Details of Drug

Drug General Information (ID: D0516)
Drug Name	Donepezil
Drug Type	Small molecule
Drug Synonymous	Donepezil (transdermal patch, Alzheimer's disease) Click to Show/Hide
Disease Class	8A20: Alzheimer disease
Therapeutic Class	Cholinesterase Inhibitors
Structure
Structure	3D Structure		2D Structure
Formula	C24H29NO3
InChI	1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
InChIKey	ADEBPBSSDYVVLD-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC
External Link
	Pubchem ID	3152
	CAS Number	120014-06-4
	CHEBI ID	53289
	TTD ID	D0NS6H
	VARIDT ID	DR00817

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM004 Affected intra/extra-hepatic metabolism AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM017 CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM037 Additive cholinergic effects BM045 Additive neuromuscular blocking effects BM049 Increased risk of atrioventricular block BM051 Increased risk of bradycardia BM054 Increased risk of GI mucosal injury/bleeding risk BM069 Increased risk of lowers seizure threshold BM076 Increased risk of prolong QT interval BM081 Increased risk of ventricular arrhythmias BM091 Antagonize the effect of cholinergic agents
Relation Graph

Full list of drugs interacting with Donepezil
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 90
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0220		Bupropion	C13H18ClNO	444	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19]
D0002		Abametapir (topical)	C12H12N2	15664	Moderate		Inter Info	[44]
D0699		Fostamatinib	C23H26FN6O9P	11671467	Moderate		Inter Info	[57]
D0960		Lumefantrine	C30H32Cl3NO	6437380	Moderate		Inter Info	[26], [30], [69]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[78]
D0080		Amprenavir	C25H35N3O6S	65016	Minor		Inter Info	[31], [105], [106], [68]
D0100		Aprepitant	C23H21F7N4O3	135413536	Minor		Inter Info	[31], [105], [106], [68]
D0298		Celecoxib	C17H14F3N3O2S	2662	Minor		Inter Info	[31], [105], [106], [68]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Minor		Inter Info	[31], [105], [106], [68]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Minor		Inter Info	[31], [105], [106], [68]
D0356		Clobazam	C16H13ClN2O2	2789	Minor		Inter Info	[31], [105], [106], [68]
D0367		Clotrimazole	C22H17ClN2	2812	Minor		Inter Info	[31], [105], [106], [68]
D0439		Delavirdine	C22H28N6O3S	5625	Minor		Inter Info	[31], [105], [106], [68]
D0467		Dextropropoxyphene	C22H29NO2	10100	Minor		Inter Info	[31], [106], [68]
D0007		Abiraterone	C24H31NO	132971	Minor		Inter Info	[31], [105], [106], [68]
D0171		Berotralstat	C30H26F4N6O	137528262	Minor		Inter Info	[31], [105], [106], [68]
D0180		Bicalutamide	C18H14F4N2O4S	2375	Minor		Inter Info	[31], [105], [106], [68]
D0192		Boceprevir	C27H45N5O5	10324367	Minor		Inter Info	[31], [105], [106], [68]
D0338		Cinacalcet	C22H22F3N	156419	Minor		Inter Info	[31], [105], [106], [68]
D0349		Clarithromycin	C38H69NO13	84029	Minor		Inter Info	[31], [105], [106], [68]
D0375		Cobicistat	C40H53N7O5S2	25151504	Minor		Inter Info	[31], [105], [106], [68]
D0386		Conivaptan	C32H26N4O2	151171	Minor		Inter Info	[31], [105], [106], [68]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Minor		Inter Info	[31], [105], [106], [68]
D0409		Dacomitinib	C24H25ClFN5O2	11511120	Minor		Inter Info	[31], [105], [106], [68]
D0413		Dalfopristin	C34H50N4O9S	6323289	Minor		Inter Info	[31], [106], [68]
D0416		Danazol	C22H27NO2	28417	Minor		Inter Info	[31], [105], [106], [68]
D0426		Darunavir	C27H37N3O7S	213039	Minor		Inter Info	[31], [105], [106], [68]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Minor		Inter Info	[31], [105], [106], [68]
D0457		Dexfenfluramine	C12H16F3N	66265	Minor		Inter Info	[31], [105], [106], [68]
D0543		Duvelisib	C22H17ClN6O	50905713	Minor		Inter Info	[31], [105], [106], [68]
D0559		Eliglustat	C23H36N2O4	23652731	Minor		Inter Info	[31], [105], [106], [68]
D0629		Everolimus	C53H83NO14	6442177	Minor		Inter Info	[31], [105], [106], [68]
