Drug General Information (ID: D0107)
  Drug Name
Arsenic trioxide
  Drug Type Small molecule
  Drug Synonymous
Arsenox; Arsentrioxide; Naonobin; Trisenox; Trixenox; Acide arsenieux [French]; Anhydride arsenieux [French]; Arseni trioxydum; Arsenic blanc [French]; Arsenic trioxide [JAN]; Arsenigen saure [German]; Arsenious Acid Anhydride; Arsenious trioxide; Arsenous oxide [ISO]; Oxyde Arsenieux; Arsenic trioxide [UN1561] [Poison]; Arsenic oxide (As2O3); Arsenic(III) trioxide; Oxyde Arsenieux [ISO-French]; Trisenox (TN); Arsenic trioxide (JP15/USAN); Arsenic(3+)
    Click to Show/Hide
  Disease Class 2A85: Mature B-cell lymphoma
  Therapeutic Class Antineoplastics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula As2O3
  InChI 1S/2As.3O/q2*+3;3*-2
  InChIKey QTLQKAJBUDWPIB-UHFFFAOYSA-N
  Canonical SMILES [O-2].[O-2].[O-2].[As+3].[As+3]
  External Link
Pubchem ID 14888
CAS Number 1327-53-3
TTD ID D07VIK
VARIDT ID DR00119

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM044  Additive myelosuppressive effects
BM076  Increased risk of prolong QT interval
BM081  Increased risk of ventricular arrhythmias
BM107  Attenuated pharmacological effects (Unspecific)
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Arsenic trioxide
      Pharmacodynamic additive effects
   Additive myelosuppressive effects Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0433
 
Deferiprone
 
C7H9NO2
 
2972 
Major    Inter Info   
[12], [13], [14]
   Increased risk of prolong QT interval Drug Num:  25
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0003
 
Abarelix
 
C72H95ClN14O14
 
16131215 
Major    Inter Info   
[1], [2]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Major    Inter Info   
[15], [16], [12], [4], [17], [18], [19]
D0749
 
Halofantrine
 
C26H30Cl2F3NO
 
37393 
Major    Inter Info   
[22], [15], [12], [4], [23], [24], [25], [26], [27]
D0909
 
Levacetylmethadol
 
C23H31NO2
 
15130 
Major    Inter Info   
[4], [30], [19]
D0960
 
Lumefantrine
 
C30H32Cl3NO
 
6437380 
Major    Inter Info   
[12], [4], [31]
D0965
 
Macimorelin
 
C26H30N6O3
 
9804938 
Major    Inter Info   
[32]
D1444
 
Saquinavir
 
C38H50N6O5
 
441243 
Major    Inter Info   
[37], [38], [15], [12], [4], [39], [40]
D1499
 
Sparfloxacin
 
C19H22F2N4O3
 
60464 
Major    Inter Info   
[42], [15], [12], [4], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Major    Inter Info   
[15], [12], [4], [60], [61], [19], [21]
D0554
 
Efavirenz
 
C14H9ClF3NO2
 
64139 
Major    Inter Info   
[62]
D0740
 
Grepafloxacin
 
C19H22FN3O3
 
72474 
Major    Inter Info   
[42], [15], [12], [4], [63], [64], [58]
D1010
 
Mesoridazine
 
C21H26N2OS2
 
4078 
Major    Inter Info   
[15], [12], [4], [68], [19]
D1063
 
Mifepristone
 
C29H35NO2
 
55245 
Major    Inter Info   
[15], [12], [4], [69]
D1223
 
Papaverine
 
C20H21NO4
 
4680 
Major    Inter Info   
[70], [71], [72], [73], [74], [75], [76], [77]
D1254
 
Perflutren
 
C3F8
 
6432 
Major    Inter Info   
[78], [79]
D1292
 
Pimozide
 
C28H29F2N3O
 
16362 
Major    Inter Info   
[4], [80], [81], [19]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Major    Inter Info   
[15], [12], [4], [106], [80], [107], [108], [109], [19]
D1726
 
