Details of Drug

Drug General Information (ID: D1488)
Drug Name	Sodium sulfate
Drug Type	Small molecule
Drug Synonymous	SODIUM SULFATE; 7757-82-6; Disodium sulfate; Sodium sulfate, anhydrous; Sodium sulphate; Salt cake; Sodium sulfate anhydrous; Sulfuric acid disodium salt; sodiumsulfate; disodium;sulfate; Disodium sulphate; Sulfuric acid, sodium salt; Sulfate, sodium; 15124-09-1; Sodium sulfate anyhdrous; Sodium sulphate anhydrous; Sulfuric acid sodium salt (1:2); UNII-36KCS0R750; Na2SO4; MFCD00003504; Sodium sulfate, dried [JAN]; CHEBI:32149; 36KCS0R750; Sodium sulfate, dried (JAN); Dibasic sodium sulfate; Natriumsulfat (German); Na sulphate; Caswell No. 793; HSDB 5042; Sodium sulfate (solution); Thenardite (Na2(SO4)); Mirabilite; Natriumsulfat; Sodium tallow alcohol sulfate; Glaubers salt; EINECS 231-820-9; EINECS 268-366-6; EINECS 268-773-9; EINECS 270-211-2; EPA Pesticide Chemical Code 005604; NSC 403914; Sulfuric acid, mono-C14-18-alkyl esters, sodium salts; Sodium Sulfate ACS HE; AI3-02398; Na2O4S; SDA 17-062-04; Sulfuric acid sodium salt; DSSTox_CID_1291; Sodium sulphate, anhydrous; EC 231-820-9; DSSTox_RID_76063; DSSTox_GSID_21291; Sodium sulfate, ACS reagent; Sodium sulfate, dried (TN); CHEMBL233406; INS NO.514(II); DTXSID1021291; INS NO.514(I); Anhydous sodium sulfate (JP17); INS-514(II); Sodium Sulfate - Drilling Grade; INS-514(I); 7757-82-6 (anhyd.); BCP13313; Sodium sulfate, for residue analysis; Tox21_201045; E-514(II); AKOS015833463; Sodium Sulfate Anhydrous Granular ACS; Sodium sulfate, BioXtra, >=99.0%; Sulfuric acid disodium salt, anhydrous; DB09472; NCGC00258598-01; Sodium sulfate, LR, anhydrous, >=99%; 13759-07-4; E-514(I); E514; K354; Sodium Sulfate Anhydrous; Sodium sulphate; CAS-7757-82-6; Sodium sulfate, AR, anhydrous, >=99.5%; FT-0645112; S0566; Sodium sulfate, 99.9955% (metals basis); Sodium sulfate, ReagentPlus(R), >=99.0%; Sodium sulfate, for pesticide residue analysis; Sodium sulfate, Trace metals grade, 99.99%; D01732; Sodium sulfate, >=99.99% trace metals basis; Sodium sulfate, JIS special grade, >=99.0%; Sodium sulfate, Vetec(TM) reagent grade, 99%; Sodium sulfate, meets USP testing specifications; Q211737; Sodium sulfate, for HPLC, 99.0-101.0% (T); Sodium sulfate, purum, anhydrous, >=99.0% (T); Sodium sulfate, SAJ first grade, >=99.0%, beads; Sodium sulfate, SAJ first grade, >=99.0%, powder; Sodium sulfate, >=99.0%, plant cell culture tested; Sodium sulfate, BioUltra, anhydrous, >=99.0% (T); Sodium sulfate, p.a., 99.0-101.0%, reag. ISO; Sodium sulfate, for pesticide residue analysis, 99.0%; Sodium sulfate, tested according to Ph.Eur., anhydrous; Sodium sulfate, ACS reagent, >=99.0%, anhydrous, powder; Sodium sulfate, ACS reagent, >=99.0%, anhydrous, granular; Sodium sulfate, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%; Sodium sulfate anhydrous, United States Pharmacopeia (USP) Reference Standard; Sodium sulfate, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), >=99%; Sodium sulfate, anhydrous, granular, free-flowing, Redi-Dri(TM), ACS reagent, >=99%; Sodium sulfate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., anhydrous, >=99.0%; Sodium sulfate, puriss., meets analytical specification of Ph. Eur., BP, USP, anhydrous, 99.0-100.5% (calc. to the dried substance) Click to Show/Hide
Therapeutic Class	Laxatives
Structure
Structure	3D Structure		2D Structure
Formula	Na2O4S
InChI	InChI=1S/2Na.H2O4S/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2
InChIKey	PMZURENOXWZQFD-UHFFFAOYSA-L
Canonical SMILES	[O-]S(=O)(=O)[O-].[Na+].[Na+]
External Link
