Details of Drug

Drug General Information (ID: D1287)
Drug Name	Picosulfuric acid
Drug Type	Small molecule
Drug Synonymous	Picosulfuric acid; Picosulfate; UNII-95D580798S; 10040-34-3; 95D580798S; Picosulphate; sodium-picosulfate; CHEMBL1741134; SCHEMBL18552552; DTXSID70143251; ZINC3873921; Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate); DB09268; Bis(sulfuric acid)2-pyridinylmethylenebis(1,4-phenylene) ester Click to Show/Hide
Therapeutic Class	Vitamins
Structure
Structure	3D Structure		2D Structure
Formula	C18H15NO8S2
InChI	InChI=1S/C18H15NO8S2/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25/h1-12,18H,(H,20,21,22)(H,23,24,25)
InChIKey	UJIDKYTZIQTXPM-UHFFFAOYSA-N
Canonical SMILES	C1=CC=NC(=C1)C(C2=CC=C(C=C2)OS(=O)(=O)O)C3=CC=C(C=C3)OS(=O)(=O)O
External Link
External Link	Pubchem ID	5243

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM003 Affected organization distribution AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM002 Altered intestinal flora BM014 Interference of cell/tissue uptake BM054 Increased risk of GI mucosal injury/bleeding risk BM065 Increased risk of hypokalemia BM069 Increased risk of lowers seizure threshold BM081 Increased risk of ventricular arrhythmias BM107 Attenuated pharmacological effects (Unspecific) BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Picosulfuric acid
Affected gastrointestinal absorption
	Altered intestinal flora					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0139		Azithromycin	C38H72N2O12	447043	Moderate		Inter Info	[11], [12], [13]
D0358		Clofazimine	C27H22Cl2N4	2794	Moderate		Inter Info	[11], [12], [13]
D0597		Erythromycin	C37H67NO13	12560	Moderate		Inter Info	[11], [12], [13]
D1542		Telavancin	C80H106Cl2N11O27P	3081362	Moderate		Inter Info	[11], [12], [13]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[11], [12], [13]
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0670		Fludeoxyglucose (18F)	C6H11FO5	170049	Moderate		Inter Info	[17], [18], [19]
Pharmacodynamic additive effects
	Increased risk of GI mucosal injury/bleeding risk					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1308		Polyethylene glycol (3350 with electrolytes)	C2H6O2	174	Moderate		Inter Info	[3], [20], [21]
D1309		Polyethylene glycol (3350)	C2H6O2	174	Moderate		Inter Info	[3], [20], [21]
	Increased risk of hypokalemia					Drug Num: 12
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[14], [12], [15]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[14], [12], [15]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[14], [12], [15]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[14], [12], [15]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[14], [12], [15]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[14], [12], [15]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[14], [12], [15]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[14], [12], [15]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[14], [12], [15]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[14], [12], [15]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[14], [12], [15]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[14], [12], [15]
	Increased risk of lowers seizure threshold					Drug Num: 98
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0030		Aldesleukin	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0035		Alfentanil	C21H32N6O3	51263	Moderate		Inter Info	[3], [6], [4]
D0051		Amantadine	C10H17N	2130	Moderate		Inter Info	[3], [6], [4]
D0064		Aminophylline	C16H24N10O4	9433	Moderate		Inter Info	[3], [6], [4]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[3], [6], [4]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[3], [6], [4]
D0175		Bethanechol	C7H17N2O2+	2370	Moderate		Inter Info	[3], [6], [4]
D0191		Blinatumomab	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0202		Brexpiprazole	C25H27N3O2S	11978813	Moderate		Inter Info	[3], [6], [4]
D0220		Bupropion	C13H18ClNO	444	Moderate		Inter Info	[3], [6], [4]
D0226		Butorphanol	C21H29NO2	5361092	Moderate		Inter Info	[3], [6], [4]
D0262		Cariprazine	C21H32Cl2N4O	11154555	Moderate		Inter Info	[3], [6], [4]
