Details of Drug

Drug General Information (ID: D1817)
Drug Name	Indium In-111 oxyquinoline
Drug Type	Small molecule
Drug Synonymous	indium 8-quinolinolate\|AKOS002375061\|Q27282981 Click to Show/Hide
Therapeutic Class	Diagnostic Radiopharmaceuticals
Structure
Structure	3D Structure		2D Structure
Formula	C27H18InN3O3
InChI	InChI=1S/3C9H7NO.In/c311-8-5-1-3-7-4-2-6-10-9(7)8;/h31-6,11H;/q;;;+3/p-3
InChIKey	AEGSYIKLTCZUEZ-UHFFFAOYSA-K
Canonical SMILES	C1=CC2=C(C(=C1)O[In](OC3=CC=CC4=C3N=CC=C4)OC5=CC=CC6=C5N=CC=C6)N=CC=C2
External Link
	Pubchem ID	16685037
	CAS Number	CAS 65389-08-4
	TTD ID	D02JYY

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM003 Affected organization distribution AM007 Pharmacodynamic antagonistic effects BM014 Interference of cell/tissue uptake BM107 Attenuated pharmacological effects (Unspecific)
Relation Graph

Full list of drugs interacting with Indium In-111 oxyquinoline
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 133
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0030		Aldesleukin	NA	NA	Moderate		Inter Info	[1]
D0056		Amikacin	C22H43N5O13	37768	Moderate		Inter Info	[1]
D0057		Amikacin (liposome)	C22H43N5O13	37768	Moderate		Inter Info	[1]
D0065		Aminosalicylic acid	C7H7NO3	4649	Moderate		Inter Info	[1]
D0073		Amoxicillin	C16H19N3O5S	33613	Moderate		Inter Info	[1]
D0079		Ampicillin	C16H19N3O4S	6249	Moderate		Inter Info	[1]
D0139		Azithromycin	C38H72N2O12	447043	Moderate		Inter Info	[1]
D0140		Aztreonam	C13H17N5O8S2	5742832	Moderate		Inter Info	[1]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[1]
D0142		Bacitracin	C66H103N17O16S	10909430	Moderate		Inter Info	[1]
D0148		Beclomethasone dipropionate	C28H37ClO7	21700	Moderate		Inter Info	[1]
D0167		Benzylpenicillin	C16H18N2O4S	5904	Moderate		Inter Info	[1]
D0168		Benzylpenicillin (potassium)	C16H18N2O4S	5904	Moderate		Inter Info	[1]
D0169		Benzylpenicillin (sodium)	C16H18N2O4S	5904	Moderate		Inter Info	[1]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[1]
D0215		Budesonide	C25H34O6	5281004	Moderate		Inter Info	[1]
D0252		Capreomycin	C50H88N28O15	3000502	Moderate		Inter Info	[1]
D0257		Carbenicillin	C17H18N2O6S	20824	Moderate		Inter Info	[1]
D0271		Cefaclor	C15H14ClN3O4S	51039	Moderate		Inter Info	[1]
D0272		Cefadroxil	C16H17N3O5S	47965	Moderate		Inter Info	[1]
D0273		Cefalotin	C16H16N2O6S2	6024	Moderate		Inter Info	[1]
D0274		Cefamandole	C18H18N6O5S2	456255	Moderate		Inter Info	[1]
D0275		Cefapirin	C17H17N3O6S2	30699	Moderate		Inter Info	[1]
D0276		Cefazolin	C14H14N8O4S3	33255	Moderate		Inter Info	[1]
D0277		Cefdinir	C14H13N5O5S2	6915944	Moderate		Inter Info	[1]
D0278		Cefditoren	C19H18N6O5S3	9870843	Moderate		Inter Info	[1]
D0279		Cefepime	C19H24N6O5S2	5479537	Moderate		Inter Info	[1]
D0281		Cefixime	C16H15N5O7S2	5362065	Moderate		Inter Info	[1]
D0282		Cefmetazole	C15H17N7O5S3	42008	Moderate		Inter Info	[1]
D0283		Cefonicid	C18H18N6O8S3	43594	Moderate		Inter Info	[1]
D0284		Cefoperazone	C25H27N9O8S2	44187	Moderate		Inter Info	[1]
D0285		Cefotaxime	C16H17N5O7S2	5742673	Moderate		Inter Info	[1]
D0286		Cefotetan	C17H17N7O8S4	53025	Moderate		Inter Info	[1]
D0287		Cefoxitin	C16H17N3O7S2	441199	Moderate		Inter Info	[1]
D0288		Cefpodoxime	C15H17N5O6S2	6335986	Moderate		Inter Info	[1]
D0289		Cefprozil	C18H19N3O5S	5281006	Moderate		Inter Info	[1]
D0290		Cefradine	C16H19N3O4S	38103	Moderate		Inter Info	[1]