External Link	Pubchem ID	24436

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM006 Pharmacodynamic additive effects BM003 Complex formation BM054 Increased risk of GI mucosal injury/bleeding risk BM069 Increased risk of lowers seizure threshold BM081 Increased risk of ventricular arrhythmias BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Sodium sulfate
Affected gastrointestinal absorption
	Complex formation					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0490		Digitoxin	C41H64O13	441207	Minor		Inter Info	[12], [13], [3]
D0491		Digoxin	C41H64O14	2724385	Minor		Inter Info	[12], [13], [3]
Pharmacodynamic additive effects
	Increased risk of GI mucosal injury/bleeding risk					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1266		Phenolphthalein	C20H14O4	4764	Moderate		Inter Info	[3], [10], [11]
D0269		Castor oil	C57H104O9	14030006	Moderate		Inter Info	[3], [10], [11]
D0701		Frangula purshiana bark	NA	NA	Moderate		Inter Info	[3], [10], [11]
	Increased risk of lowers seizure threshold					Drug Num: 98
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0035		Alfentanil	C21H32N6O3	51263	Moderate		Inter Info	[3], [6], [4]
D0051		Amantadine	C10H17N	2130	Moderate		Inter Info	[3], [6], [4]
D0064		Aminophylline	C16H24N10O4	9433	Moderate		Inter Info	[3], [6], [4]
D0074		Amphetamine	C9H13N	3007	Moderate		Inter Info	[3], [6], [4]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[3], [6], [4]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[3], [6], [4]
D0175		Bethanechol	C7H17N2O2+	2370	Moderate		Inter Info	[3], [6], [4]
D0191		Blinatumomab	NA	NA	Moderate		Inter Info	[3], [4], [6]
D0202		Brexpiprazole	C25H27N3O2S	11978813	Moderate		Inter Info	[3], [6], [4]
D0220		Bupropion	C13H18ClNO	444	Moderate		Inter Info	[3], [6], [4]
D0226		Butorphanol	C21H29NO2	5361092	Moderate		Inter Info	[3], [6], [4]
D0262		Cariprazine	C21H32Cl2N4O	11154555	Moderate		Inter Info	[3], [6], [4]
D0377		Cocaine (nasal)	C17H21NO4	446220	Moderate		Inter Info	[3], [6], [4]
D0379		Codeine	C18H21NO3	5284371	Moderate		Inter Info	[3], [6], [4]
D0398		Cyclobenzaprine	C20H21N	2895	Moderate		Inter Info	[3], [6], [4]
D0401		Cycloserine	C3H6N2O2	6234	Moderate		Inter Info	[3], [6], [4]
D0412		Dalfampridine	C5H6N2	1727	Moderate		Inter Info	[3], [6], [4]
D0451		Desvenlafaxine	C16H25NO2	125017	Moderate		Inter Info	[3], [6], [4]
D0457		Dexfenfluramine	C12H16F3N	66265	Moderate		Inter Info	[3], [6], [4]
D0460		Dexmethylphenidate	C14H19NO2	154101	Moderate		Inter Info	[3], [6], [4]
D0465		Dextroamphetamine	C9H13N	5826	Moderate		Inter Info	[3], [6], [4]
D0470		Dezocine	C16H23NO	3033053	Moderate		Inter Info	[3], [4], [6]
D0471		Diamorphine	C21H23NO5	5462328	Moderate		Inter Info	[3], [6], [4]
D0486		Diethylpropion	C13H19NO	7029	Moderate		Inter Info	[3], [6], [4]
D0523		Doxapram	C24H30N2O2	3156	Moderate		Inter Info	[3], [4], [6]
D0533		Dronabinol	C21H30O2	16078	Moderate		Inter Info	[3], [6], [4]
D0596		Ertapenem	C22H25N3O7S	150610	Moderate		Inter Info	[3], [6], [4]
D0641		Fenfluramine	C12H16F3N	3337	Moderate		Inter Info	[3], [6], [4]
D0646		Fentanyl	C22H28N2O	3345	Moderate		Inter Info	[3], [6], [4]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[3], [6], [4]
D0707		Galantamine	C17H21NO3	9651	Moderate		Inter Info	[3], [6], [4]
D0772		Hydrocodone	C18H21NO3	5284569	Moderate		Inter Info	[3], [6], [4]
D0776		Hydromorphone	C17H19NO3	5284570	Moderate		Inter Info	[3], [6], [4]
D0821		Interferon alfa-2a, Recombinant	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0822		Interferon alfa-2b	C16H17Cl3I2N3NaO5S	71306834	Moderate		Inter Info	[3], [6], [4]