D0377		Cocaine (nasal)	C17H21NO4	446220	Moderate		Inter Info	[3], [6], [4]
D0379		Codeine	C18H21NO3	5284371	Moderate		Inter Info	[3], [6], [4]
D0398		Cyclobenzaprine	C20H21N	2895	Moderate		Inter Info	[3], [6], [4]
D0412		Dalfampridine	C5H6N2	1727	Moderate		Inter Info	[3], [6], [4]
D0451		Desvenlafaxine	C16H25NO2	125017	Moderate		Inter Info	[3], [6], [4]
D0457		Dexfenfluramine	C12H16F3N	66265	Moderate		Inter Info	[3], [6], [4]
D0460		Dexmethylphenidate	C14H19NO2	154101	Moderate		Inter Info	[3], [4], [6]
D0465		Dextroamphetamine	C9H13N	5826	Moderate		Inter Info	[3], [6], [4]
D0470		Dezocine	C16H23NO	3033053	Moderate		Inter Info	[3], [6], [4]
D0471		Diamorphine	C21H23NO5	5462328	Moderate		Inter Info	[3], [4], [6]
D0486		Diethylpropion	C13H19NO	7029	Moderate		Inter Info	[3], [6], [4]
D0516		Donepezil	C24H29NO3	3152	Moderate		Inter Info	[3], [6], [4]
D0523		Doxapram	C24H30N2O2	3156	Moderate		Inter Info	[3], [6], [4]
D0533		Dronabinol	C21H30O2	16078	Moderate		Inter Info	[3], [6], [4]
D0539		Duloxetine	C18H19NOS	60835	Moderate		Inter Info	[3], [6], [4]
D0641		Fenfluramine	C12H16F3N	3337	Moderate		Inter Info	[3], [6], [4]
D0646		Fentanyl	C22H28N2O	3345	Moderate		Inter Info	[3], [6], [4]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[3], [6], [4]
D0707		Galantamine	C17H21NO3	9651	Moderate		Inter Info	[3], [6], [4]
D0772		Hydrocodone	C18H21NO3	5284569	Moderate		Inter Info	[3], [4], [6]
D0776		Hydromorphone	C17H19NO3	5284570	Moderate		Inter Info	[3], [6], [4]
D0821		Interferon alfa-2a, Recombinant	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0822		Interferon alfa-2b	C16H17Cl3I2N3NaO5S	71306834	Moderate		Inter Info	[3], [6], [4]
D0824		Interferon alfa-n1	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0825		Interferon alfa-n3	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0823		Interferon alfacon-1	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0826		Interferon beta-1a	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0827		Interferon beta-1b	NA	NA	Moderate		Inter Info	[3], [6], [4]
D0828		Interferon gamma-1b	NA	NA	Moderate		Inter Info	[3], [4], [6]
D0853		Isocarboxazid	C12H13N3O2	3759	Moderate		Inter Info	[3], [6], [4]
D0920		Levomilnacipran	C15H22N2O	6917779	Moderate		Inter Info	[3], [6], [4]
D0927		Lidocaine	C14H22N2O	3676	Moderate		Inter Info	[3], [4], [6]
D0932		Lindane	C6H6Cl6	727	Moderate		Inter Info	[3], [6], [4]
D0957		Loxapine	C18H18ClN3O	3964	Moderate		Inter Info	[3], [6], [4]
D0959		Lumateperone	C24H28FN3O	21302490	Moderate		Inter Info	[3], [6], [4]
D0961		Lurasidone	C28H36N4O2S	213046	Moderate		Inter Info	[3], [4], [6]
D0981		Mazindol	C16H13ClN2O	4020	Moderate		Inter Info	[3], [6], [4]
D1001		Meperidine	C15H21NO2	4058	Moderate		Inter Info	[3], [6], [4]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[3], [6], [4]
D1019		Methdilazine	C18H20N2S	14677	Moderate		Inter Info	[3], [6], [4]
D1039		Methylphenidate	C14H19NO2	4158	Moderate		Inter Info	[3], [6], [4]
D1046		Metoclopramide	C14H22ClN3O2	4168	Moderate		Inter Info	[3], [6], [4]
D1054		Mexiletine	C11H17NO	4178	Moderate		Inter Info	[3], [6], [4]
D1066		Milnacipran	C15H22N2O	65833	Moderate		Inter Info	[3], [6], [4]
D1084		Molindone	C16H24N2O2	23897	Moderate		Inter Info	[3], [6], [4]
D1089		Morphine	C17H19NO3	5288826	Moderate		Inter Info	[3], [6], [4]
D1090		Morphine (liposomal)	C17H19NO3	5288826	Moderate		Inter Info	[3], [4], [6]
D1093		Muromonab	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1100		Nalbuphine	C21H27NO4	5311304	Moderate		Inter Info	[3], [6], [4]
D1117		Nefazodone	C25H32ClN5O2	4449	Moderate		Inter Info	[3], [6], [4]
D1118		Nelarabine	C11H15N5O5	3011155	Moderate		Inter Info	[3], [6], [4]
D1122		Neostigmine	C12H19N2O2+	4456	Moderate		Inter Info	[3], [6], [4]
D1166		Olanzapine	C17H20N4S	135398745	Moderate		Inter Info	[3], [6], [4]
D1194		Oxamniquine	C14H21N3O3	4612	Moderate		Inter Info	[3], [6], [4]
D1201		Oxtriphylline	C12H21N5O3	656652	Moderate		Inter Info	[3], [6], [4]
D1203		Oxycodone	C18H21NO4	5284603	Moderate		Inter Info	[3], [6], [4]
D1208		Oxymorphone	C17H19NO4	5284604	Moderate		Inter Info	[3], [6], [4]
D1229		Paroxetine	C19H20FNO3	43815	Moderate		Inter Info	[3], [4], [6]