D0638		Fedratinib	C27H36N6O3S	16722836	Minor		Inter Info	[31], [105], [106], [68]
D0692		Fosamprenavir	C25H36N3O9PS	131536	Minor		Inter Info	[31], [105], [106], [68]
D0693		Fosaprepitant	C23H22F7N4O6P	135413538	Minor		Inter Info	[31], [105], [106], [68]
D0724		Givosiran	C78H139N11O30	119058042	Minor		Inter Info	[31], [105], [106], [68]
D0732		Glycerol phenylbutyrate	C33H38O6	10482134	Minor		Inter Info	[31], [105], [106], [68]
D0735		Goldenseal	NA	NA	Minor		Inter Info	[31], [105], [106], [68]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Minor		Inter Info	[31], [105], [106], [68]
D0789		Idelalisib	C22H18FN7O	11625818	Minor		Inter Info	[31], [105], [106], [68]
D0852		Isavuconazonium	C35H35F2N8O5S+	6918606	Minor		Inter Info	[31], [105], [106], [68]
D0858		Isoniazid	C6H7N3O	3767	Minor		Inter Info	[31], [105], [106], [68]
D0869		Ivacaftor	C24H28N2O3	16220172	Minor		Inter Info	[31], [105], [106], [68]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Minor		Inter Info	[31], [105], [106], [68]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Minor		Inter Info	[31], [105], [106], [68]
D0896		Larotrectinib	C21H22F2N6O2	46188928	Minor		Inter Info	[31], [105], [106], [68]
D0906		Letermovir	C29H28F4N4O4	45138674	Minor		Inter Info	[31], [105], [106], [68]
D0944		Lomitapide	C39H37F6N3O2	9853053	Minor		Inter Info	[31], [105], [106], [68]
D0946		Lonafarnib	C27H31Br2ClN4O2	148195	Minor		Inter Info	[31], [105], [106], [68]
D0952		Lorcaserin	C11H14ClN	11658860	Minor		Inter Info	[31], [105], [106], [68]
D1057		Miconazole	C18H14Cl4N2O	4189	Minor		Inter Info	[31], [105], [106], [68]
D1074		Mirabegron	C21H24N4O2S	9865528	Minor		Inter Info	[31], [105], [106], [68]
D1117		Nefazodone	C25H32ClN5O2	4449	Minor		Inter Info	[31], [105], [106], [68]
D1136		Nilotinib	C28H22F3N7O	644241	Minor		Inter Info	[31], [105], [106], [68]
D1194		Oxamniquine	C14H21N3O3	4612	Minor		Inter Info	[31], [105], [106], [68]
D1214		Palbociclib	C24H29N7O2	5330286	Minor		Inter Info	[31], [105], [106], [68]
D1221		Panobinostat	C21H23N3O2	6918837	Minor		Inter Info	[31], [105], [106], [68]
D1232		Pazopanib	C21H23N7O2S	10113978	Minor		Inter Info	[1], [26], [30], [31], [32], [33]
D1315		Posaconazole	C37H42F2N8O4	468595	Minor		Inter Info	[31], [105], [106], [68]
D1339		Primaquine	C15H21N3O	4908	Minor		Inter Info	[31], [105], [106], [68]
D1353		Propafenone	C21H27NO3	4932	Minor		Inter Info	[31], [105], [106], [68]
D1398		Ribociclib	C23H30N8O	44631912	Minor		Inter Info	[1], [26], [30], [31], [32], [33]
D1423		Rolapitant	C25H26F6N2O2	10311306	Minor		Inter Info	[31], [105], [106], [68]
D1461		Sertraline	C17H17Cl2N	68617	Minor		Inter Info	[31], [105], [106], [68]
D1541		Telaprevir	C36H53N7O6	3010818	Minor		Inter Info	[31], [105], [106], [68]
D1544		Telithromycin	C43H65N5O10	3002190	Minor		Inter Info	[31], [105], [106], [68]
D1553		Terbinafine	C21H25N	1549008	Minor		Inter Info	[31], [105], [106], [68]
D1653		Troleandomycin	C41H67NO15	202225	Minor		Inter Info	[31], [105], [106], [68]
D1660		Tucatinib	C26H24N8O2	51039094	Minor		Inter Info	[31], [105], [106], [68]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Minor		Inter Info	[31], [105], [106], [68]
D1709		Voxelotor	C19H19N3O3	71602803	Minor		Inter Info	[31], [105], [106], [68]
D0539		Duloxetine	C18H19NOS	60835	Minor		Inter Info	[31], [105], [106], [68]
D0597		Erythromycin	C37H67NO13	12560	Minor		Inter Info	[31], [105], [106], [68]
D0641		Fenfluramine	C12H16F3N	3337	Minor		Inter Info	[31], [105], [106], [68]
D0667		Fluconazole	C13H12F2N6O	3365	Minor		Inter Info	[31], [105], [106], [68]
D0676		Fluoxetine	C17H18F3NO	3386	Minor		Inter Info	[31], [105], [106], [68]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Minor		Inter Info	[31], [105], [106], [68]
D0713		Gefitinib	C22H24ClFN4O3	123631	Minor		Inter Info	[31], [105], [106], [68]
D0793		Imatinib	C29H31N7O	5291	Minor		Inter Info	[31], [105], [106], [68]