D0824		Interferon alfa-n1	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0825		Interferon alfa-n3	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0823		Interferon alfacon-1	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0826		Interferon beta-1a	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0827		Interferon beta-1b	NA	NA	Moderate		Inter Info	[3], [4], [6]
D0828		Interferon gamma-1b	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0853		Isocarboxazid	C12H13N3O2	3759	Moderate		Inter Info	[3], [6], [4]
D0920		Levomilnacipran	C15H22N2O	6917779	Moderate		Inter Info	[3], [6], [4]
D0923		Levorphanol	C17H23NO	5359272	Moderate		Inter Info	[3], [6], [4]
D0927		Lidocaine	C14H22N2O	3676	Moderate		Inter Info	[3], [6], [4]
D0932		Lindane	C6H6Cl6	727	Moderate		Inter Info	[3], [6], [4]
D0957		Loxapine	C18H18ClN3O	3964	Moderate		Inter Info	[3], [6], [4]
D0959		Lumateperone	C24H28FN3O	21302490	Moderate		Inter Info	[3], [6], [4]
D0961		Lurasidone	C28H36N4O2S	213046	Moderate		Inter Info	[3], [6], [4]
D0981		Mazindol	C16H13ClN2O	4020	Moderate		Inter Info	[3], [6], [4]
D1008		Meropenem	C17H25N3O5S	441130	Moderate		Inter Info	[3], [4], [6]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[3], [6], [4]
D1019		Methdilazine	C18H20N2S	14677	Moderate		Inter Info	[3], [6], [4]
D1039		Methylphenidate	C14H19NO2	4158	Moderate		Inter Info	[3], [6], [4]
D1046		Metoclopramide	C14H22ClN3O2	4168	Moderate		Inter Info	[3], [6], [4]
D1066		Milnacipran	C15H22N2O	65833	Moderate		Inter Info	[3], [6], [4]
D1084		Molindone	C16H24N2O2	23897	Moderate		Inter Info	[3], [6], [4]
D1089		Morphine	C17H19NO3	5288826	Moderate		Inter Info	[3], [6], [4]
D1090		Morphine (liposomal)	C17H19NO3	5288826	Moderate		Inter Info	[3], [4], [6]
D1093		Muromonab	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1100		Nalbuphine	C21H27NO4	5311304	Moderate		Inter Info	[3], [6], [4]
D1117		Nefazodone	C25H32ClN5O2	4449	Moderate		Inter Info	[3], [6], [4]
D1118		Nelarabine	C11H15N5O5	3011155	Moderate		Inter Info	[3], [6], [4]
D1122		Neostigmine	C12H19N2O2+	4456	Moderate		Inter Info	[3], [6], [4]
D1194		Oxamniquine	C14H21N3O3	4612	Moderate		Inter Info	[3], [6], [4]
D1201		Oxtriphylline	C12H21N5O3	656652	Moderate		Inter Info	[3], [6], [4]
D1203		Oxycodone	C18H21NO4	5284603	Moderate		Inter Info	[3], [6], [4]
D1229		Paroxetine	C19H20FNO3	43815	Moderate		Inter Info	[3], [6], [4]
D1237		Peginterferon alfa-2a	NA	NA	Moderate		Inter Info	[3], [4], [6]
D1238		Peginterferon alfa-2b	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1239		Peginterferon beta-1a	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1243		Pemoline	C9H8N2O2	4723	Moderate		Inter Info	[3], [6], [4]
D1247		Pentazocine	C19H27NO	441278	Moderate		Inter Info	[3], [6], [4]
D1262		Phendimetrazine	C12H17NO	30487	Moderate		Inter Info	[3], [4], [6]
D1263		Phenelzine	C8H12N2	3675	Moderate		Inter Info	[3], [6], [4]
D1270		Phentermine	C10H15N	4771	Moderate		Inter Info	[3], [6], [4]
D1281		Phenylpropanolamine	C9H13NO	26934	Moderate		Inter Info	[3], [6], [4]
D1285		Physostigmine	C15H21N3O2	5983	Moderate		Inter Info	[3], [6], [4]
D1297		Piperazine	C4H10N2	4837	Moderate		Inter Info	[3], [6], [4]
D1355		Propiomazine	C20H24N2OS	4940	Moderate		Inter Info	[3], [6], [4]
D1390		Remifentanil	C20H28N2O5	60815	Moderate		Inter Info	[3], [6], [4]
D1406		Rimantadine	C12H21N	5071	Moderate		Inter Info	[3], [6], [4]
D1418		Rivastigmine	C14H22N2O2	77991	Moderate		Inter Info	[3], [6], [4]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[3], [6], [4]
D0054		Amifampridine	C5H7N3	5918	Moderate		Inter Info	[3], [6], [4]