D1237		Peginterferon alfa-2a	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1238		Peginterferon alfa-2b	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1239		Peginterferon beta-1a	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1243		Pemoline	C9H8N2O2	4723	Moderate		Inter Info	[3], [6], [4]
D1247		Pentazocine	C19H27NO	441278	Moderate		Inter Info	[3], [6], [4]
D1262		Phendimetrazine	C12H17NO	30487	Moderate		Inter Info	[3], [6], [4]
D1270		Phentermine	C10H15N	4771	Moderate		Inter Info	[3], [6], [4]
D1281		Phenylpropanolamine	C9H13NO	26934	Moderate		Inter Info	[3], [6], [4]
D1285		Physostigmine	C15H21N3O2	5983	Moderate		Inter Info	[3], [6], [4]
D0054		Amifampridine	C5H7N3	5918	Moderate		Inter Info	[3], [6], [4]
D0095		Apalutamide	C21H15F4N5O2S	24872560	Moderate		Inter Info	[7], [3], [6]
D0940		Lithium carbonate	CLi2O3	11125	Moderate		Inter Info	[7], [3], [6]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[7], [3], [6]
D1183		Opium	NA	NA	Moderate		Inter Info	[3], [6], [4]
D1297		Piperazine	C4H10N2	4837	Moderate		Inter Info	[3], [6], [4]
D1355		Propiomazine	C20H24N2OS	4940	Moderate		Inter Info	[3], [6], [4]
D1390		Remifentanil	C20H28N2O5	60815	Moderate		Inter Info	[3], [6], [4]
D1406		Rimantadine	C12H21N	5071	Moderate		Inter Info	[3], [6], [4]
D1418		Rivastigmine	C14H22N2O2	77991	Moderate		Inter Info	[3], [6], [4]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[3], [6], [4]
D1512		Sufentanil	C22H30N2O2S	41693	Moderate		Inter Info	[3], [6], [4]
D1525		Tacrine	C13H14N2	1935	Moderate		Inter Info	[3], [6], [4]
D1535		Tapentadol	C14H23NO	9838022	Moderate		Inter Info	[3], [6], [4]
D1570		Theophylline	C7H8N4O2	2153	Moderate		Inter Info	[3], [6], [4]
D1572		Thiethylperazine	C22H29N3S2	5440	Moderate		Inter Info	[3], [6], [4]
D1576		Thiothixene	C23H29N3O2S2	941651	Moderate		Inter Info	[3], [6], [4]
D1620		Tranylcypromine	C9H11N	19493	Moderate		Inter Info	[3], [6], [4]
D1708		Vortioxetine	C18H22N2S	9966051	Moderate		Inter Info	[3], [6], [4]
	Increased risk of ventricular arrhythmias					Drug Num: 154
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0066		Amiodarone	C25H29I2NO3	2157	Major		Inter Info	[1], [2], [3]
D0107		Arsenic trioxide	As2O3	14888	Major		Inter Info	[1], [2], [3]
D0115		Astemizole	C28H31FN4O	2247	Major		Inter Info	[1], [2], [3]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Major		Inter Info	[1], [2], [3]
D0170		Bepridil	C24H34N2O	2351	Major		Inter Info	[1], [2], [3]
D0342		Cisapride	C23H29ClFN3O4	6917698	Major		Inter Info	[1], [2], [3]
D0370		Clozapine	C18H19ClN4	135398737	Major		Inter Info	[1], [2], [3]
D0508		Disopyramide	C21H29N3O	3114	Major		Inter Info	[1], [2], [3]
D0513		Dofetilide	C19H27N3O5S2	71329	Major		Inter Info	[1], [2], [3]
D0514		Dolasetron	C19H20N2O3	3033818	Major		Inter Info	[1], [2], [3]
D0534		Dronedarone	C31H44N2O5S	208898	Major		Inter Info	[1], [2], [3]
D0535		Droperidol	C22H22FN3O2	3168	Major		Inter Info	[1], [2], [3]
D0740		Grepafloxacin	C19H22FN3O3	72474	Major		Inter Info	[1], [2], [3]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Major		Inter Info	[1], [2], [3]
D0787		Ibutilide	C20H36N2O3S	60753	Major		Inter Info	[1], [2], [3]
D0909		Levacetylmethadol	C23H31NO2	15130	Major		Inter Info	[1], [2], [3]
D1010		Mesoridazine	C21H26N2OS2	4078	Major		Inter Info	[1], [2], [3]
D1017		Methadone	C21H27NO	4095	Major		Inter Info	[1], [2], [3]
D1136		Nilotinib	C28H22F3N7O	644241	Major		Inter Info	[1], [2], [3]
D1221		Panobinostat	C21H23N3O2	6918837	Major		Inter Info	[1], [2], [3]
D1292		Pimozide	C28H29F2N3O	16362	Major		Inter Info	[1], [2], [3]
D1343		Procainamide	C13H21N3O	4913	Major		Inter Info	[1], [2], [3]
D1371		Quinidine	C20H24N2O2	441074	Major		Inter Info	[1], [2], [3]
D1372		Quinine	C20H24N2O2	3034034	Major		Inter Info	[1], [2], [3]
D1444		Saquinavir	C38H50N6O5	441243	Major		Inter Info	[1], [2], [3]
D1498		Sotalol	C12H20N2O3S	5253	Major		Inter Info	[1], [2], [3]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Major		Inter Info	[1], [2], [3]
D1555		Terfenadine	C32H41NO2	5405	Major		Inter Info	[1], [2], [3]
D1574		Thioridazine	C21H26N2S2	5452	Major		Inter Info	[1], [2], [3]
D1612		Toremifene	C26H28ClNO	3005573	Major		Inter Info	[1], [2], [3]