D0799		Indinavir	C36H47N5O4	5362440	Minor		Inter Info	[31], [105], [106], [68]
D1017		Methadone	C21H27NO	4095	Minor		Inter Info	[31], [105], [106], [68]
D1063		Mifepristone	C29H35NO2	55245	Minor		Inter Info	[31], [105], [106], [68]
D1119		Nelfinavir	C32H45N3O4S	64143	Minor		Inter Info	[31], [105], [106], [68]
D1229		Paroxetine	C19H20FNO3	43815	Minor		Inter Info	[31], [105], [106], [68]
D1372		Quinine	C20H24N2O2	3034034	Minor		Inter Info	[31], [105], [106], [68]
D1383		Ranolazine	C24H33N3O4	56959	Minor		Inter Info	[31], [105], [106], [68]
D1415		Ritonavir	C37H48N6O5S2	392622	Minor		Inter Info	[31], [105], [106], [68]
D1581		Ticlopidine	C14H14ClNS	5472	Minor		Inter Info	[31], [105], [106], [68]
D1706		Voriconazole	C16H14F3N5O	71616	Minor		Inter Info	[31], [105], [106], [68]
D1714		Zafirlukast	C31H33N3O6S	5717	Minor		Inter Info	[31], [105], [106], [68]
	CYP450 enzyme induction					Drug Num: 41
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0061		Aminoglutethimide	C13H16N2O2	2145	Moderate		Inter Info	[31]
D0178		Bexarotene	C24H28O2	82146	Moderate		Inter Info	[31]
D0194		Bosentan	C27H29N5O6S	104865	Moderate		Inter Info	[43]
D0224		Butabarbital	C10H16N2O3	2479	Moderate		Inter Info	[31]
D0225		Butalbital	C11H16N2O3	2481	Moderate		Inter Info	[31]
D0071		Amobarbital	C11H18N2O3	2164	Moderate		Inter Info	[31]
D0095		Apalutamide	C21H15F4N5O2S	24872560	Moderate		Inter Info	[31]
D0300		Cenobamate	C10H10ClN5O2	11962412	Moderate		Inter Info	[31]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[30], [50]
D0432		Deferasirox	C21H15N3O4	214348	Moderate		Inter Info	[31]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[31]
D0545		Echinacea	NA	NA	Moderate		Inter Info	[26], [51]
D0555		Elagolix	C32H30F5N3O5	11250647	Moderate		Inter Info	[31]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[31]
D0601		Eslicarbazepine	C15H14N2O2	9881504	Moderate		Inter Info	[26], [52], [30], [53]
D0628		Etravirine	C20H15BrN6O	193962	Moderate		Inter Info	[54]
D0697		Fosphenytoin	C16H15N2O6P	56339	Moderate		Inter Info	[31]
D0872		Ivosidenib	C28H22ClF3N6O3	71657455	Moderate		Inter Info	[31]
D0901		Lemborexant	C22H20F2N4O2	56944144	Moderate		Inter Info	[31], [68]
D0958		Lumacaftor	C24H18F2N2O5	16678941	Moderate		Inter Info	[31], [68]
D1040		Methylphenobarbital	C13H14N2O3	8271	Moderate		Inter Info	[31], [68]
D1258		Pexidartinib	C20H15ClF3N5	25151352	Moderate		Inter Info	[31]
D1265		Phenobarbital	C12H12N2O3	4763	Moderate		Inter Info	[31]
D1401		Rifapentine	C47H64N4O12	135403821	Moderate		Inter Info	[72], [73]
D1502		St. John's Wort	NA	NA	Moderate		Inter Info	[31]
D1538		Tazemetostat	C34H44N4O4	66558664	Moderate		Inter Info	[31]
D1546		Telotristat ethyl	C27H26ClF3N6O3	25181577	Moderate		Inter Info	[30], [74]
D0554		Efavirenz	C14H9ClF3NO2	64139	Moderate		Inter Info	[77]
D0741		Griseofulvin	C17H17ClO6	441140	Moderate		Inter Info	[31]
D1078		Mitotane	C14H10Cl4	4211	Moderate		Inter Info	[31]
D1099		Nafcillin	C21H22N2O5S	8982	Moderate		Inter Info	[31]
D1128		Nevirapine	C15H14N4O	4463	Moderate		Inter Info	[31]
D1198		Oxcarbazepine	C15H12N2O2	34312	Moderate		Inter Info	[82], [83], [84]
D1248		Pentobarbital	C11H18N2O3	4737	Moderate		Inter Info	[31]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[31]
D1283		Phenytoin	C15H12N2O2	1775	Moderate		Inter Info	[31]
D1340		Primidone	C12H14N2O2	4909	Moderate		Inter Info	[31]
D1399		Rifabutin	C46H62N4O11	135398743	Moderate		Inter Info	[31]
D1453		Secobarbital	C12H18N2O3	5193	Moderate		Inter Info	[31]
D1652		Troglitazone	C24H27NO5S	5591	Moderate		Inter Info	[98], [99], [100], [101], [102], [103], [104]
D0106		Armodafinil	C15H15NO2S	9690109	Minor		Inter Info	[108], [109], [110], [111], [112]
Pharmacodynamic additive effects
	Additive cholinergic effects					Drug Num: 10
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0052		Ambenonium	C28H42Cl2N4O2+2	2131	Moderate		Inter Info	[31], [40], [42]
D0054		Amifampridine	C5H7N3	5918	Moderate		Inter Info	[47], [48]