Ziprasidone
 
C21H21ClN4OS
 
60854 
Major    Inter Info   
[15], [12], [4], [80], [110], [19]
D0105
 
Aripiprazole
 
C23H27Cl2N3O2
 
60795 
Moderate    Inter Info   
[12], [4], [114], [115], [116], [117], [118], [119]
D0636
 
Famotidine
 
C8H15N7O2S3
 
5702160 
Moderate    Inter Info   
[12], [4], [129]
D0947
 
Loperamide
 
C29H33ClN2O2
 
3955 
Moderate    Inter Info   
[133], [134]
D1166
 
Olanzapine
 
C17H20N4S
 
135398745 
Moderate    Inter Info   
[12], [4], [135]
D1356
 
Propofol
 
C12H18O
 
4943 
Moderate    Inter Info   
[138], [139], [140], [141], [142], [143], [144], [145], [146], [147]
D1051
 
Metronidazole
 
C6H9N3O3
 
4173 
Minor    Inter Info   
[12], [149], [150], [151]
D1516
 
Sulfamethoxazole
 
C10H11N3O3S
 
5329 
Minor    Inter Info   
[15], [12], [4], [152], [153], [154], [155]
   Increased risk of ventricular arrhythmias Drug Num:  223
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0012
 
Acetazolamide
 
C4H6N4O3S2
 
1986 
Major    Inter Info   
[1], [2]
D0025
 
Adenosine
 
C10H13N5O4
 
60961 
Major    Inter Info   
[3], [4], [5], [6], [7], [8], [9], [10]
D0036
 
Alfuzosin
 
C19H27N5O4
 
2092 
Major    Inter Info   
[1], [2]
D0066
 
Amiodarone
 
C25H29I2NO3
 
2157 
Major    Inter Info   
[1], [2]
D0068
 
Amitriptyline
 
C20H23N
 
2160 
Major    Inter Info   
[1], [2]
D0072
 
Amoxapine
 
C17H16ClN3O
 
2170 
Major    Inter Info   
[1], [2]
D0075
 
Amphotericin B
 
C47H73NO17
 
5280965 
Major    Inter Info   
[1], [2]
D0076
 
Amphotericin B (cholesteryl sulfate)
 
C47H73NO17
 
5280965 
Major    Inter Info   
[1], [2]
D0077
 
Amphotericin B (lipid complex)
 
C47H73NO17
 
5280965 
Major    Inter Info   
[1], [2]
D0078
 
Amphotericin B (liposomal)
 
C47H73NO17
 
5280965 
Major    Inter Info   
[1], [2]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Major    Inter Info   
[1], [2]
D0097
 
Apomorphine
 
C17H17NO2
 
6005 
Major    Inter Info   
[1], [2]
D0007
 
Abiraterone
 
C24H31NO
 
132971 
Major    Inter Info   
[1], [2]
D0037
 
Alimemazine
 
C18H22N2S
 
5574 
Major    Inter Info   
[1], [11], [2]
D0067
 
Amisulpride
 
C17H27N3O4S
 
2159 
Major    Inter Info   
[1], [2]
D0095
 
Apalutamide
 
C21H15F4N5O2S
 
24872560 
Major    Inter Info   
[1], [2]
D0112
 
Asenapine
 
C17H16ClNO
 
3036780 
Major    Inter Info   
[1], [2]
D0149
 
Bedaquiline
 
C32H31BrN2O2
 
5388906 
Major    Inter Info   
[1], [2]
D0170
 
Bepridil
 
C24H34N2O
 
2351 
Major    Inter Info   
[1], [2]
D0195
 
Bosutinib
 
C26H29Cl2N5O3
 
5328940 
Major    Inter Info   
[1], [2]
D0230
 
Cabozantinib
 
C28H24FN3O5
 
25102847 
Major    Inter Info   
[1], [2]
D0349
 
Clarithromycin
 
C38H69NO13
 
84029 
Major    Inter Info   
[1], [2]
D0361
 
Clomipramine
 
C19H23ClN2
 
2801 
Major    Inter Info   
[1], [2]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Major    Inter Info   
[1], [2]
D0437
 