D1681		Vandetanib	C22H24BrFN4O2	3081361	Major		Inter Info	[1], [2], [3]
D1726		Ziprasidone	C21H21ClN4OS	60854	Major		Inter Info	[1], [2], [3]
D0003		Abarelix	C72H95ClN14O14	16131215	Moderate		Inter Info	[4], [2], [3]
D0007		Abiraterone	C24H31NO	132971	Moderate		Inter Info	[4], [2], [3]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[4], [2], [3]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[7], [3], [6]
D0067		Amisulpride	C17H27N3O4S	2159	Moderate		Inter Info	[7], [3], [6]
D0068		Amitriptyline	C20H23N	2160	Moderate		Inter Info	[7], [3], [6]
D0072		Amoxapine	C17H16ClN3O	2170	Moderate		Inter Info	[7], [3], [6]
D0084		Anagrelide	C10H7Cl2N3O	135409400	Moderate		Inter Info	[4], [2], [3]
D0097		Apomorphine	C17H17NO2	6005	Moderate		Inter Info	[4], [2], [3]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[7], [3], [6]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[7], [3], [6]
D0180		Bicalutamide	C18H14F4N2O4S	2375	Moderate		Inter Info	[4], [2], [3]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[7], [3], [6]
D0230		Cabozantinib	C28H24FN3O5	25102847	Moderate		Inter Info	[4], [2], [3]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[7], [3], [6]
D0336		Cilostazol	C20H27N5O2	2754	Moderate		Inter Info	[4], [2], [3]
D0345		Citalopram	C20H21FN2O	2771	Moderate		Inter Info	[7], [3], [6]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[7], [3], [6]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Moderate		Inter Info	[4], [2], [3]
D0429		Daunorubicin	C27H29NO10	30323	Moderate		Inter Info	[4], [2], [3]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Moderate		Inter Info	[4], [2], [3]
D0437		Degarelix	C82H103ClN18O16	16136245	Moderate		Inter Info	[4], [2], [3]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[7], [3], [6]
D0467		Dextropropoxyphene	C22H29NO2	10100	Moderate		Inter Info	[7], [3], [6]
D0526		Doxepin (topical)	C19H21NO	667477	Moderate		Inter Info	[7], [3], [6]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[4], [2], [3]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[4], [2], [3]
D0554		Efavirenz	C14H9ClF3NO2	64139	Moderate		Inter Info	[7], [3], [6]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[7], [3], [6]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[4], [2], [3]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[4], [2], [3]
D0599		Escitalopram	C20H21FN2O	146570	Moderate		Inter Info	[7], [3], [6]
D0632		Ezogabine	C16H18FN3O2	121892	Moderate		Inter Info	[4], [2], [3]
D0664		Flecainide	C17H20F6N2O3	3356	Moderate		Inter Info	[4], [2], [3]
D0667		Fluconazole	C13H12F2N6O	3365	Moderate		Inter Info	[4], [2], [3]
D0676		Fluoxetine	C17H18F3NO	3386	Moderate		Inter Info	[7], [3], [6]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[7], [3], [6]
D0682		Flutamide	C11H11F3N2O3	3397	Moderate		Inter Info	[4], [2], [3]
D0694		Foscarnet	CH3O5P	3415	Moderate		Inter Info	[7], [3], [6]
D0737		Goserelin	C59H84N18O14	5311128	Moderate		Inter Info	[4], [2], [3]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[4], [2], [3]
D0750		Haloperidol	C21H23ClFNO2	3559	Moderate		Inter Info	[7], [3], [6]
D0751		Halothane	C2HBrClF3	3562	Moderate		Inter Info	[4], [2], [3]
D0758		Histrelin	C66H86N18O12	25077993	Moderate		Inter Info	[4], [2], [3]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[7], [3], [6]
D0781		Hydroxyzine	C21H27ClN2O2	3658	Moderate		Inter Info	[4], [2], [3]
D0788		Idarubicin	C26H27NO9	42890	Moderate		Inter Info	[4], [2], [3]
D0791		Iloperidone	C24H27FN2O4	71360	Moderate		Inter Info	[7], [3], [6]
D0806		Inotuzumab ozogamicin	NA	NA	Moderate		Inter Info	[4], [2], [3]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[4], [2], [3]
D0903		Lenvatinib	C21H19ClN4O4	9823820	Moderate		Inter Info	[4], [2], [3]
D0908		Leuprolide	C59H84N16O12	657181	Moderate		Inter Info	[4], [2], [3]
D0942		Lofexidine	C11H12Cl2N2O	30668	Moderate		Inter Info	[4], [2], [3]
D0979		Maprotiline	C20H23N	4011	Moderate		Inter Info	[7], [3], [6]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[7], [3], [6]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[7], [3], [6]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[4], [2], [3]