D0175		Bethanechol	C7H17N2O2+	2370	Moderate		Inter Info	[31], [40], [42]
D0552		Edrophonium	C10H16NO+	3202	Moderate		Inter Info	[31], [40], [42]
D1122		Neostigmine	C12H19N2O2+	4456	Moderate		Inter Info	[31], [40], [42]
D1285		Physostigmine	C15H21N3O2	5983	Moderate		Inter Info	[31], [40], [42]
D1418		Rivastigmine	C14H22N2O2	77991	Moderate		Inter Info	[31], [40], [42]
D0707		Galantamine	C17H21NO3	9651	Moderate		Inter Info	[31], [40], [42]
D0746		Guanidine	CH5N3	3520	Moderate		Inter Info	[31], [40], [42]
D1365		Pyridostigmine	C9H13N2O2+	4991	Moderate		Inter Info	[31], [40], [42]
	Additive neuromuscular blocking effects					Drug Num: 12
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1510		Succinylcholine	C14H30N2O4+2	5314	Moderate		Inter Info	[95], [96], [97], [31], [42]
D0343		Cisatracurium	C53H72N2O12+2	62887	Minor		Inter Info	[30], [31], [107]
D0122		Atracurium	C53H72N2O12+2	47319	Minor		Inter Info	[30], [31], [107]
D0522		Doxacurium	C56H78N2O16+2	60169	Minor		Inter Info	[30], [31], [107]
D1047		Metocurine	C40H48N2O6+2	21233	Minor		Inter Info	[30], [31], [107]
D1080		Mivacurium	C58H80N2O14+2	5281042	Minor		Inter Info	[30], [31], [107]
D1219		Pancuronium	C35H60N2O4+2	441289	Minor		Inter Info	[30], [31], [107]
D1295		Pipecuronium	C35H62N4O4+2	50192	Minor		Inter Info	[30], [31], [107]
D1384		Rapacuronium	C37H61N2O4+	5311399	Minor		Inter Info	[30], [31], [107]
D1659		Tubocurarine	C37H41N2O6+	6000	Minor		Inter Info	[30], [31], [107]
D1684		Vecuronium	C34H57N2O4+	39765	Minor		Inter Info	[30], [31], [107]
D1420		Rocuronium	C32H53N2O4+	441290	Minor		Inter Info	[30], [31], [107]
	Increased risk of bradycardia					Drug Num: 41
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1474		Siponimod	C29H35F3N2O3	44599207	Major		Inter Info	[26], [27]
D0069		Amlodipine	C20H25ClN2O5	2162	Moderate		Inter Info	[40], [33], [41]
D0117		Atenolol	C14H22N2O3	2249	Moderate		Inter Info	[40], [33], [41]
D0173		Betaxolol	C18H29NO3	2369	Moderate		Inter Info	[40], [33], [41]
D0188		Bisoprolol	C18H31NO4	2405	Moderate		Inter Info	[40], [33], [41]
D0265		Carteolol	C16H24N2O3	2583	Moderate		Inter Info	[40], [33], [41]
D0491		Digoxin	C41H64O14	2724385	Moderate		Inter Info	[40], [33], [41]
D0497		Diltiazem	C22H26N2O4S	39186	Moderate		Inter Info	[40], [33], [41]
D0010		Acebutolol	C18H28N2O4	1978	Moderate		Inter Info	[40], [33], [41]
D0031		Alectinib	C30H34N4O2	49806720	Moderate		Inter Info	[45], [46]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[40], [33], [41]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[40], [33], [41]
D0170		Bepridil	C24H34N2O	2351	Moderate		Inter Info	[40], [33], [41]
D0204		Brigatinib	C29H39ClN7O2P	68165256	Moderate		Inter Info	[49]
D0267		Carvedilol	C24H26N2O4	2585	Moderate		Inter Info	[40], [33], [41]
D0352		Clevidipine	C21H23Cl2NO6	153994	Moderate		Inter Info	[40], [33], [41]
D0490		Digitoxin	C41H64O13	441207	Moderate		Inter Info	[40], [33], [41]
D0534		Dronedarone	C31H44N2O5S	208898	Moderate		Inter Info	[40], [33], [41]
D0661		Fingolimod	C19H33NO2	107970	Moderate		Inter Info	[55], [56]
D0868		Ivabradine	C27H36N2O5	132999	Moderate		Inter Info	[26], [66]
D0885		Lacosamide	C13H18N2O3	219078	Moderate		Inter Info	[40], [33], [41]
D0897		Lasmiditan	C19H18F3N3O2	11610526	Moderate		Inter Info	[67]
D0911		Levamlodipine	C20H25ClN2O5	9822750	Moderate		Inter Info	[40], [33], [41]
D0948		Lopinavir	C37H48N4O5	92727	Moderate		Inter Info	[40], [33], [41]
D1098		Nadolol	C17H27NO4	39147	Moderate		Inter Info	[40], [33], [41]
D1114		Nebivolol	C22H25F2NO4	71301	Moderate		Inter Info	[40], [33], [41]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[40], [33], [41]
D1244		Penbutolol	C18H29NO2	37464	Moderate		Inter Info	[40], [33], [41]
D1293		Pindolol	C14H20N2O2	4828	Moderate		Inter Info	[40], [33], [41]
D1444		Saquinavir	C38H50N6O5	441243	Moderate		Inter Info	[40], [33], [41]
D1600		Tofacitinib	C16H20N6O	9926791	Moderate		Inter Info	[26], [76]