D0280		Cefiderocol	C30H34ClN7O10S2	77843966	Moderate		Inter Info	[3], [6], [4]
D0940		Lithium carbonate	CLi2O3	11125	Moderate		Inter Info	[7], [3], [6]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[7], [3], [6]
D1183		Opium	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1512		Sufentanil	C22H30N2O2S	41693	Moderate		Inter Info	[3], [6], [4]
D1525		Tacrine	C13H14N2	1935	Moderate		Inter Info	[3], [6], [4]
D1535		Tapentadol	C14H23NO	9838022	Moderate		Inter Info	[3], [4], [6]
D1570		Theophylline	C7H8N4O2	2153	Moderate		Inter Info	[3], [6], [4]
D1572		Thiethylperazine	C22H29N3S2	5440	Moderate		Inter Info	[3], [4], [6]
D1576		Thiothixene	C23H29N3O2S2	941651	Moderate		Inter Info	[3], [6], [4]
D1620		Tranylcypromine	C9H11N	19493	Moderate		Inter Info	[3], [6], [4]
D1696		Vilazodone	C26H27N5O2	6918314	Moderate		Inter Info	[3], [6], [4]
D1708		Vortioxetine	C18H22N2S	9966051	Moderate		Inter Info	[3], [6], [4]
	Increased risk of ventricular arrhythmias					Drug Num: 156
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0066		Amiodarone	C25H29I2NO3	2157	Major		Inter Info	[1], [2], [3]
D0107		Arsenic trioxide	As2O3	14888	Major		Inter Info	[1], [2], [3]
D0115		Astemizole	C28H31FN4O	2247	Major		Inter Info	[1], [2], [3]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Major		Inter Info	[1], [2], [3]
D0170		Bepridil	C24H34N2O	2351	Major		Inter Info	[1], [2], [3]
D0342		Cisapride	C23H29ClFN3O4	6917698	Major		Inter Info	[1], [2], [3]
D0370		Clozapine	C18H19ClN4	135398737	Major		Inter Info	[1], [2], [3]
D0508		Disopyramide	C21H29N3O	3114	Major		Inter Info	[1], [2], [3]
D0513		Dofetilide	C19H27N3O5S2	71329	Major		Inter Info	[1], [2], [3]
D0514		Dolasetron	C19H20N2O3	3033818	Major		Inter Info	[1], [2], [3]
D0534		Dronedarone	C31H44N2O5S	208898	Major		Inter Info	[1], [2], [3]
D0535		Droperidol	C22H22FN3O2	3168	Major		Inter Info	[1], [2], [3]
D0740		Grepafloxacin	C19H22FN3O3	72474	Major		Inter Info	[1], [2], [3]
D0787		Ibutilide	C20H36N2O3S	60753	Major		Inter Info	[1], [2], [3]
D0909		Levacetylmethadol	C23H31NO2	15130	Major		Inter Info	[1], [2], [3]
D1010		Mesoridazine	C21H26N2OS2	4078	Major		Inter Info	[1], [2], [3]
D1017		Methadone	C21H27NO	4095	Major		Inter Info	[1], [2], [3]
D1136		Nilotinib	C28H22F3N7O	644241	Major		Inter Info	[1], [2], [3]
D1221		Panobinostat	C21H23N3O2	6918837	Major		Inter Info	[1], [2], [3]
D1292		Pimozide	C28H29F2N3O	16362	Major		Inter Info	[1], [2], [3]
D1343		Procainamide	C13H21N3O	4913	Major		Inter Info	[1], [2], [3]
D1371		Quinidine	C20H24N2O2	441074	Major		Inter Info	[1], [2], [3]
D1372		Quinine	C20H24N2O2	3034034	Major		Inter Info	[1], [2], [3]
D1444		Saquinavir	C38H50N6O5	441243	Major		Inter Info	[1], [2], [3]
D1498		Sotalol	C12H20N2O3S	5253	Major		Inter Info	[1], [2], [3]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Major		Inter Info	[1], [2], [3]
D1555		Terfenadine	C32H41NO2	5405	Major		Inter Info	[1], [2], [3]
D1612		Toremifene	C26H28ClNO	3005573	Major		Inter Info	[1], [2], [3]
D1681		Vandetanib	C22H24BrFN4O2	3081361	Major		Inter Info	[1], [2], [3]
D1726		Ziprasidone	C21H21ClN4OS	60854	Major		Inter Info	[1], [2], [3]
D0003		Abarelix	C72H95ClN14O14	16131215	Moderate		Inter Info	[4], [2], [3]
D0007		Abiraterone	C24H31NO	132971	Moderate		Inter Info	[4], [2], [3]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[4], [2], [3]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[7], [3], [6]
D0067		Amisulpride	C17H27N3O4S	2159	Moderate		Inter Info	[7], [3], [6]
D0068		Amitriptyline	C20H23N	2160	Moderate		Inter Info	[7], [3], [6]
D0072		Amoxapine	C17H16ClN3O	2170	Moderate		Inter Info	[7], [3], [6]