D1063		Mifepristone	C29H35NO2	55245	Moderate		Inter Info	[4], [2], [3]
D1075		Mirtazapine	C17H19N3	4205	Moderate		Inter Info	[7], [3], [6]
D1137		Nilutamide	C12H10F3N3O4	4493	Moderate		Inter Info	[4], [2], [3]
D1158		Nortriptyline	C19H21N	4543	Moderate		Inter Info	[7], [3], [6]
D1181		Ondansetron	C18H19N3O	4595	Moderate		Inter Info	[4], [2], [3]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[4], [2], [3]
D1210		Oxytocin	C43H66N12O12S2	439302	Moderate		Inter Info	[4], [2], [3]
D1215		Paliperidone	C23H27FN4O3	115237	Moderate		Inter Info	[7], [3], [6]
D1216		Palonosetron	C19H24N2O	6337614	Moderate		Inter Info	[4], [2], [3]
D1230		Pasireotide	C58H66N10O9	9941444	Moderate		Inter Info	[4], [2], [3]
D1246		Pentamidine	C19H24N4O2	4735	Moderate		Inter Info	[4], [2], [3]
D1254		Perflutren	C3F8	6432	Moderate		Inter Info	[4], [2], [3]
D1257		Perphenazine	C21H26ClN3OS	4748	Moderate		Inter Info	[7], [3], [6]
D0452		Deutetrabenazine	C19H27NO3	73437646	Moderate		Inter Info	[4], [2], [3]
D0569		Encorafenib	C22H27ClFN7O4S	50922675	Moderate		Inter Info	[4], [2], [3]
D0577		Entrectinib	C31H34F2N6O2	25141092	Moderate		Inter Info	[4], [2], [3]
D0700		Fostemsavir	C25H26N7O8P	11319217	Moderate		Inter Info	[4], [2], [3]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[4], [2], [3]
D0725		Glasdegib	C21H22N6O	25166913	Moderate		Inter Info	[4], [2], [3]
D0872		Ivosidenib	C28H22ClF3N6O3	71657455	Moderate		Inter Info	[4], [2], [3]
D0899		Lefamulin	C28H45NO5S	25185057	Moderate		Inter Info	[4], [2], [3]
D0965		Macimorelin	C26H30N6O3	9804938	Moderate		Inter Info	[4], [2], [3]
D1190		Osimertinib	C28H33N7O2	71496458	Moderate		Inter Info	[4], [2], [3]
D1211		Ozanimod	C23H24N4O3	52938427	Moderate		Inter Info	[4], [2], [3]
D1302		Pitolisant	C17H26ClNO	9948102	Moderate		Inter Info	[4], [2], [3]
D1388		Relugolix	C29H27F2N7O5S	10348973	Moderate		Inter Info	[4], [2], [3]
D1398		Ribociclib	C23H30N8O	44631912	Moderate		Inter Info	[4], [2], [3]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[4], [2], [3]
D1474		Siponimod	C29H35F3N2O3	44599207	Moderate		Inter Info	[4], [2], [3]
D1634		Triclabendazole	C14H9Cl3N2OS	50248	Moderate		Inter Info	[4], [2], [3]
D1673		Valbenazine	C24H38N2O4	24795069	Moderate		Inter Info	[4], [2], [3]
D1290		Pimavanserin	C25H34FN3O2	10071196	Moderate		Inter Info	[4], [2], [3]
D1315		Posaconazole	C37H42F2N8O4	468595	Moderate		Inter Info	[4], [2], [3]
D1339		Primaquine	C15H21N3O	4908	Moderate		Inter Info	[4], [2], [3]
D1342		Probucol	C31H48O2S2	4912	Moderate		Inter Info	[4], [2], [3]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[7], [3], [6]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[7], [3], [6]
D1353		Propafenone	C21H27NO3	4932	Moderate		Inter Info	[4], [2], [3]
D1356		Propofol	C12H18O	4943	Moderate		Inter Info	[4], [2], [3]
D1361		Protriptyline	C19H21N	4976	Moderate		Inter Info	[7], [3], [6]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[7], [3], [6]
D1383		Ranolazine	C24H33N3O4	56959	Moderate		Inter Info	[4], [2], [3]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[7], [3], [6]
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[4], [2], [3]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[4], [2], [3]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[7], [3], [6]
D1463		Sevoflurane	C4H3F7O	5206	Moderate		Inter Info	[4], [2], [3]
D1491		Solifenacin	C23H26N2O2	154059	Moderate		Inter Info	[4], [2], [3]
D1497		Sorafenib	C21H16ClF3N4O3	216239	Moderate		Inter Info	[4], [2], [3]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[4], [2], [3]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[4], [2], [3]
D1533		Tamoxifen	C26H29NO	2733526	Moderate		Inter Info	[4], [2], [3]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[4], [2], [3]
D1560		Tetrabenazine	C19H27NO3	6018	Moderate		Inter Info	[4], [2], [3]
D1616		Tramadol	C16H25NO2	33741	Moderate		Inter Info	[7], [3], [6]
D1624		Trazodone	C19H22ClN5O	5533	Moderate		Inter Info	[7], [3], [6]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[7], [3], [6]
D1638		Triflupromazine	C18H19F3N2S	5568	Moderate		Inter Info	[7], [3], [6]
D1647		Trimipramine	C20H26N2	5584	Moderate		Inter Info	[7], [3], [6]
