Drug General Information (ID: DDIIVLW63E)
Drug Name			Paricalcitol		Drug Info		Iron sucrose		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Parasympathomimetics				Iron Supplement
Structure

Mechanism of Paricalcitol-Iron sucrose Interaction (Severity Level: Moderate)
Adsorption Click to Show/Hide Mechanism Graph
Drug Name		Paricalcitol				Iron sucrose
Mechanism		Adsorbed by sucroferric oxyhydroxide				Sucroferric oxyhydroxide
Key Mechanism Factor 1
		Factor Name		Adsorption
		Factor Description		Adsorption is a direct drug interaction, usually through adsorption on its surface, resulting in reduced absorption of concomitantly administered drugs in the gastrointestinal tract.
Mechanism Description		Decreased absorption of Paricalcitol due to adsorption of Iron sucrose

Recommended Action
Management		Oral formulations of vitamin D analogs should not be prescribed with sucroferric oxyhydroxide.

References
1	Product Information. Velphoro (sucroferric oxyhydroxide). Fresenius Medical Care North America, Lexington, MA.