D0084		Anagrelide	C10H7Cl2N3O	135409400	Moderate		Inter Info	[4], [2], [3]
D0097		Apomorphine	C17H17NO2	6005	Moderate		Inter Info	[4], [2], [3]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[7], [3], [6]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[7], [3], [6]
D0139		Azithromycin	C38H72N2O12	447043	Moderate		Inter Info	[4], [2], [3]
D0180		Bicalutamide	C18H14F4N2O4S	2375	Moderate		Inter Info	[4], [2], [3]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[4], [2], [3]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[7], [3], [6]
D0230		Cabozantinib	C28H24FN3O5	25102847	Moderate		Inter Info	[4], [2], [3]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[4], [2], [3]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[7], [3], [6]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[8], [9], [3]
D0336		Cilostazol	C20H27N5O2	2754	Moderate		Inter Info	[4], [2], [3]
D0349		Clarithromycin	C38H69NO13	84029	Moderate		Inter Info	[4], [2], [3]
D0358		Clofazimine	C27H22Cl2N4	2794	Moderate		Inter Info	[4], [2], [3]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[7], [3], [6]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[4], [2], [3]
D0429		Daunorubicin	C27H29NO10	30323	Moderate		Inter Info	[4], [2], [3]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Moderate		Inter Info	[4], [2], [3]
D0437		Degarelix	C82H103ClN18O16	16136245	Moderate		Inter Info	[4], [2], [3]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[7], [3], [6]
D0525		Doxepin	C19H21NO	667477	Moderate		Inter Info	[7], [3], [6]
D0526		Doxepin (topical)	C19H21NO	667477	Moderate		Inter Info	[7], [3], [6]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[4], [2], [3]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[4], [2], [3]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[7], [3], [6]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[4], [2], [3]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[4], [2], [3]
D0597		Erythromycin	C37H67NO13	12560	Moderate		Inter Info	[4], [2], [3]
D0599		Escitalopram	C20H21FN2O	146570	Moderate		Inter Info	[7], [3], [6]
D0632		Ezogabine	C16H18FN3O2	121892	Moderate		Inter Info	[4], [2], [3]
D0664		Flecainide	C17H20F6N2O3	3356	Moderate		Inter Info	[4], [2], [3]
D0667		Fluconazole	C13H12F2N6O	3365	Moderate		Inter Info	[4], [2], [3]
D0676		Fluoxetine	C17H18F3NO	3386	Moderate		Inter Info	[7], [3], [6]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[7], [3], [6]
D0682		Flutamide	C11H11F3N2O3	3397	Moderate		Inter Info	[4], [2], [3]
D0694		Foscarnet	CH3O5P	3415	Moderate		Inter Info	[7], [3], [6]
D0737		Goserelin	C59H84N18O14	5311128	Moderate		Inter Info	[4], [2], [3]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[4], [2], [3]
D0750		Haloperidol	C21H23ClFNO2	3559	Moderate		Inter Info	[7], [3], [6]
D0751		Halothane	C2HBrClF3	3562	Moderate		Inter Info	[4], [2], [3]
D0758		Histrelin	C66H86N18O12	25077993	Moderate		Inter Info	[4], [2], [3]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[7], [3], [6]
D0781		Hydroxyzine	C21H27ClN2O2	3658	Moderate		Inter Info	[4], [2], [3]
D0788		Idarubicin	C26H27NO9	42890	Moderate		Inter Info	[4], [2], [3]
D0791		Iloperidone	C24H27FN2O4	71360	Moderate		Inter Info	[7], [3], [6]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[7], [3], [6]
D0806		Inotuzumab ozogamicin	NA	NA	Moderate		Inter Info	[4], [2], [3]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Moderate		Inter Info	[4], [2], [3]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[4], [2], [3]
D0903		Lenvatinib	C21H19ClN4O4	9823820	Moderate		Inter Info	[4], [2], [3]