Degarelix
 
C82H103ClN18O16
 
16136245 
Major    Inter Info   
[1], [2]
D0452
 
Deutetrabenazine
 
C19H27NO3
 
73437646 
Major    Inter Info   
[1], [2]
D0569
 
Encorafenib
 
C22H27ClFN7O4S
 
50922675 
Major    Inter Info   
[1], [2]
D0577
 
Entrectinib
 
C31H34F2N6O2
 
25141092 
Major    Inter Info   
[1], [2]
D0578
 
Enzalutamide
 
C21H16F4N4O2S
 
15951529 
Major    Inter Info   
[1], [2]
D0594
 
Eribulin
 
C40H59NO11
 
11354606 
Major    Inter Info   
[1], [2]
D0632
 
Ezogabine
 
C16H18FN3O2
 
121892 
Major    Inter Info   
[1], [2]
D0661
 
Fingolimod
 
C19H33NO2
 
107970 
Major    Inter Info   
[15], [12], [4], [20], [21]
D0664
 
Flecainide
 
C17H20F6N2O3
 
3356 
Major    Inter Info   
[1], [2]
D0700
 
Fostemsavir
 
C25H26N7O8P
 
11319217 
Major    Inter Info   
[1], [2]
D0720
 
Gilteritinib
 
C29H44N8O3
 
49803313 
Major    Inter Info   
[1], [2]
D0725
 
Glasdegib
 
C21H22N6O
 
25166913 
Major    Inter Info   
[1], [2]
D0758
 
Histrelin
 
C66H86N18O12
 
25077993 
Major    Inter Info   
[1], [2]
D0779
 
Hydroxychloroquine
 
C18H26ClN3O
 
3652 
Major    Inter Info   
[1], [2]
D0788
 
Idarubicin
 
C26H27NO9
 
42890 
Major    Inter Info   
[1], [2]
D0791
 
Iloperidone
 
C24H27FN2O4
 
71360 
Major    Inter Info   
[1], [2]
D0868
 
Ivabradine
 
C27H36N2O5
 
132999 
Major    Inter Info   
[4], [28], [29]
D0872
 
Ivosidenib
 
C28H22ClF3N6O3
 
71657455 
Major    Inter Info   
[1], [2]
D0894
 
Lapatinib
 
C29H26ClFN4O4S
 
208908 
Major    Inter Info   
[1], [2]
D0899
 
Lefamulin
 
C28H45NO5S
 
25185057 
Major    Inter Info   
[1], [2]
D0903
 
Lenvatinib
 
C21H19ClN4O4
 
9823820 
Major    Inter Info   
[1], [2]
D0937
 
Lisdexamfetamine
 
C15H25N3O
 
11597698 
Major    Inter Info   
[1], [2]
D0942
 
Lofexidine
 
C11H12Cl2N2O
 
30668 
Major    Inter Info   
[1], [2]
D0948
 
Lopinavir
 
C37H48N4O5
 
92727 
Major    Inter Info   
[1], [11], [2]
D1026
 
Methotrimeprazine
 
C19H24N2OS
 
72287 
Major    Inter Info   
[1], [2]
D1062
 
Midostaurin
 
C35H30N4O4
 
9829523 
Major    Inter Info   
[1], [2]
D1136
 
Nilotinib
 
C28H22F3N7O
 
644241 
Major    Inter Info   
[1], [2]
D1169
 
Oliceridine
 
C22H30N2O2S
 
66553195 
Major    Inter Info   
[1], [2]
D1189
 
Osilodrostat
 
C13H10FN3
 
44139752 
Major    Inter Info   
[1], [2]
D1190
 
Osimertinib
 
C28H33N7O2
 
71496458 
Major    Inter Info   
[1], [2]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Major    Inter Info   
[33]
D1215
 
Paliperidone
 
C23H27FN4O3
 
115237 
Major    Inter Info   
[1], [2]
D1220
 
Panitumumab
 
NA
 
NA
Major    Inter Info   
[1], [2]
D1221
 
Panobinostat
 
C21H23N3O2
 
6918837 
Major    Inter Info   
[1], [2]
D1230
 
Pasireotide
 
C58H66N10O9
 
9941444 
Major    Inter Info   
[1], [2]
D1231
 
Patiromer
 
NA
 
NA
Major    Inter Info   
[1], [2]
D1232
 
Pazopanib
 
C21H23N7O2S
 
10113978 
Major    Inter Info   
[1], [2]
D1287
 
Picosulfuric acid
 
C18H15NO8S2
 
5243 
Major    Inter Info   
[34], [35], [36]
D1290
 
Pimavanserin
 
C25H34FN3O2
 
10071196 
Major    Inter Info   
[1], [2]
D1302
 
Pitolisant
 
C17H26ClNO
 
9948102 
Major    Inter Info   
[1], [2]
D1308
 
Polyethylene glycol (3350 with electrolytes)
 