D1651		Triptorelin	C64H82N18O13	25074470	Moderate		Inter Info	[4], [2], [3]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[4], [2], [3]
D1683		Vasopressin	C46H65N15O12S2	644077	Moderate		Inter Info	[4], [2], [3]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Moderate		Inter Info	[4], [2], [3]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[7], [3], [6]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[4], [2], [3]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 66
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0012		Acetazolamide	C4H6N4O3S2	1986	Moderate		Inter Info	[5], [2], [3]
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[5], [2], [3]
D0058		Amiloride	C6H8ClN7O	16231	Moderate		Inter Info	[5], [2], [3]
D0138		Azilsartan medoxomil	C30H24N4O8	135409642	Moderate		Inter Info	[5], [2], [3]
D0156		Benazepril	C24H28N2O5	5362124	Moderate		Inter Info	[5], [2], [3]
D0158		Bendroflumethiazide	C15H14F3N3O4S2	2315	Moderate		Inter Info	[5], [2], [3]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[5], [2], [3]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[5], [2], [3]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[5], [2], [3]
D0254		Captopril	C9H15NO3S	44093	Moderate		Inter Info	[5], [2], [3]
D0298		Celecoxib	C17H14F3N3O2S	2662	Moderate		Inter Info	[5], [2], [3]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[5], [2], [3]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[5], [2], [3]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[5], [2], [3]
D0479		Diclofenamide	C6H6Cl2N2O4S2	3038	Moderate		Inter Info	[5], [2], [3]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[5], [2], [3]
D0567		Enalapril	C20H28N2O5	5388962	Moderate		Inter Info	[5], [2], [3]
D0587		Eprosartan	C23H24N2O4S	5281037	Moderate		Inter Info	[5], [2], [3]
D0613		Etacrynic acid	C13H12Cl2O4	3278	Moderate		Inter Info	[5], [2], [3]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[5], [2], [3]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[5], [2], [3]
D0695		Fosinopril	C30H46NO7P	55891	Moderate		Inter Info	[5], [2], [3]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[5], [2], [3]
D0771		Hydrochlorothiazide	C7H8ClN3O4S2	3639	Moderate		Inter Info	[5], [2], [3]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[5], [2], [3]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[5], [2], [3]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[5], [2], [3]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[5], [2], [3]
D0844		Irbesartan	C25H28N6O	3749	Moderate		Inter Info	[5], [2], [3]
D0845		Irinotecan	C33H38N4O6	60838	Moderate		Inter Info	[16]
D0846		Irinotecan (liposomal)	C33H38N4O6	60838	Moderate		Inter Info	[16]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[5], [2], [3]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[5], [2], [3]
D0938		Lisinopril	C21H31N3O5	5362119	Moderate		Inter Info	[5], [2], [3]
D0978		Mannitol	C6H14O6	6251	Moderate		Inter Info	[5], [2], [3]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[5], [2], [3]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[5], [2], [3]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[5], [2], [3]
D1018		Methazolamide	C5H8N4O3S2	4100	Moderate		Inter Info	[5], [2], [3]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[5], [2], [3]
D1082		Moexipril	C27H34N2O7	91270	Moderate		Inter Info	[5], [2], [3]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[5], [2], [3]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[5], [2], [3]
D1170		Olmesartan	C24H26N6O3	158781	Moderate		Inter Info	[5], [2], [3]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[5], [2], [3]
D1256		Perindopril	C19H32N2O5	107807	Moderate		Inter Info	[5], [2], [3]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[5], [2], [3]
D1300		Piroxicam	C15H13N3O4S	54676228	Moderate		Inter Info	[5], [2], [3]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[5], [2], [3]
D1369		Quinapril	C25H30N2O5	54892	Moderate		Inter Info	[5], [2], [3]
D1379		Ramipril	C23H32N2O5	5362129	Moderate		Inter Info	[5], [2], [3]
D1421		Rofecoxib	C17H14O4S	5090	Moderate		Inter Info	[5], [2], [3]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[5], [2], [3]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[5], [2], [3]
