiewicz JA, Gotz V, Franklin JE Jr, Roberts RB "Comparative study of diarrhea associated with clindamycin and ampicillin therapy." Am J Gastroenterol 73 (1980): 244-8. [PMID: 7405925]