C2H6O2
 
174 
Major    Inter Info   
[34], [35], [36]
D1311
 
Polythiazide
 
C11H13ClF3N3O4S3
 
4870 
Major    Inter Info   
[1], [2]
D1315
 
Posaconazole
 
C37H42F2N8O4
 
468595 
Major    Inter Info   
[1], [2]
D1342
 
Probucol
 
C31H48O2S2
 
4912 
Major    Inter Info   
[1], [2]
D1353
 
Propafenone
 
C21H27NO3
 
4932 
Major    Inter Info   
[1], [2]
D1368
 
Quetiapine
 
C21H25N3O2S
 
5002 
Major    Inter Info   
[1], [2]
D1398
 
Ribociclib
 
C23H30N8O
 
44631912 
Major    Inter Info   
[1], [2]
D1404
 
Rilpivirine
 
C22H18N6
 
6451164 
Major    Inter Info   
[1], [2]
D1424
 
Romidepsin
 
C24H36N4O6S2
 
5352062 
Major    Inter Info   
[1], [2]
D1432
 
Rucaparib
 
C19H18FN3O
 
9931954 
Major    Inter Info   
[1], [2]
D1459
 
Selpercatinib
 
C29H31N7O3
 
134436906 
Major    Inter Info   
[1], [2]
D1463
 
Sevoflurane
 
C4H3F7O
 
5206 
Major    Inter Info   
[1], [2]
D1474
 
Siponimod
 
C29H35F3N2O3
 
44599207 
Major    Inter Info   
[12], [41]
D1488
 
Sodium sulfate
 
Na2O4S
 
24436 
Major    Inter Info   
[34], [35], [36]
D1491
 
Solifenacin
 
C23H26N2O2
 
154059 
Major    Inter Info   
[1], [2]
D1522
 
Sunitinib
 
C22H27FN4O2
 
5329102 
Major    Inter Info   
[1], [2]
D1542
 
Telavancin
 
C80H106Cl2N11O27P
 
3081362 
Major    Inter Info   
[1], [2]
D1560
 
Tetrabenazine
 
C19H27NO3
 
6018 
Major    Inter Info   
[1], [2]
D1605
 
Tolevamer
 
C11H16O3S
 
58817179 
Major    Inter Info   
[1], [2]
D1634
 
Triclabendazole
 
C14H9Cl3N2OS
 
50248 
Major    Inter Info   
[1], [2]
D1651
 
Triptorelin
 
C64H82N18O13
 
25074470 
Major    Inter Info   
[1], [2]
D1681
 
Vandetanib
 
C22H24BrFN4O2
 
3081361 
Major    Inter Info   
[1], [2]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Major    Inter Info   
[1], [2]
D0115
 
Astemizole
 
C28H31FN4O
 
2247 
Major    Inter Info   
[1], [2]
D0119
 
Atomoxetine
 
C17H21NO
 
54841 
Major    Inter Info   
[1], [2]
D0139
 
Azithromycin
 
C38H72N2O12
 
447043 
Major    Inter Info   
[1], [2]
D0158
 
Bendroflumethiazide
 
C15H14F3N3O4S2
 
2315 
Major    Inter Info   
[1], [2]
D0166
 
Benzthiazide
 
C15H14ClN3O4S3
 
2343 
Major    Inter Info   
[1], [2]
D0180
 
Bicalutamide
 
C18H14F4N2O4S
 
2375 
Major    Inter Info   
[1], [2]
D0217
 
Bumetanide
 
C17H20N2O5S
 
2471 
Major    Inter Info   
[1], [2]
D0219
 
Buprenorphine
 
C29H41NO4
 
644073 
Major    Inter Info   
[1], [2]
D0252
 
Capreomycin
 
C50H88N28O15
 
3000502 
Major    Inter Info   
[1], [2]
D0320
 
Chloroquine
 
C18H26ClN3
 
2719 
Major    Inter Info   
[1], [2]
D0321
 
Chlorothiazide
 
C7H6ClN3O4S2
 
2720 
Major    Inter Info   
[1], [2]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Major    Inter Info   
[1], [2]
D0326
 