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[7], [3], [6]
D0942		Lofexidine	C11H12Cl2N2O	30668	Moderate		Inter Info	[4], [2], [3]
D0979		Maprotiline	C20H23N	4011	Moderate		Inter Info	[7], [3], [6]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[7], [3], [6]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[7], [3], [6]
D1063		Mifepristone	C29H35NO2	55245	Moderate		Inter Info	[4], [2], [3]
D1075		Mirtazapine	C17H19N3	4205	Moderate		Inter Info	[7], [3], [6]
D1137		Nilutamide	C12H10F3N3O4	4493	Moderate		Inter Info	[4], [2], [3]
D1181		Ondansetron	C18H19N3O	4595	Moderate		Inter Info	[4], [2], [3]
D1190		Osimertinib	C28H33N7O2	71496458	Moderate		Inter Info	[4], [2], [3]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[4], [2], [3]
D1210		Oxytocin	C43H66N12O12S2	439302	Moderate		Inter Info	[4], [2], [3]
D1215		Paliperidone	C23H27FN4O3	115237	Moderate		Inter Info	[7], [3], [6]
D1216		Palonosetron	C19H24N2O	6337614	Moderate		Inter Info	[4], [2], [3]
D1230		Pasireotide	C58H66N10O9	9941444	Moderate		Inter Info	[4], [2], [3]
D1246		Pentamidine	C19H24N4O2	4735	Moderate		Inter Info	[4], [2], [3]
D1254		Perflutren	C3F8	6432	Moderate		Inter Info	[4], [2], [3]
D1290		Pimavanserin	C25H34FN3O2	10071196	Moderate		Inter Info	[4], [2], [3]
D1315		Posaconazole	C37H42F2N8O4	468595	Moderate		Inter Info	[4], [2], [3]
D1339		Primaquine	C15H21N3O	4908	Moderate		Inter Info	[4], [2], [3]
D1342		Probucol	C31H48O2S2	4912	Moderate		Inter Info	[4], [2], [3]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[7], [3], [6]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[7], [3], [6]
D1353		Propafenone	C21H27NO3	4932	Moderate		Inter Info	[4], [2], [3]
D1356		Propofol	C12H18O	4943	Moderate		Inter Info	[4], [2], [3]
D1361		Protriptyline	C19H21N	4976	Moderate		Inter Info	[7], [3], [6]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[7], [3], [6]
D1383		Ranolazine	C24H33N3O4	56959	Moderate		Inter Info	[4], [2], [3]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[4], [2], [3]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[7], [3], [6]
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[4], [2], [3]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[4], [2], [3]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[7], [3], [6]
D1463		Sevoflurane	C4H3F7O	5206	Moderate		Inter Info	[4], [2], [3]
D0452		Deutetrabenazine	C19H27NO3	73437646	Moderate		Inter Info	[4], [2], [3]
D0569		Encorafenib	C22H27ClFN7O4S	50922675	Moderate		Inter Info	[4], [2], [3]
D0577		Entrectinib	C31H34F2N6O2	25141092	Moderate		Inter Info	[4], [2], [3]
D0700		Fostemsavir	C25H26N7O8P	11319217	Moderate		Inter Info	[4], [2], [3]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[4], [2], [3]
D0872		Ivosidenib	C28H22ClF3N6O3	71657455	Moderate		Inter Info	[4], [2], [3]
D0899		Lefamulin	C28H45NO5S	25185057	Moderate		Inter Info	[4], [2], [3]
D0965		Macimorelin	C26H30N6O3	9804938	Moderate		Inter Info	[4], [2], [3]
D1189		Osilodrostat	C13H10FN3	44139752	Moderate		Inter Info	[4], [2], [3]
D1211		Ozanimod	C23H24N4O3	52938427	Moderate		Inter Info	[4], [2], [3]
D1302		Pitolisant	C17H26ClNO	9948102	Moderate		Inter Info	[4], [2], [3]
D1398		Ribociclib	C23H30N8O	44631912	Moderate		Inter Info	[4], [2], [3]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[4], [2], [3]
D1459		Selpercatinib	C29H31N7O3	134436906	Moderate		Inter Info	[4], [2], [3]
D1474		Siponimod	C29H35F3N2O3	44599207	Moderate		Inter Info	[4], [2], [3]
D1634		Triclabendazole	C14H9Cl3N2OS	50248	Moderate		Inter Info	[4], [2], [3]
D1673		Valbenazine	C24H38N2O4	24795069	Moderate		Inter Info	[4], [2], [3]