D1501		Spironolactone	C24H32O4S	5833	Moderate		Inter Info	[5], [2], [3]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[5], [2], [3]
D1545		Telmisartan	C33H30N4O2	65999	Moderate		Inter Info	[5], [2], [3]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[5], [2], [3]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[5], [2], [3]
D1618		Trandolapril	C24H34N2O5	5484727	Moderate		Inter Info	[5], [2], [3]
D1631		Triamterene	C12H11N7	5546	Moderate		Inter Info	[5], [2], [3]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[5], [2], [3]
D1668		Urea	CH4N2O	1176	Moderate		Inter Info	[5], [2], [3]
D1674		Valdecoxib	C16H14N2O3S	119607	Moderate		Inter Info	[5], [2], [3]
D1679		Valsartan	C24H29N5O3	60846	Moderate		Inter Info	[5], [2], [3]
D0929		Linaclotide	C59H79N15O21S6	16158208	Minor		Inter Info	[22], [23]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 98
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0056		Amikacin	C22H43N5O13	37768	Moderate		Inter Info	[8], [9], [10]
D0057		Amikacin (liposome)	C22H43N5O13	37768	Moderate		Inter Info	[8], [9], [10]
D0065		Aminosalicylic acid	C7H7NO3	4649	Moderate		Inter Info	[8], [9], [10]
D0073		Amoxicillin	C16H19N3O5S	33613	Moderate		Inter Info	[8], [9], [10]
D0079		Ampicillin	C16H19N3O4S	6249	Moderate		Inter Info	[8], [9], [10]
D0121		Atovaquone	C22H19ClO3	74989	Moderate		Inter Info	[8], [9], [10]
D0140		Aztreonam	C13H17N5O8S2	5742832	Moderate		Inter Info	[8], [9], [10]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[8], [9], [10]
D0142		Bacitracin	C66H103N17O16S	10909430	Moderate		Inter Info	[8], [9], [10]
D0167		Benzylpenicillin	C16H18N2O4S	5904	Moderate		Inter Info	[8], [9], [10]
D0168		Benzylpenicillin (potassium)	C16H18N2O4S	5904	Moderate		Inter Info	[8], [9], [10]
D0169		Benzylpenicillin (sodium)	C16H18N2O4S	5904	Moderate		Inter Info	[8], [9], [10]
D0252		Capreomycin	C50H88N28O15	3000502	Moderate		Inter Info	[8], [9], [10]
D0257		Carbenicillin	C17H18N2O6S	20824	Moderate		Inter Info	[8], [9], [10]
D0271		Cefaclor	C15H14ClN3O4S	51039	Moderate		Inter Info	[8], [9], [10]
D0272		Cefadroxil	C16H17N3O5S	47965	Moderate		Inter Info	[8], [9], [10]
D0273		Cefalotin	C16H16N2O6S2	6024	Moderate		Inter Info	[8], [9], [10]
D0274		Cefamandole	C18H18N6O5S2	456255	Moderate		Inter Info	[8], [9], [10]
D0275		Cefapirin	C17H17N3O6S2	30699	Moderate		Inter Info	[8], [9], [10]
D0276		Cefazolin	C14H14N8O4S3	33255	Moderate		Inter Info	[8], [9], [10]
D0279		Cefepime	C19H24N6O5S2	5479537	Moderate		Inter Info	[8], [9], [10]
D0281		Cefixime	C16H15N5O7S2	5362065	Moderate		Inter Info	[8], [9], [10]
D0282		Cefmetazole	C15H17N7O5S3	42008	Moderate		Inter Info	[8], [9], [10]
D0283		Cefonicid	C18H18N6O8S3	43594	Moderate		Inter Info	[8], [9], [10]
D0284		Cefoperazone	C25H27N9O8S2	44187	Moderate		Inter Info	[8], [9], [10]
D0285		Cefotaxime	C16H17N5O7S2	5742673	Moderate		Inter Info	[8], [9], [10]
D0286		Cefotetan	C17H17N7O8S4	53025	Moderate		Inter Info	[8], [9], [10]
D0287		Cefoxitin	C16H17N3O7S2	441199	Moderate		Inter Info	[8], [9], [10]
D0288		Cefpodoxime	C15H17N5O6S2	6335986	Moderate		Inter Info	[8], [9], [10]
D0289		Cefprozil	C18H19N3O5S	5281006	Moderate		Inter Info	[8], [9], [10]
D0290		Cefradine	C16H19N3O4S	38103	Moderate		Inter Info	[8], [9], [10]
D0291		Ceftaroline fosamil	C22H21N8O8PS4	9852981	Moderate		Inter Info	[8], [9], [10]
D0292		Ceftazidime	C22H22N6O7S2	5481173	Moderate		Inter Info	[8], [9], [10]
D0293		Ceftibuten	C15H14N4O6S2	5282242	Moderate		Inter Info	[8], [9], [10]
D0294		Ceftizoxime	C13H13N5O5S2	6533629	Moderate		Inter Info	[8], [9], [10]
D0296		Ceftriaxone	C18H18N8O7S3	5479530	Moderate		Inter Info	[8], [9], [10]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[8], [9], [10]
D0354		Clindamycin	C18H33ClN2O5S	446598	Moderate		Inter Info	[8], [9], [10]
D0369		Cloxacillin	C19H18ClN3O5S	6098	Moderate		Inter Info	[8], [9], [10]
D0383		Colistimethate	C58H105N16O28S5-5	70789202	Moderate		Inter Info	[8], [9], [10]
D0401		Cycloserine	C3H6N2O2	6234	Moderate		Inter Info	[8], [9], [10]
D0411		Dalbavancin	C88H100Cl2N10O28	16134627	Moderate		Inter Info	[8], [9], [10]
D0419		Dapsone	C12H12N2O2S	2955	Moderate		Inter Info	[8], [9], [10]