Chlorthalidone
 
C14H11ClN2O4S
 
2732 
Major    Inter Info   
[1], [2]
D0336
 
Cilostazol
 
C20H27N5O2
 
2754 
Major    Inter Info   
[1], [2]
D0341
 
Ciprofloxacin
 
C17H18FN3O3
 
2764 
Major    Inter Info   
[1], [2]
D0342
 
Cisapride
 
C23H29ClFN3O4
 
6917698 
Major    Inter Info   
[1], [2]
D0344
 
Cisplatin
 
Cl2H6N2Pt
 
5702198 
Major    Inter Info   
[1], [2]
D0358
 
Clofazimine
 
C27H22Cl2N4
 
2794 
Major    Inter Info   
[1], [2]
D0429
 
Daunorubicin
 
C27H29NO10
 
30323 
Major    Inter Info   
[1], [2]
D0430
 
Daunorubicin (liposomal)
 
C27H29NO10
 
30323 
Major    Inter Info   
[1], [11], [2]
D0446
 
Desipramine
 
C18H22N2
 
2995 
Major    Inter Info   
[1], [2]
D0479
 
Diclofenamide
 
C6H6Cl2N2O4S2
 
3038 
Major    Inter Info   
[1], [2]
D0492
 
Digoxin Immune Fab (Ovine)
 
NA
 
NA
Major    Inter Info   
[1], [2]
D0508
 
Disopyramide
 
C21H29N3O
 
3114 
Major    Inter Info   
[1], [2]
D0513
 
Dofetilide
 
C19H27N3O5S2
 
71329 
Major    Inter Info   
[1], [2]
D0514
 
Dolasetron
 
C19H20N2O3
 
3033818 
Major    Inter Info   
[1], [2]
D0525
 
Doxepin
 
C19H21NO
 
667477 
Major    Inter Info   
[1], [2]
D0526
 
Doxepin (topical)
 
C19H21NO
 
667477 
Major    Inter Info   
[1], [11], [2]
D0528
 
Doxorubicin
 
C27H29NO11
 
31703 
Major    Inter Info   
[1], [2]
D0529
 
Doxorubicin (liposomal)
 
C27H29NO11
 
31703 
Major    Inter Info   
[1], [11], [2]
D0535
 
Droperidol
 
C22H22FN3O2
 
3168 
Major    Inter Info   
[1], [2]
D0584
 
Epirubicin
 
C27H29NO11
 
41867 
Major    Inter Info   
[1], [2]
D0597
 
Erythromycin
 
C37H67NO13
 
12560 
Major    Inter Info   
[1], [2]
D0613
 
Etacrynic acid
 
C13H12Cl2O4
 
3278 
Major    Inter Info   
[1], [2]
D0644
 
Fenoldopam
 
C16H16ClNO3
 
3341 
Major    Inter Info   
[1], [2]
D0667
 
Fluconazole
 
C13H12F2N6O
 
3365 
Major    Inter Info   
[1], [2]
D0671
 
Fludrocortisone
 
C21H29FO5
 
31378 
Major    Inter Info   
[1], [2]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Major    Inter Info   
[1], [2]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Major    Inter Info   
[1], [2]
D0682
 
