Details of Drug

Details of Drug

 Drug General Information (ID: D0615)
  Drug Name
Etelcalcetide
  Drug Type Small molecule
  Drug Synonymous
Velcalcetide; Parsabiv; UNII-60ME133FJB; 1262780-97-1; 60ME133FJB; etelcalcetide HCl; Etelcalcetide [USAN:INN]; Etelcalcetide (USAN/INN); Etelcalcetide Hydrochloride(AMG-416)
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  Disease Class 5A51: Hyper-parathyroidism; 2A37: Myelodysplastic syndrome
  Therapeutic Class Calcimimetics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C38H73N21O10S2
  InChI 1S/C38H73N21O10S2/c1-18(28(62)56-22(27(40)61)8-4-12-49-35(41)42)53-30(64)23(9-5-13-50-36(43)44)58-32(66)25(11-7-15-52-38(47)48)59-31(65)24(10-6-14-51-37(45)46)57-29(63)19(2)54-33(67)26(55-20(3)60)17-71-70-16-21(39)34(68)69/h18-19,21-26H,4-17,39H2,1-3H3,(H2,40,61)(H,53,64)(H,54,67)(H,55,60)(H,56,62)(H,57,63)(H,58,66)(H,59,65)(H,68,69)(H4,41,42,49)(H4,43,44,50)(H4,45,46,51)(H4,47,48,52)/t18-,19-,21+,22-,23-,24-,25-,26-/m1/s1
  InChIKey ANIAZGVDEUQPRI-ZJQCGQFWSA-N
  Canonical SMILES CC(C(=O)NC(CCCN=C(N)N)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CSSCC(C(=O)O)N)NC(=O)C
  External Link
Pubchem ID 71511839
CAS Number 1262780-97-1
CHEBI ID 134700
TTD ID D07RYI

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM063  Increased risk of hypocalcemia
  Relation Graph
 Full list of drugs interacting with Etelcalcetide
      Pharmacodynamic additive effects
   Increased risk of hypocalcemia Drug Num:  20
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0034
 
Alendronic acid
 
C4H13NO7P2
 
2088 
Major    Inter Info   
[1], [2]
D0055
 
Amifostine
 
C5H15N2O3PS
 
2141 
Major    Inter Info   
[1]
D0217
 
Bumetanide
 
C17H20N2O5S
 
2471 
Major    Inter Info   
[1]
D0338
 
Cinacalcet
 
C22H22F3N
 
156419 
Major    Inter Info   
[1]
D0344
 
Cisplatin
 
Cl2H6N2Pt
 
5702198 
Major    Inter Info   
[1]
D0443
 
Denosumab
 
NA
 
NA
Major    Inter Info   
[3], [4]
D0613
 
Etacrynic acid
 
C13H12Cl2O4
 
3278 
Major    Inter Info   
[1], [2]
D0623
 
Etidronic acid
 
C2H8O7P2
 
3305 
Major    Inter Info   
[1], [2]
D0694
 
Foscarnet
 
CH3O5P
 
3415 
Major    Inter Info   
[1]
D0704
 
Furosemide
 
C12H11ClN2O5S
 
3440 
Major    Inter Info   
[1]
D0783
 
Ibandronate
 
C9H23NO7P2
 
60852 
Major    Inter Info   
[1]
D1217
 
Pamidronic acid
 
C3H11NO7P2
 
4674 
Major    Inter Info   
[1], [2]
D1246
 
Pentamidine
 
C19H24N4O2
 
4735 
Major    Inter Info   
[1]
D1412
 
Risedronic acid
 
C7H11NO7P2
 
5245 
Major    Inter Info   
[1], [2]
D1426
 
Romosozumab
 
NA
 
NA
Major    Inter Info   
[1]
D1441
 
Salmon calcitonin
 
C145H240N44O48S2
 
16129616 
Major    Inter Info   
[1], [2]
D1584
 
Tiludronic acid
 
C7H9ClO6P2S
 
60937 
Major    Inter Info   
[1], [2]
D1611
 
Torasemide
 
C16H20N4O3S
 
41781 
Major    Inter Info   
[1], [2]
D1727
 
Zoledronic acid
 
C5H10N2O7P2
 
68740 
Major    Inter Info   
[1]
D0221
 
Burosumab
 
NA
 
NA
Moderate    Inter Info   
[5]
References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Product Information. Skelid (tilundronate). Sanofi Winthrop Pharmaceuticals, New York, NY.
3 Cerner Multum, Inc. "Australian Product Information.".
4 Product Information. Prolia (denosumab). Amgen USA, Thousand Oaks, CA.
5 EMA. European Medicines Agency. European Union "EMA - List of medicines under additional monitoring.".