D0421		Daptomycin	C72H101N17O26	16134395	Moderate		Inter Info	[8], [9], [10]
D0480		Dicloxacillin	C19H17Cl2N3O5S	18381	Moderate		Inter Info	[8], [9], [10]
D0519		Doripenem	C15H24N4O6S2	73303	Moderate		Inter Info	[8], [9], [10]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[8], [9], [10]
D0596		Ertapenem	C22H25N3O7S	150610	Moderate		Inter Info	[8], [9], [10]
D0616		Ethambutol	C10H24N2O2	14052	Moderate		Inter Info	[8], [9], [10]
D1731		Ethionamide	C8H10N2S	2761171	Moderate		Inter Info	[8], [9], [10]
D0658		Fidaxomicin	C52H74Cl2O18	10034073	Moderate		Inter Info	[8], [9], [10]
D0718		Gentamicin	C21H43N5O7	3467	Moderate		Inter Info	[8], [9], [10]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[8], [9], [10]
D0876		Kanamycin	C18H36N4O11	6032	Moderate		Inter Info	[8], [9], [10]
D0931		Lincomycin	C18H34N2O6S	3000540	Moderate		Inter Info	[8], [9], [10]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[8], [9], [10]
D0949		Loracarbef	C16H16ClN3O4	5284585	Moderate		Inter Info	[8], [9], [10]
D1008		Meropenem	C17H25N3O5S	441130	Moderate		Inter Info	[8], [9], [10]
D1020		Methenamine	C6H12N4	4101	Moderate		Inter Info	[8], [9], [10]
D1044		Meticillin	C17H20N2O6S	6087	Moderate		Inter Info	[8], [9], [10]
D1055		Mezlocillin	C21H25N5O8S2	656511	Moderate		Inter Info	[8], [9], [10]
D1099		Nafcillin	C21H22N2O5S	8982	Moderate		Inter Info	[8], [9], [10]
D1120		Neomycin	C23H46N6O13	8378	Moderate		Inter Info	[8], [9], [10]
D1126		Netilmicin	C21H41N5O7	441306	Moderate		Inter Info	[8], [9], [10]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Moderate		Inter Info	[8], [9], [10]
D1159		Novobiocin	C31H36N2O11	54675769	Moderate		Inter Info	[8], [9], [10]
D1186		Oritavancin	C86H97Cl3N10O26	16136912	Moderate		Inter Info	[8], [9], [10]
D1192		Oxacillin	C19H19N3O5S	6196	Moderate		Inter Info	[8], [9], [10]
D1228		Paromomycin	C23H45N5O14	165580	Moderate		Inter Info	[8], [9], [10]
D1268		Phenoxymethylpenicillin	C16H18N2O5S	6869	Moderate		Inter Info	[8], [9], [10]
D0162		Benznidazole	C12H12N4O3	31593	Moderate		Inter Info	[8], [9], [10]
D0280		Cefiderocol	C30H34ClN7O10S2	77843966	Moderate		Inter Info	[8], [9], [10]
D0589		Eravacycline	C27H31FN4O8	54726192	Moderate		Inter Info	[8], [9], [10]
D1304		Plazomicin	C25H48N6O10	42613186	Moderate		Inter Info	[8], [9], [10]
D1452		Secnidazole	C7H11N3O3	71815	Moderate		Inter Info	[8], [9], [10]
D1539		Tedizolid	C17H15FN6O3	11234049	Moderate		Inter Info	[8], [9], [10]
D1653		Troleandomycin	C41H67NO15	202225	Moderate		Inter Info	[8], [9], [10]
D1296		Piperacillin	C23H27N5O7S	43672	Moderate		Inter Info	[8], [9], [10]
D1310		Polymyxin B	C56H98N16O13	49800004	Moderate		Inter Info	[8], [9], [10]
D1364		Pyrazinamide	C5H5N3O	1046	Moderate		Inter Info	[8], [9], [10]
D1399		Rifabutin	C46H62N4O11	135398743	Moderate		Inter Info	[8], [9], [10]
D1400		Rifampicin	C43H58N4O12	135398735	Moderate		Inter Info	[8], [9], [10]
D1401		Rifapentine	C47H64N4O12	135403821	Moderate		Inter Info	[8], [9], [10]
D1402		Rifaximin	C43H51N3O11	6436173	Moderate		Inter Info	[8], [9], [10]
D1500		Spectinomycin	C14H24N2O7	15541	Moderate		Inter Info	[8], [9], [10]
D1507		Streptomycin	C21H39N7O12	19649	Moderate		Inter Info	[8], [9], [10]
D1513		Sulfadiazine	C10H10N4O2S	5215	Moderate		Inter Info	[8], [9], [10]
D1514		Sulfadoxine	C12H14N4O4S	17134	Moderate		Inter Info	[8], [9], [10]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Moderate		Inter Info	[8], [9], [10]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Moderate		Inter Info	[8], [9], [10]
D1519		Sulfisoxazole	C11H13N3O3S	5344	Moderate		Inter Info	[8], [9], [10]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[8], [9], [10]
D1580		Ticarcillin	C15H16N2O6S2	36921	Moderate		Inter Info	[8], [9], [10]
D1582		Tigecycline	C29H39N5O8	54686904	Moderate		Inter Info	[8], [9], [10]
D1597		Tobramycin	C18H37N5O9	36294	Moderate		Inter Info	[8], [9], [10]
D1645		Trimethoprim	C14H18N4O3	5578	Moderate		Inter Info	[8], [9], [10]
D1646		Trimetrexate	C19H23N5O3	5583	Moderate		Inter Info	[8], [9], [10]
D1680		Vancomycin	C66H75Cl2N9O24	14969	Moderate		Inter Info	[8], [9], [10]

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