Flutamide
 
C11H11F3N2O3
 
3397 
Major    Inter Info   
[1], [2]
D0694
 
Foscarnet
 
CH3O5P
 
3415 
Major    Inter Info   
[1], [2]
D0704
 
Furosemide
 
C12H11ClN2O5S
 
3440 
Major    Inter Info   
[1], [2]
D0712
 
Gatifloxacin
 
C19H22FN3O4
 
5379 
Major    Inter Info   
[1], [2]
D0716
 
Gemifloxacin
 
C18H20FN5O4
 
9571107 
Major    Inter Info   
[1], [2]
D0737
 
Goserelin
 
C59H84N18O14
 
5311128 
Major    Inter Info   
[1], [2]
D0738
 
Granisetron
 
C18H24N4O
 
5284566 
Major    Inter Info   
[1], [2]
D0750
 
Haloperidol
 
C21H23ClFNO2
 
3559 
Major    Inter Info   
[1], [2]
D0751
 
Halothane
 
C2HBrClF3
 
3562 
Major    Inter Info   
[1], [2]
D0771
 
Hydrochlorothiazide
 
C7H8ClN3O4S2
 
3639 
Major    Inter Info   
[1], [2]
D0773
 
Hydrocortisone
 
C21H30O5
 
5754 
Major    Inter Info   
[1], [2]
D0775
 
Hydroflumethiazide
 
C8H8F3N3O4S2
 
3647 
Major    Inter Info   
[1], [2]
D0781
 
Hydroxyzine
 
C21H27ClN2O2
 
3658 
Major    Inter Info   
[1], [2]
D0787
 
Ibutilide
 
C20H36N2O3S
 
60753 
Major    Inter Info   
[1], [2]
D0795
 
Imipramine
 
C19H24N2
 
3696 
Major    Inter Info   
[1], [2]
D0798
 
Indapamide
 
C16H16ClN3O3S
 
3702 
Major    Inter Info   
[1], [2]
D0859
 
Isoprenaline
 
C11H17NO3
 
3779 
Major    Inter Info   
[65], [66], [67]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Major    Inter Info   
[1], [2]
D0908
 
Leuprolide
 
C59H84N16O12
 
657181 
Major    Inter Info   
[1], [2]
D0919
 
Levofloxacin
 
C18H20FN3O4
 
149096 
Major    Inter Info   
[1], [2]
D0943
 
Lomefloxacin
 
C17H19F2N3O3
 
3948 
Major    Inter Info   
[1], [2]
D0979
 
Maprotiline
 
C20H23N
 
4011 
Major    Inter Info   
[1], [2]
D0992
 
Mefloquine
 
C17H16F6N2O
 
4046 
Major    Inter Info   
[1], [2]
D1017
 
Methadone
 
C21H27NO
 
4095 
Major    Inter Info   
[1], [2]
D1018
 
Methazolamide
 
C5H8N4O3S2
 
4100 
Major    Inter Info   
[1], [2]
D1048
 
Metolazone
 
C16H16ClN3O3S
 
4170 
Major    Inter Info   
[1], [2]
D1075
 
Mirtazapine
 
C17H19N3
 
4205 
Major    Inter Info   
[1], [2]
D1092
 
Moxifloxacin
 
C21H24FN3O4
 
152946 
Major    Inter Info   
[1], [2]
D1137
 
Nilutamide
 
C12H10F3N3O4
 
4493 
Major    Inter Info   
[1], [2]
D1155
 
Norfloxacin
 
C16H18FN3O3
 
4539 
Major    Inter Info   
[1], [2]
D1158
 
Nortriptyline
 
C19H21N
 
4543 
Major    Inter Info   
[1], [2]
D1165
 
Ofloxacin
 
C18H20FN3O4
 
4583 
Major    Inter Info   
[1], [2]
D1181
 
Ondansetron
 
C18H19N3O
 
4595 
Major    Inter Info   
[1], [2]
D1185
 
Orciprenaline
 
C11H17NO3
 
4086 
Major    Inter Info   
[65], [66], [67]
D1210
 
Oxytocin
 
C43H66N12O12S2
 
439302 
Major    Inter Info   
[1], [2]
D1216
 
Palonosetron
 
C19H24N2O
 
6337614 
Major    Inter Info   
[1], [2]
D1246
 
Pentamidine
 
C19H24N4O2
 
4735 
Major    Inter Info   
[1], [2]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Major    Inter Info   
[1], [2]
D1339
 
Primaquine
 
C15H21N3O
 
4908 
Major    Inter Info   
[1], [2]
D1343
 
Procainamide
 
C13H21N3O
 
4913 
Major    Inter Info   
[1], [2]
D1346
 
Prochlorperazine
 
C20H24ClN3S
 
4917 
Major    Inter Info   
[1], [2]
D1351
 
Promazine
 
C17H20N2S
 
4926 
Major    Inter Info   
[1], [2]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Major    Inter Info   
[1], [2]
D1371
 
Quinidine
 
C20H24N2O2
 
441074 
Major    Inter Info   
[1], [2]
D1372
 
Quinine
 
C20H24N2O2
 
3034034 
Major    Inter Info   
[1], [2]
D1383
 
Ranolazine
 
C24H33N3O4
 
56959 
Major    Inter Info   
[1], [2]
D1413
 
Risperidone
 
C23H27FN4O2
 
5073 
Major    Inter Info   
[1], [2]
D1414
 
Ritodrine
 
C17H21NO3
 
33572 
Major    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Major    Inter Info   
[1], [2]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Major    Inter Info   
[1], [2]
D1526
 