D1491		Solifenacin	C23H26N2O2	154059	Moderate		Inter Info	[4], [2], [3]
D1497		Sorafenib	C21H16ClF3N4O3	216239	Moderate		Inter Info	[4], [2], [3]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[4], [2], [3]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[4], [2], [3]
D1542		Telavancin	C80H106Cl2N11O27P	3081362	Moderate		Inter Info	[4], [2], [3]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[4], [2], [3]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[4], [2], [3]
D1560		Tetrabenazine	C19H27NO3	6018	Moderate		Inter Info	[4], [2], [3]
D1596		Tizanidine	C9H8ClN5S	5487	Moderate		Inter Info	[4], [2], [3]
D1616		Tramadol	C16H25NO2	33741	Moderate		Inter Info	[7], [3], [6]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[7], [3], [6]
D1638		Triflupromazine	C18H19F3N2S	5568	Moderate		Inter Info	[7], [3], [6]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[4], [2], [3]
D1683		Vasopressin	C46H65N15O12S2	644077	Moderate		Inter Info	[4], [2], [3]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Moderate		Inter Info	[4], [2], [3]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[7], [3], [6]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[4], [2], [3]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 63
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0012		Acetazolamide	C4H6N4O3S2	1986	Moderate		Inter Info	[5], [2], [3]
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[5], [2], [3]
D0058		Amiloride	C6H8ClN7O	16231	Moderate		Inter Info	[5], [2], [3]
D0138		Azilsartan medoxomil	C30H24N4O8	135409642	Moderate		Inter Info	[5], [2], [3]
D0156		Benazepril	C24H28N2O5	5362124	Moderate		Inter Info	[5], [2], [3]
D0158		Bendroflumethiazide	C15H14F3N3O4S2	2315	Moderate		Inter Info	[5], [2], [3]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[5], [2], [3]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[5], [2], [3]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[5], [2], [3]
D0254		Captopril	C9H15NO3S	44093	Moderate		Inter Info	[5], [2], [3]
D0298		Celecoxib	C17H14F3N3O2S	2662	Moderate		Inter Info	[5], [2], [3]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[5], [2], [3]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[5], [2], [3]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[5], [2], [3]
D0479		Diclofenamide	C6H6Cl2N2O4S2	3038	Moderate		Inter Info	[5], [2], [3]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[5], [2], [3]
D0567		Enalapril	C20H28N2O5	5388962	Moderate		Inter Info	[5], [2], [3]
D0587		Eprosartan	C23H24N2O4S	5281037	Moderate		Inter Info	[5], [2], [3]
D0624		Etodolac	C17H21NO3	3308	Moderate		Inter Info	[5], [2], [3]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[5], [2], [3]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[5], [2], [3]
D0695		Fosinopril	C30H46NO7P	55891	Moderate		Inter Info	[5], [2], [3]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[5], [2], [3]
D0771		Hydrochlorothiazide	C7H8ClN3O4S2	3639	Moderate		Inter Info	[5], [2], [3]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[5], [2], [3]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[5], [2], [3]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[5], [2], [3]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[5], [2], [3]
D0844		Irbesartan	C25H28N6O	3749	Moderate		Inter Info	[5], [2], [3]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[5], [2], [3]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[5], [2], [3]
D0938		Lisinopril	C21H31N3O5	5362119	Moderate		Inter Info	[5], [2], [3]
D0954		Losartan	C22H23ClN6O	3961	Moderate		Inter Info	[5], [2], [3]