D0291		Ceftaroline fosamil	C22H21N8O8PS4	9852981	Moderate		Inter Info	[1]
D0292		Ceftazidime	C22H22N6O7S2	5481173	Moderate		Inter Info	[1]
D0293		Ceftibuten	C15H14N4O6S2	5282242	Moderate		Inter Info	[1]
D0294		Ceftizoxime	C13H13N5O5S2	6533629	Moderate		Inter Info	[1]
D0295		Ceftolozane	C23H30N12O8S2	53234134	Moderate		Inter Info	[1]
D0296		Ceftriaxone	C18H18N8O7S3	5479530	Moderate		Inter Info	[1]
D0297		Cefuroxime	C16H16N4O8S	5479529	Moderate		Inter Info	[1]
D0301		Cephalexin	C16H17N3O4S	27447	Moderate		Inter Info	[1]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[1]
D0333		Ciclesonide	C32H44O7	6918155	Moderate		Inter Info	[1]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[1]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[1]
D0349		Clarithromycin	C38H69NO13	84029	Moderate		Inter Info	[1]
D0354		Clindamycin	C18H33ClN2O5S	446598	Moderate		Inter Info	[1]
D0358		Clofazimine	C27H22Cl2N4	2794	Moderate		Inter Info	[1]
D0369		Cloxacillin	C19H18ClN3O5S	6098	Moderate		Inter Info	[1]
D0383		Colistimethate	C58H105N16O28S5-5	70789202	Moderate		Inter Info	[1]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[1]
D0401		Cycloserine	C3H6N2O2	6234	Moderate		Inter Info	[1]
D0413		Dalfopristin	C34H50N4O9S	6323289	Moderate		Inter Info	[1]
D0419		Dapsone	C12H12N2O2S	2955	Moderate		Inter Info	[1]
D0421		Daptomycin	C72H101N17O26	16134395	Moderate		Inter Info	[1]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[1]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[1]
D0480		Dicloxacillin	C19H17Cl2N3O5S	18381	Moderate		Inter Info	[1]
D0519		Doripenem	C15H24N4O6S2	73303	Moderate		Inter Info	[1]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[1]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[1]
D0596		Ertapenem	C22H25N3O7S	150610	Moderate		Inter Info	[1]
D0597		Erythromycin	C37H67NO13	12560	Moderate		Inter Info	[1]
D0616		Ethambutol	C10H24N2O2	14052	Moderate		Inter Info	[1]
D1731		Ethionamide	C8H10N2S	2761171	Moderate		Inter Info	[1]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[1]
D0672		Flunisolide	C24H31FO6	82153	Moderate		Inter Info	[1]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[1]
D0718		Gentamicin	C21H43N5O7	3467	Moderate		Inter Info	[1]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[1]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[1]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[1]
D0876		Kanamycin	C18H36N4O11	6032	Moderate		Inter Info	[1]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[1]
D0927		Lidocaine	C14H22N2O	3676	Moderate		Inter Info	[1]
D0931		Lincomycin	C18H34N2O6S	3000540	Moderate		Inter Info	[1]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[1]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[1]
D0949		Loracarbef	C16H16ClN3O4	5284585	Moderate		Inter Info	[1]
D1008		Meropenem	C17H25N3O5S	441130	Moderate		Inter Info	[1]
D1020		Methenamine	C6H12N4	4101	Moderate		Inter Info	[1]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[1]
D1044		Meticillin	C17H20N2O6S	6087	Moderate		Inter Info	[1]
D1051		Metronidazole	C6H9N3O3	4173	Moderate		Inter Info	[1]
D1055		Mezlocillin	C21H25N5O8S2	656511	Moderate		Inter Info	[1]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[1]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[1]
D1099		Nafcillin	C21H22N2O5S	8982	Moderate		Inter Info	[1]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[1]