Tacrolimus
 
C44H69NO12
 
445643 
Major    Inter Info   
[1], [2]
D1533
 
Tamoxifen
 
C26H29NO
 
2733526 
Major    Inter Info   
[1], [2]
D1544
 
Telithromycin
 
C43H65N5O10
 
3002190 
Major    Inter Info   
[1], [2]
D1554
 
Terbutaline
 
C12H19NO3
 
5403 
Major    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D1555
 
Terfenadine
 
C32H41NO2
 
5405 
Major    Inter Info   
[1], [2]
D1596
 
Tizanidine
 
C9H8ClN5S
 
5487 
Major    Inter Info   
[1], [2]
D1611
 
Torasemide
 
C16H20N4O3S
 
41781 
Major    Inter Info   
[1], [2]
D1612
 
Toremifene
 
C26H28ClNO
 
3005573 
Major    Inter Info   
[1], [2]
D1616
 
Tramadol
 
C16H25NO2
 
33741 
Major    Inter Info   
[1], [2]
D1624
 
Trazodone
 
C19H22ClN5O
 
5533 
Major    Inter Info   
[1], [2]
D1633
 
Trichlormethiazide
 
C8H8Cl3N3O4S2
 
5560 
Major    Inter Info   
[1], [2]
D1637
 
Trifluoperazine
 
C21H24F3N3S
 
5566 
Major    Inter Info   
[1], [2]
D1638
 
Triflupromazine
 
C18H19F3N2S
 
5568 
Major    Inter Info   
[1], [2]
D1647
 
Trimipramine
 
C20H26N2
 
5584 
Major    Inter Info   
[1], [2]
D1682
 
Vardenafil
 
C23H32N6O4S
 
135400189 
Major    Inter Info   
[1], [2]
D1683
 
Vasopressin
 
C46H65N15O12S2
 
644077 
Major    Inter Info   
[1], [2]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Major    Inter Info   
[1], [2]
D1706
 
Voriconazole
 
C16H14F3N5O
 
71616 
Major    Inter Info   
[1], [2]
D0103
 
Arformoterol
 
C19H24N2O4
 
3083544 
Moderate    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [111], [112], [94], [95], [96], [97], [98], [113], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D0184
 
Bisacodyl
 
C22H19NO4
 
2391 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D0269
 
Castor oil
 
C57H104O9
 
14030006 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D0701
 
Frangula purshiana bark
 
NA
 
NA
Moderate    Inter Info   
[12], [4], [122]
D0731
 
Glycerin
 
C3H8O3
 
753 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D0797
 
Indacaterol
 
C24H28N2O3
 
6918554 
Moderate    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [111], [112], [94], [95], [96], [97], [98], [113], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D0887
 
Lactitol
 
C12H24O11
 
157355 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D0924
 
Levosalbutamol
 
C13H21NO3
 
123600 
Moderate    Inter Info   
[111], [100], [103]
D0970
 
Magnesium citrate
 
C12H10Mg3O14
 
6099959 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D0973
 
Magnesium hydroxide
 
H2MgO2
 
14791 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D0989
 
Mecobalamin
 
C63H91CoN13O14P
 
10898559 
Moderate    Inter Info   
[124], [125], [2]
D1069
 
Mineral oil
 
NA
 
NA
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D1171
 
Olodaterol
 
C21H26N2O5
 
11504295 
Moderate    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [111], [112], [94], [95], [96], [97], [98], [113], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D1266
 
Phenolphthalein
 
C20H14O4
 
4764 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D1298
 
Pirbuterol
 
C12H20N2O3
 
4845 
Moderate    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [111], [112], [94], [95], [96], [97], [98], [113], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D1309
 
Polyethylene glycol (3350)
 
C2H6O2
 
174 
Moderate    Inter Info   
[12], [4], [122]
D1695
 
Vilanterol
 
C24H33Cl2NO5
 
10184665 
Moderate    Inter Info   
[111], [100], [103]
D0395
 
Cyanocobalamin
 
C63H88CoN14O14P
 
5311498 
Moderate    Inter Info   
[124], [125], [2]
D0516
 
Donepezil
 
C24H29NO3
 
3152 
Moderate    Inter Info   
[15], [12], [4], [126], [127], [128]
D0691
 
Formoterol
 
C19H24N2O4
 
3410 
Moderate    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [111], [112], [94], [95], [96], [97], [98], [113], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D0707
 
