Details of Drug

Drug General Information (ID: D1321)
Drug Name	Potassium Iodide
Drug Type	Small molecule
Drug Synonymous	potassium iodide; 7681-11-0; Potassium iodide (KI); Pima; Kali iodide; Thyro-Block; Knollide; Kisol; Asmofug E; Potassium diiodide; Potassium monoiodide; Thyroshield; Joptone; Potide; Kalii iodidum; Iodure de potassium; Potassium iodide (K2I2); Potassium iodide (K(I2)); Tripotassium triiodide; Caswell No. 694; iodopotassium; K1-N; Potassium iodide (K3I3); UNII-1C4QK22F9J; HSDB 5040; EINECS 231-659-4; NSC 77362; MFCD00011405; EPA Pesticide Chemical Code 075701; AI3-52931; CHEBI:8346; 1C4QK22F9J; Potassium salt of hydriodic acid; Iosat Click to Show/Hide
Disease Class	5A02: Thyrotoxicosis
Therapeutic Class	Minerals And Electrolytes
Structure
Structure	3D Structure		2D Structure
Formula	IK
InChI	1S/HI.K/h1H;/q;+1/p-1
InChIKey	NLKNQRATVPKPDG-UHFFFAOYSA-M
Canonical SMILES	[K+].[I-]
External Link
	Pubchem ID	4875
	CAS Number	7681-11-0
	CHEBI ID	8346
	TTD ID	D02URS

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM003 Affected organization distribution AM006 Pharmacodynamic additive effects BM014 Interference of cell/tissue uptake BM058 Increased risk of hyperkalemia
Relation Graph

Full list of drugs interacting with Potassium Iodide
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1822		Iodide I-123	I-	135300	Moderate		Inter Info	[60], [66], [67]
Pharmacodynamic additive effects
	Increased risk of hyperkalemia					Drug Num: 41
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0156		Benazepril	C24H28N2O5	5362124	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0254		Captopril	C9H15NO3S	44093	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0567		Enalapril	C20H28N2O5	5388962	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0585		Eplerenone	C24H30O6	443872	Major		Inter Info	[25], [26]
D0587		Eprosartan	C23H24N2O4S	5281037	Major		Inter Info	[14], [27], [18], [16], [28], [3], [4], [9], [10], [7], [20]
D0695		Fosinopril	C30H46NO7P	55891	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0844		Irbesartan	C25H28N6O	3749	Major		Inter Info	[16], [27], [14], [20], [28], [4], [10], [7], [9], [18], [3]
D0938		Lisinopril	C21H31N3O5	5362119	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0954		Losartan	C22H23ClN6O	3961	Major		Inter Info	[14], [27], [18], [16], [28], [3], [4], [9], [10], [7], [20]
D1082		Moexipril	C27H34N2O7	91270	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D1170		Olmesartan	C24H26N6O3	158781	Major		Inter Info	[14], [27], [18], [16], [28], [3], [4], [9], [10], [7], [20]
D1256		Perindopril	C19H32N2O5	107807	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D0138		Azilsartan medoxomil	C30H24N4O8	135409642	Major		Inter Info	[14], [27], [18], [16], [28], [3], [4], [9], [10], [7], [20]
D1369		Quinapril	C25H30N2O5	54892	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D1379		Ramipril	C23H32N2O5	5362129	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D1545		Telmisartan	C33H30N4O2	65999	Major		Inter Info	[14], [27], [18], [16], [28], [3], [4], [9], [10], [7], [20]
D1618		Trandolapril	C24H34N2O5	5484727	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]
D1645		Trimethoprim	C14H18N4O3	5578	Major		Inter Info	[29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [7], [10], [43], [44], [45], [46], [47], [48], [49], [4], [50], [51], [9], [25], [52], [53], [54], [55], [56], [57], [58]
D1679		Valsartan	C24H29N5O3	60846	Major		Inter Info	[14], [27], [18], [16], [28], [3], [4], [9], [10], [7], [20]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0624		Etodolac	C17H21NO3	3308	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[61], [59], [60]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D1300		Piroxicam	C15H13N3O4S	54676228	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D0038		Aliskiren	C30H53N3O6	5493444	Moderate		Inter Info	[65]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[59], [60], [61], [62], [63], [64]
D1608		Tolvaptan	C26H25ClN2O3	216237	Moderate		Inter Info	[68]

References
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26	Product Information. Inspra (eplerenone). Searle, Chicago, IL.
27	Product Information. Cozaar (losartan). Merck & Co, Inc, West Point, PA.
28	Product Information. Diovan (valsartan). Novartis Pharmaceuticals, East Hanover, NJ.
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47	Product Information. Bactrim (trimethoprim-sulfamethoxazole). Roche Laboratories, Nutley, NJ.
48	Mori H, Kuroda Y, Imamura S, et al "Hyponatremia and/or hyperkalemia in patients treated with the standard dose of trimethoprim-sulfamethoxazole." Intern Med 42 (2003): 665-9. [PMID: 12924488]
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59	Product Information. Potassium Chloride ER (potassium chloride). Zydus Pharmaceuticals (USA) Inc, Princeton, NJ.
60	Cerner Multum, Inc. "Australian Product Information.".
61	Product Information. K-Phos Original (potassium acid phosphate). Beach Pharmaceuticals, Tampa, FL.
62	Product Information. Potassium Chloride (potassium chloride). Pharmaceutical Assoc Inc Div Beach Products, Greenville, SC.
63	Product Information. Phospho-Trin 250 Neutral (potassium phosphate-sodium phosphate). Patrin Pharma, Skokie, IL.
64	Product Information. SSKI (potassium iodide). Upsher-Smith Laboratories Inc, Minneapolis, MN.
65	Product Information. Tekturna (aliskiren). Novartis Pharmaceuticals, East Hanover, NJ.
66	Product Information. Sodium Iodide I-123 (sodium iodide I-123). GE Healthcare, Princeton, NJ.
67	Product Information. Visipaque (iodixanol). Nycomed Inc, Princeton, NJ.
68	Product Information. Samsca (tolvaptan). Otsuka American Pharmaceuticals Inc, Rockville, MD.

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