D0978		Mannitol	C6H14O6	6251	Moderate		Inter Info	[5], [2], [3]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[5], [2], [3]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[5], [2], [3]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[5], [2], [3]
D1018		Methazolamide	C5H8N4O3S2	4100	Moderate		Inter Info	[5], [2], [3]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[5], [2], [3]
D1082		Moexipril	C27H34N2O7	91270	Moderate		Inter Info	[5], [2], [3]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[5], [2], [3]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[5], [2], [3]
D1170		Olmesartan	C24H26N6O3	158781	Moderate		Inter Info	[5], [2], [3]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[5], [2], [3]
D1256		Perindopril	C19H32N2O5	107807	Moderate		Inter Info	[5], [2], [3]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[5], [2], [3]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[5], [2], [3]
D1369		Quinapril	C25H30N2O5	54892	Moderate		Inter Info	[5], [2], [3]
D1379		Ramipril	C23H32N2O5	5362129	Moderate		Inter Info	[5], [2], [3]
D1421		Rofecoxib	C17H14O4S	5090	Moderate		Inter Info	[5], [2], [3]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[5], [2], [3]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[5], [2], [3]
D0331		Choline salicylate	C12H19NO4	54686350	Moderate		Inter Info	[5], [2], [3]
D1501		Spironolactone	C24H32O4S	5833	Moderate		Inter Info	[5], [2], [3]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[5], [2], [3]
D1545		Telmisartan	C33H30N4O2	65999	Moderate		Inter Info	[5], [2], [3]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[5], [2], [3]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[5], [2], [3]
D1631		Triamterene	C12H11N7	5546	Moderate		Inter Info	[5], [2], [3]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[5], [2], [3]
D1668		Urea	CH4N2O	1176	Moderate		Inter Info	[5], [2], [3]
D1674		Valdecoxib	C16H14N2O3S	119607	Moderate		Inter Info	[5], [2], [3]
D1679		Valsartan	C24H29N5O3	60846	Moderate		Inter Info	[5], [2], [3]

References
1	Hill AG, Parry BR "Hypokalaemia following bowel cleansing with sodium phosphate." N Z Med J 109 (1996): 347. [PMID: 8862361]
2	Product Information. Suclear (polyethylene glycol 3350 with electrolytes). Braintree Laboratories, Braintree, MA.
3	Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates). Braintree Laboratories, Braintree, MA.
4	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
5	Product Information. Diovan (valsartan). Novartis Pharmaceuticals, East Hanover, NJ.
6	Salik JM, Kurtin P "Severe hyponatremia after colonoscopy preparation in a patient with the acquired immune deficiency syndrome." Am J Gastroenterol 80 (1985): 177-9. [PMID: 2983533]
7	Canadian Pharmacists Association.
8	Product Information. Golytely (polyethylene glycol electrolyte solution). Braintree, Braintree, MA.
9	Product Information. Prepopik (citric acid/Mg oxide/Na picosulfate). Ferring Pharmaceuticals Inc, Tarrytown, NY.
10	Product Information. MoviPrep (polyethylene glycol 3350 with electrolytes). Physicians Total Care, Tulsa, OK.
11	Soh JS, Kim KJ. Combination could be another tool for bowel preparation? World J Gastroenterol. 2016 Mar 14;22(10):2915-21. doi: 10.3748/wjg.v22.i10.2915.
12	Marcus FI "Pharmacokinetic interactions between digoxin and other drugs." J Am Coll Cardiol 5 (1985): a82-90. [PMID: 2985676]
13	McElnay JC, Harron DW, D'Arcy PF, Eagle MR "Interaction of digoxin with antacid constituents." Br Med J 1 (1978): 1554. [PMID: 656806]

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