Galantamine
 
C17H21NO3
 
9651 
Moderate    Inter Info   
[15], [12], [4], [126], [127], [128]
D0777
 
Hydroxocobalamin
 
C62H90CoN13O15P
 
70689311 
Moderate    Inter Info   
[124], [125], [2]
D0854
 
Isoetharine
 
C13H21NO3
 
3762 
Moderate    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [111], [112], [94], [95], [96], [97], [98], [113], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D0888
 
Lactulose
 
C12H22O11
 
11333 
Moderate    Inter Info   
[15], [12], [4], [120], [121], [122]
D1418
 
Rivastigmine
 
C14H22N2O2
 
77991 
Moderate    Inter Info   
[15], [12], [4], [126], [127], [128]
D1438
 
Salbutamol
 
C13H21NO3
 
2083 
Moderate    Inter Info   
[86], [92], [97]
D1440
 
Salmeterol
 
C25H37NO4
 
5152 
Moderate    Inter Info   
[65], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [111], [112], [94], [95], [96], [97], [98], [113], [99], [66], [100], [101], [102], [103], [67], [104], [105]
D1525
 
Tacrine
 
C13H14N2
 
1935 
Moderate    Inter Info   
[15], [12], [4], [126], [127], [128]
D1569
 
Thalidomide
 
C13H10N2O4
 
5426 
Moderate    Inter Info   
[12], [4], [148]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0789
 
Idelalisib
 
C22H18FN7O
 
11625818 
Moderate    Inter Info   
[123]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  3
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0659
 
Filgrastim
 
NA
 
NA
Moderate    Inter Info   
[130], [131], [132]
D1235
 
Pegfilgrastim
 
C27H46N4O19
 
70683024 
Moderate    Inter Info   
[136], [137]
D1446
 
Sargramostim
 
NA
 
NA
Moderate    Inter Info   
[130], [131], [132]
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94 Product Information. Brovana (arformoterol). Sepracor Inc, Marlborough, MA.
95 Product Information. Foradil (formoterol) Novartis Pharmaceuticals, East Hanover, NJ.
96 Product Information. Maxair (pirbuterol). 3M Pharmaceuticals, St. Paul, MN.
97 Product Information. Proventil (albuterol). Schering Laboratories, Kenilworth, NJ.
98 Product Information. Severent (salmeterol). Glaxo Wellcome, Research Triangle Park, NC.
99 Product Information. Xopenex (levalbuterol). Sepracor, Marlborough, MA.
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110 Product Information. Geodon (ziprasidone). Pfizer US Pharmaceuticals, New York, NY.
111 Product Information. Arcapta Neohaler (indacaterol). Novartis Pharmaceuticals, East Hanover, NJ.
112 Product Information. Breo Ellipta (fluticasone-vilanterol). GlaxoSmithKline, Research Triangle Park, NC.
113 Product Information. Striverdi Respimat (olodaterol). Boehringer Ingelheim, Ridgefield, CT.
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124 Product Information. Hydro-Cobex (hydroxocobalamin). Major Pharmaceuticals Inc, Rosemont, IL.
125 Product Information. Nascobol (cyanocobalamin nasal). Schwarz Pharma, Mequon, WI.
126 Product Information. Aricept (donepezil). Pfizer US Pharmaceuticals, New York, NY.
127 Product Information. Exelon (rivastigmine) Novartis Pharmaceuticals, East Hanover, NJ.
128 Product Information. Razadyne (galantamine). Johnson and Johnson Medical Inc, Arlington, TX.
129 Product Information. Pepcid (famotidine). Merck & Co, Inc, West Point, PA.
130 Product Information. Granix (tbo-filgrastim). Teva Pharmaceuticals USA, North Wales, PA.
131 Product Information. Leukine (sargramostim). Immunex Corporation, Seattle, WA.
132 Product Information. Stemgen (ancestim) Amgen, Thousand Oaks, CA.
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135 Product Information. Zyprexa (olanzapine). Lilly, Eli and Company, Indianapolis, IN.
136 Product Information. Brukinsa (zanubrutinib). BeiGene USA, Inc, San Mateo, CA.
137 Product Information. Neulasta (pegfilgrastim). Amgen, Thousand Oaks, CA.
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148 Product Information. Thalomid (thalidomide). Celgene Corporation, Warren, NJ.
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150 Product Information. Flagyl (metronidazole). Searle, Skokie, IL.
151 Product Information. Pylera (bismuth subcitrate potassium/metronidazo/TCN). Aptalis Pharma, Birmingham, AL.
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