D0602		Esmolol	C16H25NO4	59768	Moderate		Inter Info	[40], [33], [41]
D0865		Isradipine	C19H21N3O5	3784	Moderate		Inter Info	[40], [33], [41]
D0884		Labetalol	C19H24N2O3	3869	Moderate		Inter Info	[40], [33], [41]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[40], [33], [41]
D1049		Metoprolol	C15H25NO3	4171	Moderate		Inter Info	[40], [33], [41]
D1088		Moricizine	C22H25N3O4S	34633	Moderate		Inter Info	[40], [33], [41]
D1130		Nicardipine	C26H29N3O6	4474	Moderate		Inter Info	[40], [33], [41]
D1498		Sotalol	C12H20N2O3S	5253	Moderate		Inter Info	[40], [33], [41]
D1585		Timolol	C13H24N4O3S	33624	Moderate		Inter Info	[40], [33], [41]
D1690		Verapamil	C27H38N2O4	2520	Moderate		Inter Info	[40], [33], [41]
	Increased risk of GI mucosal injury/bleeding risk					Drug Num: 23
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0476		Diclofenac	C14H11Cl2NO2	3033	Minor		Inter Info	[31]
D0017		Acetylsalicylic acid	C9H8O4	2244	Minor		Inter Info	[31]
D0187		Bismuth subsalicylate	C7H6BiO4	16682734	Minor		Inter Info	[31]
D0331		Choline salicylate	C12H19NO4	54686350	Minor		Inter Info	[31]
D0489		Diflunisal	C13H8F2O3	3059	Minor		Inter Info	[31]
D0786		Ibuprofen	C13H18O2	3672	Minor		Inter Info	[31]
D0881		Ketoprofen	C16H14O3	3825	Minor		Inter Info	[31]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Minor		Inter Info	[31]
D1196		Oxaprozin	C18H15NO3	4614	Minor		Inter Info	[31]
D1439		Salicylic acid (sodium)	C7H6O3	338	Minor		Inter Info	[31]
D1442		Salsalate	C14H10O5	5161	Minor		Inter Info	[31]
D0624		Etodolac	C17H21NO3	3308	Minor		Inter Info	[31]
D0645		Fenoprofen	C15H14O3	3342	Minor		Inter Info	[31]
D0680		Flurbiprofen	C15H13FO2	3394	Minor		Inter Info	[31]
D0800		Indomethacin	C19H16ClNO4	3715	Minor		Inter Info	[31]
D0882		Ketorolac	C15H13NO3	3826	Minor		Inter Info	[31]
D0991		Mefenamic acid	C15H15NO2	4044	Minor		Inter Info	[31]
D0995		Meloxicam	C14H13N3O4S2	54677470	Minor		Inter Info	[31]
D1097		Nabumetone	C15H16O2	4409	Minor		Inter Info	[31]
D1109		Naproxen	C14H14O3	156391	Minor		Inter Info	[31]
D1300		Piroxicam	C15H13N3O4S	54676228	Minor		Inter Info	[31]
D1520		Sulindac	C20H17FO3S	1548887	Minor		Inter Info	[31]
D1606		Tolmetin	C15H15NO3	5509	Minor		Inter Info	[31]
	Increased risk of lowers seizure threshold					Drug Num: 7
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0833		Iohexol	C19H26I3N3O9	3730	Major		Inter Info	[20], [21], [22], [23], [24]
D0834		Iopamidol	C17H22I3N3O8	65492	Major		Inter Info	[20], [21], [22], [23], [24]
D1616		Tramadol	C16H25NO2	33741	Major		Inter Info	[28], [9], [15], [29]
D0722		Ginkgo biloba	NA	NA	Moderate		Inter Info	[58], [59], [60], [61], [62], [63], [64], [65]
D1287		Picosulfuric acid	C18H15NO8S2	5243	Moderate		Inter Info	[70], [71], [30]
D1308		Polyethylene glycol (3350 with electrolytes)	C2H6O2	174	Moderate		Inter Info	[70], [71], [30]
D0932		Lindane	C6H6Cl6	727	Moderate		Inter Info	[79], [80], [81]
	Increased risk of prolong QT interval					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0937		Lisdexamfetamine	C15H25N3O	11597698	Moderate		Inter Info	[30]
D1356		Propofol	C12H18O	4943	Moderate		Inter Info	[85], [86], [87], [88], [89], [90], [91], [92], [93], [94]
	Increased risk of ventricular arrhythmias					Drug Num: 98
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1211		Ozanimod	C23H24N4O3	52938427	Major		Inter Info	[25]
D0003		Abarelix	C72H95ClN14O14	16131215	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0084		Anagrelide	C10H7Cl2N3O	135409400	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0097		Apomorphine	C17H17NO2	6005	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0115		Astemizole	C28H31FN4O	2247	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0139		Azithromycin	C38H72N2O12	447043	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0342		Cisapride	C23H29ClFN3O4	6917698	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0429		Daunorubicin	C27H29NO10	30323	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Moderate		Inter Info	[26], [32], [33]