D1120		Neomycin	C23H46N6O13	8378	Moderate		Inter Info	[1]
D1126		Netilmicin	C21H41N5O7	441306	Moderate		Inter Info	[1]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Moderate		Inter Info	[1]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[1]
D1159		Novobiocin	C31H36N2O11	54675769	Moderate		Inter Info	[1]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[1]
D1192		Oxacillin	C19H19N3O5S	6196	Moderate		Inter Info	[1]
D1209		Oxytetracycline	C22H24N2O9	54675779	Moderate		Inter Info	[1]
D1228		Paromomycin	C23H45N5O14	165580	Moderate		Inter Info	[1]
D1268		Phenoxymethylpenicillin	C16H18N2O5S	6869	Moderate		Inter Info	[1]
D1296		Piperacillin	C23H27N5O7S	43672	Moderate		Inter Info	[1]
D1310		Polymyxin B	C56H98N16O13	49800004	Moderate		Inter Info	[1]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[1]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[1]
D1343		Procainamide	C13H21N3O	4913	Moderate		Inter Info	[1]
D1364		Pyrazinamide	C5H5N3O	1046	Moderate		Inter Info	[1]
D1399		Rifabutin	C46H62N4O11	135398743	Moderate		Inter Info	[1]
D1400		Rifampicin	C43H58N4O12	135398735	Moderate		Inter Info	[1]
D1401		Rifapentine	C47H64N4O12	135403821	Moderate		Inter Info	[1]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[1]
D1500		Spectinomycin	C14H24N2O7	15541	Moderate		Inter Info	[1]
D1507		Streptomycin	C21H39N7O12	19649	Moderate		Inter Info	[1]
D1513		Sulfadiazine	C10H10N4O2S	5215	Moderate		Inter Info	[1]
D1514		Sulfadoxine	C12H14N4O4S	17134	Moderate		Inter Info	[1]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Moderate		Inter Info	[1]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Moderate		Inter Info	[1]
D1517		Sulfasalazine	C18H14N4O5S	5339	Moderate		Inter Info	[1]
D1519		Sulfisoxazole	C11H13N3O3S	5344	Moderate		Inter Info	[1]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[1]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[1]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[1]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[1]
D1580		Ticarcillin	C15H16N2O6S2	36921	Moderate		Inter Info	[1]
D1582		Tigecycline	C29H39N5O8	54686904	Moderate		Inter Info	[1]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[1]
D1597		Tobramycin	C18H37N5O9	36294	Moderate		Inter Info	[1]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[1]
D1645		Trimethoprim	C14H18N4O3	5578	Moderate		Inter Info	[1]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[1]
D1680		Vancomycin	C66H75Cl2N9O24	14969	Moderate		Inter Info	[1]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 9
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0162		Benznidazole	C12H12N4O3	31593	Moderate		Inter Info	[1]
D0280		Cefiderocol	C30H34ClN7O10S2	77843966	Moderate		Inter Info	[1]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[1]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Moderate		Inter Info	[1]
D0589		Eravacycline	C27H31FN4O8	54726192	Moderate		Inter Info	[1]
D0683		Fluticasone	C22H27F3O4S	5311101	Moderate		Inter Info	[1]
D1304		Plazomicin	C25H48N6O10	42613186	Moderate		Inter Info	[1]
D1452		Secnidazole	C7H11N3O3	71815	Moderate		Inter Info	[1]
D1653		Troleandomycin	C41H67NO15	202225	Moderate		Inter Info	[1]

References
1	Product Information. Indium Oxyquinoline In-111 (indium oxyquinoline In-111). GE Healthcare, Princeton, NJ.

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