Drug General Information (ID: DDINDXHQM9)
Drug Name			Triamcinolone (ophthalmic)		Drug Info		Isoniazid		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antiinflammatory Agents				Antitubercular Agents
Structure

Mechanism of Triamcinolone (ophthalmic)-Isoniazid Interaction (Severity Level: Minor)
Increased renal excretion (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Triamcinolone (ophthalmic)				Isoniazid
Mechanism		Increase the renal excretion of isoniazid				Isoniazid
Key Mechanism Factor 1
		Factor Name		Pharmacokinetics
		Factor Description		Alters the excretion of the drug, resulting in changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Increased renal excretion of Isoniazid caused by Triamcinolone (ophthalmic)

References
1	Dimartini A "Isoniazid, tricyclics and the ''cheese reaction''." Int Clin Psychopharmacol 10 (1995): 197-8. [PMID: 8675973]
2	Sarma G, Kailasam S, Nair NG, Narayana AS, Tripathy SP "Effect of prednisonlone and refampin on isoniazid metabolism in slow and rapid inactivators of isoniazid." Antimicrob Agents Chemother 18 (1980): 661-6
3	Brodie MJ, Boobis AR, Hillyard CJ, Abeyasekera G, MacIntyre I, Park BK "Effect of isoniazid on vitamin D metabolism and hepatic monooxygenase activity." Clin Pharmacol Ther 30 (1981): 363-7