D0514		Dolasetron	C19H20N2O3	3033818	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0107		Arsenic trioxide	As2O3	14888	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0230		Cabozantinib	C28H24FN3O5	25102847	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0358		Clofazimine	C27H22Cl2N4	2794	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0437		Degarelix	C82H103ClN18O16	16136245	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0452		Deutetrabenazine	C19H27NO3	73437646	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[26], [32], [33]
D0577		Entrectinib	C31H34F2N6O2	25141092	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0632		Ezogabine	C16H18FN3O2	121892	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0636		Famotidine	C8H15N7O2S3	5702160	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0664		Flecainide	C17H20F6N2O3	3356	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0700		Fostemsavir	C25H26N7O8P	11319217	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0725		Glasdegib	C21H22N6O	25166913	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0751		Halothane	C2HBrClF3	3562	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0758		Histrelin	C66H86N18O12	25077993	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0788		Idarubicin	C26H27NO9	42890	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0791		Iloperidone	C24H27FN2O4	71360	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0806		Inotuzumab ozogamicin	NA	NA	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0899		Lefamulin	C28H45NO5S	25185057	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0909		Levacetylmethadol	C23H31NO2	15130	Moderate		Inter Info	[26], [32], [33]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0940		Lithium carbonate	CLi2O3	11125	Moderate		Inter Info	[26], [32], [33]
D0942		Lofexidine	C11H12Cl2N2O	30668	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0965		Macimorelin	C26H30N6O3	9804938	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1051		Metronidazole	C6H9N3O3	4173	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1171		Olodaterol	C21H26N2O5	11504295	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1181		Ondansetron	C18H19N3O	4595	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1189		Osilodrostat	C13H10FN3	44139752	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1190		Osimertinib	C28H33N7O2	71496458	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1215		Paliperidone	C23H27FN4O3	115237	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1230		Pasireotide	C58H66N10O9	9941444	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1290		Pimavanserin	C25H34FN3O2	10071196	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1302		Pitolisant	C17H26ClNO	9948102	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1342		Probucol	C31H48O2S2	4912	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1388		Relugolix	C29H27F2N7O5S	10348973	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1438		Salbutamol	C13H21NO3	2083	Moderate		Inter Info	[26], [32], [33]
D1459		Selpercatinib	C29H31N7O3	134436906	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1463		Sevoflurane	C4H3F7O	5206	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1542		Telavancin	C80H106Cl2N11O27P	3081362	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1554		Terbutaline	C12H19NO3	5403	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1560		Tetrabenazine	C19H27NO3	6018	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[26], [30], [75]
