Drug General Information (ID: DDI39HWK6P)
Drug Name			Cyanocobalamin		Drug Info		Aminosalicylic acid		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Vitamins				Aminosalicylates
Structure

Mechanism of Cyanocobalamin-Aminosalicylic acid Interaction (Severity Level: Minor)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Cyanocobalamin				Aminosalicylic acid
Mechanism		Vitamin B12				Decrease the absorption of vitamin B12
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Cyanocobalamin caused by Aminosalicylic acid

References
1	Halsted CH, McIntyre PA "Intestinal malabsorption caused by aminosalicylic acid therapy." Arch Intern Med 130 (1972): 935-9. [PMID: 5082475]
2	Heinivaara O "Malabsorption of vitamin B112 during treatment with para-aminosalicylic acid: a preliminary report." Acta Med Scand 175 (1964): 469-71. [PMID: 14149652]
3	Levine RA, "Steatorrhea induced by para-aminosalicylic acid." Ann Intern Med 68 (1968): 1265. [PMID: 4871323]
4	Palva IP, Rytkonen U, Slatulkkila M, Palva M "Drug-induced malabsorption of vitamin B12." Scand J Haematol 9 (1972): 5-7. [PMID: 5056480]
5	Product Information. Paser Granules (aminosalicylic acid). Jacobus Pharmaceutical Company, Princeton, NJ.