D1634		Triclabendazole	C14H9Cl3N2OS	50248	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1651		Triptorelin	C64H82N18O13	25074470	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1673		Valbenazine	C24H38N2O4	24795069	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1681		Vandetanib	C22H24BrFN4O2	3081361	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0535		Droperidol	C22H22FN3O2	3168	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0737		Goserelin	C59H84N18O14	5311128	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0787		Ibutilide	C20H36N2O3S	60753	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D0908		Leuprolide	C59H84N16O12	657181	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1210		Oxytocin	C43H66N12O12S2	439302	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1246		Pentamidine	C19H24N4O2	4735	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1254		Perflutren	C3F8	6432	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1497		Sorafenib	C21H16ClF3N4O3	216239	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1533		Tamoxifen	C26H29NO	2733526	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1555		Terfenadine	C32H41NO2	5405	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1596		Tizanidine	C9H8ClN5S	5487	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1612		Toremifene	C26H28ClNO	3005573	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1683		Vasopressin	C46H65N15O12S2	644077	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[1], [26], [30], [31], [32], [33]
Pharmacodynamic antagonistic effects
	Antagonize the effect of cholinergic agents					Drug Num: 86
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0068		Amitriptyline	C20H23N	2160	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0072		Amoxapine	C17H16ClN3O	2170	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0124		Atropine (ophthalmic)	C17H23NO3	174174	Moderate		Inter Info	[38], [31], [39]
D0135		Azatadine	C20H22N2	19861	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0160		Benzatropine	C21H25NO	1201549	Moderate		Inter Info	[38], [31], [39]
D0183		Biperiden	C21H29NO	2381	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0214		Brompheniramine	C16H19BrN2	6834	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0255		Carbamazepine	C15H12N2O	2554	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0259		Carbinoxamine	C16H19ClN2O	2564	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0337		Cimetidine	C10H16N6S	2756	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0351		Clemastine	C21H26ClNO	26987	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0353		Clidinium	C22H26NO3+	2784	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0370		Clozapine	C18H19ClN4	135398737	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0403		Cyproheptadine	C21H21N	2913	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0424		Darifenacin	C28H30N2O2	444031	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0456		Dexbrompheniramine	C16H19BrN2	16960	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0482		Dicyclomine	C19H35NO2	3042	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0508		Disopyramide	C21H29N3O	3114	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0020		Acrivastine	C22H24N2O2	5284514	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[35], [36], [38]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0154		Belladonna	C34H42N2O4	265028	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0202		Brexpiprazole	C25H27N3O2S	11978813	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0316		Chlorcyclizine	C18H21ClN2	2710	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0323		Chlorpheniramine	C16H19ClN2	2725	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0397		Cyclizine	C18H22N2	6726	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0398		Cyclobenzaprine	C20H21N	2895	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0399		Cyclopentolate (ophthalmic)	C17H25NO3	2905	Moderate		Inter Info	[38], [31], [39]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0498		Dimenhydrinate	C24H28ClN5O3	10660	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0502		Diphenhydramine	C17H21NO	3100	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0525		Doxepin	C19H21NO	667477	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0526		Doxepin (topical)	C19H21NO	667477	Moderate		Inter Info	[35], [36], [38]
D0662		Flavoxate	C24H25NO4	3354	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0733		Glycopyrronium	C19H28NO3+	3494	Moderate		Inter Info	[38], [31], [39]
D0760		Homatropine (ophthalmic)	C16H21NO3	5282593	Moderate		Inter Info	[38], [31], [39]
D0959		Lumateperone	C24H28FN3O	21302490	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0979		Maprotiline	C20H23N	4011	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1000		Mepenzolate	C21H26NO3+	4057	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1006		Mepyramine	C17H23N3O	4992	Moderate		Inter Info	[35], [36], [38]
D1010		Mesoridazine	C21H26N2OS2	4078	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1019		Methdilazine	C18H20N2S	14677	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1031		Methscopolamine	C18H24NO4+	71183	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1084		Molindone	C16H24N2O2	23897	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1188		Orphenadrine	C18H23NO	4601	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1264		Phenindamine	C19H19N	11291	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1282		Phenyltoloxamine	C17H21NO	7077	Moderate		Inter Info	[35], [36], [38]
D1292		Pimozide	C28H29F2N3O	16362	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1343		Procainamide	C13H21N3O	4913	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1381		Ranitidine	C13H22N4O3S	3001055	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1576		Thiothixene	C23H29N3O2S2	941651	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1607		Tolterodine	C22H31NO	443879	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0532		Doxylamine	C17H22N2O	3162	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0750		Haloperidol	C21H23ClFNO2	3559	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0781		Hydroxyzine	C21H27ClN2O2	3658	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0782		Hyoscyamine	C17H23NO3	154417	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0947		Loperamide	C29H33ClN2O2	3955	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0957		Loxapine	C18H18ClN3O	3964	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D0987		Meclizine	C25H27ClN2	4034	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1158		Nortriptyline	C19H21N	4543	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1166		Olanzapine	C17H20N4S	135398745	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1347		Procyclidine	C19H29NO	4919	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1351		Promazine	C17H20N2S	4926	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1354		Propantheline	C23H30NO3+	4934	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1355		Propiomazine	C20H24N2OS	4940	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1450		Scopolamine	C17H21NO4	3000322	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1451		Scopolamine (ophthalmic)	C17H21NO4	3000322	Moderate		Inter Info	[38], [31], [39]
D1572		Thiethylperazine	C22H29N3S2	5440	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1641		Trihexyphenidyl	C20H31NO	5572	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1647		Trimipramine	C20H26N2	5584	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1649		Tripelennamine	C16H21N3	5587	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1650		Triprolidine	C19H22N2	5282443	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]
D1655		Tropicamide (ophthalmic)	C17H20N2O2	5593	Moderate		Inter Info	[38], [31], [39]
D1656		Trospium	C25H30NO3+	5284632	Moderate		Inter Info	[34], [35], [36], [37], [38], [31], [40], [42], [39]
D1726		Ziprasidone	C21H21ClN4OS	60854	Moderate		Inter Info	[34], [35], [36], [37], [38], [39]

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